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TMEM145
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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Mouse brain, Intensity
Medulla oblongatai

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

39.075
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

52.155
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA Brain:50.6 nTPM
FANTOM5:31.3 Scaled Tags Per Million
Pig:32.3 nTPM
Mouse:16.6 nTPM
Allen mouse:5.0 Expression energy

MEDULLA OBLONGATA - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

, antibody HPA060462
Medulla oblongata mean intensity 39.075
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

FRONT BACK
Nucleus of the solitary tract 32.590
Raphe magnus nucleus 8.282
Cochlear nucleus 39.075
Lateral paragigantocellular nucleus 26.609
Raphe pallidus nucleus 7.925
Facial nucleus 14.576
Hypoglossal nucleus 31.585
Ambiguus nucleus 24.182
External cuneate nucleus 14.329
Inferior olivary nucleus 24.417
Raphe obscures nucleus 23.171
Dorsal motor nucleus of vagus 28.707
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 21.557
Parabrachial nucleus 52.155
Principle sensory trigeminal nucleus 17.469
Locus coeruleus 45.892
Pontine nucleus 25.885
Vestibular nucleus 13.465
Pontine reticular nucleus, oral 15.815
Lateral lemniscus 14.287
Superior paraolivary nucleus 12.149

PONS AND MEDULLA - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

50.6
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 45.5
1984 Male, age 76, both hemispheres 73.5
2301 Female, age 85, both hemispheres 40.5
2090 Male, age 80, both hemispheres 34.9
2188 Female, age 91, both hemispheres 33.1
Area postrema
nTPM: 28.9
2306 Male, age 80, both hemispheres 32.9
2054 Male, age 76, both hemispheres 32.2
2799 Male, age 61, both hemispheres 21.7
Dorsal cochlear nucleus
nTPM: 38.6
2370 Male, age 61, both hemispheres 48.6
2058 Male, age 76, both hemispheres 40.6
2378 Male, age 80, both hemispheres 37.0
2802 Male, age 74, right hemisphere 34.3
2187 Female, age 91, both hemispheres 32.5
Dorsal medullary reticular nucleus
nTPM: 40.7
2088 Male, age 76, both hemispheres 48.8
2373 Male, age 61, both hemispheres 41.2
2040 Female, age 85, both hemispheres 32.1
Dorsal motor vagal complex
nTPM: 38.8
2185 Male, age 76, both hemispheres 45.4
2807 Female, age 85, both hemispheres 42.1
2844 Male, age 55, unknown 41.7
2813 Female, age 72, unknown 40.7
2797 Male, age 61, both hemispheres 37.5
2643 Male, age 74, both hemispheres 35.6
2000 Male, age 74, unknown 33.8
2133 Female, age 91, both hemispheres 33.3
Dorsal tegmental nucleus
nTPM: 37.3
2358 Male, age 61, both hemispheres 42.6
2083 Male, age 80, both hemispheres 40.1
1936 Male, age 76, left hemisphere 36.7
2326 Male, age 74, both hemispheres 29.6
Dorsolateral tegmental area
nTPM: 36.7
2141 Male, age 76, both hemispheres 57.8
2654 Male, age 80, both hemispheres 34.6
2751 Female, age 85, both hemispheres 33.8
2337 Male, age 61, both hemispheres 28.9
2360 Male, age 74, both hemispheres 28.7
Gigantocellular reticular nuclei, medullary
nTPM: 42.8
2022 Male, age 76, right hemisphere 60.3
2310 Male, age 80, both hemispheres 54.3
2462 Male, age 74, both hemispheres 47.6
1876 Female, age 85, both hemispheres 38.7
2387 Female, age 91, both hemispheres 31.1
2314 Male, age 61, both hemispheres 25.0
Gigantocellular reticular nuclei, pars
nTPM: 46.0
2168 Male, age 76, both hemispheres 50.3
2706 Male, age 80, both hemispheres 47.8
2330 Male, age 80, both hemispheres 46.7
2084 Female, age 85, both hemispheres 42.6
2336 Male, age 61, both hemispheres 42.4
Inferior olive
nTPM: 27.8
2628 Female, age 91, both hemispheres 40.4
2563 Male, age 74, both hemispheres 27.8
2085 Female, age 85, both hemispheres 25.5
2178 Male, age 61, both hemispheres 23.3
2379 Male, age 80, both hemispheres 21.8
Kolliker-Fuse nucleus
nTPM: 35.0
2793 Female, age 91, left hemisphere 45.4
2163 Male, age 80, both hemispheres 34.8
2315 Male, age 76, right hemisphere 24.7
Lateral lemniscal nuclei
nTPM: 50.6
2320 Female, age 91, left hemisphere 56.2
2036 Male, age 80, both hemispheres 54.3
2453 Male, age 74, right hemisphere 50.0
2169 Male, age 76, both hemispheres 46.7
2746 Female, age 85, left hemisphere 45.8
Lateral medullary reticular nucleus
nTPM: 30.2
2044 Male, age 76, both hemispheres 39.3
2190 Female, age 85, both hemispheres 31.1
2374 Male, age 61, both hemispheres 29.0
2852 Male, age 80, both hemispheres 27.6
2804 Female, age 91, both hemispheres 27.1
2305 Male, age 74, both hemispheres 26.9
Lateral parabrachial nucleus
nTPM: 37.9
2139 Female, age 85, right hemisphere 48.7
2790 Male, age 61, both hemispheres 42.3
2013 Male, age 80, both hemispheres 38.7
2792 Male, age 76, both hemispheres 22.0
Lateral vestibular nucleus
nTPM: 39.9
2184 Male, age 76, both hemispheres 40.7
2311 Male, age 80, both hemispheres 39.1
Locus coeruleus
nTPM: 33.7
2720 Male, age 74, both hemispheres 41.4
2162 Male, age 80, both hemispheres 36.4
1980 Male, age 76, both hemispheres 34.5
2317 Female, age 72, unknown 32.7
2014 Male, age 55, unknown 31.4
2123 Female, age 91, both hemispheres 30.2
2788 Male, age 74, unknown 29.6
Medial olivary nucleus
nTPM: 24.1
2851 Male, age 80, both hemispheres 31.2
2138 Female, age 91, both hemispheres 23.5
1943 Male, age 61, both hemispheres 23.3
1962 Male, age 76, both hemispheres 18.5
Medial parabrachial nucleus
nTPM: 44.9
2463 Female, age 85, right hemisphere 50.1
2156 Male, age 61, both hemispheres 48.3
2786 Male, age 76, both hemispheres 44.9
2854 Male, age 80, both hemispheres 44.9
2170 Female, age 91, both hemispheres 36.5
Medial periolivary nuclei
nTPM: 43.4
2171 Female, age 85, both hemispheres 51.7
2458 Female, age 91, both hemispheres 46.0
2063 Male, age 76, both hemispheres 43.0
2791 Male, age 74, right hemisphere 41.8
2081 Male, age 80, both hemispheres 34.3
Medial vestibular nucleus
nTPM: 41.8
2093 Male, age 80, both hemispheres 56.0
2624 Male, age 61, both hemispheres 46.1
2803 Female, age 91, both hemispheres 43.0
2801 Male, age 74, both hemispheres 37.7
2743 Female, age 85, both hemispheres 35.8
2134 Male, age 76, both hemispheres 32.0
Motor facial nucleus
nTPM: 47.6
2327 Male, age 80, both hemispheres 67.1
2062 Male, age 76, both hemispheres 46.7
2697 Female, age 85, both hemispheres 45.9
2126 Male, age 61, both hemispheres 44.1
2365 Male, age 74, right hemisphere 43.3
2795 Female, age 91, both hemispheres 38.6
Motor hypoglossal nucleus
nTPM: 34.4
2132 Female, age 85, both hemispheres 37.4
2125 Female, age 91, both hemispheres 36.1
2461 Male, age 61, both hemispheres 34.8
2182 Male, age 80, both hemispheres 32.3
2277 Male, age 76, both hemispheres 31.2
Motor trigeminal nucleus
nTPM: 46.4
2079 Male, age 80, both hemispheres 50.5
2335 Male, age 61, both hemispheres 49.6
2321 Female, age 91, both hemispheres 49.2
2560 Male, age 74, both hemispheres 43.9
2309 Male, age 76, both hemispheres 38.7
Nuclei of the trapezoid body
nTPM: 47.5
2735 Female, age 85, both hemispheres 51.9
2159 Male, age 61, both hemispheres 50.9
2166 Male, age 80, both hemispheres 47.8
2368 Female, age 91, both hemispheres 47.0
1983 Male, age 76, both hemispheres 40.0
Nucleus ambiguus
nTPM: 41.6
2096 Female, age 85, both hemispheres 66.6
2071 Male, age 76, both hemispheres 16.6
Nucleus cuneatus
nTPM: 47.1
2131 Male, age 76, both hemispheres 63.9
2100 Male, age 76, both hemispheres 61.3
2381 Male, age 80, both hemispheres 50.1
2562 Male, age 61, both hemispheres 48.4
2805 Female, age 91, both hemispheres 48.4
2564 Male, age 74, both hemispheres 42.0
2808 Female, age 85, both hemispheres 40.9
2376 Male, age 61, both hemispheres 36.6
2380 Male, age 80, both hemispheres 32.4
Nucleus gracilis
nTPM: 33.1
2299 Female, age 85, both hemispheres 37.3
2382 Male, age 80, both hemispheres 35.3
2627 Male, age 74, both hemispheres 26.7
Nucleus raphe magnus
nTPM: 50.4
2172 Female, age 85, both hemispheres 64.2
2160 Male, age 61, both hemispheres 53.7
2328 Male, age 80, both hemispheres 51.4
2455 Male, age 74, both hemispheres 51.4
2459 Female, age 91, both hemispheres 44.8
2051 Male, age 76, both hemispheres 37.1
Nucleus raphe obscurus
nTPM: 27.3
2800 Male, age 61, midline 33.7
2845 Female, age 85, midline 25.4
2142 Male, age 76, midline 22.8
Nucleus raphe pallidus
nTPM: 26.2
2183 Male, age 80, midline 30.2
1924 Male, age 61, midline 25.1
2145 Male, age 76, midline 23.1
Nucleus tractus solitarii
nTPM: 35.1
2307 Male, age 80, both hemispheres 45.4
2656 Male, age 76, both hemispheres 41.8
2191 Female, age 85, both hemispheres 30.8
2144 Female, age 91, right hemisphere 22.3
Paramedian reticular nucleus
nTPM: 35.0
2050 Female, age 85, both hemispheres 43.1
2313 Male, age 61, both hemispheres 39.0
2057 Male, age 80, both hemispheres 33.6
2052 Male, age 76, both hemispheres 24.3
Parvicellular reticular nuclei
nTPM: 36.3
2558 Male, age 74, both hemispheres 50.1
2095 Male, age 76, both hemispheres 30.0
2119 Male, age 80, both hemispheres 28.8
Parvicellular reticular nuclei, medullary
nTPM: 45.1
2181 Male, age 80, left hemisphere 50.8
2091 Female, age 85, both hemispheres 43.4
2189 Female, age 91, both hemispheres 41.2
Pedunculopontine tegmental nucleus
nTPM: 37.6
1921 Female, age 85, both hemispheres 49.3
2334 Male, age 80, both hemispheres 35.6
2338 Male, age 61, both hemispheres 28.0
Peritrigeminal nucleus
nTPM: 36.0
2179 Male, age 61, both hemispheres 41.9
2067 Female, age 85, both hemispheres 37.3
2136 Male, age 76, both hemispheres 28.7
Pontine nuclei
nTPM: 42.1
2787 Female, age 85, both hemispheres 60.5
2115 Male, age 80, left hemisphere 46.6
1863 Male, age 55, unknown 41.3
1968 Male, age 76, left hemisphere 40.8
2727 Male, age 61, right hemisphere 38.9
2319 Female, age 91, both hemispheres 38.8
2109 Female, age 72, unknown 35.4
2454 Male, age 74, left hemisphere 34.7
Pontine raphe nucleus
nTPM: 41.7
2122 Female, age 85, midline 42.6
2853 Male, age 76, midline 40.9
Posteroventral cochlear nucleus
nTPM: 37.7
2752 Female, age 85, both hemispheres 46.5
2371 Male, age 61, both hemispheres 43.5
2070 Male, age 76, both hemispheres 36.2
2341 Male, age 80, both hemispheres 34.9
2135 Female, age 91, both hemispheres 27.4
Prepositus hypoglossal nucleus
nTPM: 43.6
2086 Male, age 80, both hemispheres 46.1
2855 Female, age 85, right hemisphere 41.0
Principal sensory trigeminal nucleus
nTPM: 45.9
2158 Male, age 61, both hemispheres 56.8
2008 Male, age 80, left hemisphere 47.3
2367 Female, age 91, left hemisphere 43.0
2324 Male, age 76, both hemispheres 36.3
Reticular pontine nucleus, caudal
nTPM: 42.4
2332 Male, age 80, right hemisphere 63.1
2559 Male, age 74, both hemispheres 36.3
2092 Male, age 76, both hemispheres 35.1
2457 Female, age 91, both hemispheres 35.0
Reticular pontine nucleus, oral
nTPM: 41.3
2012 Female, age 85, both hemispheres 45.1
2361 Male, age 74, both hemispheres 42.6
2167 Male, age 76, both hemispheres 42.4
2366 Female, age 91, both hemispheres 41.1
1939 Male, age 80, both hemispheres 35.3
Reticulotegmental nucleus
nTPM: 40.9
2333 Male, age 80, both hemispheres 44.6
2325 Male, age 76, both hemispheres 42.2
2452 Male, age 74, both hemispheres 41.0
2322 Female, age 91, both hemispheres 35.9
Spinal trigeminal nucleus, caudal
nTPM: 46.9
2447 Male, age 76, both hemispheres 57.5
2642 Male, age 74, both hemispheres 55.0
2308 Male, age 80, both hemispheres 48.3
2312 Male, age 61, both hemispheres 41.7
2390 Female, age 91, both hemispheres 32.1
Spinal trigeminal nucleus, interpolar
nTPM: 40.2
2386 Female, age 85, both hemispheres 46.1
2066 Male, age 76, right hemisphere 43.0
2389 Female, age 91, both hemispheres 41.1
2033 Male, age 80, both hemispheres 36.4
2625 Male, age 61, both hemispheres 34.7
Spinal trigeminal nucleus, oral
nTPM: 49.2
2737 Female, age 85, both hemispheres 61.3
2164 Male, age 80, both hemispheres 45.7
1978 Male, age 76, both hemispheres 40.5
Spinal vestibular nucleus
nTPM: 40.6
2796 Male, age 61, both hemispheres 48.7
2186 Female, age 91, both hemispheres 43.5
2806 Female, age 85, both hemispheres 42.3
2780 Male, age 80, both hemispheres 40.0
2748 Male, age 76, both hemispheres 35.7
2384 Male, age 74, both hemispheres 33.7
Subcoeruleus area
nTPM: 40.9
2089 Male, age 76, left hemisphere 48.9
2323 Female, age 91, left hemisphere 47.7
1958 Male, age 80, both hemispheres 43.3
2451 Male, age 74, both hemispheres 37.1
2369 Female, age 85, left hemisphere 27.5
Superior olive
nTPM: 46.1
2561 Female, age 91, both hemispheres 54.3
2329 Male, age 80, right hemisphere 50.9
1875 Female, age 85, both hemispheres 50.5
2364 Male, age 74, right hemisphere 39.3
2020 Male, age 76, both hemispheres 35.7
Superior vestibular nucleus
nTPM: 31.0
2015 Male, age 80, both hemispheres 35.0
2061 Male, age 76, both hemispheres 33.8
2383 Male, age 74, both hemispheres 24.1
Ventral medullary reticular nucleus
nTPM: 31.3
2060 Male, age 76, both hemispheres 36.6
2372 Male, age 61, both hemispheres 26.0
Ventral periolivary nuclei
nTPM: 49.5
2130 Female, age 85, both hemispheres 59.7
2794 Female, age 91, left hemisphere 54.8
2165 Male, age 80, both hemispheres 50.3
2023 Male, age 76, both hemispheres 33.1
Ventrolateral medulla, A1-C1 cell groups
nTPM: 33.5
2741 Female, age 85, both hemispheres 39.8
1986 Male, age 76, both hemispheres 36.8
2302 Female, age 91, both hemispheres 36.2
2180 Male, age 61, both hemispheres 29.5
2118 Male, age 80, both hemispheres 25.4
Ventrolateral tegmental area, A5 NE cell group
nTPM: 42.4
2840 Female, age 85, both hemispheres 46.3
2449 Male, age 74, both hemispheres 45.3
1959 Male, age 76, both hemispheres 45.1
2456 Female, age 91, both hemispheres 44.2
2161 Male, age 80, both hemispheres 43.8
2359 Male, age 61, both hemispheres 30.0

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

31.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 18.9
FF:10182-103D2 60 years, female 20.0
FF:10165-103B3 76 years, female 17.8
Medulla oblongata
Scaled Tags Per Million: 16.0
FF:10155-103A2 76 years, female 20.3
FF:10038-101F2 18-64 years, mixed 17.0
FF:10174-103C3 60 years, female 10.7
Pons
Scaled Tags Per Million: 31.3
FF:10033-101E6 18-54 years, mixed 31.3

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

32.3
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 24.5
Samples: 4

Max nTPM: 27.7
Min nTPM: 19.0
Sample A Female 27.7
Sample B Female 27.4
Sample C Male 23.9
Sample D Male 19.0
Pons
nTPM: 32.4
Samples: 4

Max nTPM: 49.8
Min nTPM: 23.6
Sample A Female 49.8
Sample B Female 25.5
Sample C Male 23.6
Sample D Male 30.5

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

16.6
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 16.5
Samples: 4

Max nTPM: 18.6
Min nTPM: 14.1
Sample A Male 18.0
Sample B Male 15.4
Sample C Female 18.6
Sample D Female 14.1

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

5.0
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 4.7
70305478 Antisense, RP_050609_04_C06, Mouse strain C57BL/6J (56 days, male) 5.4
74511987 Antisense, RP_060220_03_C12, Mouse strain C57BL/6J (56 days, male) 4.1
Pons
Expression energy: 5.0
70305478 Antisense, RP_050609_04_C06, Mouse strain C57BL/6J (56 days, male) 5.6
74511987 Antisense, RP_060220_03_C12, Mouse strain C57BL/6J (56 days, male) 4.4

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