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SLC17A6
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  • SUMMARY

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  • SLC17A6
BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Mouse brain, Intensity
Medulla oblongatai

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

56.258
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

50.345
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA Brain:82.6 nTPM
FANTOM5:316.1 Scaled Tags Per Million
Pig:58.7 nTPM
Mouse:86.5 nTPM
Allen mouse:9.2 Expression energy

MEDULLA OBLONGATA - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

, antibody HPA039226
Medulla oblongata mean intensity 56.258
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

FRONT BACK
Nucleus of the solitary tract 40.606
Raphe magnus nucleus 44.045
Cochlear nucleus 23.134
Lateral paragigantocellular nucleus 32.151
Raphe pallidus nucleus 36.622
Facial nucleus 56.258
Hypoglossal nucleus 42.973
Ambiguus nucleus 19.208
External cuneate nucleus 21.784
Inferior olivary nucleus 31.130
Raphe obscures nucleus 12.247
Dorsal motor nucleus of vagus -
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 24.867
Parabrachial nucleus 43.556
Principle sensory trigeminal nucleus 37.142
Locus coeruleus 40.705
Pontine nucleus 25.821
Vestibular nucleus 34.791
Pontine reticular nucleus, oral 38.422
Lateral lemniscus 50.345
Superior paraolivary nucleus 39.095

PONS AND MEDULLA - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

82.6
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 27.7
2188 Female, age 91, both hemispheres 30.6
2301 Female, age 85, both hemispheres 30.5
1984 Male, age 76, both hemispheres 28.9
2090 Male, age 80, both hemispheres 20.9
Area postrema
nTPM: 7.3
2054 Male, age 76, both hemispheres 16.1
2306 Male, age 80, both hemispheres 3.6
2799 Male, age 61, both hemispheres 2.2
Dorsal cochlear nucleus
nTPM: 18.5
2187 Female, age 91, both hemispheres 24.7
2058 Male, age 76, both hemispheres 21.9
2370 Male, age 61, both hemispheres 20.5
2378 Male, age 80, both hemispheres 14.2
2802 Male, age 74, right hemisphere 11.4
Dorsal medullary reticular nucleus
nTPM: 30.9
2040 Female, age 85, both hemispheres 38.3
2373 Male, age 61, both hemispheres 31.9
2088 Male, age 76, both hemispheres 22.5
Dorsal motor vagal complex
nTPM: 16.9
2133 Female, age 91, both hemispheres 25.8
2813 Female, age 72, unknown 22.0
2844 Male, age 55, unknown 17.5
2000 Male, age 74, unknown 17.1
2807 Female, age 85, both hemispheres 15.0
2797 Male, age 61, both hemispheres 14.8
2185 Male, age 76, both hemispheres 13.7
2643 Male, age 74, both hemispheres 9.4
Dorsal tegmental nucleus
nTPM: 16.9
1936 Male, age 76, left hemisphere 21.7
2083 Male, age 80, both hemispheres 19.3
2358 Male, age 61, both hemispheres 16.9
2326 Male, age 74, both hemispheres 9.6
Dorsolateral tegmental area
nTPM: 15.7
2751 Female, age 85, both hemispheres 39.4
2654 Male, age 80, both hemispheres 18.2
2360 Male, age 74, both hemispheres 9.3
2141 Male, age 76, both hemispheres 6.6
2337 Male, age 61, both hemispheres 4.8
Gigantocellular reticular nuclei, medullary
nTPM: 38.7
2462 Male, age 74, both hemispheres 97.8
2310 Male, age 80, both hemispheres 34.2
2314 Male, age 61, both hemispheres 28.6
2022 Male, age 76, right hemisphere 27.2
1876 Female, age 85, both hemispheres 22.6
2387 Female, age 91, both hemispheres 21.7
Gigantocellular reticular nuclei, pars
nTPM: 36.2
2168 Male, age 76, both hemispheres 74.7
2336 Male, age 61, both hemispheres 39.3
2706 Male, age 80, both hemispheres 30.4
2330 Male, age 80, both hemispheres 29.9
2084 Female, age 85, both hemispheres 6.7
Inferior olive
nTPM: 27.2
2085 Female, age 85, both hemispheres 68.7
2178 Male, age 61, both hemispheres 20.8
2379 Male, age 80, both hemispheres 19.9
2628 Female, age 91, both hemispheres 16.2
2563 Male, age 74, both hemispheres 10.5
Kolliker-Fuse nucleus
nTPM: 23.4
2793 Female, age 91, left hemisphere 29.6
2315 Male, age 76, right hemisphere 24.1
2163 Male, age 80, both hemispheres 16.6
Lateral lemniscal nuclei
nTPM: 66.8
2453 Male, age 74, right hemisphere 90.6
2169 Male, age 76, both hemispheres 83.6
2036 Male, age 80, both hemispheres 69.5
2746 Female, age 85, left hemisphere 53.4
2320 Female, age 91, left hemisphere 37.0
Lateral medullary reticular nucleus
nTPM: 32.2
2044 Male, age 76, both hemispheres 50.8
2374 Male, age 61, both hemispheres 45.8
2190 Female, age 85, both hemispheres 42.7
2804 Female, age 91, both hemispheres 24.2
2305 Male, age 74, both hemispheres 19.0
2852 Male, age 80, both hemispheres 10.7
Lateral parabrachial nucleus
nTPM: 37.7
2139 Female, age 85, right hemisphere 70.2
2013 Male, age 80, both hemispheres 38.2
2790 Male, age 61, both hemispheres 28.2
2792 Male, age 76, both hemispheres 14.3
Lateral vestibular nucleus
nTPM: 16.1
2311 Male, age 80, both hemispheres 16.5
2184 Male, age 76, both hemispheres 15.8
Locus coeruleus
nTPM: 25.0
2123 Female, age 91, both hemispheres 37.3
2788 Male, age 74, unknown 33.6
2162 Male, age 80, both hemispheres 25.9
2014 Male, age 55, unknown 21.4
2720 Male, age 74, both hemispheres 19.5
2317 Female, age 72, unknown 19.3
1980 Male, age 76, both hemispheres 17.8
Medial olivary nucleus
nTPM: 9.8
1962 Male, age 76, both hemispheres 15.1
2851 Male, age 80, both hemispheres 13.7
2138 Female, age 91, both hemispheres 7.3
1943 Male, age 61, both hemispheres 3.2
Medial parabrachial nucleus
nTPM: 25.9
2854 Male, age 80, both hemispheres 35.4
2463 Female, age 85, right hemisphere 32.6
2170 Female, age 91, both hemispheres 29.0
2156 Male, age 61, both hemispheres 19.2
2786 Male, age 76, both hemispheres 13.3
Medial periolivary nuclei
nTPM: 57.3
2171 Female, age 85, both hemispheres 86.5
2063 Male, age 76, both hemispheres 82.0
2791 Male, age 74, right hemisphere 56.4
2458 Female, age 91, both hemispheres 32.3
2081 Male, age 80, both hemispheres 29.4
Medial vestibular nucleus
nTPM: 29.8
2743 Female, age 85, both hemispheres 53.2
2803 Female, age 91, both hemispheres 44.4
2801 Male, age 74, both hemispheres 26.6
2624 Male, age 61, both hemispheres 19.8
2134 Male, age 76, both hemispheres 18.9
2093 Male, age 80, both hemispheres 15.5
Motor facial nucleus
nTPM: 55.1
2062 Male, age 76, both hemispheres 88.8
2327 Male, age 80, both hemispheres 63.2
2365 Male, age 74, right hemisphere 62.8
2697 Female, age 85, both hemispheres 50.4
2795 Female, age 91, both hemispheres 42.8
2126 Male, age 61, both hemispheres 22.9
Motor hypoglossal nucleus
nTPM: 21.8
2125 Female, age 91, both hemispheres 33.6
2461 Male, age 61, both hemispheres 26.1
2132 Female, age 85, both hemispheres 20.7
2277 Male, age 76, both hemispheres 16.7
2182 Male, age 80, both hemispheres 11.9
Motor trigeminal nucleus
nTPM: 34.0
2079 Male, age 80, both hemispheres 57.2
2560 Male, age 74, both hemispheres 42.7
2309 Male, age 76, both hemispheres 24.3
2335 Male, age 61, both hemispheres 23.5
2321 Female, age 91, both hemispheres 22.3
Nuclei of the trapezoid body
nTPM: 74.6
2159 Male, age 61, both hemispheres 120.9
2735 Female, age 85, both hemispheres 85.4
1983 Male, age 76, both hemispheres 77.3
2166 Male, age 80, both hemispheres 48.1
2368 Female, age 91, both hemispheres 41.4
Nucleus ambiguus
nTPM: 23.7
2096 Female, age 85, both hemispheres 28.6
2071 Male, age 76, both hemispheres 18.8
Nucleus cuneatus
nTPM: 20.5
2131 Male, age 76, both hemispheres 43.1
2376 Male, age 61, both hemispheres 33.1
2100 Male, age 76, both hemispheres 31.1
2562 Male, age 61, both hemispheres 25.8
2564 Male, age 74, both hemispheres 15.7
2381 Male, age 80, both hemispheres 13.7
2808 Female, age 85, both hemispheres 9.6
2805 Female, age 91, both hemispheres 6.4
2380 Male, age 80, both hemispheres 6.2
Nucleus gracilis
nTPM: 6.4
2627 Male, age 74, both hemispheres 8.7
2299 Female, age 85, both hemispheres 6.1
2382 Male, age 80, both hemispheres 4.6
Nucleus raphe magnus
nTPM: 82.6
2160 Male, age 61, both hemispheres 145.5
2455 Male, age 74, both hemispheres 103.7
2172 Female, age 85, both hemispheres 93.2
2328 Male, age 80, both hemispheres 57.0
2051 Male, age 76, both hemispheres 50.6
2459 Female, age 91, both hemispheres 45.5
Nucleus raphe obscurus
nTPM: 38.4
2845 Female, age 85, midline 59.0
2800 Male, age 61, midline 56.0
2142 Male, age 76, midline 0.1
Nucleus raphe pallidus
nTPM: 18.5
1924 Male, age 61, midline 30.4
2183 Male, age 80, midline 24.0
2145 Male, age 76, midline 1.1
Nucleus tractus solitarii
nTPM: 28.1
2144 Female, age 91, right hemisphere 55.2
2656 Male, age 76, both hemispheres 31.0
2307 Male, age 80, both hemispheres 16.8
2191 Female, age 85, both hemispheres 9.3
Paramedian reticular nucleus
nTPM: 36.4
2050 Female, age 85, both hemispheres 60.2
2057 Male, age 80, both hemispheres 34.4
2313 Male, age 61, both hemispheres 28.3
2052 Male, age 76, both hemispheres 22.6
Parvicellular reticular nuclei
nTPM: 33.1
2558 Male, age 74, both hemispheres 64.7
2095 Male, age 76, both hemispheres 31.2
2119 Male, age 80, both hemispheres 3.5
Parvicellular reticular nuclei, medullary
nTPM: 26.1
2181 Male, age 80, left hemisphere 28.7
2189 Female, age 91, both hemispheres 27.2
2091 Female, age 85, both hemispheres 22.3
Pedunculopontine tegmental nucleus
nTPM: 26.3
2338 Male, age 61, both hemispheres 30.4
1921 Female, age 85, both hemispheres 29.0
2334 Male, age 80, both hemispheres 19.5
Peritrigeminal nucleus
nTPM: 48.7
2179 Male, age 61, both hemispheres 63.4
2067 Female, age 85, both hemispheres 42.5
2136 Male, age 76, both hemispheres 40.2
Pontine nuclei
nTPM: 70.9
2727 Male, age 61, right hemisphere 137.4
2787 Female, age 85, both hemispheres 80.7
2109 Female, age 72, unknown 77.5
1863 Male, age 55, unknown 77.2
1968 Male, age 76, left hemisphere 71.1
2454 Male, age 74, left hemisphere 59.8
2115 Male, age 80, left hemisphere 32.2
2319 Female, age 91, both hemispheres 31.7
Pontine raphe nucleus
nTPM: 33.1
2122 Female, age 85, midline 63.4
2853 Male, age 76, midline 2.8
Posteroventral cochlear nucleus
nTPM: 23.6
2752 Female, age 85, both hemispheres 47.0
2070 Male, age 76, both hemispheres 36.0
2371 Male, age 61, both hemispheres 17.8
2341 Male, age 80, both hemispheres 15.4
2135 Female, age 91, both hemispheres 1.6
Prepositus hypoglossal nucleus
nTPM: 21.7
2855 Female, age 85, right hemisphere 26.8
2086 Male, age 80, both hemispheres 16.6
Principal sensory trigeminal nucleus
nTPM: 56.8
2158 Male, age 61, both hemispheres 101.1
2008 Male, age 80, left hemisphere 80.1
2367 Female, age 91, left hemisphere 33.5
2324 Male, age 76, both hemispheres 12.3
Reticular pontine nucleus, caudal
nTPM: 39.6
2332 Male, age 80, right hemisphere 61.2
2092 Male, age 76, both hemispheres 55.0
2457 Female, age 91, both hemispheres 36.5
2559 Male, age 74, both hemispheres 5.8
Reticular pontine nucleus, oral
nTPM: 41.9
2361 Male, age 74, both hemispheres 64.1
2012 Female, age 85, both hemispheres 60.8
1939 Male, age 80, both hemispheres 34.6
2366 Female, age 91, both hemispheres 26.0
2167 Male, age 76, both hemispheres 23.8
Reticulotegmental nucleus
nTPM: 30.8
2325 Male, age 76, both hemispheres 44.4
2333 Male, age 80, both hemispheres 28.3
2452 Male, age 74, both hemispheres 27.9
2322 Female, age 91, both hemispheres 22.4
Spinal trigeminal nucleus, caudal
nTPM: 24.2
2447 Male, age 76, both hemispheres 44.4
2312 Male, age 61, both hemispheres 26.9
2308 Male, age 80, both hemispheres 19.2
2642 Male, age 74, both hemispheres 18.4
2390 Female, age 91, both hemispheres 12.0
Spinal trigeminal nucleus, interpolar
nTPM: 41.4
2066 Male, age 76, right hemisphere 75.8
2389 Female, age 91, both hemispheres 53.8
2386 Female, age 85, both hemispheres 42.0
2033 Male, age 80, both hemispheres 24.9
2625 Male, age 61, both hemispheres 10.3
Spinal trigeminal nucleus, oral
nTPM: 20.0
1978 Male, age 76, both hemispheres 22.1
2737 Female, age 85, both hemispheres 19.4
2164 Male, age 80, both hemispheres 18.5
Spinal vestibular nucleus
nTPM: 24.0
2806 Female, age 85, both hemispheres 35.2
2186 Female, age 91, both hemispheres 30.7
2780 Male, age 80, both hemispheres 28.2
2796 Male, age 61, both hemispheres 21.5
2748 Male, age 76, both hemispheres 16.8
2384 Male, age 74, both hemispheres 11.2
Subcoeruleus area
nTPM: 36.1
2089 Male, age 76, left hemisphere 51.3
1958 Male, age 80, both hemispheres 50.2
2323 Female, age 91, left hemisphere 38.8
2369 Female, age 85, left hemisphere 26.7
2451 Male, age 74, both hemispheres 13.2
Superior olive
nTPM: 57.7
1875 Female, age 85, both hemispheres 92.9
2364 Male, age 74, right hemisphere 58.2
2020 Male, age 76, both hemispheres 54.1
2329 Male, age 80, right hemisphere 45.1
2561 Female, age 91, both hemispheres 38.1
Superior vestibular nucleus
nTPM: 16.8
2015 Male, age 80, both hemispheres 23.6
2061 Male, age 76, both hemispheres 16.2
2383 Male, age 74, both hemispheres 10.6
Ventral medullary reticular nucleus
nTPM: 36.5
2372 Male, age 61, both hemispheres 49.4
2060 Male, age 76, both hemispheres 23.6
Ventral periolivary nuclei
nTPM: 63.3
2130 Female, age 85, both hemispheres 80.8
2165 Male, age 80, both hemispheres 68.5
2794 Female, age 91, left hemisphere 53.9
2023 Male, age 76, both hemispheres 49.8
Ventrolateral medulla, A1-C1 cell groups
nTPM: 42.6
2741 Female, age 85, both hemispheres 62.2
2180 Male, age 61, both hemispheres 48.1
1986 Male, age 76, both hemispheres 46.8
2302 Female, age 91, both hemispheres 33.0
2118 Male, age 80, both hemispheres 22.7
Ventrolateral tegmental area, A5 NE cell group
nTPM: 45.2
2449 Male, age 74, both hemispheres 88.7
1959 Male, age 76, both hemispheres 58.4
2161 Male, age 80, both hemispheres 47.0
2840 Female, age 85, both hemispheres 38.0
2456 Female, age 91, both hemispheres 23.2
2359 Male, age 61, both hemispheres 15.8

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

316.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 66.1
FF:10182-103D2 60 years, female 70.5
FF:10165-103B3 76 years, female 61.6
Medulla oblongata
Scaled Tags Per Million: 56.1
FF:10038-101F2 18-64 years, mixed 80.1
FF:10174-103C3 60 years, female 50.2
FF:10155-103A2 76 years, female 37.8
Pons
Scaled Tags Per Million: 316.1
FF:10033-101E6 18-54 years, mixed 316.1

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

58.7
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 36.2
Samples: 4

Max nTPM: 47.6
Min nTPM: 13.2
Sample A Female 39.7
Sample B Female 47.6
Sample C Male 13.2
Sample D Male 44.2
Pons
nTPM: 58.7
Samples: 4

Max nTPM: 129.6
Min nTPM: 14.4
Sample A Female 129.6
Sample B Female 14.4
Sample C Male 57.7
Sample D Male 32.9

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

86.5
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 86.5
Samples: 4

Max nTPM: 92.8
Min nTPM: 82.7
Sample A Male 83.1
Sample B Male 92.8
Sample C Female 82.7
Sample D Female 87.4

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.2
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 9.2
73818754 Antisense, RP_050921_01_E03, Mouse strain C57BL/6J (56 days, male) 9.2
71724696 Antisense, RP_050921_01_E03, Mouse strain C57BL/6J (56 days, male) 5.5
Pons
Expression energy: 8.2
73818754 Antisense, RP_050921_01_E03, Mouse strain C57BL/6J (56 days, male) 8.2
71724696 Antisense, RP_050921_01_E03, Mouse strain C57BL/6J (56 days, male) 4.2

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