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CAPN2
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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Mouse brain, Intensity
Medulla oblongatai

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

213.655
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

181.076
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA Brain:93.3 nTPM
FANTOM5:123.2 Scaled Tags Per Million
Pig:79.1 nTPM
Mouse:64.8 nTPM
Allen mouse:3.1 Expression energy

MEDULLA OBLONGATA - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

, antibody HPA024470
Medulla oblongata mean intensity 213.655
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

FRONT BACK
Nucleus of the solitary tract 125.706
Raphe magnus nucleus 62.008
Cochlear nucleus 62.402
Lateral paragigantocellular nucleus 104.090
Raphe pallidus nucleus 175.745
Facial nucleus 58.317
Hypoglossal nucleus 149.329
Ambiguus nucleus 124.796
External cuneate nucleus 105.556
Inferior olivary nucleus 74.002
Raphe obscures nucleus 97.044
Dorsal motor nucleus of vagus 209.670
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 50.899
Parabrachial nucleus 54.678
Principle sensory trigeminal nucleus 36.238
Locus coeruleus 181.076
Pontine nucleus 43.367
Vestibular nucleus 109.420
Pontine reticular nucleus, oral 30.080
Lateral lemniscus 59.143
Superior paraolivary nucleus 41.010

PONS AND MEDULLA - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

93.3
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 62.3
1984 Male, age 76, both hemispheres 68.5
2301 Female, age 85, both hemispheres 61.9
2090 Male, age 80, both hemispheres 60.9
2188 Female, age 91, both hemispheres 57.8
Area postrema
nTPM: 93.3
2799 Male, age 61, both hemispheres 111.6
2054 Male, age 76, both hemispheres 86.8
2306 Male, age 80, both hemispheres 81.4
Dorsal cochlear nucleus
nTPM: 62.8
2370 Male, age 61, both hemispheres 69.0
2058 Male, age 76, both hemispheres 67.2
2378 Male, age 80, both hemispheres 65.8
2187 Female, age 91, both hemispheres 58.4
2802 Male, age 74, right hemisphere 53.5
Dorsal medullary reticular nucleus
nTPM: 64.1
2088 Male, age 76, both hemispheres 66.6
2373 Male, age 61, both hemispheres 66.4
2040 Female, age 85, both hemispheres 59.3
Dorsal motor vagal complex
nTPM: 68.9
2797 Male, age 61, both hemispheres 84.6
2185 Male, age 76, both hemispheres 82.3
2000 Male, age 74, unknown 75.1
2133 Female, age 91, both hemispheres 66.2
2643 Male, age 74, both hemispheres 63.4
2844 Male, age 55, unknown 62.8
2813 Female, age 72, unknown 61.0
2807 Female, age 85, both hemispheres 55.9
Dorsal tegmental nucleus
nTPM: 71.5
2358 Male, age 61, both hemispheres 76.7
1936 Male, age 76, left hemisphere 73.3
2083 Male, age 80, both hemispheres 70.0
2326 Male, age 74, both hemispheres 66.0
Dorsolateral tegmental area
nTPM: 71.4
2337 Male, age 61, both hemispheres 78.9
2360 Male, age 74, both hemispheres 76.9
2654 Male, age 80, both hemispheres 70.5
2751 Female, age 85, both hemispheres 70.5
2141 Male, age 76, both hemispheres 60.3
Gigantocellular reticular nuclei, medullary
nTPM: 63.6
2314 Male, age 61, both hemispheres 79.3
1876 Female, age 85, both hemispheres 68.3
2387 Female, age 91, both hemispheres 63.4
2022 Male, age 76, right hemisphere 58.1
2462 Male, age 74, both hemispheres 57.4
2310 Male, age 80, both hemispheres 55.0
Gigantocellular reticular nuclei, pars
nTPM: 59.4
2084 Female, age 85, both hemispheres 67.2
2336 Male, age 61, both hemispheres 62.6
2706 Male, age 80, both hemispheres 57.0
2168 Male, age 76, both hemispheres 55.8
2330 Male, age 80, both hemispheres 54.2
Inferior olive
nTPM: 77.9
2379 Male, age 80, both hemispheres 81.5
2178 Male, age 61, both hemispheres 80.5
2563 Male, age 74, both hemispheres 77.9
2085 Female, age 85, both hemispheres 76.8
2628 Female, age 91, both hemispheres 73.0
Kolliker-Fuse nucleus
nTPM: 78.9
2315 Male, age 76, right hemisphere 96.6
2163 Male, age 80, both hemispheres 85.2
2793 Female, age 91, left hemisphere 54.8
Lateral lemniscal nuclei
nTPM: 57.3
2746 Female, age 85, left hemisphere 66.6
2453 Male, age 74, right hemisphere 58.1
2169 Male, age 76, both hemispheres 55.6
2320 Female, age 91, left hemisphere 54.7
2036 Male, age 80, both hemispheres 51.6
Lateral medullary reticular nucleus
nTPM: 73.1
2852 Male, age 80, both hemispheres 79.7
2305 Male, age 74, both hemispheres 75.3
2804 Female, age 91, both hemispheres 74.3
2190 Female, age 85, both hemispheres 71.8
2044 Male, age 76, both hemispheres 69.3
2374 Male, age 61, both hemispheres 68.2
Lateral parabrachial nucleus
nTPM: 69.8
2792 Male, age 76, both hemispheres 76.1
2139 Female, age 85, right hemisphere 68.4
2013 Male, age 80, both hemispheres 68.0
2790 Male, age 61, both hemispheres 66.7
Lateral vestibular nucleus
nTPM: 75.7
2184 Male, age 76, both hemispheres 86.5
2311 Male, age 80, both hemispheres 64.8
Locus coeruleus
nTPM: 60.7
2123 Female, age 91, both hemispheres 66.4
2317 Female, age 72, unknown 66.4
1980 Male, age 76, both hemispheres 64.7
2014 Male, age 55, unknown 59.6
2788 Male, age 74, unknown 59.6
2162 Male, age 80, both hemispheres 59.3
2720 Male, age 74, both hemispheres 49.0
Medial olivary nucleus
nTPM: 80.0
1962 Male, age 76, both hemispheres 83.8
1943 Male, age 61, both hemispheres 82.2
2138 Female, age 91, both hemispheres 80.1
2851 Male, age 80, both hemispheres 73.9
Medial parabrachial nucleus
nTPM: 65.8
2156 Male, age 61, both hemispheres 69.8
2463 Female, age 85, right hemisphere 69.5
2170 Female, age 91, both hemispheres 65.9
2786 Male, age 76, both hemispheres 65.9
2854 Male, age 80, both hemispheres 57.7
Medial periolivary nuclei
nTPM: 58.1
2081 Male, age 80, both hemispheres 62.4
2791 Male, age 74, right hemisphere 59.8
2458 Female, age 91, both hemispheres 57.8
2171 Female, age 85, both hemispheres 56.4
2063 Male, age 76, both hemispheres 54.0
Medial vestibular nucleus
nTPM: 67.9
2134 Male, age 76, both hemispheres 83.5
2624 Male, age 61, both hemispheres 71.6
2093 Male, age 80, both hemispheres 64.6
2801 Male, age 74, both hemispheres 63.6
2743 Female, age 85, both hemispheres 63.2
2803 Female, age 91, both hemispheres 60.8
Motor facial nucleus
nTPM: 59.2
2795 Female, age 91, both hemispheres 71.8
2126 Male, age 61, both hemispheres 64.9
2365 Male, age 74, right hemisphere 60.4
2062 Male, age 76, both hemispheres 54.2
2697 Female, age 85, both hemispheres 53.2
2327 Male, age 80, both hemispheres 50.7
Motor hypoglossal nucleus
nTPM: 68.2
2461 Male, age 61, both hemispheres 83.2
2277 Male, age 76, both hemispheres 73.6
2125 Female, age 91, both hemispheres 69.7
2182 Male, age 80, both hemispheres 61.1
2132 Female, age 85, both hemispheres 53.6
Motor trigeminal nucleus
nTPM: 60.6
2309 Male, age 76, both hemispheres 66.7
2335 Male, age 61, both hemispheres 65.1
2079 Male, age 80, both hemispheres 58.4
2321 Female, age 91, both hemispheres 56.9
2560 Male, age 74, both hemispheres 56.0
Nuclei of the trapezoid body
nTPM: 61.2
2159 Male, age 61, both hemispheres 66.9
2368 Female, age 91, both hemispheres 66.0
2735 Female, age 85, both hemispheres 60.2
1983 Male, age 76, both hemispheres 57.5
2166 Male, age 80, both hemispheres 55.3
Nucleus ambiguus
nTPM: 74.9
2071 Male, age 76, both hemispheres 84.5
2096 Female, age 85, both hemispheres 65.2
Nucleus cuneatus
nTPM: 71.2
2100 Male, age 76, both hemispheres 79.5
2131 Male, age 76, both hemispheres 74.9
2562 Male, age 61, both hemispheres 74.3
2808 Female, age 85, both hemispheres 73.6
2380 Male, age 80, both hemispheres 72.7
2376 Male, age 61, both hemispheres 72.4
2564 Male, age 74, both hemispheres 71.5
2805 Female, age 91, both hemispheres 64.8
2381 Male, age 80, both hemispheres 57.5
Nucleus gracilis
nTPM: 65.7
2627 Male, age 74, both hemispheres 68.7
2299 Female, age 85, both hemispheres 65.8
2382 Male, age 80, both hemispheres 62.6
Nucleus raphe magnus
nTPM: 58.5
2051 Male, age 76, both hemispheres 66.7
2160 Male, age 61, both hemispheres 61.6
2455 Male, age 74, both hemispheres 58.5
2459 Female, age 91, both hemispheres 57.4
2328 Male, age 80, both hemispheres 54.8
2172 Female, age 85, both hemispheres 51.7
Nucleus raphe obscurus
nTPM: 74.4
2142 Male, age 76, midline 95.4
2800 Male, age 61, midline 67.0
2845 Female, age 85, midline 61.0
Nucleus raphe pallidus
nTPM: 83.9
1924 Male, age 61, midline 92.4
2145 Male, age 76, midline 89.1
2183 Male, age 80, midline 70.1
Nucleus tractus solitarii
nTPM: 68.2
2191 Female, age 85, both hemispheres 76.9
2144 Female, age 91, right hemisphere 71.3
2656 Male, age 76, both hemispheres 66.0
2307 Male, age 80, both hemispheres 58.4
Paramedian reticular nucleus
nTPM: 64.4
2057 Male, age 80, both hemispheres 70.7
2313 Male, age 61, both hemispheres 65.1
2052 Male, age 76, both hemispheres 64.7
2050 Female, age 85, both hemispheres 57.0
Parvicellular reticular nuclei
nTPM: 65.4
2119 Male, age 80, both hemispheres 77.4
2095 Male, age 76, both hemispheres 65.9
2558 Male, age 74, both hemispheres 52.7
Parvicellular reticular nuclei, medullary
nTPM: 61.5
2091 Female, age 85, both hemispheres 70.2
2189 Female, age 91, both hemispheres 62.3
2181 Male, age 80, left hemisphere 52.1
Pedunculopontine tegmental nucleus
nTPM: 66.0
2338 Male, age 61, both hemispheres 72.0
1921 Female, age 85, both hemispheres 63.9
2334 Male, age 80, both hemispheres 62.1
Peritrigeminal nucleus
nTPM: 73.7
2136 Male, age 76, both hemispheres 77.3
2067 Female, age 85, both hemispheres 74.6
2179 Male, age 61, both hemispheres 69.1
Pontine nuclei
nTPM: 62.9
1863 Male, age 55, unknown 75.6
2109 Female, age 72, unknown 69.2
2115 Male, age 80, left hemisphere 68.6
2727 Male, age 61, right hemisphere 65.5
1968 Male, age 76, left hemisphere 57.4
2454 Male, age 74, left hemisphere 55.9
2787 Female, age 85, both hemispheres 55.9
2319 Female, age 91, both hemispheres 54.8
Pontine raphe nucleus
nTPM: 55.5
2853 Male, age 76, midline 59.4
2122 Female, age 85, midline 51.6
Posteroventral cochlear nucleus
nTPM: 63.7
2341 Male, age 80, both hemispheres 66.9
2371 Male, age 61, both hemispheres 66.6
2070 Male, age 76, both hemispheres 66.0
2135 Female, age 91, both hemispheres 59.6
2752 Female, age 85, both hemispheres 59.5
Prepositus hypoglossal nucleus
nTPM: 70.2
2855 Female, age 85, right hemisphere 72.4
2086 Male, age 80, both hemispheres 68.1
Principal sensory trigeminal nucleus
nTPM: 64.5
2324 Male, age 76, both hemispheres 84.4
2158 Male, age 61, both hemispheres 63.8
2367 Female, age 91, left hemisphere 55.3
2008 Male, age 80, left hemisphere 54.6
Reticular pontine nucleus, caudal
nTPM: 60.4
2092 Male, age 76, both hemispheres 64.8
2457 Female, age 91, both hemispheres 63.8
2559 Male, age 74, both hemispheres 57.6
2332 Male, age 80, right hemisphere 55.4
Reticular pontine nucleus, oral
nTPM: 61.9
1939 Male, age 80, both hemispheres 73.3
2167 Male, age 76, both hemispheres 64.6
2012 Female, age 85, both hemispheres 61.3
2366 Female, age 91, both hemispheres 57.3
2361 Male, age 74, both hemispheres 53.2
Reticulotegmental nucleus
nTPM: 59.3
2333 Male, age 80, both hemispheres 65.5
2322 Female, age 91, both hemispheres 60.6
2452 Male, age 74, both hemispheres 57.7
2325 Male, age 76, both hemispheres 53.5
Spinal trigeminal nucleus, caudal
nTPM: 66.4
2447 Male, age 76, both hemispheres 73.5
2390 Female, age 91, both hemispheres 68.2
2312 Male, age 61, both hemispheres 66.6
2308 Male, age 80, both hemispheres 64.2
2642 Male, age 74, both hemispheres 59.2
Spinal trigeminal nucleus, interpolar
nTPM: 72.1
2625 Male, age 61, both hemispheres 117.9
2033 Male, age 80, both hemispheres 67.7
2066 Male, age 76, right hemisphere 64.1
2386 Female, age 85, both hemispheres 55.9
2389 Female, age 91, both hemispheres 55.1
Spinal trigeminal nucleus, oral
nTPM: 67.6
2737 Female, age 85, both hemispheres 73.7
2164 Male, age 80, both hemispheres 68.8
1978 Male, age 76, both hemispheres 60.3
Spinal vestibular nucleus
nTPM: 61.1
2748 Male, age 76, both hemispheres 67.5
2796 Male, age 61, both hemispheres 63.1
2780 Male, age 80, both hemispheres 62.7
2186 Female, age 91, both hemispheres 60.1
2384 Male, age 74, both hemispheres 58.3
2806 Female, age 85, both hemispheres 54.9
Subcoeruleus area
nTPM: 60.4
2369 Female, age 85, left hemisphere 69.2
1958 Male, age 80, both hemispheres 62.4
2089 Male, age 76, left hemisphere 58.8
2451 Male, age 74, both hemispheres 56.8
2323 Female, age 91, left hemisphere 55.0
Superior olive
nTPM: 57.6
2364 Male, age 74, right hemisphere 65.1
2020 Male, age 76, both hemispheres 60.8
2329 Male, age 80, right hemisphere 54.8
1875 Female, age 85, both hemispheres 54.1
2561 Female, age 91, both hemispheres 53.0
Superior vestibular nucleus
nTPM: 75.1
2061 Male, age 76, both hemispheres 76.8
2383 Male, age 74, both hemispheres 75.8
2015 Male, age 80, both hemispheres 72.6
Ventral medullary reticular nucleus
nTPM: 71.8
2372 Male, age 61, both hemispheres 72.4
2060 Male, age 76, both hemispheres 71.2
Ventral periolivary nuclei
nTPM: 56.3
2130 Female, age 85, both hemispheres 60.2
2165 Male, age 80, both hemispheres 59.1
2023 Male, age 76, both hemispheres 57.2
2794 Female, age 91, left hemisphere 48.9
Ventrolateral medulla, A1-C1 cell groups
nTPM: 69.4
1986 Male, age 76, both hemispheres 75.6
2302 Female, age 91, both hemispheres 72.6
2741 Female, age 85, both hemispheres 67.6
2180 Male, age 61, both hemispheres 67.3
2118 Male, age 80, both hemispheres 63.7
Ventrolateral tegmental area, A5 NE cell group
nTPM: 61.9
2359 Male, age 61, both hemispheres 66.8
2840 Female, age 85, both hemispheres 65.0
2456 Female, age 91, both hemispheres 61.5
2161 Male, age 80, both hemispheres 60.2
2449 Male, age 74, both hemispheres 59.9
1959 Male, age 76, both hemispheres 58.2

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

123.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 123.2
FF:10182-103D2 60 years, female 124.2
FF:10165-103B3 76 years, female 122.3
Medulla oblongata
Scaled Tags Per Million: 115.5
FF:10155-103A2 76 years, female 140.8
FF:10038-101F2 18-64 years, mixed 103.0
FF:10174-103C3 60 years, female 102.7
Pons
Scaled Tags Per Million: 70.6
FF:10033-101E6 18-54 years, mixed 70.6

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

79.1
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 79.1
Samples: 4

Max nTPM: 88.1
Min nTPM: 69.5
Sample A Female 77.3
Sample B Female 69.5
Sample C Male 81.4
Sample D Male 88.1
Pons
nTPM: 60.0
Samples: 4

Max nTPM: 74.7
Min nTPM: 45.2
Sample A Female 61.5
Sample B Female 45.2
Sample C Male 58.4
Sample D Male 74.7

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

64.8
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 64.8
Samples: 4

Max nTPM: 69.2
Min nTPM: 60.6
Sample A Male 60.6
Sample B Male 65.3
Sample C Female 64.0
Sample D Female 69.2

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.1
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 3.1
73817430 Antisense, RP_051101_01_A05, Mouse strain C57BL/6J (56 days, male) 3.5
77798987 Antisense, RP_070212_03_A11, Mouse strain C57BL/6J (56 days, male) 3.1
69540345 Antisense, RP_050426_01_E10, Mouse strain C57BL/6J (56 days, male) 2.6
Pons
Expression energy: 2.1
73817430 Antisense, RP_051101_01_A05, Mouse strain C57BL/6J (56 days, male) 2.6
77798987 Antisense, RP_070212_03_A11, Mouse strain C57BL/6J (56 days, male) 2.2
69540345 Antisense, RP_050426_01_E10, Mouse strain C57BL/6J (56 days, male) 1.5

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