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PTP4A2
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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA Brain:396.2 nTPM
FANTOM5:276.3 Scaled Tags Per Million
Pig:198.7 nTPM
Mouse:91.3 nTPM
Allen mouse:0.7 Expression energy

PONS AND MEDULLA - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

396.2
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 343.7
2301 Female, age 85, both hemispheres 457.2
2188 Female, age 91, both hemispheres 398.4
2090 Male, age 80, both hemispheres 329.6
1984 Male, age 76, both hemispheres 189.6
Area postrema
nTPM: 380.1
2799 Male, age 61, both hemispheres 500.0
2306 Male, age 80, both hemispheres 373.4
2054 Male, age 76, both hemispheres 267.0
Dorsal cochlear nucleus
nTPM: 364.3
2802 Male, age 74, right hemisphere 433.8
2378 Male, age 80, both hemispheres 387.4
2187 Female, age 91, both hemispheres 340.5
2370 Male, age 61, both hemispheres 334.0
2058 Male, age 76, both hemispheres 325.8
Dorsal medullary reticular nucleus
nTPM: 328.2
2373 Male, age 61, both hemispheres 345.3
2040 Female, age 85, both hemispheres 332.5
2088 Male, age 76, both hemispheres 306.9
Dorsal motor vagal complex
nTPM: 330.6
2797 Male, age 61, both hemispheres 577.3
2807 Female, age 85, both hemispheres 378.0
2185 Male, age 76, both hemispheres 373.6
2643 Male, age 74, both hemispheres 325.6
2133 Female, age 91, both hemispheres 278.9
2000 Male, age 74, unknown 257.5
2813 Female, age 72, unknown 250.0
2844 Male, age 55, unknown 204.3
Dorsal tegmental nucleus
nTPM: 329.8
2326 Male, age 74, both hemispheres 397.6
2083 Male, age 80, both hemispheres 333.1
1936 Male, age 76, left hemisphere 300.7
2358 Male, age 61, both hemispheres 287.9
Dorsolateral tegmental area
nTPM: 307.2
2654 Male, age 80, both hemispheres 369.9
2751 Female, age 85, both hemispheres 356.8
2337 Male, age 61, both hemispheres 325.7
2360 Male, age 74, both hemispheres 263.9
2141 Male, age 76, both hemispheres 219.9
Gigantocellular reticular nuclei, medullary
nTPM: 340.4
2387 Female, age 91, both hemispheres 438.4
2314 Male, age 61, both hemispheres 387.0
2310 Male, age 80, both hemispheres 345.6
2022 Male, age 76, right hemisphere 315.2
1876 Female, age 85, both hemispheres 314.9
2462 Male, age 74, both hemispheres 241.4
Gigantocellular reticular nuclei, pars
nTPM: 304.0
2330 Male, age 80, both hemispheres 348.5
2336 Male, age 61, both hemispheres 315.7
2084 Female, age 85, both hemispheres 310.2
2706 Male, age 80, both hemispheres 306.7
2168 Male, age 76, both hemispheres 238.6
Inferior olive
nTPM: 316.6
2379 Male, age 80, both hemispheres 360.2
2628 Female, age 91, both hemispheres 333.4
2085 Female, age 85, both hemispheres 323.7
2178 Male, age 61, both hemispheres 312.9
2563 Male, age 74, both hemispheres 252.6
Kolliker-Fuse nucleus
nTPM: 320.2
2793 Female, age 91, left hemisphere 372.0
2163 Male, age 80, both hemispheres 312.8
2315 Male, age 76, right hemisphere 275.7
Lateral lemniscal nuclei
nTPM: 316.0
2320 Female, age 91, left hemisphere 366.5
2036 Male, age 80, both hemispheres 346.2
2453 Male, age 74, right hemisphere 320.6
2169 Male, age 76, both hemispheres 287.8
2746 Female, age 85, left hemisphere 259.0
Lateral medullary reticular nucleus
nTPM: 306.0
2190 Female, age 85, both hemispheres 349.8
2374 Male, age 61, both hemispheres 323.4
2804 Female, age 91, both hemispheres 307.8
2044 Male, age 76, both hemispheres 304.2
2305 Male, age 74, both hemispheres 288.1
2852 Male, age 80, both hemispheres 262.4
Lateral parabrachial nucleus
nTPM: 336.5
2792 Male, age 76, both hemispheres 442.9
2013 Male, age 80, both hemispheres 356.5
2790 Male, age 61, both hemispheres 315.2
2139 Female, age 85, right hemisphere 231.3
Lateral vestibular nucleus
nTPM: 321.3
2311 Male, age 80, both hemispheres 352.5
2184 Male, age 76, both hemispheres 290.1
Locus coeruleus
nTPM: 235.1
2720 Male, age 74, both hemispheres 333.3
2162 Male, age 80, both hemispheres 280.6
2014 Male, age 55, unknown 223.0
2317 Female, age 72, unknown 221.8
2788 Male, age 74, unknown 220.4
1980 Male, age 76, both hemispheres 186.7
2123 Female, age 91, both hemispheres 180.3
Medial olivary nucleus
nTPM: 367.6
1962 Male, age 76, both hemispheres 389.5
1943 Male, age 61, both hemispheres 388.0
2851 Male, age 80, both hemispheres 347.9
2138 Female, age 91, both hemispheres 344.8
Medial parabrachial nucleus
nTPM: 307.3
2854 Male, age 80, both hemispheres 329.8
2170 Female, age 91, both hemispheres 325.7
2786 Male, age 76, both hemispheres 311.3
2156 Male, age 61, both hemispheres 303.9
2463 Female, age 85, right hemisphere 265.9
Medial periolivary nuclei
nTPM: 296.0
2458 Female, age 91, both hemispheres 371.2
2081 Male, age 80, both hemispheres 353.9
2063 Male, age 76, both hemispheres 279.7
2171 Female, age 85, both hemispheres 237.5
2791 Male, age 74, right hemisphere 237.5
Medial vestibular nucleus
nTPM: 269.8
2803 Female, age 91, both hemispheres 376.1
2093 Male, age 80, both hemispheres 311.0
2624 Male, age 61, both hemispheres 286.6
2801 Male, age 74, both hemispheres 236.4
2134 Male, age 76, both hemispheres 207.4
2743 Female, age 85, both hemispheres 201.6
Motor facial nucleus
nTPM: 311.2
2697 Female, age 85, both hemispheres 391.2
2327 Male, age 80, both hemispheres 340.0
2795 Female, age 91, both hemispheres 331.0
2126 Male, age 61, both hemispheres 293.3
2365 Male, age 74, right hemisphere 271.1
2062 Male, age 76, both hemispheres 240.9
Motor hypoglossal nucleus
nTPM: 308.1
2132 Female, age 85, both hemispheres 373.4
2182 Male, age 80, both hemispheres 352.0
2461 Male, age 61, both hemispheres 310.1
2125 Female, age 91, both hemispheres 299.2
2277 Male, age 76, both hemispheres 205.8
Motor trigeminal nucleus
nTPM: 316.2
2321 Female, age 91, both hemispheres 356.2
2309 Male, age 76, both hemispheres 330.5
2335 Male, age 61, both hemispheres 311.2
2560 Male, age 74, both hemispheres 303.2
2079 Male, age 80, both hemispheres 280.1
Nuclei of the trapezoid body
nTPM: 292.7
2368 Female, age 91, both hemispheres 345.6
2166 Male, age 80, both hemispheres 328.1
2159 Male, age 61, both hemispheres 293.6
1983 Male, age 76, both hemispheres 272.1
2735 Female, age 85, both hemispheres 224.0
Nucleus ambiguus
nTPM: 269.6
2071 Male, age 76, both hemispheres 374.1
2096 Female, age 85, both hemispheres 165.1
Nucleus cuneatus
nTPM: 345.2
2805 Female, age 91, both hemispheres 426.5
2380 Male, age 80, both hemispheres 425.9
2808 Female, age 85, both hemispheres 417.5
2381 Male, age 80, both hemispheres 364.3
2376 Male, age 61, both hemispheres 354.6
2562 Male, age 61, both hemispheres 316.7
2564 Male, age 74, both hemispheres 308.0
2100 Male, age 76, both hemispheres 271.2
2131 Male, age 76, both hemispheres 222.6
Nucleus gracilis
nTPM: 389.8
2299 Female, age 85, both hemispheres 437.2
2382 Male, age 80, both hemispheres 424.7
2627 Male, age 74, both hemispheres 307.6
Nucleus raphe magnus
nTPM: 292.5
2459 Female, age 91, both hemispheres 376.9
2328 Male, age 80, both hemispheres 345.8
2051 Male, age 76, both hemispheres 336.1
2455 Male, age 74, both hemispheres 256.5
2160 Male, age 61, both hemispheres 222.7
2172 Female, age 85, both hemispheres 216.7
Nucleus raphe obscurus
nTPM: 363.2
2142 Male, age 76, midline 391.5
2845 Female, age 85, midline 378.1
2800 Male, age 61, midline 319.9
Nucleus raphe pallidus
nTPM: 338.0
2145 Male, age 76, midline 409.1
1924 Male, age 61, midline 322.2
2183 Male, age 80, midline 282.6
Nucleus tractus solitarii
nTPM: 229.4
2191 Female, age 85, both hemispheres 249.6
2144 Female, age 91, right hemisphere 230.3
2656 Male, age 76, both hemispheres 227.8
2307 Male, age 80, both hemispheres 209.8
Paramedian reticular nucleus
nTPM: 340.8
2052 Male, age 76, both hemispheres 443.5
2313 Male, age 61, both hemispheres 329.5
2057 Male, age 80, both hemispheres 301.1
2050 Female, age 85, both hemispheres 289.1
Parvicellular reticular nuclei
nTPM: 307.1
2095 Male, age 76, both hemispheres 335.7
2119 Male, age 80, both hemispheres 300.6
2558 Male, age 74, both hemispheres 285.1
Parvicellular reticular nuclei, medullary
nTPM: 294.4
2181 Male, age 80, left hemisphere 313.6
2189 Female, age 91, both hemispheres 304.1
2091 Female, age 85, both hemispheres 265.6
Pedunculopontine tegmental nucleus
nTPM: 341.4
2334 Male, age 80, both hemispheres 378.6
2338 Male, age 61, both hemispheres 371.4
1921 Female, age 85, both hemispheres 274.1
Peritrigeminal nucleus
nTPM: 278.0
2136 Male, age 76, both hemispheres 315.5
2179 Male, age 61, both hemispheres 281.1
2067 Female, age 85, both hemispheres 237.4
Pontine nuclei
nTPM: 315.8
2319 Female, age 91, both hemispheres 443.6
2454 Male, age 74, left hemisphere 382.5
2115 Male, age 80, left hemisphere 317.6
1968 Male, age 76, left hemisphere 311.3
1863 Male, age 55, unknown 307.8
2109 Female, age 72, unknown 292.4
2727 Male, age 61, right hemisphere 274.1
2787 Female, age 85, both hemispheres 196.8
Pontine raphe nucleus
nTPM: 276.5
2122 Female, age 85, midline 303.3
2853 Male, age 76, midline 249.7
Posteroventral cochlear nucleus
nTPM: 396.2
2341 Male, age 80, both hemispheres 476.3
2135 Female, age 91, both hemispheres 455.2
2371 Male, age 61, both hemispheres 432.7
2070 Male, age 76, both hemispheres 311.0
2752 Female, age 85, both hemispheres 306.0
Prepositus hypoglossal nucleus
nTPM: 258.4
2855 Female, age 85, right hemisphere 308.3
2086 Male, age 80, both hemispheres 208.5
Principal sensory trigeminal nucleus
nTPM: 284.7
2367 Female, age 91, left hemisphere 361.6
2324 Male, age 76, both hemispheres 309.0
2008 Male, age 80, left hemisphere 236.0
2158 Male, age 61, both hemispheres 232.3
Reticular pontine nucleus, caudal
nTPM: 348.0
2457 Female, age 91, both hemispheres 419.4
2559 Male, age 74, both hemispheres 354.9
2332 Male, age 80, right hemisphere 327.5
2092 Male, age 76, both hemispheres 290.1
Reticular pontine nucleus, oral
nTPM: 342.8
2366 Female, age 91, both hemispheres 459.1
1939 Male, age 80, both hemispheres 361.5
2167 Male, age 76, both hemispheres 329.1
2012 Female, age 85, both hemispheres 285.2
2361 Male, age 74, both hemispheres 278.9
Reticulotegmental nucleus
nTPM: 354.4
2452 Male, age 74, both hemispheres 407.6
2322 Female, age 91, both hemispheres 389.8
2333 Male, age 80, both hemispheres 356.2
2325 Male, age 76, both hemispheres 263.8
Spinal trigeminal nucleus, caudal
nTPM: 319.5
2312 Male, age 61, both hemispheres 381.3
2308 Male, age 80, both hemispheres 332.2
2390 Female, age 91, both hemispheres 311.0
2642 Male, age 74, both hemispheres 296.5
2447 Male, age 76, both hemispheres 276.7
Spinal trigeminal nucleus, interpolar
nTPM: 308.0
2389 Female, age 91, both hemispheres 357.1
2386 Female, age 85, both hemispheres 326.4
2033 Male, age 80, both hemispheres 322.2
2625 Male, age 61, both hemispheres 278.7
2066 Male, age 76, right hemisphere 255.3
Spinal trigeminal nucleus, oral
nTPM: 291.9
2164 Male, age 80, both hemispheres 337.2
1978 Male, age 76, both hemispheres 295.3
2737 Female, age 85, both hemispheres 243.4
Spinal vestibular nucleus
nTPM: 367.7
2384 Male, age 74, both hemispheres 484.0
2806 Female, age 85, both hemispheres 410.6
2796 Male, age 61, both hemispheres 354.8
2186 Female, age 91, both hemispheres 339.8
2748 Male, age 76, both hemispheres 315.6
2780 Male, age 80, both hemispheres 301.2
Subcoeruleus area
nTPM: 336.3
2369 Female, age 85, left hemisphere 409.4
2451 Male, age 74, both hemispheres 399.2
1958 Male, age 80, both hemispheres 307.2
2323 Female, age 91, left hemisphere 295.1
2089 Male, age 76, left hemisphere 270.5
Superior olive
nTPM: 314.0
2020 Male, age 76, both hemispheres 376.8
2329 Male, age 80, right hemisphere 339.3
2561 Female, age 91, both hemispheres 331.1
1875 Female, age 85, both hemispheres 265.4
2364 Male, age 74, right hemisphere 257.4
Superior vestibular nucleus
nTPM: 262.0
2015 Male, age 80, both hemispheres 300.3
2383 Male, age 74, both hemispheres 252.1
2061 Male, age 76, both hemispheres 233.4
Ventral medullary reticular nucleus
nTPM: 332.1
2372 Male, age 61, both hemispheres 373.5
2060 Male, age 76, both hemispheres 290.6
Ventral periolivary nuclei
nTPM: 292.6
2023 Male, age 76, both hemispheres 371.9
2794 Female, age 91, left hemisphere 300.1
2165 Male, age 80, both hemispheres 278.0
2130 Female, age 85, both hemispheres 220.2
Ventrolateral medulla, A1-C1 cell groups
nTPM: 308.3
2118 Male, age 80, both hemispheres 343.6
2302 Female, age 91, both hemispheres 341.1
1986 Male, age 76, both hemispheres 288.4
2180 Male, age 61, both hemispheres 287.0
2741 Female, age 85, both hemispheres 281.6
Ventrolateral tegmental area, A5 NE cell group
nTPM: 320.4
2456 Female, age 91, both hemispheres 364.4
2161 Male, age 80, both hemispheres 359.2
2840 Female, age 85, both hemispheres 335.4
2359 Male, age 61, both hemispheres 299.7
1959 Male, age 76, both hemispheres 297.1
2449 Male, age 74, both hemispheres 266.6

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

276.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 276.3
FF:10182-103D2 60 years, female 316.8
FF:10165-103B3 76 years, female 235.9
Medulla oblongata
Scaled Tags Per Million: 239.1
FF:10038-101F2 18-64 years, mixed 257.7
FF:10174-103C3 60 years, female 232.7
FF:10155-103A2 76 years, female 226.8
Pons
Scaled Tags Per Million: 276.2
FF:10033-101E6 18-54 years, mixed 276.2

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

198.7
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 192.4
Samples: 4

Max nTPM: 236.7
Min nTPM: 167.7
Sample A Female 236.7
Sample B Female 171.1
Sample C Male 194.0
Sample D Male 167.7
Pons
nTPM: 198.7
Samples: 4

Max nTPM: 226.4
Min nTPM: 172.9
Sample A Female 196.5
Sample B Female 172.9
Sample C Male 226.4
Sample D Male 198.9

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

91.3
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 91.3
Samples: 4

Max nTPM: 93.8
Min nTPM: 87.0
Sample A Male 87.0
Sample B Male 91.7
Sample C Female 92.8
Sample D Female 93.8

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.7
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 0.7
71280538 Antisense, RP_050818_01_A11, Mouse strain C57BL/6J (56 days, male) 1.4
77799059 Antisense, RP_070212_03_E04, Mouse strain C57BL/6J (56 days, male) 0.4
70813353 Antisense, RP_050712_03_G08, Mouse strain C57BL/6J (56 days, male) 0.3
Pons
Expression energy: 0.5
71280538 Antisense, RP_050818_01_A11, Mouse strain C57BL/6J (56 days, male) 0.9
77799059 Antisense, RP_070212_03_E04, Mouse strain C57BL/6J (56 days, male) 0.4
70813353 Antisense, RP_050712_03_G08, Mouse strain C57BL/6J (56 days, male) 0.2

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