Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA single nuclei brain specificity" "RNA single nuclei brain distribution" "RNA single nuclei brain specificity score" "RNA single nuclei brain specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)" "Cancer prognostics - Breast Invasive Carcinoma (TCGA)" "Cancer prognostics - Breast Invasive Carcinoma (validation)" "Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)" "Cancer prognostics - Colon Adenocarcinoma (TCGA)" "Cancer prognostics - Colon Adenocarcinoma (validation)" "Cancer prognostics - Glioblastoma Multiforme (TCGA)" "Cancer prognostics - Glioblastoma Multiforme (validation)" "Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)" "Cancer prognostics - Kidney Chromophobe (TCGA)" "Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)" "Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)" "Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)" "Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)" "Cancer prognostics - Liver Hepatocellular Carcinoma (validation)" "Cancer prognostics - Lung Adenocarcinoma (TCGA)" "Cancer prognostics - Lung Adenocarcinoma (validation)" "Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)" "Cancer prognostics - Lung Squamous Cell Carcinoma (validation)" "Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)" "Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)" "Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)" "Cancer prognostics - Pancreatic Adenocarcinoma (validation)" "Cancer prognostics - Prostate Adenocarcinoma (TCGA)" "Cancer prognostics - Rectum Adenocarcinoma (TCGA)" "Cancer prognostics - Rectum Adenocarcinoma (validation)" "Cancer prognostics - Skin Cuteneous Melanoma (TCGA)" "Cancer prognostics - Stomach Adenocarcinoma (TCGA)" "Cancer prognostics - Testicular Germ Cell Tumor (TCGA)" "Cancer prognostics - Thyroid Carcinoma (TCGA)" "Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)" ABHD12B "BEM46L3, C14orf29" ENSG00000131969 "Abhydrolase domain containing 12B" Q7Z5M8 14 50872053-50904970 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 6.6;retina: 13.9;skin 1: 10.1" "Cell type enriched" "Detected in some" 5 "Muller glia cells: 165.0" "Cell type enhanced" "Detected in many" "medium spiny neuron: 29.7;thalamic excitatory: 39.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 1.0;neutrophil: 2.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.2" "Cancer enriched" "Detected in some" 5 "cervical cancer: 5.6" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Skin - Keratinocyte (granular), Spleen - Neutrophils" "Region enriched" "Detected in single" 5 "thalamus: 2.1" "Low region specificity" "Detected in many" HPA002873 Uncertain Uncertain Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 38: Sub-cortical - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 10: Muller glia cells - Visual perception" Nucleoplasm "HPA002873: AB_2220573" "unprognostic (9.85e-2)" "unprognostic (7.12e-2)" "unprognostic (7.46e-2)" "unprognostic (7.74e-2)" "unprognostic (1.50e-2)" "unprognostic (1.40e-2)" "unprognostic (5.11e-2)" ADAM12 "MCMPMltna, MLTN" ENSG00000148848 "ADAM metallopeptidase domain 12" O43184 10 126012381-126388477 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 130.4" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 479.5" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 292.4" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 24.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 4.5" "Lineage enriched" "Detected in single" 45 "T-cells: 4.5" "Cancer enhanced" "Detected in many" "Brain cancer: 41.1;Kidney cancer: 31.8" "Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030866, HPA030867, HPA030868" Enhanced Supported "Plasma membrane" "Secreted in female reproductive system" "Cell adhesion" NA NA 12000000 "Cluster 1: T-cells - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" 10 "Plasma membrane" "HPA030866: AB_2673636, HPA030867: AB_10602428, HPA030868: AB_2673638" "unprognostic (5.38e-2)" "unprognostic (2.73e-1)" "unprognostic (1.02e-1)" "unprognostic (2.42e-3)" "unprognostic (1.13e-2)" "unprognostic (6.50e-2)" "unprognostic (8.50e-2)" "unprognostic (1.11e-3)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "validated prognostic unfavorable (2.02e-5)" "validated prognostic unfavorable (3.63e-5)" "potential prognostic unfavorable (6.38e-4)" "unprognostic (1.69e-3)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (2.04e-1)" "unprognostic (1.99e-1)" "unprognostic (4.71e-3)" "potential prognostic unfavorable (5.36e-5)" "unprognostic (4.10e-2)" "unprognostic (1.41e-1)" "unprognostic (9.85e-2)" "unprognostic (6.35e-3)" "unprognostic (9.98e-2)" "unprognostic (2.78e-3)" "unprognostic (2.52e-2)" "unprognostic (2.40e-3)" "unprognostic (6.36e-3)" ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 12.9;smooth muscle: 10.8" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 237.1" "Group enriched" "Detected in all" 4 "bergmann glia: 3673.3;deep-layer corticothalamic and 6b: 1246.3" "Group enriched" "Detected in many" 10 "Kidney Chromophobe (TCGA): 21.7;Prostate Adenocarcinoma (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 15.5;Sarcoma: 18.9" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" Enzyme NA NA 30000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (1.66e-1)" "unprognostic (2.08e-2)" "unprognostic (1.19e-1)" "unprognostic (2.09e-1)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (1.44e-2)" "unprognostic (4.18e-3)" "unprognostic (1.06e-1)" "unprognostic (2.83e-3)" "unprognostic (2.41e-2)" "potential prognostic favorable (1.74e-4)" "potential prognostic unfavorable (1.23e-5)" "unprognostic (8.09e-2)" "unprognostic (9.43e-2)" "unprognostic (7.19e-2)" "unprognostic (3.45e-2)" "unprognostic (7.73e-3)" "unprognostic (1.82e-1)" "unprognostic (1.38e-1)" ADCY8 "AC8, ADCY3, HBAC1" ENSG00000155897 "Adenylate cyclase 8" P40145 8 130780301-131040909 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.1;epididymis: 22.3" "Group enriched" "Detected in some" 5 "Astrocytes: 144.0;Inhibitory neurons: 241.0;Oligodendrocyte precursor cells: 130.2" "Cell type enhanced" "Detected in all" "astrocyte: 652.9" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.2;Rhabdoid: 1.1" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018652, HPA024291" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 8: Neurons - Neuronal signaling" 1 "Plasma membrane, Cytosol" Nucleoplasm "CAB018652: AB_633654, HPA024291: AB_1844597" "unprognostic (1.28e-1)" "unprognostic (1.91e-1)" "potential prognostic favorable (7.23e-4)" "unprognostic (3.06e-2)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (8.51e-2)" "unprognostic (2.01e-1)" "unprognostic (3.52e-2)" "unprognostic (9.63e-2)" ADGRA1 "GPR123, KIAA1828" ENSG00000197177 "Adhesion G protein-coupled receptor A1" Q86SQ6 10 133087924-133131675 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 26.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 24.4;Horizontal cells: 23.9;Inhibitory neurons: 23.6;Oligodendrocyte precursor cells: 27.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 8.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bone cancer: 6.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042773 Approved NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" "HPA042773: AB_10794764" "unprognostic (2.16e-1)" "potential prognostic favorable (1.12e-4)" "unprognostic (9.86e-2)" ADGRD1 "DKFZp434B1272, GPR133, PGR25" ENSG00000111452 "Adhesion G protein-coupled receptor D1" Q6QNK2 12 130953907-131141469 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 60.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 28.1;Cardiomyocytes: 34.0;Endometrial stromal cells: 45.9;Fibroblasts: 31.6;Mesothelial cells: 75.6;Microglial cells: 24.2;Sertoli cells: 32.6" "Cell type enhanced" "Detected in many" "fibroblast: 194.7;pericyte: 161.1" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 11.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.0;intermediate monocyte: 2.3;myeloid DC: 1.1;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;monocytes: 2.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Pituitary gland - Fibroblasts, Spleen - Fibroblast_1" "Region enhanced" "Detected in some" "basal ganglia: 5.1" "Low region specificity" "Detected in all" "HPA042395, HPA076279" Uncertain Approved "Nucleoplasm,Nuclear speckles,Plasma membrane" NA NA 890000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "Plasma membrane" "Nucleoplasm, Nuclear speckles" "HPA042395: AB_10796906, HPA076279: " "unprognostic (1.33e-1)" "unprognostic (9.78e-2)" "unprognostic (4.33e-2)" "unprognostic (4.17e-2)" "unprognostic (8.47e-3)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (6.49e-5)" "potential prognostic favorable (3.40e-4)" "unprognostic (2.75e-2)" "unprognostic (4.86e-3)" "unprognostic (2.19e-1)" "unprognostic (1.35e-1)" "unprognostic (4.84e-2)" "unprognostic (8.06e-2)" "unprognostic (1.01e-1)" "unprognostic (4.72e-2)" "unprognostic (4.16e-3)" "unprognostic (1.47e-2)" "unprognostic (1.14e-2)" "unprognostic (1.89e-1)" "unprognostic (4.53e-2)" "unprognostic (1.36e-1)" ADGRG6 "FLJ14937, GPR126" ENSG00000112414 "Adhesion G protein-coupled receptor G6" Q86SQ4 6 142301854-142446266 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 69.7;placenta: 45.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 110.5;Suprabasal keratinocytes: 40.4" "Cell type enhanced" "Detected in many" "endothelial cell: 268.7;LAMP5-LHX6 and Chandelier: 70.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Macrophages, Colon - Enteric glia cells, Skin - Keratinocyte (other), Spleen - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017346 Approved NA NA 60000000 "Cluster 11: Liver - Plasma proteins" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Hepatocytes - Metabolism" "HPA017346: AB_1849260" "unprognostic (1.05e-1)" "unprognostic (1.48e-2)" "unprognostic (5.77e-3)" "unprognostic (3.99e-2)" "unprognostic (5.93e-3)" "unprognostic (1.79e-3)" "unprognostic (5.31e-2)" "unprognostic (2.54e-1)" "unprognostic (3.96e-1)" "potential prognostic favorable (9.25e-4)" "unprognostic (2.96e-2)" "unprognostic (9.15e-2)" "unprognostic (1.68e-1)" "unprognostic (3.99e-3)" "unprognostic (4.81e-1)" "unprognostic (1.14e-2)" "unprognostic (4.11e-1)" "unprognostic (7.71e-2)" "unprognostic (5.02e-1)" "validated prognostic unfavorable (4.01e-6)" "validated prognostic unfavorable (6.89e-4)" "unprognostic (4.04e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.56e-1)" "unprognostic (2.03e-1)" "unprognostic (1.90e-1)" "unprognostic (4.60e-2)" ADRA1D "ADRA1, ADRA1A, ADRA1R" ENSG00000171873 "Adrenoceptor alpha 1D" P25100 20 4220630-4249287 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.8;cervix: 7.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.0;Inhibitory neurons: 2.3;Sertoli cells: 8.2;Smooth muscle cells: 6.8" "Group enriched" "Detected in many" 4 "CGE interneuron: 14.8;deep-layer near-projecting: 6.0;hippocampal CA1-3: 12.2;hippocampal CA4: 8.7;LAMP5-LHX6 and Chandelier: 15.6;mammillary body: 9.3;MGE interneuron: 5.0;splatter: 6.0;thalamic excitatory: 10.6;vascular associated smooth muscle cell: 3.9" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 27.8" "Adipose visceral - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038789 Uncertain NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 48: Smooth muscle cells - Signal transduction" 13 "HPA038789: AB_10673475" "unprognostic (6.41e-2)" "unprognostic (4.95e-2)" "unprognostic (4.86e-2)" "unprognostic (2.05e-3)" AMOTL1 JEAP ENSG00000166025 "Angiomotin like 1" Q8IY63 11 94706431-94876748 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 108.1" "Cell type enhanced" "Detected in many" "Early spermatids: 96.1;Late spermatids: 86.2;Skeletal myocytes: 66.4" "Cell type enhanced" "Detected in all" "fibroblast: 227.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001196 Approved Approved "Cell Junctions,Cytosol" NA NA 21000 "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 11: Late spermatids - Unknown function" 27 Cytosol "Cell Junctions" "HPA001196: AB_1078147" "unprognostic (3.12e-1)" "unprognostic (3.05e-1)" "unprognostic (9.10e-3)" "unprognostic (3.00e-3)" "unprognostic (1.76e-2)" "unprognostic (9.98e-2)" "unprognostic (6.51e-2)" "potential prognostic favorable (5.39e-4)" "unprognostic (1.72e-2)" "unprognostic (3.61e-2)" "validated prognostic favorable (1.34e-7)" "validated prognostic favorable (2.52e-4)" "unprognostic (6.70e-2)" "unprognostic (1.13e-1)" "unprognostic (6.54e-3)" "unprognostic (1.27e-1)" "unprognostic (1.10e-1)" "unprognostic (2.89e-1)" "unprognostic (1.69e-1)" "unprognostic (1.26e-1)" "unprognostic (1.47e-2)" "unprognostic (1.77e-1)" "unprognostic (2.07e-1)" "unprognostic (7.57e-2)" "unprognostic (1.46e-2)" "unprognostic (9.05e-2)" "unprognostic (4.91e-2)" "unprognostic (9.90e-3)" "unprognostic (1.30e-1)" "unprognostic (3.69e-2)" "unprognostic (7.73e-2)" AMZ1 KIAA1950 ENSG00000174945 "Archaelysin family metallopeptidase 1" Q400G9 7 2679522-2775500 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 5.0" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 98.1;Oocytes: 84.6" "Group enriched" "Detected in all" 4 "committed oligodendrocyte precursor: 104.8;oligodendrocyte precursor cell: 300.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.8;thyroid cancer: 4.7" "Pituitary gland - Gonadotropes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020233 Uncertain NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 17 "HPA020233: AB_1844818" "unprognostic (7.04e-2)" "unprognostic (7.27e-2)" "unprognostic (2.38e-2)" "unprognostic (9.22e-3)" "unprognostic (1.02e-1)" "unprognostic (8.13e-3)" "unprognostic (9.53e-2)" "unprognostic (8.71e-2)" ANGPTL7 "AngX, CDT6" ENSG00000171819 "Angiopoietin like 7" O43827 1 11189355-11195981 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.4" "Cell type enriched" "Detected in some" 4 "Schwann cells: 74.5" "Cell type enhanced" "Detected in many" "fibroblast: 4.7" "Cancer enriched" "Detected in some" 16 "Skin Cuteneous Melanoma (TCGA): 32.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells" "Not detected" "Not detected" "Region enriched" "Detected in all" 13 "spinal cord: 82.5" "Secreted in other tissues" "No annotated function" NA NA 590000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 14 "unprognostic (1.50e-1)" "unprognostic (1.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.31e-1)" "unprognostic (5.38e-2)" "unprognostic (3.43e-2)" "unprognostic (8.36e-2)" ANKRD34C ENSG00000235711 "Ankyrin repeat domain 34C" P0C6C1 15 79282722-79298239 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.9;Horizontal cells: 1.3;Inhibitory neurons: 1.8" "Cell type enhanced" "Detected in many" "mammillary body: 9.2;midbrain-derived inhibitory: 9.0;thalamic excitatory: 7.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Pancreas - Beta cells, Skeletal muscle - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045329 Approved Mitochondria NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 8: Neurons - Neuronal signaling" Mitochondria "HPA045329: AB_2679291" AP1B1 "ADTB1, AP105A, BAM22, CLAPB2" ENSG00000100280 "Adaptor related protein complex 1 subunit beta 1" Q10567 22 29327680-29388583 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 127.1" "Cell type enriched" "Detected in all" 5 "central nervous system macrophage: 308.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Macrophages, Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065226, HPA068520" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 590000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 58: Macrophages - Innate immune response" 37 "Golgi apparatus" "Vesicles, Cytosol" "HPA065226: AB_2685438, HPA068520: AB_2685998" "unprognostic (1.40e-2)" "unprognostic (3.18e-2)" "unprognostic (1.47e-1)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (2.90e-2)" "unprognostic (2.93e-1)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" "unprognostic (4.97e-2)" "potential prognostic favorable (4.23e-6)" "unprognostic (3.45e-2)" "unprognostic (4.81e-3)" "potential prognostic unfavorable (7.57e-5)" "unprognostic (1.54e-2)" "unprognostic (1.98e-1)" "unprognostic (3.82e-3)" "unprognostic (6.99e-2)" "unprognostic (8.44e-3)" "unprognostic (3.61e-2)" "unprognostic (3.32e-1)" "unprognostic (1.05e-2)" "unprognostic (2.74e-2)" "unprognostic (1.18e-1)" "unprognostic (2.21e-1)" "unprognostic (6.14e-2)" "unprognostic (2.26e-1)" "unprognostic (9.69e-2)" "unprognostic (1.33e-1)" "unprognostic (2.70e-2)" "unprognostic (1.34e-1)" APC "DP2, DP2.5, DP3, PPP1R46" ENSG00000134982 "APC regulator of WNT signaling pathway" P25054 5 112707498-112846239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.0" "Cell type enhanced" "Detected in many" "Astrocytes: 508.7;Bipolar cells: 165.3;Inhibitory neurons: 226.6;Oligodendrocyte precursor cells: 184.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013349, HPA013362" Supported Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 17: Neuronal - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Astrocytes - Unknown function" 92 "Plasma membrane" "Golgi apparatus" "HPA013349: AB_1844913, HPA013362: " "unprognostic (9.53e-2)" "unprognostic (7.72e-2)" "unprognostic (2.61e-1)" "unprognostic (4.76e-2)" "unprognostic (1.47e-1)" "unprognostic (1.77e-1)" "unprognostic (1.33e-1)" "unprognostic (1.87e-1)" "unprognostic (1.13e-2)" "unprognostic (1.55e-2)" "potential prognostic favorable (2.40e-6)" "unprognostic (3.11e-3)" "unprognostic (1.78e-1)" "unprognostic (2.57e-1)" "unprognostic (4.04e-2)" "unprognostic (3.48e-2)" "unprognostic (2.78e-1)" "unprognostic (1.33e-1)" "unprognostic (1.23e-1)" "unprognostic (8.62e-3)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (2.17e-1)" "unprognostic (1.87e-1)" "unprognostic (1.12e-1)" "unprognostic (7.56e-2)" "unprognostic (3.37e-3)" "unprognostic (4.45e-1)" "unprognostic (1.04e-1)" "unprognostic (3.20e-1)" "unprognostic (7.53e-3)" "unprognostic (2.04e-1)" AREL1 "FIEL1, KIAA0317" ENSG00000119682 "Apoptosis resistant E3 ubiquitin protein ligase 1" O15033 14 74653437-74713117 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051306 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 74: Neutrophils - Degranulation" 9 "HPA051306: AB_2681433" "unprognostic (1.20e-2)" "unprognostic (6.11e-2)" "unprognostic (2.42e-2)" "unprognostic (1.58e-1)" "unprognostic (2.54e-1)" "unprognostic (1.12e-1)" "unprognostic (6.58e-3)" "unprognostic (6.85e-2)" "unprognostic (1.99e-1)" "potential prognostic favorable (2.68e-6)" "unprognostic (6.27e-2)" "unprognostic (1.89e-2)" "unprognostic (4.23e-2)" "unprognostic (1.87e-1)" "unprognostic (4.42e-1)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (6.74e-3)" "unprognostic (1.02e-1)" "unprognostic (1.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.48e-1)" "unprognostic (5.57e-3)" "unprognostic (5.15e-3)" "unprognostic (2.00e-1)" "unprognostic (5.98e-2)" "unprognostic (4.19e-1)" "unprognostic (2.84e-2)" "unprognostic (4.72e-2)" ARHGAP27 "CAMGAP1, FLJ43547, SH3D20, SH3P20" ENSG00000159314 "Rho GTPase activating protein 27" Q6ZUM4 17 45393902-45434421 "Predicted intracellular proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 95.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 80.9;Paneth cells: 68.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary gland basal cells, Spleen - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023919, HPA053053" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 2 "Nucleoplasm, Cytosol" "HPA023919: AB_2059402, HPA053053: AB_2682027" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.92e-3)" "unprognostic (2.01e-1)" "potential prognostic favorable (3.33e-4)" "unprognostic (1.25e-1)" "unprognostic (2.16e-2)" "unprognostic (9.22e-3)" "unprognostic (2.07e-1)" "unprognostic (3.61e-1)" "unprognostic (5.98e-2)" "unprognostic (3.01e-1)" "unprognostic (6.81e-2)" "unprognostic (1.71e-2)" "unprognostic (9.30e-2)" "unprognostic (3.47e-2)" "unprognostic (2.36e-2)" "unprognostic (2.91e-2)" "unprognostic (2.45e-1)" "unprognostic (1.70e-1)" "unprognostic (3.21e-1)" "unprognostic (1.29e-2)" "unprognostic (9.71e-2)" "unprognostic (4.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-2)" "unprognostic (1.67e-2)" "unprognostic (1.07e-1)" "unprognostic (1.15e-1)" "unprognostic (9.22e-2)" "unprognostic (6.15e-2)" ARHGAP35 "GRF-1, GRLF1, KIAA1722, P190A, p190ARhoGAP, p190RhoGAP" ENSG00000160007 "Rho GTPase activating protein 35" Q9NRY4 19 46860997-47005077 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, GTPase activation, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 679.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037311, HPA055184, HPA056470" Approved Approved "Nuclear bodies,Microtubules,Aggresome" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 44: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 12 "Nuclear bodies" "Microtubules, Aggresome" "CAB037311: AB_477435, HPA055184: AB_2682730, HPA056470: AB_2683142" "unprognostic (3.73e-2)" "unprognostic (1.63e-2)" "unprognostic (1.29e-3)" "unprognostic (1.69e-2)" "unprognostic (4.89e-2)" "unprognostic (5.11e-3)" "unprognostic (1.54e-1)" "unprognostic (3.90e-2)" "unprognostic (4.69e-1)" "validated prognostic favorable (8.75e-9)" "validated prognostic favorable (9.71e-4)" "unprognostic (3.04e-2)" "unprognostic (5.91e-3)" "unprognostic (1.97e-1)" "unprognostic (8.54e-2)" "unprognostic (2.53e-1)" "unprognostic (1.13e-1)" "unprognostic (2.93e-2)" "unprognostic (2.98e-2)" "unprognostic (3.29e-2)" "unprognostic (5.18e-2)" "unprognostic (3.09e-1)" "unprognostic (2.88e-1)" "unprognostic (1.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (2.72e-1)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-1)" ARRB1 ARR1 ENSG00000137486 "Arrestin beta 1" P49407 11 75260122-75351705 "Predicted intracellular proteins, Transporters" "Protein transport, Transcription, Transcription regulation, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 137.5" "Group enriched" "Detected in many" 5 "dendritic cells: 42.5;granulocytes: 49.7;monocytes: 137.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003763, HPA049318, HPA070249" Approved Supported Nucleoplasm NA NA 3100000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 119 Nucleoplasm "CAB003763: AB_562248, HPA049318: AB_2680711, HPA070249: AB_2732151" "unprognostic (1.45e-1)" "unprognostic (8.91e-2)" "unprognostic (4.22e-1)" "unprognostic (2.98e-2)" "unprognostic (2.11e-1)" "unprognostic (1.24e-2)" "unprognostic (6.48e-2)" "unprognostic (1.20e-3)" "unprognostic (2.26e-3)" "unprognostic (9.58e-2)" "potential prognostic favorable (1.50e-7)" "unprognostic (1.12e-3)" "unprognostic (1.91e-1)" "unprognostic (3.43e-3)" "unprognostic (4.53e-2)" "potential prognostic favorable (3.34e-5)" "unprognostic (2.50e-1)" "unprognostic (2.10e-2)" "unprognostic (3.39e-1)" "unprognostic (1.89e-1)" "unprognostic (2.17e-1)" "unprognostic (3.83e-1)" "unprognostic (1.68e-1)" "unprognostic (2.53e-1)" "unprognostic (9.93e-2)" "unprognostic (3.10e-2)" "unprognostic (3.07e-1)" "unprognostic (4.07e-1)" "unprognostic (7.29e-2)" "unprognostic (1.46e-1)" "unprognostic (1.25e-1)" ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 334.1;Late spermatids: 474.7;Oligodendrocyte precursor cells: 583.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.7" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.7;monocytes: 6.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565, CAB080440" Enhanced Approved "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA 26000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 76: Oligodendrocyte precursor - Unknown function" 30 "Golgi apparatus, Plasma membrane" "Centriolar satellite" "CAB037292: AB_476723, CAB080440: , HPA011136: AB_2668438, HPA048565: AB_2680445" "unprognostic (9.08e-2)" "unprognostic (1.38e-2)" "unprognostic (2.48e-2)" "unprognostic (5.72e-3)" "unprognostic (5.39e-2)" "unprognostic (1.14e-1)" "unprognostic (1.96e-1)" "unprognostic (1.23e-1)" "unprognostic (5.55e-2)" "unprognostic (3.90e-3)" "potential prognostic favorable (4.71e-5)" "unprognostic (9.62e-2)" "potential prognostic unfavorable (3.50e-4)" "potential prognostic unfavorable (2.41e-6)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (1.31e-5)" "unprognostic (5.62e-3)" "unprognostic (4.38e-2)" "unprognostic (1.89e-1)" "unprognostic (4.29e-3)" "unprognostic (3.10e-1)" "unprognostic (1.72e-2)" "potential prognostic unfavorable (9.20e-4)" "unprognostic (4.99e-1)" "unprognostic (2.03e-1)" "unprognostic (4.59e-2)" "unprognostic (2.49e-1)" "unprognostic (1.50e-2)" "unprognostic (2.06e-1)" "unprognostic (3.51e-2)" "unprognostic (5.08e-2)" ASB18 ENSG00000182177 "Ankyrin repeat and SOCS box containing 18" Q6ZVZ8 2 236193459-236264409 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "heart muscle: 6.8;skeletal muscle: 11.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.6;Excitatory neurons: 2.8;Oocytes: 2.2;Skeletal myocytes: 2.9" "Cell type enhanced" "Detected in many" "bergmann glia: 81.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA068447 Approved Nucleoli,Mitochondria NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 68: Cardiomyocytes - Muscle contraction" Mitochondria Nucleoli "HPA068447: AB_2685991" ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family AAA domain containing 2" Q6PL18 8 123319850-123416350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 26.2;lymphoid tissue: 27.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 82.2;Spermatocytes: 108.1;Spermatogonia: 71.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Testis - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 52: Non-specific - Cell proliferation" 16 Nucleoplasm "CAB056158: AB_2665580, HPA029424: AB_10611680" "unprognostic (2.11e-1)" "unprognostic (1.51e-1)" "unprognostic (2.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" "unprognostic (1.20e-2)" "unprognostic (4.27e-1)" "unprognostic (1.37e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (3.16e-2)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (1.04e-9)" "unprognostic (2.72e-2)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (9.64e-3)" "unprognostic (6.30e-2)" "unprognostic (2.27e-1)" "unprognostic (2.03e-1)" "unprognostic (1.92e-2)" "unprognostic (2.99e-3)" "potential prognostic unfavorable (4.41e-4)" "unprognostic (1.53e-2)" "unprognostic (4.51e-2)" "unprognostic (1.45e-1)" "unprognostic (2.78e-2)" "unprognostic (6.43e-2)" "unprognostic (1.63e-1)" "unprognostic (8.91e-2)" "unprognostic (1.71e-2)" ATP2A3 SERCA3 ENSG00000074370 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3" Q93084 17 3923870-3964464 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 99.1;salivary gland: 180.1" "Cell type enhanced" "Detected in many" "B-cells: 77.7;dendritic cells: 71.0;Distal enterocytes: 113.0;Enteroendocrine cells: 73.8;Gastric mucus-secreting cells: 117.9;Intestinal goblet cells: 136.4;Plasma cells: 80.0;Serous glandular cells: 71.5" "Cell type enhanced" "Detected in many" "leukocyte: 91.1;pericyte: 29.5;vascular associated smooth muscle cell: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 134.5;lymphoma: 100.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - T-cells, Liver - T-cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells" "Region enriched" "Detected in all" 15 "cerebellum: 67.2" "Low region specificity" "Detected in all" "HPA007180, CAB010882" Approved NA NA 6700000 "Cluster 22: Eosinophils - Transcription" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 75: Serous glandular cells - Salivary secretion" 14 "CAB010882: AB_258368, HPA007180: AB_1845177" "unprognostic (7.27e-2)" "unprognostic (6.03e-2)" "unprognostic (6.76e-2)" "potential prognostic favorable (2.27e-4)" "unprognostic (3.05e-3)" "unprognostic (1.73e-1)" "unprognostic (1.13e-1)" "unprognostic (2.57e-2)" "potential prognostic favorable (4.19e-4)" "unprognostic (9.09e-3)" "potential prognostic favorable (8.67e-6)" "unprognostic (2.86e-3)" "unprognostic (1.89e-1)" "unprognostic (1.93e-2)" "unprognostic (6.61e-3)" "unprognostic (4.07e-2)" "unprognostic (9.54e-2)" "unprognostic (9.11e-3)" "unprognostic (2.58e-1)" "unprognostic (8.97e-3)" "unprognostic (1.16e-2)" "unprognostic (3.38e-3)" "unprognostic (1.82e-1)" "unprognostic (9.39e-2)" "unprognostic (2.61e-2)" "unprognostic (2.62e-3)" "unprognostic (6.42e-2)" "unprognostic (2.29e-1)" "unprognostic (4.65e-2)" "unprognostic (2.20e-1)" "unprognostic (4.04e-1)" BCL7B SMARCJ2 ENSG00000106635 "BAF chromatin remodeling complex subunit BCL7B" Q9BQE9 7 73536356-73557690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Differentiation, Wnt signaling pathway" "Allergen, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049943, HPA058069" Approved Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 80: Non-specific - Transcription" 41 Nucleoplasm "HPA049943: AB_2680963, HPA058069: AB_2683594" "unprognostic (2.00e-2)" "unprognostic (2.33e-2)" "unprognostic (1.02e-1)" "unprognostic (2.66e-2)" "unprognostic (5.70e-2)" "unprognostic (1.27e-1)" "unprognostic (2.46e-3)" "potential prognostic unfavorable (1.41e-5)" "unprognostic (3.71e-2)" "unprognostic (4.51e-2)" "potential prognostic favorable (1.02e-6)" "unprognostic (7.96e-2)" "unprognostic (1.50e-1)" "unprognostic (7.03e-3)" "unprognostic (1.50e-2)" "unprognostic (5.28e-2)" "unprognostic (2.03e-1)" "unprognostic (1.14e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (3.02e-2)" "unprognostic (2.81e-1)" "unprognostic (2.77e-1)" "unprognostic (1.96e-1)" "unprognostic (9.25e-2)" "unprognostic (7.62e-2)" "unprognostic (2.30e-1)" "unprognostic (9.34e-2)" "unprognostic (1.78e-1)" "unprognostic (2.63e-1)" "unprognostic (7.93e-3)" C1orf127 FLJ37118 ENSG00000175262 "Chromosome 1 open reading frame 127" 1 10946471-10982076 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 4.3;skeletal muscle: 16.1" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 14.9;Pancreatic endocrine cells: 13.6" "Group enriched" "Detected in some" 9 "cerebellar inhibitory: 14.9;midbrain-derived inhibitory: 15.6" "Cancer enriched" "Detected in single" 8 "Pancreatic Adenocarcinoma (TCGA): 5.4" "Region enhanced" "Detected in some" "cerebellum: 2.4" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.3" "Lineage enhanced" "Detected in single" "dendritic cells: 1.3" "Cancer enriched" "Detected in some" 5 "Myeloma: 6.0" "Heart muscle - Cardiomyocytes, Pancreas - Beta cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" HPA027654 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Nuclear speckles, Cytosol" "HPA027654: AB_10611814" "unprognostic (3.61e-1)" "unprognostic (2.90e-2)" C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 17.2;Leydig cells: 21.6;Lymphatic endothelial cells: 8.1;Peritubular cells: 30.3;Smooth muscle cells: 24.5" "Cell type enhanced" "Detected in many" "pericyte: 19.3;vascular associated smooth muscle cell: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.2" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.2" "Cancer enhanced" "Detected in some" "Sarcoma: 7.0" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Fibroblast_1, Spleen - Fibroblast_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" "Complement pathway" NA NA 1080000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 53: Fibroblasts - ECM organization" 28 "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (4.66e-3)" "unprognostic (4.38e-2)" "unprognostic (3.85e-1)" "unprognostic (3.44e-2)" "unprognostic (2.54e-1)" "unprognostic (9.14e-3)" "unprognostic (1.19e-2)" "unprognostic (7.99e-2)" "unprognostic (3.49e-2)" "unprognostic (1.42e-1)" "unprognostic (8.53e-2)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (9.85e-5)" "unprognostic (1.17e-1)" C20orf202 ENSG00000215595 "Chromosome 20 open reading frame 202" A1L168 20 1203454-1209076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 2.6" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.9;Early spermatids: 2.1;Horizontal cells: 1.3;Late spermatids: 3.5;Paneth cells: 1.2;Proximal enterocytes: 1.5;Sertoli cells: 2.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Thyroid gland - Fibroblasts" "Group enriched" "Detected in some" 15 "cerebellum: 8.0;olfactory bulb: 2.6" "Low region specificity" "Detected in many" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 11: Late spermatids - Unknown function" 7 "unprognostic (2.30e-1)" "unprognostic (2.96e-2)" "unprognostic (1.20e-3)" "unprognostic (1.13e-3)" CACNA1G "Cav3.1, NBR13" ENSG00000006283 "Calcium voltage-gated channel subunit alpha1 G" O43497 17 50560715-50627474 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 20.5;cervix: 9.5;retina: 8.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 152.8;Horizontal cells: 68.0" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 132.5;thalamic excitatory: 98.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.8;Testicular Germ Cell Tumor (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 6.8" "Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004714 Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol,Acrosome,Equatorial segment,Perinuclear theca" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Nucleoplasm, Acrosome, Equatorial segment, Perinuclear theca" "Nuclear bodies, Cytosol" "HPA004714: AB_1078368" "unprognostic (2.08e-1)" "unprognostic (2.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.05e-1)" "unprognostic (5.70e-2)" "unprognostic (4.51e-2)" CACNG5 ENSG00000075429 "Calcium voltage-gated channel auxiliary subunit gamma 5" Q9UF02 17 66835117-66894751 "FDA approved drug targets, Predicted membrane proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "retina: 15.3" "Group enriched" "Detected in some" 4 "Horizontal cells: 91.3;Oligodendrocyte precursor cells: 70.3" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 58.5;oligodendrocyte precursor cell: 52.4;thalamic excitatory: 32.0" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.0;breast cancer: 1.5;prostate cancer: 1.0" "Region enhanced" "Detected in all" "olfactory bulb: 124.3" "Low region specificity" "Detected in many" HPA050115 Uncertain NA NA "Cluster 76: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA050115: AB_2681022" "unprognostic (6.07e-3)" "unprognostic (3.71e-2)" CALML3 CLP ENSG00000178363 "Calmodulin like 3" P27482 10 5524961-5526771 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 492.8;skin 1: 173.5;vagina: 194.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 459.9;Basal squamous epithelial cells: 278.6;Squamous epithelial cells: 1470.1;Suprabasal keratinocytes: 1161.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 24 "Bladder Urothelial Carcinoma (TCGA): 222.3;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 551.9;Head and Neck Squamous Cell Carcinoma (TCGA): 593.7;Lung Squamous Cell Carcinoma (TCGA): 362.2;Skin Cuteneous Melanoma (TCGA): 171.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 96.9;Esophageal cancer: 92.1;head and neck cancer: 56.5" "Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "CAB010070, HPA044999" Approved NA NA 1600000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 56 "CAB010070: , HPA044999: AB_2679177" "unprognostic (1.90e-1)" "unprognostic (1.52e-3)" "unprognostic (4.54e-2)" "unprognostic (8.00e-2)" "unprognostic (4.20e-2)" "unprognostic (6.11e-2)" "unprognostic (4.06e-2)" "unprognostic (1.25e-1)" "unprognostic (5.61e-2)" "unprognostic (5.11e-2)" "unprognostic (8.00e-3)" "unprognostic (1.82e-1)" "unprognostic (3.08e-1)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (1.69e-1)" "unprognostic (2.62e-1)" "unprognostic (3.68e-2)" CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113418054-113761927 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 127.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 342.0;Inhibitory neurons: 192.1;Microglial cells: 178.9;Oligodendrocyte precursor cells: 190.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Primary cilium tip,Primary cilium transition zone,Perinuclear theca,Calyx,Connecting piece,Principal piece,End piece" NA NA 280000 "Cluster 18: Non-specific - Translation" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 68: Cardiomyocytes - Muscle contraction" 35 "Plasma membrane, Primary cilium tip, Primary cilium transition zone, Principal piece" "Cell Junctions, Perinuclear theca, Calyx, Connecting piece, End piece" "HPA026281: AB_1845944, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (2.30e-1)" "unprognostic (6.09e-2)" "unprognostic (3.46e-1)" "unprognostic (4.41e-2)" "unprognostic (2.29e-2)" "unprognostic (2.89e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-2)" "unprognostic (3.63e-1)" "unprognostic (2.54e-2)" "validated prognostic favorable (1.20e-4)" "validated prognostic favorable (6.77e-5)" "unprognostic (2.02e-1)" "unprognostic (2.11e-2)" "unprognostic (7.48e-2)" "unprognostic (1.74e-1)" "unprognostic (7.68e-2)" "unprognostic (6.86e-2)" "unprognostic (2.58e-2)" "unprognostic (1.92e-1)" "unprognostic (8.45e-3)" "unprognostic (3.83e-2)" "unprognostic (5.05e-1)" "unprognostic (2.63e-2)" "unprognostic (1.68e-1)" "unprognostic (3.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.83e-1)" "unprognostic (3.61e-1)" "unprognostic (2.57e-1)" CAMSAP1 "DKFZp434F195, FLJ31228" ENSG00000130559 "Calmodulin regulated spectrin associated protein 1" Q5T5Y3 9 135808487-135907546 "Predicted intracellular proteins" "Disease variant, Intellectual disability, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 102.3" "Group enriched" "Detected in all" 4 "Cone photoreceptor cells: 171.6;Rod photoreceptor cells: 229.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020527, HPA024161" Approved Supported "Mitotic spindle,Cytosol" Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 39: Retina & Testis - Cilium" "Cluster 38: Sub-cortical - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 66: Photoreceptor cells - Visual perception" 7 "Mitotic spindle, Cytosol" "HPA020527: , HPA024161: AB_1845967" "unprognostic (2.01e-1)" "unprognostic (1.92e-3)" "unprognostic (2.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (3.95e-1)" "potential prognostic favorable (3.22e-4)" "unprognostic (4.17e-2)" "unprognostic (2.85e-2)" "potential prognostic favorable (5.10e-7)" "unprognostic (2.83e-3)" "unprognostic (1.06e-1)" "unprognostic (3.30e-3)" "unprognostic (1.82e-1)" "unprognostic (3.03e-1)" "unprognostic (5.65e-3)" "unprognostic (2.28e-1)" "unprognostic (8.46e-3)" "unprognostic (9.44e-2)" "unprognostic (4.82e-2)" "unprognostic (6.23e-2)" "unprognostic (5.18e-3)" "unprognostic (8.13e-2)" "unprognostic (3.17e-2)" "unprognostic (3.04e-3)" "unprognostic (3.12e-1)" "unprognostic (1.39e-1)" "unprognostic (5.75e-1)" "unprognostic (1.30e-2)" "unprognostic (2.11e-1)" CARD11 "BIMP3, CARMA1" ENSG00000198286 "Caspase recruitment domain family member 11" Q9BXL7 7 2906142-3044228 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Immunity "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.8;lymphoid tissue: 39.5" "Group enriched" "Detected in many" 4 "B-cells: 33.5;dendritic cells: 35.8;Gastric mucus-secreting cells: 13.6;Microglial cells: 47.4;NK-cells: 51.9;Plasma cells: 13.3;T-cells: 29.9" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 272.0;leukocyte: 498.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 20.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 62.6;pancreatic cancer: 43.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052984 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 19: NK-cells - Adaptive immune response" 20 "HPA052984: AB_2682005" "unprognostic (2.29e-2)" "unprognostic (5.99e-2)" "unprognostic (4.50e-3)" "unprognostic (1.60e-1)" "unprognostic (1.13e-2)" "unprognostic (7.96e-2)" "unprognostic (2.02e-1)" "unprognostic (2.90e-1)" "unprognostic (4.36e-2)" "unprognostic (9.17e-3)" "potential prognostic unfavorable (8.76e-4)" "unprognostic (3.91e-2)" "unprognostic (8.00e-2)" "unprognostic (1.64e-1)" "unprognostic (1.61e-2)" "unprognostic (2.33e-2)" "unprognostic (4.05e-2)" "unprognostic (7.11e-2)" "unprognostic (6.71e-2)" "unprognostic (2.52e-2)" "unprognostic (1.42e-1)" "unprognostic (4.01e-2)" "unprognostic (1.45e-2)" "unprognostic (1.83e-1)" "unprognostic (5.94e-2)" "unprognostic (1.12e-2)" "unprognostic (7.97e-2)" "unprognostic (3.23e-2)" "unprognostic (7.05e-2)" "unprognostic (9.71e-2)" "unprognostic (1.75e-2)" CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1019.4" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 966.3" "Group enriched" "Detected in some" 21 "thalamic excitatory: 59.6;vascular associated smooth muscle cell: 223.7" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 2.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Breast - Endothelial cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Pituitary gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in many" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" Other NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 68: Cardiomyocytes - Muscle contraction" 10 "HPA027285: AB_1845933, HPA055298: AB_2682777" "unprognostic (3.47e-3)" "unprognostic (9.38e-2)" "unprognostic (1.07e-1)" "unprognostic (5.88e-3)" "unprognostic (6.36e-2)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (4.68e-4)" "validated prognostic favorable (3.87e-6)" "validated prognostic favorable (3.14e-7)" "unprognostic (2.23e-2)" "unprognostic (1.39e-1)" "unprognostic (1.59e-1)" "unprognostic (1.80e-1)" "unprognostic (1.23e-2)" "unprognostic (6.89e-2)" "unprognostic (5.16e-2)" "unprognostic (8.35e-2)" "unprognostic (8.09e-3)" "unprognostic (2.39e-1)" "unprognostic (3.48e-1)" CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 26.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 54.5;Granulosa cells: 53.5;Mesothelial cells: 24.9;Oocytes: 63.2;Ovarian stromal cells: 57.9;Rod photoreceptor cells: 43.4" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 458.6" "Cancer enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 12.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 8.9" "Lineage enriched" "Detected in single" 19 "granulocytes: 8.9" "Group enriched" "Detected in many" 4 "Adrenocortical cancer: 56.8;thyroid cancer: 19.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Fibroblast_2" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in all" "HPA041361, HPA041374" Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 6: Ovarian stromal cells - Transcription" 3 "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (4.22e-1)" "unprognostic (5.26e-2)" "unprognostic (1.87e-2)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (2.27e-4)" "unprognostic (4.90e-2)" "potential prognostic unfavorable (2.17e-4)" "unprognostic (6.44e-3)" "unprognostic (5.58e-2)" "unprognostic (1.88e-1)" "unprognostic (1.90e-1)" "unprognostic (1.30e-2)" "unprognostic (2.75e-1)" "unprognostic (2.28e-2)" "unprognostic (2.62e-1)" "unprognostic (1.05e-2)" "unprognostic (3.94e-3)" "unprognostic (1.12e-1)" "unprognostic (1.27e-1)" CCDC136 "DKFZP434G156, KIAA1793, NAG6" ENSG00000128596 "Coiled-coil domain containing 136" Q96JN2 7 128790757-128822132 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 85.4;retina: 50.9;testis: 180.5" "Group enriched" "Detected in many" 4 "Early spermatids: 736.4;Late spermatids: 1957.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 25.2" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010646, HPA071015" Enhanced Approved Approved "Golgi apparatus,Vesicles,Plasma membrane,Mid piece" NA NA "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 63: Late spermatids - Spermatogenesis" 8 "Plasma membrane" "Golgi apparatus, Vesicles, Mid piece" "HPA010646: , HPA071015: AB_2686334" "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" "unprognostic (9.71e-2)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (1.62e-2)" "unprognostic (2.98e-1)" "unprognostic (1.26e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-1)" "unprognostic (5.46e-3)" "unprognostic (6.28e-2)" "unprognostic (7.94e-3)" "unprognostic (2.62e-1)" "unprognostic (2.84e-1)" "unprognostic (1.35e-1)" "unprognostic (6.90e-3)" "unprognostic (3.47e-3)" "unprognostic (4.36e-3)" "unprognostic (7.51e-3)" CCDC192 LINC01183 ENSG00000230561 "Coiled-coil domain containing 192" P0DO97 5 127703361-127941507 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 13.3" "Group enriched" "Detected in some" 10 "Early spermatids: 260.8;Late spermatids: 123.7" "Cell type enhanced" "Detected in all" "fibroblast: 76.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.6" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 11: Late spermatids - Unknown function" CCNF "FBX1, FBXO1" ENSG00000162063 "Cyclin F" P41002 16 2429394-2458854 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Cyclin "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 29.2;Extravillous trophoblasts: 12.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Prostate - Prostate basal glandular cells, Skin - Sebaceous gland cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA070495, HPA071600" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" 633 Nucleoplasm Centrosome "HPA070495: AB_2686273, HPA071600: AB_2686424" "unprognostic (1.90e-2)" "unprognostic (2.09e-3)" "unprognostic (5.51e-2)" "unprognostic (8.90e-3)" "unprognostic (9.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (8.59e-2)" "unprognostic (1.11e-1)" "validated prognostic unfavorable (2.95e-9)" "validated prognostic unfavorable (1.71e-4)" "potential prognostic unfavorable (3.45e-4)" "validated prognostic unfavorable (9.57e-7)" "validated prognostic unfavorable (4.82e-5)" "unprognostic (5.43e-3)" "potential prognostic unfavorable (4.23e-4)" "unprognostic (1.14e-1)" "unprognostic (6.84e-3)" "unprognostic (1.44e-1)" "unprognostic (6.43e-2)" "unprognostic (1.38e-3)" "unprognostic (4.57e-3)" "unprognostic (3.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.83e-1)" "unprognostic (9.64e-2)" "unprognostic (9.84e-2)" "unprognostic (3.35e-2)" "unprognostic (2.48e-2)" "unprognostic (5.50e-3)" CD226 "DNAM-1, DNAM1, PTA1, TLiSA1" ENSG00000150637 "CD226 molecule" Q15762 18 69831158-69961803 "CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "lymphoid tissue: 19.7;parathyroid gland: 60.5" "Cell type enhanced" "Detected in many" "Microglial cells: 21.5;NK-cells: 101.6;Oligodendrocytes: 24.7;Schwann cells: 29.5;T-cells: 54.6" "Cell type enhanced" "Detected in all" "leukocyte: 317.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 36.7;MAIT T-cell: 13.4;memory CD4 T-cell: 28.9;memory CD8 T-cell: 22.5;naive CD4 T-cell: 15.8;naive CD8 T-cell: 17.4;NK-cell: 29.7;T-reg: 11.3" "Group enriched" "Detected in many" 11 "NK-cells: 29.7;T-cells: 36.7" "Group enriched" "Detected in some" 6 "Leukemia: 8.2;lymphoma: 10.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015715, HPA015865" Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA No 9500000 "Cluster 15: NK-cells - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA015715: AB_1846278, HPA015865: " "unprognostic (1.93e-3)" "unprognostic (2.18e-1)" "unprognostic (5.26e-2)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.15e-1)" "potential prognostic favorable (1.08e-4)" "unprognostic (1.85e-1)" "unprognostic (2.08e-3)" "unprognostic (2.37e-1)" "unprognostic (1.83e-2)" "unprognostic (1.06e-1)" "unprognostic (3.96e-2)" "unprognostic (8.63e-2)" "unprognostic (2.82e-1)" "unprognostic (4.43e-2)" CDADC1 NYD-SP15 ENSG00000102543 "Cytidine and dCMP deaminase domain containing 1" Q9BWV3 13 49247925-49293485 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 124.4;Late spermatids: 116.5;monocytes: 107.3;Spermatocytes: 40.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 9.9" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047615, HPA058314" Uncertain Approved Nucleoplasm No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" Nucleoplasm "HPA047615: AB_2680104, HPA058314: AB_2683677" "unprognostic (2.72e-1)" "unprognostic (1.07e-1)" "unprognostic (4.07e-2)" "unprognostic (5.42e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-1)" "unprognostic (1.50e-1)" "unprognostic (2.28e-1)" "potential prognostic favorable (1.27e-9)" "unprognostic (1.46e-3)" "potential prognostic favorable (2.04e-4)" "unprognostic (9.82e-3)" "unprognostic (2.57e-1)" "potential prognostic favorable (5.02e-4)" "unprognostic (9.64e-2)" "unprognostic (1.18e-1)" "unprognostic (3.12e-2)" "unprognostic (1.61e-2)" "unprognostic (5.94e-3)" "unprognostic (1.87e-2)" "unprognostic (9.06e-3)" "unprognostic (1.30e-1)" "unprognostic (6.64e-2)" "unprognostic (1.54e-1)" "unprognostic (8.81e-3)" "unprognostic (1.11e-2)" "unprognostic (1.83e-1)" "unprognostic (3.49e-3)" "unprognostic (3.65e-2)" CDH6 ENSG00000113361 "Cadherin 6" P55285 5 31193686-31329146 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 14.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 45.8;Excitatory neurons: 64.6;Microglial cells: 37.6;Oligodendrocyte precursor cells: 57.1;Proximal tubular cells: 183.4;Smooth muscle cells: 55.3" "Cell type enhanced" "Detected in many" "pericyte: 1000.4;vascular associated smooth muscle cell: 631.5" "Group enriched" "Detected in many" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 63.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 79.9;Ovary Serous Cystadenocarcinoma (TCGA): 33.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 53.6;ovarian cancer: 81.5;Uterine cancer: 44.9" "Adrenal gland - Schwann cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007047, HPA007403, HPA007456, CAB025274" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 17000000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Plasma membrane, Cell Junctions" "CAB025274: , HPA007047: AB_1078374, HPA007403: , HPA007456: AB_1078373" "unprognostic (1.07e-1)" "unprognostic (3.08e-2)" "unprognostic (4.47e-1)" "unprognostic (1.56e-2)" "unprognostic (9.49e-2)" "unprognostic (4.81e-2)" "unprognostic (2.68e-2)" "unprognostic (2.09e-3)" "unprognostic (2.12e-2)" "unprognostic (2.57e-1)" "potential prognostic favorable (2.60e-5)" "unprognostic (6.26e-3)" "unprognostic (1.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.99e-1)" "unprognostic (6.91e-2)" "unprognostic (9.86e-2)" "unprognostic (1.52e-2)" "unprognostic (3.62e-2)" "unprognostic (3.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (6.71e-2)" "unprognostic (1.44e-1)" "unprognostic (3.97e-1)" "potential prognostic unfavorable (8.87e-5)" "unprognostic (7.69e-2)" "unprognostic (2.04e-1)" "unprognostic (7.48e-2)" CEP68 KIAA0582 ENSG00000011523 "Centrosomal protein 68" Q76N32 2 65056354-65087004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040493, HPA040620" Enhanced Approved "Nucleoplasm,Cell Junctions,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 79: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 8 "Nucleoplasm, Centriolar satellite" "Cell Junctions, Basal body, Cytosol" "HPA040493: AB_10673411, HPA040620: AB_10794144" "unprognostic (1.35e-1)" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (4.22e-1)" "unprognostic (3.60e-1)" "unprognostic (1.62e-2)" "unprognostic (3.17e-2)" "potential prognostic favorable (4.29e-4)" "unprognostic (8.88e-3)" "unprognostic (1.86e-2)" "validated prognostic favorable (1.05e-8)" "validated prognostic favorable (2.28e-4)" "unprognostic (2.80e-1)" "unprognostic (5.06e-3)" "unprognostic (1.81e-1)" "unprognostic (2.10e-2)" "unprognostic (2.44e-1)" "unprognostic (6.63e-2)" "unprognostic (2.66e-2)" "unprognostic (3.65e-2)" "unprognostic (4.11e-2)" "unprognostic (3.21e-1)" "unprognostic (3.83e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-2)" "unprognostic (6.45e-2)" "unprognostic (6.09e-2)" "unprognostic (1.85e-1)" "unprognostic (4.40e-1)" "unprognostic (3.47e-2)" "unprognostic (8.37e-2)" CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "prostate: 28.1" "Group enriched" "Detected in some" 10 "Horizontal cells: 28.3;Inhibitory neurons: 14.1;Prostatic glandular cells: 21.4" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 18.9;CGE interneuron: 27.8;thalamic excitatory: 26.3" "Cancer enriched" "Detected in single" 200 "Prostate Adenocarcinoma (TCGA): 51.0" "Region enhanced" "Detected in all" "thalamus: 157.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 36 "prostate cancer: 26.6" "Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Spleen - Platelets" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "thalamus: 4.9" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (2.40e-1)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" CHRNA3 ENSG00000080644 "Cholinergic receptor nicotinic alpha 3 subunit" P32297 15 78593052-78621295 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 38.1;lymphoid tissue: 64.2;retina: 51.9" "Cell type enriched" "Detected in some" 6 "Cone photoreceptor cells: 407.8" "Group enriched" "Detected in some" 8 "cerebellar inhibitory: 55.5;midbrain-derived inhibitory: 49.0" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 20 "Neuroblastoma: 170.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029430 Enhanced Approved "Nuclear speckles,Plasma membrane,Primary cilium tip,Primary cilium transition zone,Basal body,Cytosol" NA NA "Cluster 16: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" 1 "Nuclear speckles, Plasma membrane" "Primary cilium tip, Primary cilium transition zone, Basal body, Cytosol" "HPA029430: AB_10603785" "unprognostic (2.28e-1)" "unprognostic (4.23e-2)" "unprognostic (2.44e-1)" "unprognostic (3.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.20e-1)" "unprognostic (1.65e-2)" "unprognostic (2.25e-1)" "unprognostic (2.63e-3)" "unprognostic (3.56e-1)" CHRNA4 "BFNC, EBN, EBN1" ENSG00000101204 "Cholinergic receptor nicotinic alpha 4 subunit" P43681 20 63343223-63378401 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.3;liver: 56.6;parathyroid gland: 12.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 24.4;Hepatocytes: 29.4;Horizontal cells: 49.7" "Cell type enhanced" "Detected in many" "CGE interneuron: 31.8;thalamic excitatory: 33.8" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.0" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Pituitary gland - Gonadotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 36.5;pons: 34.3;thalamus: 57.0" CAB034064 Uncertain NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 5 "CAB034064: AB_2080535" "unprognostic (1.73e-1)" "unprognostic (2.82e-1)" "potential prognostic favorable (8.99e-5)" CHRNA5 ENSG00000169684 "Cholinergic receptor nicotinic alpha 5 subunit" P30532 15 78565520-78595269 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Oocytes: 104.4;Spermatogonia: 27.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054381 Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 45: Intestine - Digestion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 44: Oocytes - Unknown function" 26 "Focal adhesion sites" "Plasma membrane" "HPA054381: AB_2682468" "unprognostic (4.42e-2)" "unprognostic (1.93e-1)" "unprognostic (1.91e-1)" "unprognostic (1.13e-1)" "unprognostic (4.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.78e-1)" "unprognostic (3.36e-1)" "unprognostic (2.08e-3)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (1.49e-6)" "potential prognostic unfavorable (9.12e-5)" "unprognostic (7.28e-3)" "unprognostic (1.24e-1)" "unprognostic (4.34e-2)" "unprognostic (6.47e-2)" "unprognostic (2.67e-2)" "unprognostic (4.42e-2)" "unprognostic (2.05e-1)" "unprognostic (1.58e-2)" "unprognostic (8.42e-2)" "unprognostic (9.05e-2)" "unprognostic (1.18e-2)" "unprognostic (2.35e-1)" "unprognostic (3.17e-1)" "unprognostic (9.68e-3)" CHRNB2 ENSG00000160716 "Cholinergic receptor nicotinic beta 2 subunit" P17787 1 154567778-154580013 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 14.3;pituitary gland: 3.5;retina: 8.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.0;Cone photoreceptor cells: 17.0;Excitatory neurons: 5.6;Horizontal cells: 21.4;Inhibitory neurons: 7.4;Late spermatids: 11.2;Rod photoreceptor cells: 5.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 18.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 2 "unprognostic (1.98e-1)" "unprognostic (3.23e-1)" "unprognostic (5.52e-3)" "unprognostic (8.35e-3)" "unprognostic (1.77e-1)" CHST1 "C6ST, KSGal6ST" ENSG00000175264 "Carbohydrate sulfotransferase 1" O43916 11 45647689-45665622 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.5" "Cell type enhanced" "Detected in many" "Astrocytes: 36.5;Early spermatids: 92.5;Excitatory neurons: 23.1;Serous glandular cells: 31.2;Spermatocytes: 75.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Fibroblast_1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060313, HPA072592" Approved Nucleoli,Mitochondria "Intracellular and membrane" Enzyme NA NA 32000 "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 2 Mitochondria Nucleoli "HPA060313: , HPA072592: " "unprognostic (1.96e-1)" "unprognostic (2.05e-3)" "unprognostic (2.27e-1)" "unprognostic (8.65e-2)" "unprognostic (2.50e-3)" "unprognostic (9.90e-2)" "unprognostic (4.39e-2)" "unprognostic (2.20e-1)" "unprognostic (3.20e-1)" "unprognostic (8.70e-2)" "unprognostic (5.50e-2)" "unprognostic (4.43e-1)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (1.43e-1)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (6.39e-5)" "unprognostic (6.55e-2)" "unprognostic (1.35e-1)" "unprognostic (9.77e-2)" "unprognostic (2.85e-1)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.94e-2)" "unprognostic (2.12e-1)" "unprognostic (2.37e-1)" "unprognostic (7.86e-3)" "unprognostic (2.71e-1)" "unprognostic (1.46e-1)" "unprognostic (1.41e-1)" CLEC16A "Gop-1, KIAA0350" ENSG00000038532 "C-type lectin domain containing 16A" Q2KHT3 16 10944539-11182186 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 124.2;Early spermatids: 120.4;Excitatory neurons: 90.2;Inhibitory neurons: 129.9;Late spermatids: 106.6;Oligodendrocytes: 67.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035814, HPA035815, HPA061385" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 8: Neurons - Neuronal signaling" 9 "Nucleoplasm, Vesicles" "HPA035814: AB_10600801, HPA035815: AB_10671937, HPA061385: AB_2684498" "unprognostic (7.31e-2)" "unprognostic (6.43e-2)" "unprognostic (2.35e-1)" "unprognostic (1.65e-1)" "unprognostic (2.95e-1)" "unprognostic (1.03e-1)" "unprognostic (2.55e-1)" "unprognostic (1.02e-3)" "unprognostic (3.36e-2)" "unprognostic (3.52e-1)" "unprognostic (1.78e-1)" "unprognostic (8.63e-2)" "unprognostic (5.04e-2)" "unprognostic (2.48e-1)" "unprognostic (5.04e-1)" "unprognostic (2.39e-2)" "unprognostic (7.07e-2)" "unprognostic (1.69e-1)" "unprognostic (2.53e-1)" "unprognostic (1.04e-2)" "unprognostic (5.37e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (7.74e-5)" "unprognostic (2.67e-2)" "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-1)" "unprognostic (2.42e-1)" "unprognostic (9.11e-2)" "unprognostic (9.37e-2)" "unprognostic (1.57e-1)" CNTN4 BIG-2 ENSG00000144619 "Contactin 4" Q8IWV2 3 2098813-3057959 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 21.8;retina: 19.2" "Cell type enhanced" "Detected in many" "Early spermatids: 484.0;Excitatory neurons: 928.6;Inhibitory neurons: 1004.1;Late spermatids: 183.8;Oligodendrocyte precursor cells: 233.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.2;Rhabdoid: 5.2" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "Cell adhesion" NA NA 110000000 "Cluster 74: Spermatids - Flagellum assembly" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "unprognostic (3.23e-1)" "unprognostic (2.05e-1)" "unprognostic (3.75e-2)" "unprognostic (3.29e-1)" "unprognostic (1.82e-1)" "potential prognostic favorable (1.38e-4)" "unprognostic (1.28e-3)" "unprognostic (8.67e-2)" "unprognostic (3.00e-2)" "unprognostic (7.84e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-2)" "unprognostic (3.95e-1)" "unprognostic (6.47e-3)" "unprognostic (1.88e-1)" "unprognostic (1.34e-1)" "unprognostic (2.09e-2)" "unprognostic (2.33e-2)" "unprognostic (1.87e-2)" "unprognostic (3.64e-2)" "unprognostic (6.46e-2)" COL4A4 CA44 ENSG00000081052 "Collagen type IV alpha 4 chain" P53420 2 227002714-227164453 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 103.2;Collecting duct cells: 40.8;Cone photoreceptor cells: 42.5;Granulosa cells: 64.4;Muller glia cells: 72.7;Oligodendrocyte precursor cells: 51.9;Skeletal myocytes: 53.7" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 194.3;pericyte: 416.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 11.8" "Region enhanced" "Detected in all" "choroid plexus: 31.8" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.7" "Lineage enriched" "Detected in single" 5 "B-cells: 2.7" "Cancer enhanced" "Detected in many" "Myeloma: 9.1" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 23: Non-specific - Cellular respiration" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Muller glia cells - Visual perception" 1 "unprognostic (1.95e-2)" "unprognostic (9.39e-2)" "unprognostic (4.12e-2)" "unprognostic (2.82e-1)" "unprognostic (4.80e-2)" "validated prognostic favorable (4.01e-10)" "validated prognostic favorable (5.20e-4)" "unprognostic (2.40e-2)" "potential prognostic favorable (2.61e-4)" "unprognostic (1.67e-2)" "unprognostic (2.54e-1)" "unprognostic (3.19e-2)" "unprognostic (7.90e-2)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (7.94e-2)" "unprognostic (1.95e-2)" "unprognostic (2.49e-2)" "unprognostic (2.67e-1)" CPNE4 "COPN4, CPN4" ENSG00000196353 "Copine 4" Q96A23 3 131533555-132285410 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 7.8;prostate: 25.3" "Cell type enriched" "Detected in some" 5 "Excitatory neurons: 338.9" "Cell type enhanced" "Detected in all" "deep-layer intratelencephalic: 1337.7;hippocampal CA4: 1403.7" "Cancer enriched" "Detected in some" 6 "Prostate Adenocarcinoma (TCGA): 37.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 8.9" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA032036, HPA078300" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA032036: AB_10600898, HPA078300: AB_2732377" "unprognostic (1.47e-1)" "unprognostic (6.03e-3)" "unprognostic (8.77e-2)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (2.26e-1)" "unprognostic (1.86e-1)" "unprognostic (3.84e-2)" "unprognostic (2.05e-2)" "unprognostic (6.44e-2)" CPNE7 ENSG00000178773 "Copine 7" Q9UBL6 16 89575758-89597246 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3;epididymis: 18.9;pituitary gland: 13.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.1;Collecting duct cells: 15.6;Excitatory neurons: 9.0;Horizontal cells: 13.2;Inhibitory neurons: 8.7;Spermatogonia: 10.5;T-cells: 9.4" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 121.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 4.9" "Lineage enriched" "Detected in single" 5 "T-cells: 4.9" "Low cancer specificity" "Detected in many" "Pituitary gland - Corticotropes, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA043359 Uncertain NA NA "Cluster 1: T-cells - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA043359: AB_10794884" "unprognostic (1.58e-3)" "unprognostic (1.11e-1)" "unprognostic (3.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.58e-2)" "unprognostic (3.52e-1)" "unprognostic (1.00e-2)" "unprognostic (1.82e-2)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (4.02e-9)" "unprognostic (6.58e-3)" "unprognostic (7.32e-2)" "unprognostic (3.30e-1)" "unprognostic (9.73e-3)" "unprognostic (8.33e-2)" "unprognostic (2.00e-1)" "unprognostic (8.11e-2)" "unprognostic (1.01e-1)" "unprognostic (4.95e-2)" "unprognostic (3.73e-2)" "unprognostic (1.59e-1)" "unprognostic (3.27e-3)" "unprognostic (5.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.17e-2)" "unprognostic (1.88e-2)" "unprognostic (4.56e-2)" "unprognostic (3.86e-1)" "unprognostic (1.13e-1)" CRYBB2 "CCA2, CRYB2, CRYB2A" ENSG00000244752 "Crystallin beta B2" P43320 22 25212564-25231870 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1" "Cell type enhanced" "Detected in some" "Astrocytes: 1.9;Excitatory neurons: 2.3;Late spermatids: 8.0;Lymphatic endothelial cells: 3.2;Microglial cells: 1.8" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 11.0;hippocampal CA1-3: 11.7" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.2" "Region enhanced" "Detected in some" "hippocampal formation: 1.7" "Low region specificity" "Detected in many" HPA043749 Supported Approved Nucleoplasm NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 63: Late spermatids - Spermatogenesis" 12 Nucleoplasm "HPA043749: AB_2678652" "unprognostic (7.33e-2)" "unprognostic (4.00e-1)" "unprognostic (6.58e-2)" CRYBB3 CRYB3 ENSG00000100053 "Crystallin beta B3" P26998 22 25199858-25207359 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 4 "Muller glia cells: 3.8;Oocytes: 5.1;Proximal tubular cells: 9.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA055840 Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 37 Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA055840: AB_2682939" "unprognostic (5.16e-3)" "unprognostic (4.14e-2)" "unprognostic (1.42e-1)" "unprognostic (2.83e-1)" "unprognostic (4.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.80e-2)" "unprognostic (1.35e-3)" "unprognostic (1.17e-2)" "unprognostic (1.76e-1)" CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 172.7;skin 1: 421.1" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 541.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Cytosol NA NA 20000 "Cluster 45: Eosinophils - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 23 "Nucleoplasm, Cytosol" "HPA067089: " "unprognostic (5.60e-3)" "unprognostic (1.61e-1)" "unprognostic (4.11e-1)" "unprognostic (1.37e-1)" "unprognostic (2.00e-3)" "unprognostic (1.31e-1)" "unprognostic (3.71e-1)" "unprognostic (2.13e-2)" "unprognostic (3.60e-2)" "unprognostic (1.15e-1)" "potential prognostic favorable (8.90e-8)" "unprognostic (1.73e-2)" "unprognostic (1.17e-2)" "validated prognostic unfavorable (3.04e-4)" "validated prognostic unfavorable (4.50e-5)" "unprognostic (2.39e-2)" "unprognostic (2.04e-2)" "unprognostic (1.92e-2)" "unprognostic (3.87e-2)" "unprognostic (8.81e-2)" "unprognostic (2.11e-1)" "unprognostic (1.47e-2)" "unprognostic (3.93e-2)" "unprognostic (1.46e-1)" "unprognostic (3.68e-1)" "unprognostic (1.17e-1)" "unprognostic (4.42e-2)" "unprognostic (1.56e-2)" "unprognostic (3.69e-2)" "unprognostic (5.71e-2)" "unprognostic (1.07e-2)" CYFIP2 PIR121 ENSG00000055163 "Cytoplasmic FMR1 interacting protein 2" Q96F07 5 157266079-157395595 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 85.0;kidney: 135.1" "Cell type enhanced" "Detected in many" "Astrocytes: 126.6;Collecting duct cells: 124.5;Excitatory neurons: 113.8;Inhibitory neurons: 141.2;Oligodendrocyte precursor cells: 113.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 78.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 173.5" "Adipose subcutaneous - Smooth muscle cells, Breast - T-cells, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB055519, HPA068106, HPA071459" Uncertain Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 460000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 32: Smooth muscle cells - Muscle contraction" 31 "Endoplasmic reticulum" "Plasma membrane, Cytosol" "CAB055519: , HPA068106: AB_2685955, HPA071459: AB_2686400" "unprognostic (2.85e-3)" "unprognostic (3.43e-2)" "unprognostic (1.28e-1)" "unprognostic (1.86e-1)" "unprognostic (1.08e-2)" "unprognostic (1.59e-2)" "unprognostic (2.07e-1)" "unprognostic (2.90e-2)" "unprognostic (1.72e-1)" "unprognostic (7.58e-2)" "potential prognostic favorable (2.81e-13)" "unprognostic (7.72e-3)" "unprognostic (1.85e-2)" "unprognostic (1.30e-1)" "unprognostic (7.76e-3)" "unprognostic (1.75e-3)" "unprognostic (3.44e-2)" "unprognostic (3.84e-2)" "unprognostic (2.68e-2)" "unprognostic (2.65e-1)" "unprognostic (1.07e-1)" "potential prognostic favorable (3.02e-4)" "unprognostic (4.11e-1)" "unprognostic (2.10e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-2)" "unprognostic (3.04e-2)" "unprognostic (1.54e-1)" "unprognostic (9.57e-2)" "unprognostic (8.00e-2)" "unprognostic (4.60e-2)" CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 93.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011713, HPA050095, HPA077163" Approved Supported "Nucleoplasm,Primary cilium transition zone,Centriolar satellite,Basal body,Principal piece" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 140 "Centriolar satellite" "Nucleoplasm, Primary cilium transition zone, Basal body, Principal piece" "CAB011713: AB_731794, HPA050095: AB_2681013, HPA077163: " "unprognostic (4.08e-2)" "unprognostic (2.28e-1)" "unprognostic (5.67e-3)" "unprognostic (1.24e-1)" "unprognostic (6.54e-2)" "unprognostic (6.35e-2)" "unprognostic (1.77e-1)" "unprognostic (2.53e-1)" "unprognostic (1.18e-1)" "unprognostic (5.58e-2)" "potential prognostic favorable (4.60e-4)" "unprognostic (6.53e-2)" "unprognostic (2.06e-1)" "unprognostic (7.95e-2)" "unprognostic (4.17e-3)" "unprognostic (1.87e-2)" "unprognostic (1.33e-1)" "unprognostic (6.64e-2)" "unprognostic (3.59e-1)" "unprognostic (7.34e-2)" "unprognostic (5.01e-3)" "unprognostic (1.55e-1)" "unprognostic (1.39e-2)" "unprognostic (2.06e-1)" "unprognostic (1.84e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (8.86e-2)" "unprognostic (1.74e-1)" "unprognostic (7.56e-3)" "unprognostic (3.10e-1)" CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338601 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "placenta: 120.5" "Cell type enriched" "Detected in some" 61 "Syncytiotrophoblasts: 2667.7" "Cell type enhanced" "Detected in some" "medium spiny neuron: 4.6;thalamic excitatory: 10.8" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "lymphoma: 5.3;testis cancer: 15.0" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000355, HPA051194" Enhanced Uncertain Mitochondria NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 38: Sub-cortical - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 17 Mitochondria "CAB000355: , HPA051194: AB_2681381" "unprognostic (2.17e-2)" "unprognostic (1.79e-2)" "unprognostic (2.29e-1)" "unprognostic (9.85e-2)" "unprognostic (1.23e-1)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (2.91e-6)" "unprognostic (2.22e-2)" "unprognostic (3.30e-1)" "unprognostic (5.17e-2)" "unprognostic (2.42e-1)" CYP27C1 FLJ16008 ENSG00000186684 "Cytochrome P450 family 27 subfamily C member 1" Q4G0S4 2 127183832-127220313 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.0;skin 1: 4.9" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.9;Endometrial stromal cells: 7.0;Ionocytes: 3.3;Leydig cells: 7.8;Suprabasal keratinocytes: 3.8" "Cell type enriched" "Detected in many" 6 "thalamic excitatory: 43.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Schwann cells, Spleen - B-cells (Spleen)" "HPA062460, HPA068731" Enhanced Vesicles NA NA "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 9: Endometrial stromal cells - Transcription" Vesicles "HPA062460: AB_2732683, HPA068731: AB_2686023" "unprognostic (1.36e-1)" "unprognostic (3.52e-1)" "unprognostic (2.71e-1)" "unprognostic (4.74e-2)" "unprognostic (1.15e-3)" "unprognostic (5.03e-2)" "unprognostic (6.38e-3)" "unprognostic (1.61e-2)" "unprognostic (7.34e-3)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" "validated prognostic unfavorable (8.31e-4)" "validated prognostic unfavorable (4.03e-6)" "unprognostic (1.67e-2)" "unprognostic (1.23e-2)" "unprognostic (1.49e-1)" CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 86.5;intestine: 81.0;liver: 141.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 109.3;Cytotrophoblasts: 115.0;Oligodendrocytes: 63.7;Proximal enterocytes: 116.3;Syncytiotrophoblasts: 252.2" "Cell type enhanced" "Detected in many" "astrocyte: 77.1;bergmann glia: 181.5;oligodendrocyte: 127.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 112.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.3" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" Enzyme NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 83: Liver - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Cytotrophoblasts - Mitochondria" 3 "unprognostic (2.24e-1)" "unprognostic (9.84e-2)" "unprognostic (8.35e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (3.20e-2)" "unprognostic (6.61e-2)" "unprognostic (3.35e-1)" "unprognostic (1.60e-1)" "validated prognostic favorable (2.04e-6)" "validated prognostic favorable (8.16e-7)" "potential prognostic unfavorable (6.44e-4)" "unprognostic (1.99e-1)" "potential prognostic favorable (9.77e-4)" "unprognostic (4.30e-2)" "unprognostic (1.70e-1)" "unprognostic (6.05e-2)" "unprognostic (9.72e-2)" "unprognostic (8.78e-2)" "unprognostic (2.41e-2)" "unprognostic (5.47e-2)" "unprognostic (1.37e-3)" "unprognostic (1.94e-1)" "unprognostic (5.26e-2)" "unprognostic (1.60e-3)" "unprognostic (2.55e-1)" "unprognostic (3.41e-1)" "unprognostic (7.17e-3)" DBNDD1 "FLJ12582, MGC3101" ENSG00000003249 "Dysbindin domain containing 1" Q9H9R9 16 90004871-90019890 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 89.2;skeletal muscle: 46.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.1;Cholangiocytes: 21.0;Exocrine glandular cells: 17.8" "Cell type enhanced" "Detected in many" "thalamic excitatory: 26.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "naive B-cell: 12.9" "Lineage enriched" "Detected in many" 4 "B-cells: 12.9" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043018 Uncertain Approved "Nuclear speckles,Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" No No "Cluster 34: B-cells - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 1 "Nuclear speckles" "Cytosol, Equatorial segment, Mid piece, Principal piece, End piece" "HPA043018: AB_10794921" "unprognostic (7.83e-2)" "unprognostic (6.26e-2)" "unprognostic (4.39e-2)" "unprognostic (1.70e-2)" "unprognostic (2.35e-1)" "unprognostic (1.47e-2)" "unprognostic (7.20e-2)" "unprognostic (9.89e-3)" "unprognostic (1.40e-1)" "unprognostic (9.63e-3)" "unprognostic (1.91e-3)" "unprognostic (2.63e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (1.56e-1)" "unprognostic (5.16e-2)" "unprognostic (1.55e-1)" "unprognostic (6.52e-2)" "unprognostic (1.54e-1)" "unprognostic (4.37e-1)" "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" "unprognostic (1.15e-1)" "unprognostic (3.30e-1)" "unprognostic (3.25e-2)" "unprognostic (3.06e-2)" "unprognostic (1.46e-1)" "unprognostic (5.65e-2)" "unprognostic (8.23e-2)" "unprognostic (3.60e-1)" "unprognostic (1.66e-1)" "unprognostic (1.37e-1)" DCSTAMP "DC-STAMP, FIND, TM7SF4" ENSG00000164935 "Dendrocyte expressed seven transmembrane protein" Q9H295 8 104339087-104356689 "Predicted membrane proteins, Transporters" "Differentiation, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.9;lung: 3.7" "Group enriched" "Detected in some" 4 "Hofbauer cells: 6.4;Macrophages: 9.8" "Group enriched" "Detected in some" 6 "amygdala excitatory: 13.4;deep-layer intratelencephalic: 4.9;hippocampal CA4: 8.1;thalamic excitatory: 5.2" "Cancer enriched" "Detected in some" 58 "Thyroid Carcinoma (TCGA): 64.9" "Region enhanced" "Detected in many" "amygdala: 9.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 1.6;thyroid cancer: 3.1" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 53: Non-specific - Glycosylation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 58: Macrophages - Innate immune response" 1 "unprognostic (3.55e-3)" "unprognostic (2.72e-2)" "unprognostic (3.22e-1)" "unprognostic (1.15e-2)" "unprognostic (1.00e-1)" "unprognostic (1.42e-1)" DEFB1 "BD1, DEFB-1, DEFB101, HBD-1, HBD1, MGC51822" ENSG00000164825 "Defensin beta 1" P60022 8 6870592-6877936 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 1698.6;pancreas: 725.9;salivary gland: 1917.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 1848.7;Distal tubular cells: 12736.3;Ductal cells: 1962.9;Mucus glandular cells: 5835.8;Salivary duct cells: 3325.3" "Group enriched" "Detected in some" 6 "fibroblast: 2.5;midbrain-derived inhibitory: 4.9;thalamic excitatory: 5.9" "Group enriched" "Detected in many" 6 "Kidney Chromophobe (TCGA): 2427.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 690.1" "Group enriched" "Detected in many" 5 "amygdala: 2.9;cerebellum: 3.4;hypothalamus: 1.8;midbrain: 4.7;thalamus: 6.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 57.7;ovarian cancer: 43.5" "Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Secreted in other tissues" Defense NA NA 1100000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (2.66e-1)" "unprognostic (2.97e-1)" "unprognostic (4.11e-2)" "unprognostic (2.64e-1)" "unprognostic (2.28e-2)" "unprognostic (2.28e-1)" "unprognostic (5.92e-2)" "unprognostic (7.70e-2)" "unprognostic (1.19e-1)" "unprognostic (4.25e-2)" "unprognostic (1.21e-2)" "unprognostic (3.31e-1)" "unprognostic (1.06e-3)" "potential prognostic unfavorable (4.03e-4)" "unprognostic (1.05e-1)" "unprognostic (5.52e-2)" "unprognostic (2.03e-2)" "unprognostic (2.77e-2)" "unprognostic (4.58e-1)" "unprognostic (4.05e-3)" "unprognostic (2.14e-1)" "unprognostic (3.57e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (7.27e-4)" "unprognostic (1.69e-1)" "unprognostic (1.92e-1)" "unprognostic (1.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.27e-1)" DGCR6L FLJ10666 ENSG00000128185 "DiGeorge syndrome critical region gene 6 like" Q9BY27 22 20314238-20320080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 8 "Late spermatids: 2639.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 63: Late spermatids - Spermatogenesis" 14 "unprognostic (2.39e-2)" "unprognostic (1.52e-1)" "unprognostic (4.07e-1)" "potential prognostic favorable (3.41e-4)" "unprognostic (1.26e-1)" "unprognostic (2.69e-2)" "unprognostic (4.01e-2)" "unprognostic (6.14e-2)" "unprognostic (1.48e-1)" "unprognostic (6.75e-2)" "unprognostic (1.74e-2)" "unprognostic (3.05e-2)" "unprognostic (1.68e-3)" "unprognostic (1.48e-1)" "unprognostic (5.94e-2)" "unprognostic (8.19e-3)" "unprognostic (2.10e-1)" "unprognostic (6.51e-2)" "unprognostic (1.81e-1)" "unprognostic (3.86e-2)" "unprognostic (2.45e-1)" "unprognostic (1.29e-2)" "unprognostic (1.82e-1)" "unprognostic (2.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.58e-1)" "unprognostic (4.29e-2)" "unprognostic (1.01e-1)" "unprognostic (1.37e-1)" "unprognostic (4.35e-1)" "unprognostic (2.46e-1)" DKK2 ENSG00000155011 "Dickkopf WNT signaling pathway inhibitor 2" Q9UBU2 4 106921802-107283806 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 14.6" "Cell type enhanced" "Detected in some" "Endothelial cells: 5.7;Fibroblasts: 19.1;Hofbauer cells: 14.8;Inhibitory neurons: 30.9;Langerhans cells: 5.8" "Cell type enhanced" "Detected in many" "endothelial cell: 100.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 35.1;Neuroblastoma: 19.4;Rhabdoid: 47.7" "Minor Salivary Gland - Fibroblasts" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cerebral cortex: 2.1;midbrain: 6.6;pons: 8.2;thalamus: 7.6" "CAB009727, HPA052611" Uncertain Supported "Golgi apparatus" "Secreted in other tissues" "Developmental protein" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 33 "Golgi apparatus" "CAB009727: AB_2091492, HPA052611: AB_2732576" "unprognostic (4.10e-2)" "unprognostic (1.75e-3)" "unprognostic (3.93e-1)" "unprognostic (1.67e-2)" "unprognostic (1.12e-1)" "unprognostic (9.31e-2)" "unprognostic (3.38e-2)" "unprognostic (1.78e-1)" "unprognostic (2.00e-2)" "unprognostic (2.31e-1)" "unprognostic (4.28e-3)" "unprognostic (5.00e-2)" "unprognostic (3.00e-1)" "unprognostic (9.73e-2)" "unprognostic (1.82e-1)" "unprognostic (2.55e-1)" "unprognostic (6.17e-2)" "unprognostic (7.53e-2)" "unprognostic (3.48e-2)" "unprognostic (2.05e-1)" DLGAP3 "DAP3, SAPAP3" ENSG00000116544 "DLG associated protein 3" O95886 1 34865436-34929650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 44.5" "Cell type enhanced" "Detected in many" "Early spermatids: 22.6;Excitatory neurons: 37.8;Hofbauer cells: 11.0;Inhibitory neurons: 26.7;Late spermatids: 18.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.3" "Adipose visceral - Macrophages, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026445, HPA027304" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody" Yes NA "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 8 "Endoplasmic reticulum" "Plasma membrane, Midbody" "HPA026445: AB_1847733, HPA027304: " "unprognostic (2.99e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (5.51e-4)" "unprognostic (2.46e-1)" "unprognostic (7.82e-3)" "unprognostic (2.34e-1)" "unprognostic (1.42e-2)" DLGAP4 "DAP4, KIAA0964, SAPAP4" ENSG00000080845 "DLG associated protein 4" Q9Y2H0 20 36306336-36528637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 211.2;Oocytes: 196.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054105, HPA056378" Approved Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 63: Late spermatids - Spermatogenesis" 9 Nucleoplasm "Vesicles, Focal adhesion sites" "HPA054105: AB_2682381, HPA056378: " "unprognostic (3.53e-2)" "unprognostic (7.92e-2)" "unprognostic (2.96e-1)" "unprognostic (1.24e-1)" "unprognostic (3.44e-1)" "unprognostic (1.92e-1)" "unprognostic (1.28e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-1)" "unprognostic (2.89e-3)" "unprognostic (1.72e-1)" "unprognostic (1.93e-1)" "unprognostic (4.70e-2)" "potential prognostic unfavorable (7.42e-7)" "unprognostic (2.09e-1)" "unprognostic (5.72e-2)" "unprognostic (5.69e-2)" "unprognostic (3.55e-2)" "unprognostic (2.55e-1)" "unprognostic (2.66e-2)" "unprognostic (2.72e-1)" "unprognostic (2.29e-2)" "potential prognostic unfavorable (5.68e-4)" "unprognostic (2.95e-2)" "unprognostic (1.57e-1)" "unprognostic (6.27e-2)" "unprognostic (3.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" "unprognostic (2.99e-1)" DPM2 "MGC111193, MGC21559" ENSG00000136908 "Dolichyl-phosphate mannosyltransferase subunit 2, regulatory" O94777 9 127935099-127937854 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Congenital disorder of glycosylation, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064623 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 1: Erythroid cells - Oxygen transport" 4 "HPA064623: AB_2685303" "unprognostic (2.27e-3)" "unprognostic (2.69e-2)" "unprognostic (1.22e-2)" "unprognostic (3.87e-1)" "unprognostic (7.51e-3)" "potential prognostic unfavorable (8.85e-4)" "unprognostic (1.58e-1)" "potential prognostic favorable (9.89e-4)" "unprognostic (1.31e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-2)" "unprognostic (6.96e-2)" "potential prognostic favorable (2.15e-4)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (7.14e-2)" "unprognostic (2.37e-1)" "unprognostic (9.68e-2)" "unprognostic (8.73e-2)" "unprognostic (4.13e-2)" "unprognostic (7.53e-2)" "unprognostic (8.64e-2)" "unprognostic (2.10e-2)" "unprognostic (3.93e-2)" "unprognostic (1.36e-1)" "unprognostic (4.88e-2)" "unprognostic (3.83e-2)" "unprognostic (1.25e-1)" "unprognostic (6.26e-3)" "unprognostic (1.54e-1)" "unprognostic (2.93e-1)" "unprognostic (3.92e-2)" DPP9 ENSG00000142002 "Dipeptidyl peptidase 9" Q86TI2 19 4674341-4724673 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036059 Approved Supported Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" 5 Cytosol "HPA036059: AB_10671240" "unprognostic (2.87e-2)" "unprognostic (4.72e-2)" "unprognostic (2.51e-3)" "unprognostic (1.15e-2)" "unprognostic (2.46e-1)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "unprognostic (2.08e-1)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (1.32e-1)" "unprognostic (7.74e-2)" "unprognostic (2.77e-1)" "unprognostic (8.11e-2)" "unprognostic (2.70e-2)" "unprognostic (5.12e-2)" "unprognostic (2.21e-2)" "unprognostic (8.35e-2)" "unprognostic (1.41e-1)" "unprognostic (5.88e-2)" "unprognostic (9.67e-2)" "unprognostic (2.93e-2)" "potential prognostic unfavorable (1.56e-5)" "unprognostic (3.64e-2)" "unprognostic (3.74e-2)" "unprognostic (6.79e-2)" "unprognostic (2.19e-1)" "unprognostic (1.64e-2)" "unprognostic (1.84e-1)" "unprognostic (2.31e-2)" "unprognostic (2.82e-2)" DPYS DHPase ENSG00000147647 Dihydropyrimidinase Q14117 8 104330324-104467055 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "kidney: 192.1;liver: 463.1" "Group enriched" "Detected in some" 8 "Hepatocytes: 393.7;Mesothelial cells: 158.7;Proximal tubular cells: 373.4" "Cell type enhanced" "Detected in many" "thalamic excitatory: 106.6" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 126.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.2" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA024785, HPA070814" Enhanced NA NA 420000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 10 "HPA024785: AB_1847856, HPA070814: " "potential prognostic favorable (4.90e-6)" "unprognostic (3.55e-3)" "unprognostic (4.78e-2)" "unprognostic (1.43e-3)" "potential prognostic favorable (5.00e-4)" "unprognostic (2.18e-3)" "unprognostic (9.54e-2)" "unprognostic (4.75e-1)" DTX2 "KIAA1528, RNF58" ENSG00000091073 "Deltex E3 ubiquitin ligase 2" Q86UW9 7 76461676-76505995 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 52.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 80.9;Ionocytes: 83.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 42.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042931 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 126 "Nucleoplasm, Nuclear membrane" "HPA042931: AB_2678227" "unprognostic (6.33e-2)" "unprognostic (2.81e-2)" "unprognostic (4.48e-2)" "unprognostic (1.18e-1)" "unprognostic (9.02e-2)" "unprognostic (8.14e-2)" "unprognostic (4.12e-2)" "unprognostic (1.62e-1)" "unprognostic (8.82e-2)" "unprognostic (1.37e-3)" "unprognostic (1.55e-1)" "unprognostic (2.77e-1)" "unprognostic (1.28e-2)" "potential prognostic unfavorable (4.02e-4)" "unprognostic (1.74e-3)" "unprognostic (6.69e-3)" "unprognostic (6.82e-2)" "unprognostic (1.55e-1)" "unprognostic (1.67e-1)" "unprognostic (3.60e-2)" "unprognostic (5.68e-2)" "unprognostic (3.97e-2)" "unprognostic (2.34e-2)" "unprognostic (4.29e-1)" "unprognostic (8.54e-2)" "unprognostic (9.32e-2)" "unprognostic (2.11e-1)" "unprognostic (3.62e-2)" "unprognostic (5.08e-1)" "unprognostic (1.27e-1)" "unprognostic (1.82e-1)" DYRK1B MIRK ENSG00000105204 "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 19 39825350-39834201 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 126.6;testis: 81.5" "Group enriched" "Detected in all" 11 "Early spermatids: 151.2;Late spermatids: 548.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028522, HPA028786" Uncertain Supported "Nucleoplasm,Mitotic chromosome" Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 72: Testis & Skeletal muscle - Protein ubiquitination" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 36: Late spermatids - Unknown function" 51 Nucleoplasm "Mitotic chromosome" "HPA028522: AB_2672656, HPA028786: AB_10670831" "unprognostic (4.38e-3)" "unprognostic (1.51e-1)" "unprognostic (4.14e-1)" "unprognostic (7.03e-2)" "unprognostic (1.60e-1)" "unprognostic (2.77e-1)" "unprognostic (1.17e-1)" "unprognostic (2.61e-2)" "unprognostic (5.93e-3)" "unprognostic (2.64e-1)" "unprognostic (1.27e-2)" "unprognostic (5.31e-2)" "potential prognostic favorable (8.31e-5)" "unprognostic (1.21e-1)" "unprognostic (4.05e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "unprognostic (1.46e-2)" "unprognostic (7.85e-2)" "unprognostic (1.25e-3)" "unprognostic (1.35e-1)" "unprognostic (1.33e-1)" "unprognostic (4.26e-2)" "unprognostic (3.75e-2)" "unprognostic (2.00e-1)" "unprognostic (6.45e-2)" "unprognostic (3.55e-1)" "unprognostic (1.03e-1)" "unprognostic (5.39e-2)" "unprognostic (2.03e-1)" "unprognostic (4.34e-2)" EEF2KMT "EFM3, FAM86A, MGC19636, SB153" ENSG00000118894 "Eukaryotic elongation factor 2 lysine methyltransferase" Q96G04 16 5084284-5097795 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Early spermatids: 108.7;Late spermatids: 372.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" HPA041610 Approved Uncertain Vesicles NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 11: Late spermatids - Unknown function" 14 Vesicles "HPA041610: AB_2677581" "unprognostic (1.03e-2)" "unprognostic (2.62e-2)" "unprognostic (2.37e-2)" "unprognostic (1.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (3.30e-4)" "unprognostic (5.94e-2)" "unprognostic (3.55e-1)" "unprognostic (2.59e-2)" "unprognostic (6.95e-2)" "unprognostic (1.93e-1)" "unprognostic (1.44e-3)" "unprognostic (1.29e-2)" "unprognostic (1.62e-2)" "unprognostic (4.69e-2)" "unprognostic (1.30e-1)" "unprognostic (7.33e-3)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (2.51e-4)" "unprognostic (2.66e-1)" "unprognostic (1.47e-1)" "unprognostic (3.57e-2)" "unprognostic (8.18e-2)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (3.71e-1)" "unprognostic (1.68e-1)" "unprognostic (6.85e-2)" EFNA2 "ELF-1, EPLG6, LERK6" ENSG00000099617 "Ephrin A2" O43921 19 1285873-1301431 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "gallbladder: 3.4;intestine: 12.0;liver: 12.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 21.0;Distal enterocytes: 56.7;Intestinal goblet cells: 18.0;Paneth cells: 32.4;Proximal enterocytes: 56.4;Undifferentiated cells: 19.6" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 14.9" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 16.2;Rectum Adenocarcinoma (TCGA): 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.0" "Colon - Colon enterocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067567 Approved Mitochondria,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 5: Enterocytes - Absorption" 33 "Mitochondria, Cytosol" "HPA067567: AB_2732771" "unprognostic (3.03e-2)" "unprognostic (1.13e-2)" "unprognostic (7.54e-3)" "potential prognostic favorable (9.43e-4)" "unprognostic (1.10e-1)" "unprognostic (2.56e-2)" "unprognostic (6.25e-2)" "unprognostic (7.93e-2)" "unprognostic (5.19e-3)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (1.00e-2)" "unprognostic (3.02e-2)" "unprognostic (2.90e-1)" "unprognostic (1.55e-2)" "unprognostic (2.64e-1)" "unprognostic (6.90e-2)" "unprognostic (7.22e-2)" "unprognostic (2.09e-2)" EHBP1 "KIAA0903, NACSIN" ENSG00000115504 "EH domain binding protein 1" Q8NDI1 2 62673851-63046487 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 192.9;Excitatory neurons: 253.5;Inhibitory neurons: 235.0;Late spermatids: 508.1;Oligodendrocyte precursor cells: 212.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035468, HPA035469" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 11: Late spermatids - Unknown function" 4 "Plasma membrane" Cytosol "HPA035468: AB_10671513, HPA035469: AB_10601365" "unprognostic (3.78e-2)" "unprognostic (1.10e-1)" "unprognostic (2.53e-1)" "unprognostic (6.34e-3)" "unprognostic (2.50e-1)" "unprognostic (1.83e-1)" "unprognostic (5.47e-2)" "unprognostic (2.76e-2)" "unprognostic (3.29e-2)" "unprognostic (6.84e-2)" "potential prognostic favorable (1.95e-7)" "unprognostic (5.73e-3)" "unprognostic (1.96e-1)" "unprognostic (1.61e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (2.23e-1)" "unprognostic (1.31e-1)" "unprognostic (3.67e-2)" "unprognostic (1.90e-2)" "unprognostic (1.24e-1)" "unprognostic (2.15e-3)" "unprognostic (1.93e-3)" "unprognostic (1.20e-1)" "unprognostic (1.65e-1)" "unprognostic (4.03e-2)" "unprognostic (3.04e-1)" "unprognostic (3.67e-2)" "unprognostic (1.57e-1)" "unprognostic (2.85e-2)" "unprognostic (1.04e-2)" ENSG00000258417 ENSG00000258417 "Novel protein" 8 132024238-132085655 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Testicular Germ Cell Tumor (TCGA): 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "unprognostic (1.47e-1)" EPS15L1 eps15R ENSG00000127527 "Epidermal growth factor receptor pathway substrate 15 like 1" Q9UBC2 19 16355239-16472085 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019237, HPA055309" Approved Approved Vesicles NA NA 47000 "Cluster 32: Basophils - Transcription" "Cluster 79: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 21: Early spermatids - Spermatogenesis" 47 Vesicles "HPA019237: AB_1848223, HPA055309: AB_2682780" "unprognostic (5.32e-2)" "unprognostic (7.79e-2)" "unprognostic (8.90e-2)" "unprognostic (9.82e-3)" "unprognostic (4.08e-1)" "unprognostic (9.63e-2)" "unprognostic (2.72e-1)" "unprognostic (2.32e-1)" "unprognostic (1.86e-1)" "unprognostic (1.00e-1)" "unprognostic (3.67e-1)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.98e-3)" "unprognostic (1.48e-2)" "unprognostic (2.82e-1)" "unprognostic (5.79e-2)" "unprognostic (1.07e-1)" "unprognostic (3.28e-2)" "unprognostic (5.44e-3)" "unprognostic (5.48e-2)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (3.01e-3)" "unprognostic (8.55e-2)" "unprognostic (1.24e-3)" "unprognostic (4.58e-3)" "unprognostic (1.03e-2)" "unprognostic (3.40e-1)" "unprognostic (2.29e-1)" "unprognostic (9.28e-2)" ERCC2 "EM9, MAG, MGC102762, MGC126218, MGC126219, XPD" ENSG00000104884 "ERCC excision repair 2, TFIIH core complex helicase subunit" P18074 19 45349837-45370918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase, Isomerase" "Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 64.7;Spermatocytes: 30.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005375, HPA038057, HPA069266" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 44: Oocytes - Unknown function" 37 Nucleoplasm Cytosol "CAB005375: AB_2100152, HPA038057: AB_2675810, HPA069266: AB_2686104" "unprognostic (1.11e-1)" "unprognostic (1.93e-1)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "unprognostic (1.97e-2)" "unprognostic (9.38e-2)" "unprognostic (2.39e-1)" "unprognostic (8.75e-3)" "unprognostic (1.98e-2)" "potential prognostic favorable (4.09e-5)" "unprognostic (4.11e-2)" "potential prognostic favorable (9.44e-4)" "unprognostic (2.92e-3)" "unprognostic (2.31e-3)" "unprognostic (6.35e-2)" "unprognostic (1.76e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (8.02e-3)" "unprognostic (3.23e-3)" "unprognostic (3.05e-2)" "unprognostic (2.23e-1)" "unprognostic (1.57e-3)" "unprognostic (5.66e-2)" "unprognostic (3.70e-2)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" "unprognostic (8.41e-2)" "unprognostic (3.25e-3)" "unprognostic (4.52e-2)" EXTL3 "botv, REGR" ENSG00000012232 "Exostosin like glycosyltransferase 3" O43909 8 28600469-28756561 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 42.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025387 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Smooth muscle cells - Muscle contraction" 34 "CAB025387: " "unprognostic (5.58e-2)" "unprognostic (2.94e-2)" "unprognostic (4.82e-1)" "unprognostic (5.27e-2)" "unprognostic (4.30e-3)" "unprognostic (2.21e-1)" "unprognostic (1.36e-1)" "unprognostic (1.35e-1)" "unprognostic (1.20e-1)" "unprognostic (4.80e-3)" "potential prognostic favorable (1.19e-6)" "unprognostic (1.33e-3)" "unprognostic (5.16e-3)" "potential prognostic unfavorable (4.24e-5)" "unprognostic (3.08e-2)" "unprognostic (9.19e-3)" "unprognostic (1.92e-2)" "unprognostic (7.04e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (2.46e-3)" "unprognostic (8.52e-2)" "unprognostic (2.52e-2)" "unprognostic (1.47e-2)" "unprognostic (3.79e-2)" "unprognostic (1.77e-2)" "unprognostic (3.87e-1)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (4.58e-2)" "unprognostic (3.91e-2)" F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186266189-186289681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 235.6" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 69.2" "Cell type enriched" "Detected in some" 9 "midbrain-derived inhibitory: 33.8" "Cancer enriched" "Detected in some" 12 "Liver Hepatocellular Carcinoma (TCGA): 46.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.8" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039808 Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 2800000000 "Cluster 83: Liver - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" Vesicles "HPA039808: AB_2676693" "unprognostic (1.91e-2)" "potential prognostic favorable (4.99e-4)" "unprognostic (2.90e-3)" "validated prognostic favorable (1.19e-4)" "validated prognostic favorable (5.80e-6)" "unprognostic (3.74e-2)" "unprognostic (6.64e-2)" "unprognostic (6.81e-2)" "unprognostic (4.06e-2)" FAM20A DKFZp434F2322 ENSG00000108950 "FAM20A golgi associated secretory pathway pseudokinase" Q96MK3 17 68535113-68601367 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 49.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.8;Hepatocytes: 56.0;Hofbauer cells: 81.0;Late spermatids: 197.5;Serous glandular cells: 98.5" "Group enriched" "Detected in all" 5 "fibroblast: 205.2;thalamic excitatory: 67.9;vascular associated smooth muscle cell: 61.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Adipose subcutaneous - Adipose progenitor cells, Colon - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048964 Approved "Secreted in other tissues" Other NA NA 14000000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "HPA048964: AB_2680575" "unprognostic (1.65e-1)" "unprognostic (2.21e-2)" "unprognostic (4.38e-2)" "unprognostic (7.16e-2)" "unprognostic (1.80e-1)" "unprognostic (4.45e-2)" "unprognostic (6.99e-2)" "unprognostic (8.23e-2)" "potential prognostic unfavorable (3.56e-7)" "unprognostic (7.26e-2)" "unprognostic (2.61e-1)" "unprognostic (3.63e-3)" "potential prognostic favorable (3.42e-4)" "unprognostic (9.80e-3)" "unprognostic (5.62e-3)" "unprognostic (2.52e-3)" "unprognostic (1.72e-1)" "unprognostic (1.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (8.60e-2)" "unprognostic (1.37e-1)" "unprognostic (7.87e-3)" "unprognostic (5.32e-2)" "unprognostic (1.45e-1)" "unprognostic (8.26e-2)" FAM20C "DKFZp547D065, DMP4, G-CK, IMAGE:4942737" ENSG00000177706 "FAM20C golgi associated secretory pathway kinase" Q8IXL6 7 192571-260772 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 78.7;Serous glandular cells: 113.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 50.0" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019823 Supported "Nucleoplasm,Golgi apparatus" "Secreted in other tissues" Enzyme NA NA 150000000 "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 75: Serous glandular cells - Salivary secretion" 5 "Golgi apparatus" Nucleoplasm "HPA019823: AB_1848389" "unprognostic (1.31e-1)" "unprognostic (4.50e-2)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (3.00e-2)" "unprognostic (8.39e-2)" "unprognostic (2.31e-3)" "unprognostic (2.50e-2)" "unprognostic (8.29e-2)" "potential prognostic favorable (8.81e-6)" "potential prognostic favorable (1.27e-4)" "unprognostic (1.87e-2)" "unprognostic (1.38e-1)" "unprognostic (1.83e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-2)" "unprognostic (4.03e-2)" "unprognostic (2.90e-2)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (1.90e-3)" "unprognostic (9.29e-2)" "unprognostic (3.31e-1)" "unprognostic (2.64e-1)" "unprognostic (3.62e-1)" "unprognostic (1.35e-2)" "unprognostic (3.46e-1)" "unprognostic (4.15e-3)" "unprognostic (9.69e-2)" "unprognostic (1.45e-1)" "unprognostic (2.60e-2)" FAM210B "C20orf108, dJ1167H4.1, DKFZP434A1114" ENSG00000124098 "Family with sequence similarity 210 member B" Q96KR6 20 56358974-56368663 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 291.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042652 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 56: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 1: Erythroid cells - Oxygen transport" 58 "Plasma membrane, Cytosol" "HPA042652: AB_2678098" "unprognostic (8.26e-2)" "unprognostic (1.62e-1)" "unprognostic (4.53e-2)" "unprognostic (2.54e-1)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "unprognostic (3.37e-2)" "unprognostic (5.77e-2)" "unprognostic (4.34e-2)" "potential prognostic favorable (7.61e-6)" "unprognostic (3.94e-2)" "unprognostic (3.96e-2)" "unprognostic (2.06e-1)" "potential prognostic favorable (7.15e-4)" "unprognostic (1.50e-1)" "unprognostic (1.43e-1)" "unprognostic (1.04e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-1)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (2.13e-1)" "unprognostic (2.20e-2)" "unprognostic (4.99e-3)" "unprognostic (7.73e-2)" "unprognostic (1.14e-1)" "unprognostic (6.07e-2)" "unprognostic (9.22e-2)" "unprognostic (1.03e-3)" FAM32A "DKFZP586O0120, OTAG-12" ENSG00000105058 "Family with sequence similarity 32 member A" Q9Y421 19 16185380-16192046 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051712 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 38: Sub-cortical - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 4 "Nucleoplasm, Nucleoli" "HPA051712: AB_2681582" "unprognostic (1.20e-1)" "unprognostic (5.11e-2)" "unprognostic (1.72e-1)" "unprognostic (5.23e-2)" "unprognostic (8.76e-2)" "unprognostic (7.01e-2)" "unprognostic (7.29e-2)" "unprognostic (1.87e-2)" "unprognostic (1.17e-1)" "unprognostic (8.07e-3)" "unprognostic (2.58e-3)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "validated prognostic unfavorable (2.41e-4)" "validated prognostic unfavorable (3.75e-4)" "unprognostic (1.72e-1)" "unprognostic (1.55e-2)" "unprognostic (5.13e-2)" "unprognostic (1.34e-3)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (1.53e-2)" "unprognostic (2.12e-1)" "unprognostic (2.37e-3)" "unprognostic (1.27e-1)" "unprognostic (3.39e-1)" "unprognostic (4.52e-2)" "unprognostic (3.00e-1)" "unprognostic (7.52e-2)" "unprognostic (7.93e-2)" "unprognostic (2.70e-2)" FAM53C C5orf6 ENSG00000120709 "Family with sequence similarity 53 member C" Q9NYF3 5 138331935-138349729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 83.5" "Group enriched" "Detected in all" 5 "Early spermatids: 250.0;Late spermatids: 600.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 29.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 29.5" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042796 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 63: Late spermatids - Spermatogenesis" 33 "HPA042796: AB_10794158" "unprognostic (1.17e-3)" "unprognostic (1.19e-1)" "unprognostic (1.78e-1)" "unprognostic (1.17e-2)" "unprognostic (2.27e-1)" "unprognostic (1.62e-1)" "unprognostic (2.44e-1)" "unprognostic (2.21e-3)" "unprognostic (1.82e-1)" "unprognostic (3.50e-2)" "potential prognostic favorable (1.21e-4)" "unprognostic (2.66e-2)" "unprognostic (2.98e-1)" "unprognostic (1.08e-3)" "unprognostic (4.84e-3)" "unprognostic (1.68e-1)" "unprognostic (6.73e-3)" "unprognostic (2.02e-1)" "unprognostic (1.36e-1)" "unprognostic (1.93e-2)" "unprognostic (8.67e-3)" "unprognostic (9.07e-2)" "unprognostic (5.72e-2)" "unprognostic (1.60e-1)" "unprognostic (1.34e-2)" "unprognostic (2.03e-1)" "unprognostic (1.06e-1)" "unprognostic (6.17e-2)" "unprognostic (2.05e-1)" "unprognostic (8.27e-3)" "unprognostic (6.33e-2)" FBXO10 FBX10 ENSG00000147912 "F-box protein 10" Q9UK96 9 37510892-37576380 "Disease related genes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 28.7" "Cell type enhanced" "Detected in many" "Early spermatids: 20.3;Excitatory neurons: 27.7;Inhibitory neurons: 27.0;Late spermatids: 50.6;Oligodendrocyte precursor cells: 15.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 2.1;naive B-cell: 1.3" "Lineage enriched" "Detected in single" 5 "B-cells: 2.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002863, HPA072721" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 79: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 8: Neurons - Neuronal signaling" 3 "Nucleoplasm, Cytosol" "HPA002863: AB_10965996, HPA072721: " "unprognostic (1.07e-2)" "unprognostic (4.95e-2)" "unprognostic (1.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.56e-1)" "unprognostic (1.52e-2)" "unprognostic (2.18e-1)" "unprognostic (2.66e-3)" "unprognostic (5.74e-2)" "unprognostic (8.23e-2)" "potential prognostic favorable (4.81e-4)" "unprognostic (8.44e-2)" "unprognostic (2.13e-3)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (1.37e-1)" "unprognostic (2.16e-1)" "unprognostic (1.69e-1)" "unprognostic (3.02e-1)" "unprognostic (1.03e-1)" "unprognostic (3.10e-2)" "unprognostic (3.75e-1)" "unprognostic (3.58e-3)" "unprognostic (8.62e-3)" "unprognostic (2.84e-1)" "unprognostic (2.43e-1)" "unprognostic (7.21e-2)" "unprognostic (3.73e-2)" "unprognostic (9.65e-2)" "unprognostic (8.98e-2)" "unprognostic (1.54e-1)" "unprognostic (2.17e-1)" FLRT1 "MGC21624, SPG68" ENSG00000126500 "Fibronectin leucine rich transmembrane protein 1" 11 64035931-64119173 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 7.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 8.5;Horizontal cells: 7.6;Inhibitory neurons: 15.3;Muller glia cells: 5.7;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 12.2;Schwann cells: 9.4" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 36.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.6" "Colon - Enteric glia cells, Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054589 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 "HPA054589: AB_2682533" "unprognostic (5.73e-3)" "unprognostic (6.43e-2)" "unprognostic (2.15e-1)" "potential prognostic favorable (2.02e-4)" "unprognostic (5.27e-2)" "unprognostic (8.92e-3)" "unprognostic (3.01e-3)" "unprognostic (1.82e-1)" FNDC5 FRCP2 ENSG00000160097 "Fibronectin type III domain containing 5" Q8NAU1 1 32862268-32872482 "Predicted membrane proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 311.6;tongue: 459.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 52.9;Cardiomyocytes: 83.0;Horizontal cells: 44.1;Muller glia cells: 39.7;Serous glandular cells: 38.6;Skeletal myocytes: 45.9" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 86.4;midbrain-derived inhibitory: 120.5" "Group enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 6.8;Kidney Chromophobe (TCGA): 4.9;Liver Hepatocellular Carcinoma (TCGA): 8.9;Testicular Germ Cell Tumor (TCGA): 17.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Neuroblastoma: 21.7;Sarcoma: 36.8" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051290 Enhanced "Intracellular and membrane" Hormone NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 53: Fibroblasts - ECM organization" "HPA051290: AB_2681422" "unprognostic (9.81e-2)" "unprognostic (9.41e-2)" "unprognostic (4.11e-2)" "unprognostic (1.57e-3)" "unprognostic (3.85e-2)" "unprognostic (4.41e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (1.63e-2)" "unprognostic (2.70e-2)" "unprognostic (3.39e-1)" "unprognostic (1.10e-1)" "unprognostic (5.71e-2)" "unprognostic (2.07e-1)" "unprognostic (5.99e-3)" "unprognostic (7.41e-2)" "unprognostic (6.33e-3)" FOXP2 "CAGH44, SPCH1, TNRC10" ENSG00000128573 "Forkhead box P2" O15409 7 114086327-114693772 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.2" "Group enriched" "Detected in many" 5 "Excitatory neurons: 179.9;Microglial cells: 275.5" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 2928.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000382, HPA000383, HPA001679" Enhanced Enhanced Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 31 Nucleoplasm "HPA000382: AB_1078908, HPA000383: AB_1078909, HPA001679: AB_2666415" "unprognostic (1.35e-1)" "unprognostic (2.43e-1)" "unprognostic (4.88e-2)" "unprognostic (1.07e-1)" "unprognostic (2.03e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.01e-1)" "unprognostic (8.60e-3)" "unprognostic (1.66e-1)" "unprognostic (2.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.06e-3)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" "unprognostic (2.79e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-1)" "unprognostic (9.14e-2)" "unprognostic (3.99e-2)" "unprognostic (1.80e-1)" "unprognostic (4.95e-3)" "unprognostic (3.60e-1)" "unprognostic (1.94e-1)" "unprognostic (1.17e-1)" "unprognostic (1.34e-3)" "unprognostic (1.16e-1)" "unprognostic (4.50e-3)" "unprognostic (8.07e-2)" FRAS1 "FLJ14927, FLJ22031, KIAA1500" ENSG00000138759 "Fraser extracellular matrix complex subunit 1" Q86XX4 4 78057323-78544269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 11.6" "Group enriched" "Detected in many" 10 "Excitatory neurons: 197.6;Inhibitory neurons: 362.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051601 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 8: Neurons - Neuronal signaling" 2 "HPA051601: AB_2681547" "unprognostic (6.10e-2)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (7.51e-2)" "unprognostic (2.16e-1)" "unprognostic (2.60e-1)" "unprognostic (1.54e-1)" "validated prognostic favorable (2.70e-7)" "validated prognostic favorable (1.37e-4)" "unprognostic (2.67e-1)" "unprognostic (1.73e-3)" "unprognostic (7.02e-2)" "unprognostic (8.20e-2)" "unprognostic (1.83e-1)" "unprognostic (1.69e-2)" "unprognostic (7.75e-3)" "unprognostic (4.12e-2)" "unprognostic (8.82e-2)" "unprognostic (4.98e-2)" "unprognostic (5.02e-1)" "unprognostic (4.46e-2)" "unprognostic (2.62e-2)" "unprognostic (7.11e-2)" "unprognostic (1.28e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-3)" "unprognostic (2.53e-3)" FRMPD1 "FRMD2, KIAA0967" ENSG00000070601 "FERM and PDZ domain containing 1" Q5SYB0 9 37650954-37746904 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 66.8" "Group enriched" "Detected in some" 4 "Bipolar cells: 46.9;Cone photoreceptor cells: 81.6;Inhibitory neurons: 23.3;Rod photoreceptor cells: 78.2" "Cell type enhanced" "Detected in many" "CGE interneuron: 48.1;LAMP5-LHX6 and Chandelier: 67.1;midbrain-derived inhibitory: 51.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.4" "Group enriched" "Detected in many" 5 "granulocytes: 3.4;NK-cells: 1.5" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Pituitary gland - Gonadotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042934 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 39: Retina & Testis - Cilium" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 66: Photoreceptor cells - Visual perception" 1 "HPA042934: AB_10960422" "unprognostic (6.58e-2)" "unprognostic (4.94e-2)" "unprognostic (6.95e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (2.59e-2)" "unprognostic (1.51e-1)" "unprognostic (4.01e-2)" "unprognostic (1.72e-3)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (2.11e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (3.36e-4)" "unprognostic (1.18e-1)" "unprognostic (6.01e-2)" "unprognostic (6.46e-3)" "unprognostic (1.61e-1)" "unprognostic (9.05e-2)" "unprognostic (3.75e-3)" "unprognostic (4.72e-2)" "unprognostic (1.73e-1)" "unprognostic (9.93e-2)" "unprognostic (1.73e-3)" "unprognostic (3.27e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (9.95e-2)" FSTL4 KIAA1061 ENSG00000053108 "Follistatin like 4" Q6MZW2 5 133196455-133612541 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 377.7" "Cell type enhanced" "Detected in all" "thalamic excitatory: 714.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 52.3" "Kidney - Intercalated cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045920, HPA070859" Uncertain Approved Vesicles "Secreted to blood" "No annotated function" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA045920: AB_10965844, HPA070859: " "unprognostic (2.47e-1)" "unprognostic (7.69e-3)" "unprognostic (2.90e-2)" "unprognostic (3.92e-1)" "unprognostic (1.02e-2)" "unprognostic (3.15e-1)" "unprognostic (8.36e-2)" "unprognostic (1.61e-1)" "unprognostic (2.28e-1)" "unprognostic (2.81e-2)" "unprognostic (1.41e-2)" "unprognostic (2.34e-1)" "unprognostic (3.97e-2)" "unprognostic (3.45e-2)" "unprognostic (2.62e-1)" "unprognostic (3.82e-2)" "unprognostic (3.45e-1)" "unprognostic (1.80e-2)" "unprognostic (1.58e-1)" "unprognostic (2.36e-2)" "unprognostic (3.57e-2)" "unprognostic (1.07e-1)" "unprognostic (9.83e-2)" "unprognostic (1.06e-1)" "unprognostic (4.44e-2)" "unprognostic (1.82e-1)" "unprognostic (3.17e-2)" "unprognostic (2.44e-2)" FZD9 "CD349, FZD3" ENSG00000188763 "Frizzled class receptor 9" O00144 7 73433778-73436120 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.2;skeletal muscle: 6.8;testis: 4.5" "Cell type enhanced" "Detected in some" "Early spermatids: 4.2;Late spermatids: 13.7;Muller glia cells: 5.4;Oligodendrocyte precursor cells: 14.1" "Group enriched" "Detected in many" 5 "fibroblast: 13.2;oligodendrocyte precursor cell: 19.5;pericyte: 10.2" "Cancer enriched" "Detected in many" 5 "Skin Cuteneous Melanoma (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 11: Late spermatids - Unknown function" "unprognostic (1.18e-1)" "unprognostic (2.13e-2)" "unprognostic (1.66e-1)" "unprognostic (1.38e-1)" "unprognostic (1.71e-1)" "unprognostic (2.58e-1)" "unprognostic (2.29e-1)" "unprognostic (8.22e-2)" "unprognostic (1.43e-2)" GABBR1 "GPRC3A, hGB1a" ENSG00000204681 "Gamma-aminobutyric acid type B receptor subunit 1" Q9UBS5 6 29555629-29633976 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 228.8" "Cell type enhanced" "Detected in many" "Astrocytes: 142.7;Excitatory neurons: 56.7;Horizontal cells: 56.0;Inhibitory neurons: 65.2;Oligodendrocyte precursor cells: 67.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050483 Uncertain Uncertain "Basal body,Cytosol" "Intracellular and membrane" Receptor NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Astrocytes - Unknown function" 13 "Basal body, Cytosol" "HPA050483: AB_2681140" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (3.41e-1)" "unprognostic (3.21e-1)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (1.33e-1)" "potential prognostic favorable (5.87e-5)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (7.31e-7)" "unprognostic (2.47e-2)" "unprognostic (2.53e-1)" "potential prognostic favorable (5.06e-5)" "unprognostic (1.22e-2)" "unprognostic (1.02e-1)" "unprognostic (1.54e-2)" "unprognostic (9.51e-2)" "unprognostic (4.62e-2)" "unprognostic (1.15e-2)" "unprognostic (1.97e-3)" "unprognostic (1.35e-2)" "unprognostic (2.53e-1)" "unprognostic (1.57e-1)" "unprognostic (8.89e-2)" "unprognostic (2.78e-1)" "unprognostic (1.84e-1)" "unprognostic (4.55e-2)" "unprognostic (1.47e-1)" GALNT14 "FLJ12691, GalNac-T10, GalNac-T14" ENSG00000158089 "Polypeptide N-acetylgalactosaminyltransferase 14" Q96FL9 2 30910467-31155202 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 39.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 27.9;Inhibitory neurons: 75.8;Oocytes: 17.6;Proximal enterocytes: 19.2;Proximal tubular cells: 34.6" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 361.5;midbrain-derived inhibitory: 754.6" "Group enriched" "Detected in many" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 117.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 97.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "neutrophil: 8.5" "Lineage enriched" "Detected in many" 8 "granulocytes: 8.5" "Cancer enriched" "Detected in many" 5 "Kidney cancer: 123.7" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030138 Approved "Nucleoplasm,Golgi apparatus" NA NA 12000 "Cluster 20: Non-specific - DNA binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus" Nucleoplasm "HPA030138: AB_2673332" "unprognostic (1.92e-2)" "unprognostic (7.90e-2)" "unprognostic (7.01e-2)" "unprognostic (1.62e-1)" "unprognostic (2.05e-3)" "potential prognostic favorable (1.07e-6)" "unprognostic (4.66e-3)" "unprognostic (2.00e-1)" "validated prognostic favorable (5.97e-10)" "validated prognostic favorable (2.96e-4)" "unprognostic (9.96e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (3.03e-3)" "unprognostic (6.76e-2)" "unprognostic (2.65e-1)" "unprognostic (7.67e-2)" "unprognostic (2.24e-1)" "unprognostic (1.62e-3)" "unprognostic (2.05e-3)" "unprognostic (2.07e-1)" "unprognostic (6.02e-2)" "unprognostic (1.12e-2)" "unprognostic (4.70e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-2)" GALNTL6 "GalNAc-T6L, GALNT17" ENSG00000174473 "Polypeptide N-acetylgalactosaminyltransferase like 6" Q49A17 4 171812254-173041559 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 4.0;lymphoid tissue: 2.5;testis: 2.4" "Group enriched" "Detected in some" 17 "Excitatory neurons: 410.5;Inhibitory neurons: 1496.8" "Cell type enhanced" "Detected in all" "mammillary body: 12327.0;midbrain-derived inhibitory: 8295.9" "Cancer enriched" "Detected in some" 4 "Kidney Chromophobe (TCGA): 5.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.6" "Lineage enriched" "Detected in single" 8 "B-cells: 1.6" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.6" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Melanocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031019 Uncertain NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 69: Neurons - Neuronal signaling" "HPA031019: AB_10601653" "unprognostic (2.63e-2)" "unprognostic (9.73e-2)" "unprognostic (1.55e-3)" "unprognostic (5.17e-2)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (2.38e-2)" GAP43 "B-50, GAP-43, PP46" ENSG00000172020 "Growth associated protein 43" P17677 3 115623510-115721490 "Plasma proteins, Predicted intracellular proteins, Transporters" "Differentiation, Growth regulation, Neurogenesis" "Calmodulin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 31 "brain: 427.6" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 261.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 45 "Glioblastoma Multiforme (TCGA): 579.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "Neuroblastoma: 120.6" "Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts, Minor Salivary Gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004417, HPA013392, HPA015600, CAB078783" Enhanced Supported Enhanced "Plasma membrane" NA NA 18000 "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 2 "Plasma membrane" "CAB004417: AB_627660, CAB078783: AB_2620096, HPA013392: AB_1849468, HPA015600: AB_1849466" "unprognostic (1.02e-1)" "unprognostic (5.11e-2)" "unprognostic (1.05e-3)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.91e-1)" "unprognostic (1.91e-1)" "unprognostic (6.80e-2)" "unprognostic (3.98e-3)" "unprognostic (4.18e-2)" "unprognostic (3.42e-2)" "unprognostic (4.79e-2)" "unprognostic (6.91e-2)" "unprognostic (2.79e-2)" GBX2 ENSG00000168505 "Gastrulation brain homeobox 2" P52951 2 236165236-236168386 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "brain: 2.7" "Cell type enhanced" "Detected in some" "Early spermatids: 1.1;Late spermatids: 2.1;Oocytes: 1.5;Pancreatic endocrine cells: 1.7" "Cell type enhanced" "Detected in some" "bergmann glia: 5.9;ependymal cell: 3.6;thalamic excitatory: 13.9" "Group enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 2.7;Testicular Germ Cell Tumor (TCGA): 10.6" "Region enhanced" "Detected in many" "thalamus: 31.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 11.1" "Region enhanced" "Detected in single" "thalamus: 1.3" "Group enriched" "Detected in some" 4 "midbrain: 3.3;pons: 3.5;thalamus: 8.2" HPA067809 Approved Nucleoplasm Yes NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA067809: AB_2685900" "unprognostic (9.29e-3)" "unprognostic (1.21e-2)" "unprognostic (3.79e-2)" GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.0;retina: 17.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 19.0;Cone photoreceptor cells: 10.2;Fibroblasts: 25.6;Horizontal cells: 7.6;Lymphatic endothelial cells: 8.4;Rod photoreceptor cells: 27.4" "Cell type enhanced" "Detected in many" "bergmann glia: 44.6;midbrain-derived inhibitory: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 24 "Bone cancer: 13.5" "Breast - Fibroblasts, Skin - Fibroblast_2, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" Cytokine NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 53: Fibroblasts - ECM organization" Vesicles "HPA015498: AB_1849584" "unprognostic (3.16e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (2.93e-5)" "unprognostic (1.71e-2)" "unprognostic (8.76e-2)" "unprognostic (3.68e-1)" "unprognostic (2.42e-1)" "unprognostic (1.57e-3)" GDNF "ATF1, ATF2, HFB1-GDNF" ENSG00000168621 "Glial cell derived neurotrophic factor" P39905 5 37812677-37840041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes, Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 7.9;skeletal muscle: 9.7" "Cell type enriched" "Detected in some" 43 "Skeletal myocytes: 108.3" "Cell type enhanced" "Detected in some" "eccentric medium spiny neuron: 5.5;thalamic excitatory: 7.3;upper rhombic lip: 6.5" "Cancer enhanced" "Detected in some" "Skin Cuteneous Melanoma (TCGA): 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 20.0" "Heart muscle - Fibroblasts" "Region enhanced" "Detected in single" "basal ganglia: 2.8" "Low region specificity" "Detected in some" "CAB005210, HPA070283" Supported Approved Nucleoplasm,Vesicles "Secreted in other tissues" "Growth factor" NA NA "Cluster 79: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 2: Skeletal myocytes - Muscle contraction" 3 Vesicles Nucleoplasm "CAB005210: AB_2247684, HPA070283: AB_2686246" "unprognostic (1.21e-1)" "potential prognostic favorable (5.65e-4)" "unprognostic (7.72e-2)" "unprognostic (1.62e-3)" "unprognostic (6.19e-2)" "unprognostic (8.67e-3)" "unprognostic (1.45e-1)" "unprognostic (3.25e-2)" "unprognostic (9.47e-2)" GDPD5 "GDE2, PP1665" ENSG00000158555 "Glycerophosphodiester phosphodiesterase domain containing 5" Q8WTR4 11 75434640-75525941 "Enzymes, Predicted membrane proteins" "Lipid metabolism, Neurogenesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 113.8;retina: 80.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 54.8;Cone photoreceptor cells: 112.1;Early spermatids: 39.8;Late spermatids: 167.8;Rod photoreceptor cells: 83.8;Syncytiotrophoblasts: 61.5" "Cell type enhanced" "Detected in many" "fibroblast: 44.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.7" "Group enriched" "Detected in many" 6 "granulocytes: 7.7;T-cells: 2.0" "Low cancer specificity" "Detected in many" "Liver - Vascular Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065257, HPA066762, HPA069281" Uncertain Approved "Golgi apparatus" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 63: Late spermatids - Spermatogenesis" 3 "Golgi apparatus" "HPA065257: AB_2685447, HPA066762: AB_2685715, HPA069281: AB_2686107" "unprognostic (1.07e-1)" "unprognostic (5.42e-2)" "potential prognostic favorable (1.14e-4)" "unprognostic (7.41e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-2)" "unprognostic (2.15e-1)" "unprognostic (4.77e-3)" "unprognostic (9.94e-3)" "unprognostic (3.89e-2)" "unprognostic (1.79e-3)" "unprognostic (9.74e-2)" "unprognostic (1.65e-3)" "unprognostic (1.58e-3)" "unprognostic (6.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.69e-1)" "unprognostic (2.30e-2)" "unprognostic (2.41e-1)" "unprognostic (2.62e-1)" "unprognostic (3.57e-1)" "unprognostic (2.09e-2)" "unprognostic (2.84e-2)" "unprognostic (1.79e-1)" "unprognostic (7.46e-2)" "unprognostic (5.70e-3)" "unprognostic (1.63e-1)" "unprognostic (8.46e-2)" "unprognostic (6.71e-2)" "potential prognostic unfavorable (6.00e-4)" "unprognostic (7.30e-2)" GPR153 PGR1 ENSG00000158292 "G protein-coupled receptor 153" Q6NV75 1 6247353-6261098 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.3;Horizontal cells: 46.6;Intestinal goblet cells: 64.3" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 36.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Pituitary gland - Lactotropes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007159 Approved NA NA "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA007159: AB_1849268" "unprognostic (5.41e-2)" "unprognostic (1.90e-2)" "unprognostic (1.24e-1)" "unprognostic (1.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.07e-1)" "unprognostic (6.66e-3)" "unprognostic (5.81e-2)" "unprognostic (7.74e-2)" "unprognostic (2.14e-1)" "unprognostic (2.79e-3)" "unprognostic (1.89e-1)" "unprognostic (4.15e-2)" "unprognostic (1.01e-1)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (4.09e-2)" "unprognostic (2.45e-2)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (2.07e-2)" "unprognostic (1.35e-1)" "unprognostic (3.92e-2)" "unprognostic (2.80e-2)" "unprognostic (3.26e-2)" "unprognostic (2.01e-1)" "unprognostic (6.19e-2)" "unprognostic (1.59e-1)" "unprognostic (1.91e-1)" "unprognostic (1.30e-1)" "unprognostic (9.86e-2)" "unprognostic (2.72e-2)" GPR161 RE2 ENSG00000143147 "G protein-coupled receptor 161" Q8N6U8 1 168079542-168137667 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 40.1;smooth muscle: 26.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 18.3;Horizontal cells: 44.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Outer root sheath cells, Spleen - Fibroblast_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015576, HPA072047" Uncertain Approved "Primary cilium,Primary cilium transition zone" NA No "Cluster 62: Connective tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 9: Endometrial stromal cells - Transcription" 6 "Primary cilium" "Primary cilium transition zone" "HPA015576: AB_1849283, HPA072047: AB_2686484" "unprognostic (1.77e-1)" "unprognostic (2.64e-1)" "unprognostic (1.24e-1)" "unprognostic (2.02e-2)" "unprognostic (1.40e-2)" "unprognostic (1.48e-1)" "unprognostic (2.13e-1)" "unprognostic (3.71e-3)" "unprognostic (1.49e-1)" "unprognostic (1.17e-1)" "unprognostic (1.23e-1)" "unprognostic (3.88e-2)" "unprognostic (2.22e-3)" "unprognostic (1.14e-1)" "unprognostic (1.16e-2)" "unprognostic (3.32e-2)" "unprognostic (2.40e-1)" "unprognostic (9.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (8.70e-3)" "unprognostic (1.65e-1)" "unprognostic (2.02e-2)" "unprognostic (4.14e-1)" "unprognostic (3.87e-3)" "unprognostic (4.29e-2)" "unprognostic (3.98e-2)" "unprognostic (3.08e-2)" "unprognostic (1.95e-1)" "unprognostic (3.84e-1)" GRID2IP ENSG00000215045 "Grid2 interacting protein" A4D2P6 7 6496778-6551461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Collecting duct cells: 1.9;Excitatory neurons: 2.7;Inhibitory neurons: 2.8;Oligodendrocyte precursor cells: 4.2;Rod photoreceptor cells: 1.9" "Cell type enriched" "Detected in many" 5 "thalamic excitatory: 60.1" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in all" "thalamus: 72.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 2.5" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other)" "Group enriched" "Detected in many" 5 "cerebellum: 22.4;thalamus: 7.2" "Low region specificity" "Detected in all" HPA045381 Approved "Plasma membrane" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 69: Neurons - Neuronal signaling" 1 "Plasma membrane" "HPA045381: AB_10962495" "unprognostic (2.44e-1)" "unprognostic (1.45e-1)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" GRIN2D "EB11, GluN2D, NMDAR2D, NR2D" ENSG00000105464 "Glutamate ionotropic receptor NMDA type subunit 2D" O15399 19 48393668-48444931 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.5" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 35.0;Oligodendrocyte precursor cells: 14.6" "Cell type enhanced" "Detected in many" "CGE interneuron: 74.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009006 Approved NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 69: Neurons - Neuronal signaling" "CAB009006: AB_2279191" "potential prognostic unfavorable (3.80e-4)" "unprognostic (8.20e-2)" "unprognostic (2.25e-1)" "unprognostic (4.50e-1)" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.34e-1)" "unprognostic (3.89e-1)" "unprognostic (3.39e-1)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (1.49e-1)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (8.74e-5)" "unprognostic (9.08e-2)" "unprognostic (1.06e-1)" "unprognostic (9.50e-2)" "unprognostic (6.27e-3)" "unprognostic (2.95e-1)" "unprognostic (2.33e-2)" "unprognostic (8.32e-2)" "unprognostic (2.44e-1)" GRINA "HNRGW, LFG1, NMDARA1, TMBIM3" ENSG00000178719 "Glutamate ionotropic receptor NMDA type subunit associated protein 1" Q7Z429 8 143990056-143993415 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 428.6;monocytes: 329.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036980, HPA036981" Approved Approved "Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 25: Non-specific - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 14: Langerhans cells - Innate immune response" 6 "Nucleoli fibrillar center" Cytosol "HPA036980: AB_10696791, HPA036981: AB_10962980" "unprognostic (4.51e-2)" "unprognostic (3.41e-3)" "unprognostic (2.05e-1)" "unprognostic (1.27e-3)" "unprognostic (9.48e-2)" "unprognostic (1.99e-2)" "unprognostic (1.16e-1)" "unprognostic (4.66e-2)" "unprognostic (2.14e-3)" "unprognostic (2.33e-1)" "unprognostic (3.57e-2)" "unprognostic (6.45e-2)" "unprognostic (1.55e-2)" "unprognostic (3.29e-2)" "unprognostic (6.59e-2)" "unprognostic (3.62e-2)" "unprognostic (7.41e-2)" "unprognostic (6.84e-2)" "unprognostic (1.61e-2)" "unprognostic (7.15e-2)" "unprognostic (8.99e-2)" "unprognostic (1.17e-1)" "unprognostic (1.32e-3)" "unprognostic (5.39e-2)" "unprognostic (3.27e-2)" "unprognostic (2.69e-1)" "unprognostic (3.42e-1)" "unprognostic (1.49e-1)" "unprognostic (1.89e-1)" "unprognostic (5.27e-2)" "unprognostic (5.74e-3)" GRIP2 KIAA1719 ENSG00000144596 "Glutamate receptor interacting protein 2" Q9C0E4 3 14489107-14556075 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 12.8;skeletal muscle: 34.5;tongue: 12.0" "Cell type enhanced" "Detected in many" "Horizontal cells: 25.8;Inhibitory neurons: 85.4;Ovarian stromal cells: 17.4;Rod photoreceptor cells: 28.5;Skeletal myocytes: 27.3" "Cell type enhanced" "Detected in many" "MGE interneuron: 143.5;midbrain-derived inhibitory: 291.2;vascular associated smooth muscle cell: 177.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.0;Rhabdoid: 5.0" "Heart muscle - Cardiomyocytes, Stomach - Parietal cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035673 Approved Cytosol NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 65: Neurons - Synaptic function" 1 Cytosol "HPA035673: AB_10669776" "unprognostic (2.52e-1)" "unprognostic (7.34e-2)" "unprognostic (1.57e-1)" "unprognostic (6.24e-3)" "unprognostic (1.56e-1)" "unprognostic (2.17e-1)" "unprognostic (1.90e-2)" "unprognostic (2.32e-1)" GRWD1 "GRWD, RRB1, WDR28" ENSG00000105447 "Glutamate rich WD repeat containing 1" Q9BQ67 19 48445841-48457022 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042643, HPA055680" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 30: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 47 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA042643: AB_10795510, HPA055680: AB_2682884" "unprognostic (1.24e-1)" "unprognostic (8.75e-2)" "unprognostic (2.66e-2)" "unprognostic (3.66e-3)" "unprognostic (7.05e-2)" "unprognostic (8.51e-2)" "unprognostic (2.45e-1)" "unprognostic (2.20e-1)" "unprognostic (1.93e-2)" "unprognostic (3.04e-2)" "potential prognostic favorable (1.07e-6)" "unprognostic (2.00e-2)" "unprognostic (2.85e-1)" "unprognostic (6.20e-3)" "potential prognostic unfavorable (4.67e-4)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (6.74e-2)" "unprognostic (1.15e-1)" "unprognostic (2.18e-1)" "unprognostic (6.47e-2)" "unprognostic (1.49e-1)" "unprognostic (6.21e-2)" "unprognostic (1.96e-1)" "unprognostic (1.63e-2)" "unprognostic (9.15e-2)" "unprognostic (4.66e-2)" "unprognostic (8.59e-3)" "unprognostic (1.86e-1)" "unprognostic (2.90e-1)" "unprognostic (9.88e-2)" "unprognostic (8.49e-2)" GSG1L "KTSR5831, MGC18079, PRO19651" ENSG00000169181 "GSG1 like" Q6UXU4 16 27787528-28063714 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 20.9;heart muscle: 22.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 25.1;Horizontal cells: 18.9;Oligodendrocyte precursor cells: 84.0" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 247.8" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 19.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 4.9" "Colon - Colon enteroendocrine cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014479 Enhanced NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 "HPA014479: AB_2247974" "unprognostic (2.93e-2)" "unprognostic (1.03e-1)" "unprognostic (2.44e-1)" "unprognostic (6.04e-2)" "unprognostic (1.88e-1)" "unprognostic (2.83e-2)" "unprognostic (1.45e-3)" "unprognostic (5.38e-2)" HAND1 "bHLHa27, eHand, Hxt, Thing1" ENSG00000113196 "Heart and neural crest derivatives expressed 1" O96004 5 154474972-154478227 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 23.6;intestine: 63.9" "Group enriched" "Detected in some" 10 "Cardiomyocytes: 15.0;Fibroblasts: 12.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 5.2" "Region enriched" "Detected in single" 4 "thalamus: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Neuroblastoma: 88.8;testis cancer: 195.7" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040925, HPA075313" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 45: Intestine - Digestion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 50: Connective tissue cells - ECM organization" 5 Nucleoplasm "Nuclear membrane, Nuclear bodies" "HPA040925: AB_10796563, HPA075313: " "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (5.41e-2)" HCN4 ENSG00000138622 "Hyperpolarization activated cyclic nucleotide gated potassium channel 4" Q9Y3Q4 15 73319859-73368958 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Brugada syndrome, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 8.1;testis: 7.0" "Group enriched" "Detected in some" 4 "Early spermatids: 16.8;Late spermatids: 53.8" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 26.4" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 1.8" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073174 Approved NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 11: Late spermatids - Unknown function" 5 "HPA073174: " "unprognostic (6.74e-2)" HEBP2 "C6orf34, SOUL" ENSG00000051620 "Heme binding protein 2" Q9Y5Z4 6 138403531-138422197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 613.2;Suprabasal keratinocytes: 636.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016928 Approved NA NA 800000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 59: Suprabasal keratinocytes - Cornification" 5 "HPA016928: AB_1850572" "unprognostic (8.40e-2)" "unprognostic (1.59e-2)" "unprognostic (2.94e-1)" "unprognostic (2.96e-2)" "unprognostic (6.00e-2)" "unprognostic (3.28e-1)" "unprognostic (1.02e-2)" "unprognostic (3.27e-3)" "unprognostic (4.08e-3)" "unprognostic (2.13e-1)" "unprognostic (1.21e-1)" "unprognostic (5.22e-2)" "unprognostic (2.37e-2)" "unprognostic (1.05e-1)" "unprognostic (1.36e-2)" "unprognostic (6.23e-3)" "unprognostic (5.48e-2)" "unprognostic (2.83e-1)" "unprognostic (1.08e-1)" "unprognostic (4.23e-2)" "unprognostic (5.87e-2)" "unprognostic (1.65e-2)" "unprognostic (1.09e-1)" "unprognostic (2.38e-1)" "unprognostic (3.21e-1)" "unprognostic (3.39e-3)" "unprognostic (1.66e-1)" "unprognostic (1.28e-2)" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (5.26e-2)" HELT "bHLHb44, HCM1228, HESL, MEGANE, Mgn" ENSG00000187821 "Helt bHLH transcription factor" A6NFD8 4 185018490-185020953 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "kidney: 1.4" "Group enriched" "Detected in some" 13 "Alveolar cells type 1: 2.1;Distal tubular cells: 6.1" "Cell type enriched" "Detected in single" 5 "choroid plexus epithelial cell: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036188, HPA036189" Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 39: Non-specific - Basic cellular processes" "HPA036188: AB_10672237, HPA036189: AB_2674997" HES3 bHLHb43 ENSG00000173673 "Hes family bHLH transcription factor 3" Q5TGS1 1 6244179-6245578 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Testicular Germ Cell Tumor (TCGA): 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 30 "cerebellum: 34.8" "Low region specificity" "Detected in some" "HPA047927, HPA072697" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 34: Testis cancer - Unknown function" Nucleoplasm "HPA047927: AB_2680213, HPA072697: " "unprognostic (2.37e-1)" HIRA "DGCR1, TUP1, TUPLE1" ENSG00000100084 "Histone cell cycle regulator" P54198 22 19330698-19447450 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 54.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 48.0;Inhibitory neurons: 49.0;Microglial cells: 36.7;Oligodendrocyte precursor cells: 35.4;Oligodendrocytes: 42.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB039243, CAB039244, HPA050714, HPA052902" Enhanced Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 65: Neurons - Synaptic function" 38 Nucleoplasm "CAB039243: , CAB039244: , HPA050714: AB_2681219, HPA052902: AB_2681984" "unprognostic (3.24e-1)" "unprognostic (1.67e-3)" "unprognostic (3.47e-1)" "unprognostic (2.52e-1)" "unprognostic (8.41e-3)" "unprognostic (5.04e-2)" "unprognostic (6.77e-2)" "potential prognostic favorable (9.86e-4)" "unprognostic (3.04e-1)" "unprognostic (1.45e-1)" "potential prognostic favorable (2.54e-7)" "unprognostic (1.96e-3)" "potential prognostic favorable (6.90e-4)" "unprognostic (4.97e-2)" "unprognostic (3.08e-1)" "unprognostic (1.63e-1)" "unprognostic (5.56e-2)" "unprognostic (3.90e-2)" "unprognostic (8.31e-3)" "unprognostic (1.93e-1)" "unprognostic (5.23e-2)" "unprognostic (1.85e-2)" "unprognostic (8.32e-2)" "unprognostic (2.99e-1)" "unprognostic (1.47e-3)" "unprognostic (2.95e-2)" "unprognostic (6.94e-2)" "unprognostic (1.18e-1)" "unprognostic (2.42e-1)" "unprognostic (2.85e-1)" "unprognostic (5.45e-2)" HRH3 GPCR97 ENSG00000101180 "Histamine receptor H3" Q9Y5N1 20 62214960-62220278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "brain: 54.1" "Group enriched" "Detected in some" 4 "Horizontal cells: 15.7;Inhibitory neurons: 22.7" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 122.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "lung cancer: 5.0;Neuroblastoma: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" 1 HTR7 5-HT7 ENSG00000148680 "5-hydroxytryptamine receptor 7" P34969 10 90740823-90858039 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "parathyroid gland: 12.7;testis: 8.5" "Cell type enhanced" "Detected in some" "Early spermatids: 9.2;Excitatory neurons: 5.7;Inhibitory neurons: 23.4;Macrophages: 3.6;Spermatocytes: 10.9" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 134.7;mammillary body: 335.5" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 3.1;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.5;Head and Neck Squamous Cell Carcinoma (TCGA): 5.0;Lung Squamous Cell Carcinoma (TCGA): 2.5;Testicular Germ Cell Tumor (TCGA): 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.4" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB022708, HPA065367, HPA073617" Approved Supported Approved "Nucleoplasm,Nuclear speckles,Plasma membrane,Primary cilium,Cytosol" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 8: Neurons - Neuronal signaling" 1 "Plasma membrane" "Nucleoplasm, Nuclear speckles, Primary cilium, Cytosol" "CAB022708: , HPA065367: , HPA073617: AB_2732228" "unprognostic (1.43e-1)" "unprognostic (3.78e-2)" "unprognostic (1.54e-3)" "unprognostic (8.63e-2)" "unprognostic (1.48e-2)" "unprognostic (9.57e-2)" "unprognostic (1.76e-1)" "unprognostic (1.58e-2)" "unprognostic (3.13e-2)" "unprognostic (1.50e-1)" IGSF22 "FLJ37794, IGFN2" ENSG00000179057 "Immunoglobulin superfamily member 22" Q8N9C0 11 18704312-18726230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.0;skin 1: 1.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 21.4;Distal tubular cells: 21.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Rhabdoid: 1.3" "Skin - Keratinocyte (granular)" "CAB026459, HPA037851" Uncertain Approved Mitochondria NA NA "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB026459: , HPA037851: " "unprognostic (9.66e-2)" "unprognostic (3.88e-1)" IKBKE "IKK-i, IKKE, KIAA0151" ENSG00000263528 "Inhibitor of nuclear factor kappa B kinase subunit epsilon" Q14164 1 206470476-206496889 "Enzymes, Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 39.1;Ionocytes: 24.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 25.1;leukocyte: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015788, CAB025983" Approved Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 35: Respiratory epithelial cells - Unknown function" 51 Cytosol "CAB025983: , HPA015788: AB_1851566" "unprognostic (2.93e-2)" "unprognostic (8.24e-2)" "potential prognostic favorable (2.26e-4)" "unprognostic (8.61e-2)" "unprognostic (1.70e-1)" "unprognostic (2.87e-1)" "unprognostic (6.56e-3)" "unprognostic (2.63e-1)" "unprognostic (5.93e-3)" "potential prognostic unfavorable (3.30e-6)" "unprognostic (3.89e-2)" "unprognostic (7.42e-2)" "unprognostic (2.84e-3)" "unprognostic (2.13e-2)" "unprognostic (9.92e-2)" "unprognostic (6.89e-3)" "unprognostic (9.25e-2)" "unprognostic (6.77e-2)" "unprognostic (2.45e-1)" "unprognostic (1.69e-1)" "unprognostic (2.35e-1)" "unprognostic (1.29e-1)" "unprognostic (1.05e-1)" "unprognostic (1.17e-2)" "unprognostic (2.77e-2)" "unprognostic (2.62e-2)" "unprognostic (7.46e-3)" "unprognostic (3.38e-1)" IL2RB "CD122, IL15RB" ENSG00000100385 "Interleukin 2 receptor subunit beta" P14784 22 37118666-37175118 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.4;lymphoid tissue: 48.0" "Group enriched" "Detected in many" 7 "Extravillous trophoblasts: 97.1;NK-cells: 299.6;T-cells: 95.9" "Cell type enriched" "Detected in single" 131 "leukocyte: 108.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "gdT-cell: 49.8;NK-cell: 184.0" "Group enriched" "Detected in many" 30 "NK-cells: 184.0;T-cells: 49.8" "Cancer enriched" "Detected in some" 8 "lymphoma: 69.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Low region specificity" "Detected in many" HPA062657 Enhanced NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 9 "HPA062657: AB_2684822" "unprognostic (3.48e-2)" "unprognostic (4.47e-3)" "unprognostic (1.98e-3)" "unprognostic (3.00e-3)" "unprognostic (1.07e-1)" "unprognostic (8.58e-3)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (2.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.54e-1)" "unprognostic (2.67e-2)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (3.82e-1)" "unprognostic (2.13e-2)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (6.57e-2)" "unprognostic (2.43e-1)" "unprognostic (9.56e-2)" "unprognostic (9.04e-2)" "unprognostic (2.67e-1)" "unprognostic (1.42e-1)" "unprognostic (2.83e-1)" "unprognostic (1.05e-1)" "unprognostic (1.91e-2)" "potential prognostic favorable (6.40e-4)" "unprognostic (9.05e-2)" "unprognostic (1.03e-1)" "unprognostic (1.12e-2)" "unprognostic (3.12e-1)" ILDR2 C1orf32 ENSG00000143195 "Immunoglobulin like domain containing receptor 2" Q71H61 1 166895711-166975540 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;retina: 10.3;testis: 8.5" "Cell type enhanced" "Detected in some" "Astrocytes: 21.7;Excitatory neurons: 43.4;Muller glia cells: 74.3;Oligodendrocyte precursor cells: 90.1;Sertoli cells: 21.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 4.6" "Adipose visceral - Mesothelial cells, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012545, HPA012815" Uncertain Approved "Plasma membrane" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 10: Muller glia cells - Visual perception" 1 "Plasma membrane" "HPA012545: AB_2126894, HPA012815: " "potential prognostic unfavorable (2.04e-4)" "unprognostic (2.43e-2)" "unprognostic (1.79e-2)" "potential prognostic favorable (1.54e-5)" "unprognostic (1.41e-2)" "unprognostic (1.63e-2)" "unprognostic (1.35e-1)" "unprognostic (4.27e-3)" "unprognostic (1.27e-1)" INPP4B ENSG00000109452 "Inositol polyphosphate-4-phosphatase type II B" O15327 4 142023160-142847432 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 150.5;Early spermatids: 156.0;Excitatory neurons: 189.6;Inhibitory neurons: 589.5;Late spermatids: 291.2" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 4297.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 30.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037681, HPA037682" Approved Approved Centrosome NA NA 3900 "Cluster 11: T-cells - Unknown function" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Neurons - Neuronal signaling" 1 Centrosome "HPA037681: AB_10670389, HPA037682: AB_10671377" "unprognostic (3.32e-2)" "unprognostic (1.23e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-2)" "unprognostic (7.98e-2)" "unprognostic (8.50e-2)" "unprognostic (2.58e-1)" "unprognostic (1.94e-1)" "unprognostic (2.74e-2)" "unprognostic (4.29e-2)" "validated prognostic favorable (1.09e-6)" "validated prognostic favorable (3.37e-4)" "unprognostic (1.13e-1)" "unprognostic (1.75e-1)" "unprognostic (1.24e-2)" "unprognostic (6.51e-3)" "unprognostic (5.05e-3)" "potential prognostic unfavorable (1.40e-5)" "unprognostic (3.48e-1)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (4.59e-5)" "unprognostic (3.91e-2)" "unprognostic (8.58e-2)" "unprognostic (3.34e-2)" "unprognostic (1.81e-1)" "unprognostic (9.38e-2)" "unprognostic (2.50e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" "unprognostic (5.30e-2)" INSYN2A "C10orf141, FAM196A, FLJ45557, INSYN2" ENSG00000188916 "Inhibitory synaptic factor 2A" Q6ZSG2 10 127135426-127196591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;retina: 1.5" "Cell type enhanced" "Detected in some" "Astrocytes: 11.5;Bipolar cells: 11.0;dendritic cells: 15.0;Inhibitory neurons: 17.7;Leydig cells: 14.9;Oligodendrocyte precursor cells: 34.0;Oligodendrocytes: 23.5;Peritubular cells: 12.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Breast Invasive Carcinoma (TCGA): 5.0;Glioblastoma Multiforme (TCGA): 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.1" "Breast - Breast glandular cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035898, HPA035899" Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Neurons - Neuronal signaling" 2 "HPA035898: AB_10964352, HPA035899: AB_10961723" "unprognostic (1.18e-1)" "unprognostic (9.50e-2)" "unprognostic (3.21e-1)" "unprognostic (2.75e-2)" "unprognostic (1.07e-1)" "unprognostic (6.51e-3)" IPO9 "FLJ10402, Imp9" ENSG00000198700 "Importin 9" Q96P70 1 201829149-201884291 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018249, HPA020866" Supported Nucleoplasm,Cytosol NA NA 100000 "Cluster 25: Non-specific - Unknown function" "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" 40 Cytosol Nucleoplasm "HPA018249: , HPA020866: " "unprognostic (8.78e-2)" "unprognostic (1.84e-1)" "unprognostic (2.12e-1)" "unprognostic (1.05e-3)" "unprognostic (1.85e-1)" "unprognostic (1.00e-1)" "unprognostic (2.61e-1)" "unprognostic (8.97e-2)" "unprognostic (1.73e-1)" "unprognostic (7.20e-2)" "unprognostic (2.56e-2)" "unprognostic (4.10e-1)" "unprognostic (1.27e-3)" "potential prognostic unfavorable (1.21e-5)" "unprognostic (1.16e-2)" "unprognostic (4.36e-3)" "unprognostic (1.69e-2)" "unprognostic (1.97e-2)" "unprognostic (2.27e-1)" "unprognostic (1.72e-1)" "unprognostic (3.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.47e-3)" "unprognostic (1.86e-1)" "unprognostic (2.54e-1)" "unprognostic (8.88e-2)" "unprognostic (3.41e-2)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" "unprognostic (3.72e-1)" "unprognostic (9.82e-3)" ISM1 "bA149I18.1, C20orf82" ENSG00000101230 "Isthmin 1" B1AKI9 20 13221274-13300651 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 43.1" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 23.6;Fibroblasts: 17.6;Microglial cells: 8.1;Smooth muscle cells: 6.3" "Cell type enriched" "Detected in many" 4 "fibroblast: 293.6" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 19.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Cancer enhanced" "Detected in many" "Kidney cancer: 4.8" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 18.7" "Secreted in other tissues" "No annotated function" NA NA 7800 "Cluster 51: Thyroid gland - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 53: Fibroblasts - ECM organization" "unprognostic (9.70e-2)" "unprognostic (2.11e-1)" "unprognostic (2.03e-1)" "unprognostic (5.18e-2)" "potential prognostic unfavorable (4.94e-4)" "unprognostic (3.21e-1)" "unprognostic (1.98e-1)" "unprognostic (5.59e-2)" "unprognostic (1.14e-3)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (9.83e-4)" "unprognostic (1.83e-1)" "unprognostic (2.52e-2)" "unprognostic (2.18e-1)" "unprognostic (2.48e-3)" "unprognostic (4.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (5.92e-4)" "unprognostic (4.30e-2)" "unprognostic (2.19e-1)" "unprognostic (2.16e-1)" "unprognostic (2.48e-2)" "unprognostic (2.13e-1)" "unprognostic (6.87e-3)" "unprognostic (5.11e-2)" "unprognostic (1.16e-1)" KAT2A "GCN5, GCN5L2, PCAF-b" ENSG00000108773 "Lysine acetyltransferase 2A" Q92830 17 42113111-42121367 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 80.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048958 Uncertain NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 84 "HPA048958: AB_2680571" "unprognostic (1.52e-1)" "unprognostic (7.59e-3)" "unprognostic (2.89e-2)" "unprognostic (3.43e-2)" "unprognostic (8.53e-3)" "unprognostic (2.20e-2)" "unprognostic (1.99e-1)" "unprognostic (1.13e-2)" "unprognostic (2.90e-2)" "potential prognostic unfavorable (7.63e-5)" "unprognostic (1.36e-2)" "unprognostic (2.52e-1)" "unprognostic (3.08e-3)" "potential prognostic unfavorable (4.33e-4)" "unprognostic (2.19e-1)" "unprognostic (6.10e-3)" "unprognostic (2.45e-3)" "unprognostic (1.72e-1)" "unprognostic (2.69e-1)" "unprognostic (7.91e-2)" "unprognostic (1.67e-1)" "unprognostic (9.45e-2)" "unprognostic (1.17e-2)" "unprognostic (1.29e-2)" "potential prognostic favorable (1.27e-4)" "unprognostic (8.96e-2)" "unprognostic (2.86e-2)" "unprognostic (4.71e-3)" "unprognostic (7.31e-2)" "unprognostic (4.18e-2)" "unprognostic (2.88e-1)" KCND3 "KSHIVB, Kv4.3, SCA19, SCA22" ENSG00000171385 "Potassium voltage-gated channel subfamily D member 3" Q9UK17 1 111770662-111989668 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.6;Cardiomyocytes: 36.9;Excitatory neurons: 102.1;Hepatocytes: 32.7;Horizontal cells: 40.9;Inhibitory neurons: 84.6;Late spermatids: 34.4;Oligodendrocyte precursor cells: 42.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.6" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029452 Approved NA NA "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 4 "HPA029452: AB_10602239" "unprognostic (2.39e-3)" "unprognostic (9.43e-3)" "unprognostic (1.18e-1)" "unprognostic (6.72e-2)" "unprognostic (1.88e-1)" "unprognostic (1.83e-1)" "unprognostic (1.51e-1)" "unprognostic (1.34e-3)" "unprognostic (2.94e-1)" "unprognostic (1.68e-1)" "unprognostic (5.41e-3)" "unprognostic (2.58e-3)" "unprognostic (1.82e-1)" "unprognostic (4.59e-3)" "unprognostic (9.59e-3)" "unprognostic (9.40e-3)" "unprognostic (4.55e-2)" "unprognostic (9.48e-2)" "unprognostic (4.74e-2)" "unprognostic (2.23e-2)" "unprognostic (5.09e-2)" "unprognostic (1.23e-2)" "unprognostic (1.50e-1)" "unprognostic (3.62e-1)" KCNQ3 "EBN2, Kv7.3" ENSG00000184156 "Potassium voltage-gated channel subfamily Q member 3" O43525 8 132120859-132481095 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 16.1" "Group enriched" "Detected in many" 4 "Excitatory neurons: 484.5;Inhibitory neurons: 464.3;Microglial cells: 479.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 2585.5" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 5.0;Thyroid Carcinoma (TCGA): 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 65: Neurons - Synaptic function" 1 "unprognostic (2.08e-1)" "unprognostic (1.12e-3)" "unprognostic (3.22e-1)" "unprognostic (6.14e-2)" "unprognostic (2.55e-2)" "unprognostic (1.38e-1)" "unprognostic (1.94e-1)" "unprognostic (5.54e-3)" "unprognostic (8.75e-3)" "unprognostic (1.34e-1)" "unprognostic (1.05e-1)" "unprognostic (1.89e-2)" "unprognostic (9.82e-2)" KIAA0319 NMIG ENSG00000137261 KIAA0319 Q5VV43 6 24544104-24646191 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.4;pituitary gland: 4.0" "Group enriched" "Detected in some" 9 "Astrocytes: 113.3;Early spermatids: 52.2;Excitatory neurons: 124.8;Inhibitory neurons: 69.6;Late spermatids: 100.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enhanced" "Detected in single" "granulocytes: 1.6" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015607, HPA076313" Enhanced Supported Approved Vesicles "Secreted in brain" "Developmental protein" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA015607: AB_1852299, HPA076313: AB_2732308" "unprognostic (7.62e-2)" "unprognostic (9.61e-3)" "unprognostic (5.34e-2)" "unprognostic (8.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.99e-3)" "unprognostic (2.87e-1)" "unprognostic (2.78e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-3)" "unprognostic (7.01e-2)" "unprognostic (1.51e-2)" KIAA0319L "AAVR, KIAA1837" ENSG00000142687 "KIAA0319 like" Q8IZA0 1 35393883-35557950 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072692 Supported Supported "Nucleoli,Golgi apparatus" NA NA 530000 "Cluster 28: Neutrophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 16: Intestinal goblet cells - Mucin production" 6 "Golgi apparatus" Nucleoli "HPA072692: AB_2686549" "unprognostic (9.17e-2)" "unprognostic (2.15e-1)" "unprognostic (2.96e-1)" "unprognostic (3.86e-3)" "unprognostic (1.05e-3)" "unprognostic (2.30e-1)" "unprognostic (4.57e-2)" "unprognostic (1.18e-1)" "unprognostic (2.35e-1)" "unprognostic (1.13e-1)" "potential prognostic favorable (5.92e-6)" "unprognostic (8.88e-2)" "unprognostic (6.22e-2)" "potential prognostic unfavorable (1.18e-5)" "unprognostic (7.12e-2)" "unprognostic (7.17e-2)" "unprognostic (1.69e-2)" "unprognostic (1.05e-1)" "unprognostic (2.64e-1)" "unprognostic (4.47e-2)" "unprognostic (2.88e-1)" "unprognostic (9.33e-2)" "unprognostic (3.84e-1)" "unprognostic (2.27e-1)" "unprognostic (3.35e-1)" "unprognostic (5.68e-3)" "unprognostic (9.35e-2)" "unprognostic (1.86e-1)" "unprognostic (1.95e-1)" "unprognostic (2.57e-1)" "unprognostic (1.03e-1)" KIAA1958 FLJ39294 ENSG00000165185 KIAA1958 Q8N8K9 9 112486827-112669397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 161.0;Excitatory neurons: 61.9;Inhibitory neurons: 52.4;Oligodendrocyte precursor cells: 119.8;Oligodendrocytes: 154.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Chief cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020625 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 39: Retina & Testis - Cilium" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Oligodendrocyte precursor - Unknown function" 11 "Plasma membrane, Cytosol" "HPA020625: AB_1852451" "unprognostic (1.27e-1)" "unprognostic (4.95e-3)" "unprognostic (2.35e-1)" "unprognostic (3.27e-1)" "unprognostic (1.53e-1)" "unprognostic (2.85e-2)" "unprognostic (5.10e-2)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (4.49e-2)" "validated prognostic favorable (1.47e-6)" "validated prognostic favorable (3.59e-5)" "unprognostic (1.75e-1)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (2.43e-2)" "unprognostic (5.10e-1)" "unprognostic (4.02e-1)" "unprognostic (1.07e-2)" "unprognostic (9.37e-2)" "unprognostic (2.71e-1)" "unprognostic (1.53e-1)" "unprognostic (8.41e-2)" "unprognostic (3.40e-2)" "potential prognostic favorable (9.53e-5)" "unprognostic (2.07e-2)" "unprognostic (7.63e-2)" "unprognostic (8.93e-2)" "unprognostic (3.69e-1)" "unprognostic (3.56e-2)" "unprognostic (1.30e-1)" KLHL13 "BKLHD2, FLJ10262, KIAA1309" ENSG00000003096 "Kelch like family member 13" Q9P2N7 X 117897813-118117340 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 30.3" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 28.1;Microglial cells: 29.5;Oligodendrocyte precursor cells: 96.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 7.3;plasmacytoid DC: 4.1" "Group enriched" "Detected in many" 5 "dendritic cells: 4.1;granulocytes: 7.3" "Group enriched" "Detected in many" 5 "cervical cancer: 25.8;Neuroblastoma: 103.2" "Minor Salivary Gland - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046039, HPA059901" Approved Approved Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 62: Connective tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Oligodendrocyte precursor - Unknown function" 24 Cytosol "HPA046039: AB_2679514, HPA059901: AB_2684155" "unprognostic (1.49e-1)" "unprognostic (1.39e-1)" "unprognostic (5.40e-2)" "unprognostic (1.63e-1)" "unprognostic (8.95e-2)" "unprognostic (3.11e-2)" "unprognostic (4.58e-3)" "potential prognostic favorable (5.07e-4)" "unprognostic (5.67e-2)" "unprognostic (2.07e-1)" "potential prognostic favorable (3.81e-6)" "unprognostic (1.85e-1)" "unprognostic (5.49e-3)" "unprognostic (7.94e-2)" "potential prognostic unfavorable (5.32e-4)" "unprognostic (2.36e-2)" "unprognostic (1.45e-1)" "unprognostic (1.51e-2)" "unprognostic (5.99e-3)" "unprognostic (2.50e-1)" "unprognostic (3.15e-2)" "unprognostic (8.56e-2)" "unprognostic (8.99e-2)" "unprognostic (2.59e-1)" "unprognostic (9.35e-2)" "unprognostic (4.67e-2)" "unprognostic (3.44e-2)" "potential prognostic unfavorable (8.45e-4)" "unprognostic (6.15e-2)" "unprognostic (2.82e-2)" KLHL41 "KBTBD10, Krp1, SARCOSIN" ENSG00000239474 "Kelch like family member 41" O60662 2 169509702-169526258 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 42 "skeletal muscle: 4860.2;tongue: 3340.1" "Cell type enriched" "Detected in some" 12 "Skeletal myocytes: 1749.6" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 8 "Head and Neck Squamous Cell Carcinoma (TCGA): 27.1;Prostate Adenocarcinoma (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Sarcoma: 16.3" "Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021165, HPA021753, HPA021760" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 2: Skeletal myocytes - Muscle contraction" 10 Cytosol "Nucleoplasm, Plasma membrane" "HPA021165: AB_1852087, HPA021753: AB_1852089, HPA021760: AB_1852091" "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (4.00e-3)" "potential prognostic favorable (3.34e-4)" "unprognostic (2.49e-1)" "unprognostic (2.66e-1)" "unprognostic (1.65e-3)" KRT31 "Ha-1, KRTHA1" ENSG00000094796 "Keratin 31" Q15323 17 41393721-41397608 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 275.4" "Group enriched" "Detected in some" 6 "Basal keratinocytes: 32.4;Basal squamous epithelial cells: 18.4;Glandular and luminal cells: 11.6;Oocytes: 12.5;Squamous epithelial cells: 16.7;Suprabasal keratinocytes: 19.2" "Group enriched" "Detected in some" 5 "thalamic excitatory: 7.3;upper rhombic lip: 17.1" "Cancer enriched" "Detected in single" 8 "Lung Squamous Cell Carcinoma (TCGA): 6.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes" "HPA049550, HPA055194" Enhanced Approved "Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" NA NA 260000000 "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 320 "Cytosol, Principal piece, End piece" "Equatorial segment, Mid piece" "HPA049550: AB_2680813, HPA055194: AB_2682733" "unprognostic (1.38e-2)" "unprognostic (2.73e-1)" LASP1 "Lasp-1, MLN50" ENSG00000002834 "LIM and SH3 protein 1" Q14847 17 38869859-38921770 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 588.6;Proximal enterocytes: 277.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012072, CAB022049" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 14000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" 35 "Plasma membrane, Cytosol" "Focal adhesion sites" "CAB022049: , HPA012072: AB_1852714" "unprognostic (5.01e-2)" "unprognostic (2.56e-1)" "unprognostic (5.77e-2)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (2.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.92e-1)" "unprognostic (3.46e-2)" "unprognostic (1.80e-1)" "unprognostic (6.51e-2)" "potential prognostic favorable (5.22e-5)" "unprognostic (5.25e-2)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (9.95e-5)" "unprognostic (1.48e-2)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (1.73e-2)" "unprognostic (1.47e-2)" "unprognostic (1.67e-1)" "unprognostic (7.29e-2)" "unprognostic (7.26e-2)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (1.18e-1)" "unprognostic (4.58e-2)" "unprognostic (2.75e-1)" "unprognostic (7.20e-2)" "unprognostic (1.05e-2)" "unprognostic (2.65e-1)" "unprognostic (1.70e-2)" "unprognostic (1.39e-1)" LEF1 "TCF10, TCF1ALPHA, TCF7L3" ENSG00000138795 "Lymphoid enhancer binding factor 1" Q9UJU2 4 108047545-108168956 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 28 "lymphoid tissue: 340.3" "Cell type enhanced" "Detected in many" "Melanocytes: 46.4;Microglial cells: 138.7;T-cells: 74.0" "Cell type enhanced" "Detected in many" "endothelial cell: 1148.3;pericyte: 340.2" "Cancer enriched" "Detected in many" 5 "Skin Cuteneous Melanoma (TCGA): 54.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 143.0" "Lineage enriched" "Detected in many" 4 "T-cells: 143.0" "Cancer enhanced" "Detected in many" "Leukemia: 151.1" "Adrenal gland - Adrenal cortex cells, Liver - T-cells, Skin - Inner root sheath cells, Spleen - T-cells, Testis - Early spermatids" "Region enhanced" "Detected in all" "thalamus: 22.6" "Low region specificity" "Detected in all" "HPA002087, CAB019405" Enhanced Approved Nucleoplasm NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 71: Thymus - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 7: T-cells - T-cell receptor" 23 Nucleoplasm "CAB019405: AB_823558, HPA002087: AB_1079245" "unprognostic (2.39e-1)" "unprognostic (1.94e-3)" "unprognostic (3.46e-2)" "unprognostic (3.60e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-1)" "unprognostic (3.42e-1)" "unprognostic (3.80e-3)" "unprognostic (4.92e-2)" "unprognostic (3.11e-1)" "unprognostic (2.66e-2)" "unprognostic (5.73e-2)" "unprognostic (1.14e-2)" "unprognostic (3.88e-1)" "unprognostic (3.73e-2)" "potential prognostic unfavorable (6.48e-4)" "unprognostic (5.24e-2)" "unprognostic (7.55e-2)" "unprognostic (3.84e-1)" "unprognostic (2.73e-1)" "unprognostic (1.89e-1)" "unprognostic (3.82e-1)" "unprognostic (5.56e-2)" "unprognostic (1.76e-1)" "unprognostic (6.82e-2)" "unprognostic (2.98e-1)" "unprognostic (6.62e-2)" "unprognostic (4.58e-2)" "unprognostic (2.09e-2)" "unprognostic (2.84e-2)" LETM1 "Mdm38, SLC55A1." ENSG00000168924 "Leucine zipper and EF-hand containing transmembrane protein 1" O95202 4 1811479-1856156 "Human disease related genes, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 114.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011029, HPA011100" Supported Supported Mitochondria NA NA 4700 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 38: Sub-cortical - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 5: Enterocytes - Absorption" 35 Mitochondria "HPA011029: AB_1852804, HPA011100: AB_1852802" "unprognostic (2.23e-1)" "unprognostic (3.44e-2)" "unprognostic (2.54e-1)" "unprognostic (5.40e-2)" "potential prognostic favorable (5.62e-4)" "unprognostic (1.73e-1)" "unprognostic (1.97e-1)" "unprognostic (8.98e-3)" "unprognostic (1.69e-1)" "unprognostic (2.05e-3)" "unprognostic (2.75e-2)" "unprognostic (1.71e-2)" "potential prognostic favorable (7.47e-5)" "potential prognostic unfavorable (3.78e-4)" "unprognostic (3.36e-3)" "unprognostic (7.72e-3)" "unprognostic (2.42e-2)" "unprognostic (3.02e-2)" "potential prognostic favorable (9.82e-4)" "unprognostic (1.93e-1)" "unprognostic (1.46e-3)" "unprognostic (1.81e-1)" "unprognostic (2.75e-2)" "unprognostic (3.20e-3)" "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (1.25e-2)" "unprognostic (5.39e-2)" "unprognostic (5.11e-2)" "unprognostic (1.41e-2)" LHFPL3 LHFPL4 ENSG00000187416 "LHFPL tetraspan subfamily member 3" Q86UP9 7 104328603-104908561 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 14.2;retina: 13.1" "Cell type enriched" "Detected in some" 19 "Oligodendrocyte precursor cells: 4494.9" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 4970.5" "Cancer enriched" "Detected in many" 15 "Glioblastoma Multiforme (TCGA): 52.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.0" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069691 Approved Vesicles No NA "Cluster 17: Neuronal - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 Vesicles "HPA069691: AB_2686171" "unprognostic (5.65e-2)" "unprognostic (1.60e-1)" "unprognostic (5.93e-2)" "unprognostic (9.88e-2)" "unprognostic (3.70e-2)" "unprognostic (7.26e-2)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (5.43e-2)" "unprognostic (5.35e-2)" "unprognostic (3.65e-1)" "unprognostic (6.80e-3)" LHX9 ENSG00000143355 "LIM homeobox 9" Q9NQ69 1 197911902-197935478 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "ovary: 18.3" "Cell type enhanced" "Detected in some" "Horizontal cells: 29.6;Leydig cells: 162.3;Ovarian stromal cells: 24.4;Peritubular cells: 49.0" "Cell type enhanced" "Detected in some" "ependymal cell: 10.6;splatter: 9.3;thalamic excitatory: 42.4" "Cancer enriched" "Detected in many" 10 "Kidney Chromophobe (TCGA): 36.2" "Region enhanced" "Detected in all" "midbrain: 36.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.5" "Adipose visceral - Mesothelial cells" "Group enriched" "Detected in many" 4 "hippocampal formation: 6.3;midbrain: 17.3;thalamus: 12.2" "Group enriched" "Detected in many" 5 "midbrain: 20.4;pons: 8.1;thalamus: 17.3" HPA009695 Uncertain Approved Nucleoplasm NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 6: Ovarian stromal cells - Transcription" 5 Nucleoplasm "HPA009695: AB_1079251" "unprognostic (5.32e-2)" "unprognostic (9.14e-2)" "unprognostic (1.05e-1)" "unprognostic (7.21e-2)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (9.10e-3)" "unprognostic (1.65e-1)" "unprognostic (3.01e-3)" LKAAEAR1 C20orf201 ENSG00000171695 "LKAAEAR motif containing 1" Q8TD35 20 64083376-64084398 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 31.4" "Group enriched" "Detected in some" 17 "Early spermatids: 463.4;Late spermatids: 690.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.2;Ovary Serous Cystadenocarcinoma (TCGA): 2.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 8.2;non-classical monocyte: 13.0" "Lineage enriched" "Detected in many" 13 "monocytes: 13.0" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056463 Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 11: Late spermatids - Unknown function" Nucleoplasm "HPA056463: AB_2683139" "unprognostic (4.12e-1)" "unprognostic (6.75e-2)" "unprognostic (6.81e-3)" "unprognostic (1.28e-2)" LRP8 "APOER2, HSZ75190, LRP-8, MCI1" ENSG00000157193 "LDL receptor related protein 8" Q14114 1 53242364-53328469 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.3;thyroid gland: 40.3" "Cell type enhanced" "Detected in many" "Astrocytes: 29.1;Bipolar cells: 40.2;Excitatory neurons: 34.7;Horizontal cells: 50.4;Inhibitory neurons: 111.8;Microglial cells: 41.2;Sertoli cells: 35.4" "Cell type enhanced" "Detected in all" "MGE interneuron: 249.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073031 Enhanced "Secreted in other tissues" Receptor NA NA 43000000 "Cluster 20: Non-specific - DNA binding" "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 8: Neurons - Neuronal signaling" 17 "HPA073031: AB_2732217" "unprognostic (1.32e-1)" "unprognostic (9.36e-3)" "unprognostic (1.03e-2)" "unprognostic (3.92e-3)" "unprognostic (1.07e-1)" "unprognostic (2.26e-1)" "unprognostic (3.84e-1)" "unprognostic (2.23e-3)" "unprognostic (3.77e-2)" "unprognostic (1.95e-2)" "validated prognostic unfavorable (1.69e-9)" "validated prognostic unfavorable (2.64e-4)" "potential prognostic unfavorable (1.18e-6)" "unprognostic (8.73e-2)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (1.19e-1)" "unprognostic (6.39e-3)" "unprognostic (1.12e-3)" "unprognostic (5.50e-2)" "unprognostic (8.79e-2)" "unprognostic (9.35e-2)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (1.64e-2)" "unprognostic (4.47e-2)" "unprognostic (2.60e-1)" "unprognostic (4.81e-3)" "unprognostic (1.33e-1)" "unprognostic (7.93e-2)" "unprognostic (8.15e-2)" LRRN2 "FIGLER7, GAC1, LRANK1, LRRN5" ENSG00000170382 "Leucine rich repeat neuronal 2" O75325 1 204617170-204685738 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 20.8" "Cell type enhanced" "Detected in many" "Astrocytes: 21.1;Excitatory neurons: 55.9;Granulosa cells: 15.8;Horizontal cells: 20.8;Inhibitory neurons: 38.2;Oligodendrocyte precursor cells: 36.8" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Breast Invasive Carcinoma (TCGA): 15.7;Glioblastoma Multiforme (TCGA): 48.9;Kidney Chromophobe (TCGA): 36.7;Ovary Serous Cystadenocarcinoma (TCGA): 40.3;Uterine Corpus Endometrial Carcinoma (TCGA): 27.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.4;testis cancer: 9.0" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029124 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" 2 "Endoplasmic reticulum" "HPA029124: AB_10601545" "unprognostic (1.44e-1)" "unprognostic (1.56e-2)" "unprognostic (3.90e-1)" "unprognostic (1.30e-3)" "unprognostic (1.74e-1)" "unprognostic (2.83e-1)" "unprognostic (1.04e-1)" "unprognostic (8.40e-3)" "unprognostic (6.59e-2)" "potential prognostic unfavorable (8.59e-4)" "unprognostic (4.65e-2)" "unprognostic (6.07e-2)" "unprognostic (3.42e-2)" "unprognostic (1.06e-3)" "unprognostic (7.67e-2)" "unprognostic (2.18e-1)" "unprognostic (6.05e-3)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (2.92e-2)" "unprognostic (7.32e-3)" "unprognostic (2.29e-1)" "unprognostic (1.31e-2)" "unprognostic (9.18e-2)" "unprognostic (1.37e-1)" "unprognostic (6.78e-3)" "unprognostic (9.35e-2)" "unprognostic (5.87e-2)" "unprognostic (3.33e-1)" LRRTM1 FLJ32082 ENSG00000162951 "Leucine rich repeat transmembrane neuronal 1" Q86UE6 2 80288351-80304752 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.4;salivary gland: 12.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.9;Horizontal cells: 5.0;Inhibitory neurons: 12.5;Oligodendrocyte precursor cells: 9.9;Schwann cells: 33.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Kidney Chromophobe (TCGA): 39.3;Ovary Serous Cystadenocarcinoma (TCGA): 49.4;Uterine Corpus Endometrial Carcinoma (TCGA): 34.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 8.0;Rhabdoid: 7.3" "Colon - Enteric glia cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046607, HPA062660" Approved Approved "Golgi apparatus" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Golgi apparatus" "HPA046607: , HPA062660: AB_2684824" "unprognostic (4.51e-1)" "unprognostic (1.58e-1)" "potential prognostic favorable (1.83e-5)" "unprognostic (2.16e-1)" "unprognostic (4.51e-2)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (2.13e-4)" "unprognostic (2.30e-1)" LRTM2 ENSG00000166159 "Leucine rich repeats and transmembrane domains 2" Q8N967 12 1820267-1836753 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "brain: 9.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.9;Excitatory neurons: 9.8;Horizontal cells: 21.4;Inhibitory neurons: 7.4" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Sarcoma: 4.3" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA055094, HPA062745" Uncertain Approved Cytosol NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Cytosol "HPA055094: AB_2682693, HPA062745: " "unprognostic (1.32e-1)" LSAMP "IGLON3, LAMP" ENSG00000185565 "Limbic system associated membrane protein" Q13449 3 115802363-117139389 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.8;retina: 39.4" "Group enriched" "Detected in many" 14 "Astrocytes: 3206.6;Excitatory neurons: 967.0;Inhibitory neurons: 2049.7;Oligodendrocyte precursor cells: 2327.6;Oligodendrocytes: 869.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 38.2;Kidney Chromophobe (TCGA): 37.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.3" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054051, HPA076122" Enhanced Cytosol NA NA 84000000 "Cluster 17: Neuronal - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 47: Astrocytes - Unknown function" 12 Cytosol "HPA054051: AB_2682358, HPA076122: AB_2686779" "unprognostic (1.13e-3)" "unprognostic (1.51e-1)" "unprognostic (5.88e-2)" "unprognostic (1.44e-1)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (5.72e-2)" "unprognostic (1.31e-2)" "unprognostic (5.51e-3)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (8.18e-5)" "unprognostic (1.52e-1)" "potential prognostic favorable (7.97e-5)" "unprognostic (1.16e-1)" "unprognostic (6.50e-2)" "unprognostic (3.69e-1)" "unprognostic (5.63e-2)" "unprognostic (1.57e-1)" "unprognostic (2.72e-1)" "unprognostic (6.57e-2)" "unprognostic (2.23e-1)" "unprognostic (2.02e-1)" "unprognostic (4.28e-3)" "unprognostic (3.41e-3)" "unprognostic (9.21e-3)" "unprognostic (1.26e-1)" "unprognostic (4.50e-3)" "unprognostic (1.22e-2)" LY6L ENSG00000261667 "Lymphocyte antigen 6 family member L" H3BQJ8 8 143080630-143083486 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "epididymis: 6.0;kidney: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Kidney Chromophobe (TCGA): 1.8;Prostate Adenocarcinoma (TCGA): 2.1" "Region enhanced" "Detected in some" "thalamus: 5.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 27 "breast cancer: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 70: DU4475 - Unknown function" "unprognostic (1.71e-1)" "unprognostic (2.80e-1)" LY6S ENSG00000291309 "Lymphocyte antigen 6 family member S" 8 143041844-143045678 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" LYPD6B "CT116, LYPD7" ENSG00000150556 "LY6/PLAUR domain containing 6B" Q8NI32 2 149038107-149215262 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 92.5" "Cell type enhanced" "Detected in many" "Early spermatids: 233.7;Gastric mucus-secreting cells: 78.4;Inhibitory neurons: 75.0;Late spermatids: 137.2;Secretory cells: 59.0" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 216.9;midbrain-derived inhibitory: 342.1" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 65.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "basophil: 13.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.8" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049239 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 32: Basophils - Transcription" "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 21: Early spermatids - Spermatogenesis" "HPA049239: AB_2680688" "unprognostic (5.09e-2)" "unprognostic (1.32e-1)" "unprognostic (6.69e-3)" "unprognostic (9.02e-2)" "unprognostic (1.68e-1)" "unprognostic (4.02e-3)" "unprognostic (2.24e-1)" "unprognostic (7.62e-2)" "unprognostic (3.25e-1)" "unprognostic (4.24e-2)" "unprognostic (4.84e-2)" "unprognostic (5.62e-2)" "unprognostic (2.19e-1)" "unprognostic (2.14e-2)" "unprognostic (6.55e-3)" "unprognostic (5.88e-3)" "unprognostic (2.92e-2)" "unprognostic (3.11e-1)" "unprognostic (2.41e-2)" "unprognostic (2.45e-1)" "unprognostic (5.56e-2)" "unprognostic (1.77e-1)" "unprognostic (8.78e-3)" "unprognostic (2.84e-1)" "unprognostic (2.72e-1)" "unprognostic (1.30e-1)" MAP3K14 "FTDCR1B, HS, HSNIK, NIK" ENSG00000006062 "Mitogen-activated protein kinase kinase kinase 14" Q99558 17 45263119-45317029 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 31.1;Microglial cells: 25.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 141.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 88.8" "Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027269, HPA027270" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 14: Langerhans cells - Innate immune response" 72 "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "HPA027269: AB_2732436, HPA027270: AB_2732437" "unprognostic (5.65e-2)" "unprognostic (3.28e-1)" "unprognostic (2.07e-2)" "unprognostic (2.53e-2)" "unprognostic (2.13e-1)" "unprognostic (1.43e-1)" "unprognostic (1.25e-1)" "unprognostic (3.03e-3)" "unprognostic (5.57e-3)" "unprognostic (1.20e-1)" "potential prognostic favorable (1.05e-4)" "unprognostic (6.54e-2)" "unprognostic (1.32e-2)" "unprognostic (6.69e-2)" "unprognostic (2.80e-2)" "unprognostic (1.18e-1)" "unprognostic (3.78e-1)" "unprognostic (2.24e-2)" "unprognostic (7.16e-2)" "unprognostic (2.28e-1)" "unprognostic (8.45e-3)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (2.46e-4)" "unprognostic (1.26e-1)" "unprognostic (2.76e-2)" "unprognostic (1.78e-3)" "unprognostic (1.42e-1)" "unprognostic (6.92e-2)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (4.23e-2)" MARK4 "FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D" ENSG00000007047 "Microtubule affinity regulating kinase 4" Q96L34 19 45079288-45305284 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 45.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039186 Approved Supported Cytosol NA NA "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 23 Cytosol "HPA039186: AB_10796223" "unprognostic (8.33e-2)" "unprognostic (6.98e-2)" "unprognostic (2.12e-1)" "unprognostic (1.62e-1)" "unprognostic (8.04e-2)" "unprognostic (5.55e-2)" "unprognostic (2.20e-1)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (2.44e-4)" "unprognostic (3.26e-1)" "unprognostic (1.57e-3)" "unprognostic (4.86e-2)" "unprognostic (2.25e-1)" "unprognostic (3.50e-2)" "unprognostic (2.57e-1)" "unprognostic (2.09e-2)" "unprognostic (5.73e-3)" "unprognostic (4.49e-1)" "unprognostic (1.86e-2)" "unprognostic (4.74e-2)" "unprognostic (4.74e-2)" "unprognostic (5.81e-2)" "unprognostic (2.24e-2)" "unprognostic (2.38e-2)" "unprognostic (2.78e-1)" "unprognostic (6.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.64e-1)" "unprognostic (1.34e-1)" "unprognostic (2.58e-2)" "unprognostic (6.88e-3)" MATN3 "EDM5, HOA" ENSG00000132031 "Matrilin 3" O15232 2 19992052-20012668 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 12.8;placenta: 10.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 21.8;Breast glandular cells: 4.7;Microglial cells: 4.5;Peritubular cells: 4.8;Sertoli cells: 5.4;Smooth muscle cells: 8.0" "Group enriched" "Detected in some" 5 "endothelial cell: 57.3;thalamic excitatory: 23.8" "Cancer enhanced" "Detected in all" "Pancreatic Adenocarcinoma (TCGA): 24.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 29.3;testis cancer: 24.9" "Lung - Alveolar cells type 1, Spleen - Fibroblast_2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 2.3" "HPA051250, HPA074980" Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA 650000 "Cluster 34: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 48: Smooth muscle cells - Signal transduction" 5 "Endoplasmic reticulum, Golgi apparatus, Vesicles" "HPA051250: AB_2681406, HPA074980: " "unprognostic (1.79e-1)" "unprognostic (5.73e-2)" "unprognostic (1.98e-2)" "unprognostic (8.73e-3)" "unprognostic (7.30e-3)" "unprognostic (6.85e-3)" "unprognostic (2.03e-1)" "unprognostic (7.35e-3)" "unprognostic (3.58e-2)" "unprognostic (1.45e-1)" "unprognostic (5.83e-3)" "unprognostic (1.34e-3)" "unprognostic (3.84e-1)" "potential prognostic unfavorable (6.84e-5)" "unprognostic (4.88e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (2.61e-2)" "unprognostic (2.51e-2)" "unprognostic (1.27e-2)" "unprognostic (4.96e-2)" "unprognostic (4.33e-2)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (2.11e-5)" "unprognostic (2.59e-1)" "unprognostic (4.94e-2)" "unprognostic (2.03e-2)" MED19 LCMR1 ENSG00000156603 "Mediator complex subunit 19" A0JLT2 11 57703710-57712221 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 194.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039912, HPA040860" Uncertain Enhanced "Nuclear bodies" NA NA "Cluster 32: Basophils - Transcription" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Mixed function" 133 "Nuclear bodies" "HPA039912: AB_10795262, HPA040860: AB_10794153" "unprognostic (7.59e-2)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (5.80e-4)" "unprognostic (1.40e-1)" "unprognostic (2.73e-1)" "unprognostic (2.76e-2)" "unprognostic (5.23e-2)" "unprognostic (7.43e-2)" "unprognostic (2.62e-2)" "unprognostic (6.66e-3)" "unprognostic (4.67e-2)" "unprognostic (2.27e-1)" "unprognostic (1.31e-1)" "validated prognostic unfavorable (1.34e-8)" "validated prognostic unfavorable (5.91e-4)" "unprognostic (1.44e-2)" "unprognostic (3.71e-2)" "unprognostic (1.01e-1)" "unprognostic (7.73e-2)" "potential prognostic favorable (8.98e-4)" "unprognostic (1.92e-3)" "unprognostic (3.51e-2)" "unprognostic (5.27e-2)" "unprognostic (1.60e-1)" "unprognostic (9.61e-2)" "unprognostic (1.61e-2)" "unprognostic (7.01e-2)" "unprognostic (1.32e-1)" "unprognostic (4.22e-1)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" MEI1 "MGC40042, SPATA38" ENSG00000167077 "Meiotic double-stranded break formation protein 1" Q5TIA1 22 41699503-41799456 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.9;testis: 38.4" "Cell type enhanced" "Detected in many" "Early spermatids: 62.4;Late spermatids: 53.9;NK-cells: 25.8;Plasma cells: 119.9;Spermatocytes: 43.2;T-cells: 25.2" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 27.9;midbrain-derived inhibitory: 36.5" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 23.3" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Myeloma: 13.7" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 4 "olfactory bulb: 2.3" HPA049240 Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA049240: AB_2680689" "unprognostic (3.71e-2)" "unprognostic (1.19e-3)" "unprognostic (1.69e-1)" "potential prognostic favorable (1.45e-7)" "unprognostic (8.34e-2)" "unprognostic (4.38e-2)" "unprognostic (4.20e-3)" "potential prognostic favorable (8.55e-4)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (4.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.47e-1)" "unprognostic (2.46e-2)" "potential prognostic favorable (7.97e-4)" "unprognostic (2.87e-2)" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (9.86e-2)" "unprognostic (4.90e-2)" "unprognostic (4.29e-2)" "unprognostic (2.01e-1)" "unprognostic (1.93e-2)" "unprognostic (2.28e-1)" "unprognostic (4.94e-3)" "unprognostic (1.00e-1)" "unprognostic (1.91e-1)" "unprognostic (1.83e-1)" "unprognostic (6.61e-2)" METTL2B "FLJ11350, METL, METTL2" ENSG00000165055 "Methyltransferase 2B, methylcytidine" Q6P1Q9 7 128476729-128506602 "Predicted intracellular proteins, Predicted membrane proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (2.13e-2)" "unprognostic (8.37e-2)" "unprognostic (4.62e-2)" "unprognostic (1.28e-3)" "unprognostic (1.10e-1)" "unprognostic (1.54e-1)" "unprognostic (2.75e-1)" "unprognostic (5.72e-2)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (1.93e-2)" "unprognostic (2.63e-1)" "unprognostic (1.85e-3)" "unprognostic (1.56e-3)" "unprognostic (4.44e-3)" "unprognostic (1.11e-1)" "unprognostic (9.60e-3)" "unprognostic (2.28e-1)" "unprognostic (3.46e-3)" "unprognostic (1.85e-1)" "unprognostic (3.30e-1)" "unprognostic (9.02e-2)" "unprognostic (1.95e-3)" "unprognostic (5.83e-3)" "unprognostic (5.04e-2)" "unprognostic (8.98e-2)" "unprognostic (1.65e-3)" "unprognostic (6.68e-2)" "unprognostic (4.59e-2)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (2.74e-1)" MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770502-102780628 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "endometrium 1: 256.8" "Cell type enriched" "Detected in some" 17 "Basal respiratory cells: 3568.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 85.8;Head and Neck Squamous Cell Carcinoma (TCGA): 152.9;Lung Squamous Cell Carcinoma (TCGA): 122.0" "Region enhanced" "Detected in some" "thalamus: 3.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "head and neck cancer: 33.9;Rhabdoid: 128.8;Sarcoma: 41.0" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" 7 Cytosol "Plasma membrane" "CAB002159: AB_564103" "unprognostic (2.23e-1)" "unprognostic (2.37e-2)" "unprognostic (1.10e-1)" "unprognostic (2.15e-1)" "unprognostic (3.72e-2)" "unprognostic (1.67e-1)" "unprognostic (2.90e-2)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (2.67e-5)" "unprognostic (1.32e-2)" "unprognostic (8.67e-2)" "unprognostic (8.83e-2)" "unprognostic (9.12e-2)" "unprognostic (4.05e-1)" "unprognostic (5.74e-2)" "unprognostic (1.39e-2)" "unprognostic (1.55e-3)" "unprognostic (3.99e-1)" "unprognostic (6.23e-2)" "unprognostic (1.31e-2)" "unprognostic (2.52e-1)" "unprognostic (4.43e-2)" "unprognostic (3.50e-1)" MMS19 "CIAO4, hMMS19, MET18, MMS19L" ENSG00000155229 "MMS19 homolog, cytosolic iron-sulfur assembly component" Q96T76 10 97458324-97498794 "Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051936, HPA056299" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 61 Nucleoplasm "HPA051936: AB_2681668, HPA056299: AB_2683091" "unprognostic (7.01e-2)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (5.39e-2)" "unprognostic (2.66e-2)" "unprognostic (5.26e-2)" "unprognostic (1.54e-2)" "potential prognostic favorable (1.91e-4)" "unprognostic (1.01e-2)" "unprognostic (1.48e-1)" "unprognostic (1.37e-1)" "unprognostic (1.70e-1)" "unprognostic (9.35e-2)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (6.95e-3)" "unprognostic (9.31e-2)" "unprognostic (1.06e-1)" "unprognostic (1.88e-1)" "unprognostic (2.67e-3)" "unprognostic (3.55e-3)" "unprognostic (4.15e-2)" "unprognostic (6.30e-2)" "unprognostic (5.07e-3)" "unprognostic (4.08e-2)" "unprognostic (1.76e-1)" "unprognostic (2.62e-1)" "unprognostic (9.54e-2)" "unprognostic (8.70e-2)" "unprognostic (2.90e-1)" "unprognostic (2.04e-1)" "unprognostic (5.01e-2)" MRAP2 "bA51G5.2, C6orf117" ENSG00000135324 "Melanocortin 2 receptor accessory protein 2" Q96G30 6 84033772-84090881 "Disease related genes, Human disease related genes, Predicted membrane proteins" Obesity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 54.6;Gastric mucus-secreting cells: 15.3;Inhibitory neurons: 32.0;Oocytes: 23.5" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 137.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.4" "Adipose visceral - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Spleen - Fibroblast_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 69: Neurons - Neuronal signaling" 12 "unprognostic (1.22e-2)" "unprognostic (1.67e-3)" "unprognostic (3.04e-1)" "unprognostic (1.36e-1)" "unprognostic (2.02e-2)" "unprognostic (1.93e-1)" "unprognostic (3.41e-2)" "unprognostic (5.28e-2)" "unprognostic (4.69e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (9.21e-2)" "unprognostic (2.68e-1)" "unprognostic (1.09e-1)" "unprognostic (3.22e-3)" "unprognostic (4.58e-3)" "unprognostic (3.93e-3)" "unprognostic (8.93e-2)" "unprognostic (2.40e-2)" "unprognostic (3.00e-3)" "unprognostic (3.74e-1)" "unprognostic (2.06e-2)" "unprognostic (3.53e-3)" "unprognostic (1.99e-1)" "unprognostic (9.00e-2)" "unprognostic (7.15e-2)" "unprognostic (1.18e-1)" MRM1 FLJ22578 ENSG00000278619 "Mitochondrial rRNA methyltransferase 1" Q6IN84 17 36601583-36608964 "Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021598 Supported Supported Mitochondria NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 91 Mitochondria "HPA021598: AB_1854097" "unprognostic (1.67e-1)" "unprognostic (3.93e-2)" "unprognostic (1.23e-2)" "unprognostic (4.89e-2)" "unprognostic (3.85e-2)" "unprognostic (2.81e-1)" "unprognostic (7.53e-2)" "unprognostic (6.33e-2)" "unprognostic (2.12e-2)" "unprognostic (1.02e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (1.28e-1)" "unprognostic (1.49e-1)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (1.96e-1)" "unprognostic (3.38e-1)" "unprognostic (1.59e-2)" "unprognostic (2.95e-1)" "unprognostic (1.88e-1)" "unprognostic (4.41e-2)" "unprognostic (9.23e-2)" "unprognostic (1.83e-1)" "unprognostic (7.40e-2)" "unprognostic (2.74e-1)" MTOR "FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1" ENSG00000198793 "Mechanistic target of rapamycin kinase" P42345 1 11106535-11262556 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069425, CAB080053, CAB080065, CAB080070, CAB080081, CAB080095, CAB080096, CAB080097" Supported Supported "Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" 146 "Golgi apparatus, Cytosol" "CAB069425: , CAB080053: , CAB080065: , CAB080070: , CAB080081: , CAB080095: , CAB080096: , CAB080097: " "unprognostic (6.92e-2)" "unprognostic (1.55e-1)" "unprognostic (2.78e-1)" "unprognostic (1.51e-1)" "unprognostic (2.83e-2)" "unprognostic (1.84e-2)" "unprognostic (4.46e-2)" "unprognostic (9.82e-3)" "unprognostic (5.57e-2)" "unprognostic (1.35e-1)" "unprognostic (1.59e-2)" "unprognostic (4.09e-2)" "unprognostic (9.36e-3)" "unprognostic (4.39e-2)" "unprognostic (3.09e-2)" "unprognostic (2.17e-1)" "unprognostic (1.61e-1)" "unprognostic (1.23e-1)" "unprognostic (3.68e-2)" "unprognostic (2.52e-2)" "unprognostic (7.53e-2)" "unprognostic (2.86e-1)" "unprognostic (2.87e-1)" "unprognostic (3.65e-1)" "unprognostic (1.35e-1)" "unprognostic (1.16e-2)" "unprognostic (2.62e-1)" "unprognostic (3.05e-1)" "unprognostic (3.97e-1)" "unprognostic (8.73e-2)" "unprognostic (3.60e-1)" MYBPH ENSG00000133055 "Myosin binding protein H" Q13203 1 203167811-203175826 "Predicted intracellular proteins" "Cell adhesion" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "salivary gland: 15.7;skeletal muscle: 71.7;tongue: 18.8" "Cell type enriched" "Detected in single" 33 "Skeletal myocytes: 30.2" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.9" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 30.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.5" "Cancer enhanced" "Detected in some" "Leukemia: 18.3;Sarcoma: 14.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061383 Enhanced Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 2: Skeletal myocytes - Muscle contraction" 1 "Nucleoplasm, Nucleoli, Mitochondria" "HPA061383: AB_2684497" "unprognostic (5.38e-3)" "unprognostic (2.71e-2)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (4.49e-4)" "unprognostic (4.57e-2)" "unprognostic (7.62e-2)" "unprognostic (1.17e-3)" "unprognostic (2.15e-1)" "unprognostic (3.23e-1)" "unprognostic (2.08e-2)" "unprognostic (1.43e-1)" MYF6 "bHLHc4, MRF4" ENSG00000111046 "Myogenic factor 6" P23409 12 80707634-80709474 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 41 "skeletal muscle: 424.5;tongue: 199.5" "Cell type enriched" "Detected in some" 203 "Skeletal myocytes: 743.6" "Cell type enhanced" "Detected in single" "pericyte: 1.2" "Cancer enriched" "Detected in some" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 5.0" "Region enriched" "Detected in single" 4 "thalamus: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA065102 Supported "Nucleoplasm,Mitotic spindle,Cytosol" Yes NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 2: Skeletal myocytes - Muscle contraction" 4 Nucleoplasm "Mitotic spindle, Cytosol" "HPA065102: " "potential prognostic unfavorable (7.06e-5)" MYO18B BK125H2.1 ENSG00000133454 "Myosin XVIIIB" Q8IUG5 22 25742144-26031045 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 117.0;skeletal muscle: 253.5;tongue: 53.4" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 82.0;Early spermatids: 54.9;Late spermatids: 40.5;Skeletal myocytes: 61.5" "Cell type enhanced" "Detected in many" "thalamic excitatory: 15.2" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.8" "Group enriched" "Detected in some" 4 "midbrain: 1.8;thalamus: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 11.3;Sarcoma: 6.8" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA000953 Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 68: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Centrosome" "HPA000953: AB_1079440" "unprognostic (1.47e-1)" "unprognostic (5.87e-3)" "unprognostic (1.00e-1)" MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 247.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 260.8;Alveolar cells type 2: 149.4;Hepatocytes: 371.1" "Group enriched" "Detected in many" 5 "pericyte: 1572.8;vascular associated smooth muscle cell: 673.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA 3600 "Cluster 83: Liver - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 42 "Plasma membrane" "HPA013607: AB_1854251, HPA060144: AB_2684211" "unprognostic (9.53e-2)" "unprognostic (1.72e-2)" "unprognostic (2.32e-1)" "unprognostic (1.54e-3)" "unprognostic (1.06e-1)" "unprognostic (8.94e-2)" "unprognostic (4.13e-1)" "unprognostic (9.79e-2)" "potential prognostic unfavorable (4.45e-4)" "unprognostic (1.65e-1)" "unprognostic (1.16e-3)" "unprognostic (1.49e-3)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (4.48e-2)" "potential prognostic favorable (1.97e-7)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (9.87e-4)" "unprognostic (5.17e-3)" "unprognostic (1.04e-2)" "unprognostic (6.00e-2)" "unprognostic (6.61e-2)" "unprognostic (2.51e-1)" "unprognostic (2.01e-2)" "unprognostic (1.16e-1)" "unprognostic (1.30e-1)" "unprognostic (1.52e-1)" "unprognostic (3.19e-3)" "unprognostic (7.46e-2)" "unprognostic (2.68e-1)" "unprognostic (7.69e-2)" "unprognostic (3.17e-1)" NAT16 "C7orf52, FLJ39237" ENSG00000167011 "N-acetyltransferase 16 (putative)" Q8N8M0 7 101170496-101180293 "Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 4.6;pancreas: 2.2;pituitary gland: 3.5;retina: 6.7;thyroid gland: 1.7" "Cell type enriched" "Detected in some" 11 "Horizontal cells: 83.1" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 8.2" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.8;Skin Cuteneous Melanoma (TCGA): 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 4.2" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Pancreas - Beta cells" HPA021918 Uncertain Approved Nucleoplasm NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Nucleoplasm "HPA021918: AB_1848922" "unprognostic (6.42e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (1.45e-2)" "potential prognostic favorable (5.24e-5)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (2.66e-6)" NEXN "NELIN, nexilin" ENSG00000162614 "Nexilin F-actin binding protein" Q0ZGT2 1 77888513-77943895 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 390.5;skeletal muscle: 652.7;tongue: 527.5" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 3529.9" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 154.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Smooth muscle cells, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells" "Region enhanced" "Detected in all" "basal ganglia: 40.4" "Group enriched" "Detected in all" 5 "basal ganglia: 12.3;midbrain: 18.6;pons: 13.6;thalamus: 34.4" "HPA011185, HPA011904" Approved Supported "Plasma membrane,Actin filaments" NA NA 3200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 68: Cardiomyocytes - Muscle contraction" 9 "Plasma membrane, Actin filaments" "HPA011185: AB_1854409, HPA011904: " "unprognostic (3.22e-3)" "unprognostic (1.15e-1)" "unprognostic (8.55e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-2)" "unprognostic (4.95e-2)" "unprognostic (1.09e-1)" "unprognostic (7.03e-2)" "unprognostic (5.98e-3)" "unprognostic (2.04e-1)" "unprognostic (2.02e-2)" "unprognostic (1.65e-1)" "unprognostic (3.76e-2)" "unprognostic (6.85e-3)" "unprognostic (2.70e-2)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-2)" "unprognostic (1.68e-1)" "unprognostic (3.44e-2)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (9.60e-2)" "unprognostic (2.13e-1)" "unprognostic (1.32e-1)" "unprognostic (4.75e-2)" "unprognostic (7.05e-3)" "unprognostic (2.14e-2)" "unprognostic (2.03e-1)" "unprognostic (8.26e-3)" "unprognostic (3.13e-2)" NKD1 ENSG00000140807 "NKD inhibitor of WNT signaling pathway 1" Q969G9 16 50548396-50649249 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Melanocytes: 17.2;Microglial cells: 43.8;Oligodendrocyte precursor cells: 53.8;Oligodendrocytes: 25.5;Smooth muscle cells: 19.6" "Cell type enhanced" "Detected in many" "endothelial cell: 182.5;fibroblast: 337.9" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 28.1;colorectal cancer: 19.6;Gastric cancer: 21.0" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041352, HPA049413" Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 32: Smooth muscle cells - Muscle contraction" 11 "Nucleoli fibrillar center" "HPA041352: AB_2677428, HPA049413: AB_2680753" "unprognostic (1.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-3)" "unprognostic (3.32e-1)" "unprognostic (4.14e-3)" "unprognostic (5.91e-3)" "potential prognostic favorable (2.81e-5)" "unprognostic (3.99e-1)" "unprognostic (1.55e-1)" "potential prognostic favorable (7.75e-4)" "unprognostic (4.95e-2)" "unprognostic (9.13e-3)" "unprognostic (1.35e-1)" "unprognostic (2.92e-2)" "potential prognostic unfavorable (6.16e-4)" "unprognostic (8.24e-2)" "unprognostic (1.54e-1)" "unprognostic (3.34e-1)" "unprognostic (4.73e-1)" "unprognostic (1.01e-2)" "unprognostic (2.11e-3)" "unprognostic (3.23e-1)" "unprognostic (8.60e-2)" "unprognostic (5.68e-3)" NMU ENSG00000109255 "Neuromedin U" P48645 4 55595229-55636698 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 97.4;skin 1: 37.4;vagina: 29.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 89.8;Basal squamous epithelial cells: 48.3;Squamous epithelial cells: 238.8;Suprabasal keratinocytes: 240.2" "Group enriched" "Detected in some" 7 "MGE interneuron: 38.6;splatter: 9.7;thalamic excitatory: 30.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 15.4" "Group enriched" "Detected in some" 10 "MAIT T-cell: 3.6;memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 37 "T-cells: 3.6" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Group enriched" "Detected in some" 8 "hypothalamus: 1.1;pons and medulla: 4.5" "Low region specificity" "Detected in some" HPA025926 Uncertain "Secreted in other tissues" Neuropeptide NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 12: Squamous epithelial cells - Keratinization" 57 "HPA025926: AB_1854539" "unprognostic (9.03e-2)" "unprognostic (6.75e-3)" "unprognostic (1.50e-1)" "unprognostic (1.49e-1)" "unprognostic (7.93e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-2)" "unprognostic (9.24e-2)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (3.38e-6)" "unprognostic (6.22e-3)" "potential prognostic unfavorable (7.06e-4)" "unprognostic (7.62e-2)" "unprognostic (1.63e-3)" "unprognostic (3.93e-1)" "unprognostic (1.32e-1)" "unprognostic (9.66e-2)" "unprognostic (8.76e-2)" "unprognostic (1.16e-1)" "unprognostic (4.62e-3)" "unprognostic (2.13e-2)" "unprognostic (2.42e-1)" "unprognostic (5.67e-2)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (6.58e-2)" "unprognostic (2.24e-2)" "unprognostic (1.02e-3)" NOG "SYM1, SYNS1" ENSG00000183691 Noggin Q13253 17 56593699-56595611 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation" "Developmental protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;placenta: 10.3" "Cell type enriched" "Detected in some" 6 "Extravillous trophoblasts: 15.3" "Cell type enhanced" "Detected in many" "bergmann glia: 10.3;LAMP5-LHX6 and Chandelier: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 73.0;naive CD8 T-cell: 35.0" "Lineage enriched" "Detected in single" 78 "T-cells: 73.0" "Cancer enhanced" "Detected in many" "Rhabdoid: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061318 Approved "Secreted to blood" "Developmental protein" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 19: NK-cells - Adaptive immune response" 7 "HPA061318: AB_2684478" "unprognostic (5.11e-2)" "unprognostic (2.45e-1)" "unprognostic (4.60e-2)" "unprognostic (3.72e-3)" "unprognostic (6.37e-3)" "unprognostic (2.73e-1)" "unprognostic (3.06e-2)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (1.88e-2)" "unprognostic (6.97e-2)" "unprognostic (6.29e-3)" NPAS2 "bHLHe9, MOP4, PASD4" ENSG00000170485 "Neuronal PAS domain protein 2" Q99743 2 100820139-100996829 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 106.8;Early spermatids: 80.4;Excitatory neurons: 145.5;Inhibitory neurons: 55.8;Microglial cells: 66.2;Oligodendrocyte precursor cells: 54.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019674 Uncertain Supported Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" 18 Nucleoplasm "HPA019674: AB_10601275" "unprognostic (1.60e-2)" "unprognostic (1.50e-1)" "potential prognostic favorable (3.65e-4)" "unprognostic (8.57e-3)" "unprognostic (2.67e-1)" "unprognostic (1.30e-2)" "unprognostic (2.23e-2)" "unprognostic (3.40e-3)" "unprognostic (2.29e-1)" "unprognostic (6.39e-2)" "unprognostic (1.03e-3)" "unprognostic (9.94e-2)" "unprognostic (2.39e-1)" "potential prognostic unfavorable (3.43e-5)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (5.25e-2)" "unprognostic (7.22e-2)" "unprognostic (1.27e-1)" "unprognostic (1.49e-1)" "unprognostic (2.39e-2)" "unprognostic (1.06e-2)" "unprognostic (4.07e-2)" "unprognostic (2.31e-1)" "unprognostic (9.53e-2)" "unprognostic (6.79e-2)" "unprognostic (2.07e-1)" "unprognostic (2.28e-1)" "unprognostic (1.26e-1)" "unprognostic (1.93e-3)" "unprognostic (1.22e-3)" NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 43.8;placenta: 39.0" "Cell type enhanced" "Detected in many" "Astrocytes: 161.3;Cytotrophoblasts: 118.9;Hofbauer cells: 421.2;Kupffer cells: 125.0;Microglial cells: 119.9;Proximal tubular cells: 105.6;Syncytiotrophoblasts: 95.7" "Cell type enhanced" "Detected in all" "astrocyte: 523.2;central nervous system macrophage: 434.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 440.3" "Group enriched" "Detected in many" 35 "granulocytes: 440.3;monocytes: 134.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Pituitary gland - Macrophages, Skin - Sebaceous gland cells, Spleen - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 160000 "Cluster 7: Non-specific - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Macrophages - Innate immune response" 2 Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (7.39e-3)" "unprognostic (1.01e-2)" "unprognostic (7.41e-2)" "unprognostic (1.06e-2)" "unprognostic (4.23e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (2.92e-1)" "unprognostic (1.90e-1)" "unprognostic (1.54e-1)" "unprognostic (2.87e-1)" "unprognostic (1.17e-1)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (6.22e-4)" "unprognostic (8.46e-2)" "unprognostic (3.33e-2)" "unprognostic (1.89e-2)" "unprognostic (3.47e-2)" "unprognostic (1.33e-2)" "unprognostic (4.97e-2)" "unprognostic (2.24e-1)" "unprognostic (3.63e-1)" "unprognostic (1.13e-2)" "unprognostic (5.75e-2)" "unprognostic (1.43e-1)" "unprognostic (8.56e-2)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (2.19e-1)" "unprognostic (1.43e-1)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" NPRL3 "C16orf35, CGTHBA, HS-40, MARE, NPR3, RMD11" ENSG00000103148 "NPR3 like, GATOR1 complex subunit" Q12980 16 84271-138677 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011741 Uncertain Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 1: Erythroid cells - Oxygen transport" 41 Cytosol "HPA011741: AB_1845577" "unprognostic (4.50e-2)" "unprognostic (3.33e-3)" "unprognostic (1.72e-1)" "unprognostic (7.57e-2)" "unprognostic (1.76e-1)" "unprognostic (5.30e-2)" "unprognostic (1.78e-1)" "unprognostic (1.19e-1)" "unprognostic (3.69e-1)" "unprognostic (3.12e-1)" "potential prognostic favorable (2.70e-4)" "unprognostic (3.31e-1)" "unprognostic (1.74e-1)" "unprognostic (1.70e-3)" "unprognostic (6.76e-2)" "unprognostic (3.09e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-2)" "unprognostic (1.94e-1)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (1.20e-1)" "unprognostic (2.17e-2)" "unprognostic (6.82e-2)" "unprognostic (1.29e-1)" "unprognostic (2.99e-2)" "unprognostic (1.69e-1)" "unprognostic (2.50e-1)" "unprognostic (2.87e-1)" "unprognostic (1.20e-2)" "unprognostic (1.09e-1)" NTNG1 "KIAA0976, Lmnt1" ENSG00000162631 "Netrin G1" Q9Y2I2 1 107140007-107484923 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.5;retina: 10.0" "Group enriched" "Detected in many" 4 "Excitatory neurons: 118.2;Inhibitory neurons: 155.1;Oligodendrocyte precursor cells: 399.0" "Cell type enhanced" "Detected in all" "thalamic excitatory: 2777.8" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 5.0" "Region enhanced" "Detected in all" "thalamus: 164.8" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.1" "Lineage enriched" "Detected in single" 4 "B-cells: 1.1" "Cancer enhanced" "Detected in many" "Bone cancer: 10.1" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "hippocampal formation: 26.0;midbrain: 79.9;pons: 71.8;thalamus: 99.3" HPA065954 Supported "Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" 4 "Plasma membrane" "HPA065954: AB_2685585" "unprognostic (4.68e-2)" "unprognostic (2.19e-2)" "unprognostic (7.07e-3)" "unprognostic (3.22e-1)" "unprognostic (1.82e-1)" "unprognostic (7.66e-2)" "unprognostic (1.00e-2)" NTS ENSG00000133636 Neurotensin P30990 12 85874295-85882992 "Predicted secreted proteins" Vasoactive "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 161.0" "Cell type enriched" "Detected in some" 132 "Enteroendocrine cells: 17404.5" "Group enriched" "Detected in many" 5 "ependymal cell: 297.4;thalamic excitatory: 80.1" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 482.3" "Group enriched" "Detected in all" 4 "cerebral cortex: 20.0;hypothalamus: 44.0;medulla oblongata: 27.4;midbrain: 20.6;thalamus: 59.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 286.9;ovarian cancer: 348.2;testis cancer: 189.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 88.3" "HPA026664, HPA071012" Enhanced Supported Vesicles "Secreted to digestive system" Other NA NA 760000 "Cluster 25: Small intestine - Absorption" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" 2 Vesicles "HPA026664: AB_2671936, HPA071012: " "potential prognostic unfavorable (9.70e-4)" "unprognostic (1.22e-1)" "unprognostic (2.23e-2)" "unprognostic (2.20e-3)" "unprognostic (1.97e-1)" "unprognostic (1.96e-1)" "unprognostic (2.14e-1)" "unprognostic (4.52e-1)" "unprognostic (2.29e-3)" "potential prognostic favorable (9.84e-4)" "unprognostic (6.07e-2)" "unprognostic (9.06e-2)" "unprognostic (5.65e-3)" "unprognostic (1.98e-2)" "unprognostic (1.05e-2)" "unprognostic (1.04e-3)" "unprognostic (1.10e-1)" "unprognostic (5.43e-2)" "unprognostic (1.02e-2)" "unprognostic (2.26e-3)" "unprognostic (1.58e-2)" "unprognostic (2.83e-2)" "unprognostic (4.63e-2)" "unprognostic (2.75e-1)" "unprognostic (1.35e-2)" NUDT18 "FLJ22494, MTH3" ENSG00000275074 "Nudix hydrolase 18" Q6ZVK8 8 22106874-22109419 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 35.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028581, HPA030125" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 16 Nucleoplasm "Golgi apparatus" "HPA028581: AB_10601381, HPA030125: AB_2673324" "unprognostic (1.90e-1)" "unprognostic (4.07e-2)" "unprognostic (2.05e-2)" "unprognostic (2.01e-3)" "unprognostic (2.85e-3)" "unprognostic (3.33e-2)" "unprognostic (1.01e-3)" "unprognostic (5.42e-3)" "unprognostic (9.99e-3)" "potential prognostic favorable (5.58e-4)" "unprognostic (8.14e-2)" "potential prognostic favorable (8.44e-4)" "unprognostic (1.24e-1)" "unprognostic (2.53e-1)" "unprognostic (4.75e-2)" "unprognostic (9.72e-3)" "unprognostic (7.78e-3)" "unprognostic (6.63e-2)" "unprognostic (8.12e-2)" "unprognostic (1.81e-2)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (8.19e-2)" "unprognostic (8.41e-2)" "unprognostic (9.87e-3)" "unprognostic (4.62e-2)" "unprognostic (4.90e-2)" "potential prognostic favorable (8.61e-6)" OPA3 "FLJ22187, MGA3" ENSG00000125741 "Outer mitochondrial membrane lipid metabolism regulator OPA3" Q9H6K4 19 45527767-45602212 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044881 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 48: Smooth muscle cells - Signal transduction" 1 Cytosol Nucleoplasm "HPA044881: AB_10964052" "unprognostic (2.24e-2)" "unprognostic (5.05e-2)" "unprognostic (9.02e-2)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-1)" "unprognostic (2.47e-2)" "unprognostic (9.82e-3)" "unprognostic (7.14e-2)" "validated prognostic favorable (1.80e-6)" "validated prognostic favorable (2.07e-4)" "potential prognostic favorable (1.61e-5)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (4.12e-2)" "unprognostic (2.79e-2)" "unprognostic (6.08e-2)" "unprognostic (9.88e-2)" "unprognostic (1.10e-1)" "unprognostic (2.27e-2)" "unprognostic (9.27e-2)" "unprognostic (1.28e-2)" "unprognostic (8.41e-2)" "unprognostic (2.24e-1)" "unprognostic (1.42e-1)" "unprognostic (4.49e-2)" "unprognostic (1.07e-2)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (3.52e-2)" "unprognostic (2.93e-2)" OPRL1 "KOR-3, NOCIR, NOPr, OOR, ORL1, PNOCR" ENSG00000125510 "Opioid related nociceptin receptor 1" P41146 20 64080082-64100643 "G-protein coupled receptors, Predicted membrane proteins" Behavior "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.8;lymphoid tissue: 4.4;testis: 6.5" "Cell type enhanced" "Detected in some" "Early spermatids: 12.2;Excitatory neurons: 6.0;Late spermatids: 31.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 3.9;eosinophil: 5.8;intermediate monocyte: 5.5;myeloid DC: 4.7;neutrophil: 4.9;non-classical monocyte: 12.5" "Group enriched" "Detected in many" 11 "dendritic cells: 4.7;granulocytes: 5.8;monocytes: 12.5" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064863 Approved "Primary cilium,Primary cilium tip" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 36: Late spermatids - Unknown function" 5 "Primary cilium, Primary cilium tip" "HPA064863: " "unprognostic (2.42e-1)" "potential prognostic unfavorable (5.72e-4)" "unprognostic (6.59e-2)" "unprognostic (3.65e-1)" "unprognostic (2.78e-1)" "unprognostic (1.09e-1)" "unprognostic (9.54e-2)" "unprognostic (4.49e-2)" "unprognostic (5.52e-2)" OPRM1 "MOP, MOR1" ENSG00000112038 "Opioid receptor mu 1" P35372 6 154010496-154246867 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;testis: 2.8" "Cell type enhanced" "Detected in some" "Early spermatids: 36.1;Excitatory neurons: 39.8;Inhibitory neurons: 22.4;Late spermatids: 34.8;Microglial cells: 9.8" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 374.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 4.3" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014509, HPA067435" Enhanced Supported NA NA "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 39 "HPA014509: AB_1854801, HPA067435: " "unprognostic (5.81e-2)" "unprognostic (3.24e-3)" "unprognostic (1.35e-1)" OR1E1 "HGM071, OR13-66, OR17-2, OR17-32, OR1E5, OR1E6, OR1E9P" ENSG00000180016 "Olfactory receptor family 1 subfamily E member 1" P30953 17 3397104-3398410 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 10 "Oocytes: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 44: Oocytes - Unknown function" OR3A1 "OLFRA03, OR17-40, OR40" ENSG00000180090 "Olfactory receptor family 3 subfamily A member 1" P47881 17 3291017-3298360 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 6.2;Excitatory neurons: 6.7;Microglial cells: 17.9;Oligodendrocyte precursor cells: 2.4;Oligodendrocytes: 4.9;Spermatogonia: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" 1 OR3A2 "OLFRA04, OR17-228, OR228" ENSG00000221882 "Olfactory receptor family 3 subfamily A member 2" 17 3276177-3386317 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 2.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Late spermatids: 1.9;Oocytes: 2.2;Spermatocytes: 5.7;Spermatogonia: 2.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 55.8" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.1" "Low region specificity" "Detected in single" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (1.40e-1)" "unprognostic (3.87e-3)" ORAI3 "MGC13024, TMEM142C" ENSG00000175938 "ORAI calcium release-activated calcium modulator 3" Q9BRQ5 16 30949068-30956461 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 54.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015022 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 53: Non-specific - Glycosylation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 50: Connective tissue cells - ECM organization" 1 "Nucleoplasm, Cytosol" "HPA015022: AB_1854807" "unprognostic (1.55e-1)" "unprognostic (1.92e-1)" "unprognostic (3.96e-1)" "unprognostic (2.27e-1)" "unprognostic (1.83e-2)" "unprognostic (2.58e-2)" "unprognostic (1.44e-2)" "unprognostic (4.76e-1)" "unprognostic (1.93e-1)" "unprognostic (2.69e-1)" "unprognostic (1.14e-2)" "unprognostic (2.15e-2)" "unprognostic (1.32e-1)" "unprognostic (8.52e-2)" "unprognostic (3.20e-1)" "unprognostic (9.05e-2)" "unprognostic (1.69e-1)" "unprognostic (6.16e-2)" "unprognostic (1.99e-1)" "unprognostic (9.35e-2)" "unprognostic (6.90e-2)" "unprognostic (1.66e-1)" "unprognostic (4.09e-2)" "unprognostic (5.88e-2)" "unprognostic (6.15e-3)" "unprognostic (2.88e-1)" "unprognostic (3.11e-2)" "unprognostic (6.45e-3)" "unprognostic (2.13e-2)" "unprognostic (6.35e-2)" "unprognostic (1.69e-2)" OTUB2 "C14orf137, FLJ21916, MGC3102" ENSG00000089723 "OTU deubiquitinase, ubiquitin aldehyde binding 2" Q96DC9 14 94026340-94048930 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 3.7;skin 1: 7.1;testis: 14.0" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1548.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002329, HPA075090" Enhanced NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 21: Testis - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 11: Late spermatids - Unknown function" 31 "HPA002329: AB_1079537, HPA075090: AB_2686734" "unprognostic (1.36e-1)" "unprognostic (1.12e-1)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (8.68e-5)" "unprognostic (5.27e-2)" "unprognostic (5.44e-2)" "unprognostic (4.46e-3)" "unprognostic (3.95e-1)" "unprognostic (7.47e-2)" "unprognostic (3.18e-1)" "unprognostic (1.12e-1)" "unprognostic (2.76e-3)" "unprognostic (6.02e-2)" "unprognostic (2.46e-1)" "unprognostic (3.79e-2)" "unprognostic (4.67e-3)" "unprognostic (1.51e-2)" "unprognostic (2.47e-1)" "unprognostic (1.16e-1)" "unprognostic (2.31e-1)" "unprognostic (7.83e-2)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" "unprognostic (1.81e-1)" "unprognostic (7.83e-2)" OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985713-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 56.0" "Cell type enhanced" "Detected in some" "mammillary body: 3.8" "Cancer enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 21.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.9;Rhabdoid: 5.3" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Beta cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.25e-1)" "unprognostic (1.67e-1)" "unprognostic (2.81e-1)" "unprognostic (7.82e-2)" "unprognostic (3.13e-1)" "unprognostic (7.17e-2)" "unprognostic (1.85e-2)" "unprognostic (2.31e-1)" "unprognostic (5.01e-1)" "unprognostic (1.78e-1)" "unprognostic (4.88e-1)" "unprognostic (2.65e-2)" "unprognostic (2.45e-1)" "unprognostic (1.82e-2)" "unprognostic (1.17e-1)" PALM2AKAP2 PALM2-AKAP2 ENSG00000157654 "PALM2 and AKAP2 fusion" "Q8IXS6, Q9Y2D5" 9 109498325-110172512 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 360.2;Alveolar cells type 1: 418.0;Cardiomyocytes: 311.8;Endothelial cells: 243.2;granulocytes: 222.3;Lymphatic endothelial cells: 221.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.7;naive B-cell: 10.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058905, HPA074153, HPA076866" Uncertain Supported "Plasma membrane" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 7: Adipose tissue - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "Plasma membrane" "HPA058905: AB_2683851, HPA074153: AB_2686669, HPA076866: " "unprognostic (1.47e-1)" "unprognostic (8.54e-2)" "potential prognostic unfavorable (1.88e-5)" "unprognostic (2.22e-1)" "unprognostic (2.25e-2)" "unprognostic (1.63e-1)" "unprognostic (6.42e-2)" "unprognostic (4.18e-2)" "validated prognostic favorable (3.03e-5)" "validated prognostic favorable (5.78e-5)" "potential prognostic unfavorable (7.73e-4)" "unprognostic (1.53e-1)" "unprognostic (3.83e-2)" "unprognostic (3.28e-2)" "unprognostic (7.13e-2)" "unprognostic (3.84e-3)" "unprognostic (2.77e-3)" "unprognostic (2.94e-2)" "unprognostic (4.11e-1)" "unprognostic (1.10e-1)" "unprognostic (1.43e-1)" "unprognostic (6.99e-3)" "unprognostic (8.08e-2)" "unprognostic (2.61e-2)" "unprognostic (1.82e-1)" "unprognostic (9.39e-2)" "unprognostic (3.44e-1)" PANK2 "C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN" ENSG00000125779 "Pantothenate kinase 2" Q9BZ23 20 3888839-3929887 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Coenzyme A biosynthesis" "Kinase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008440 Approved Supported Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 4: Testis - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 53: Fibroblasts - ECM organization" 14 Cytosol "HPA008440: AB_1079559" "unprognostic (1.88e-1)" "unprognostic (8.86e-3)" "unprognostic (4.17e-3)" "unprognostic (5.67e-2)" "unprognostic (4.07e-1)" "unprognostic (2.52e-1)" "unprognostic (3.38e-1)" "unprognostic (2.13e-2)" "unprognostic (3.36e-1)" "unprognostic (1.19e-2)" "potential prognostic favorable (4.15e-5)" "unprognostic (3.25e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.71e-6)" "unprognostic (3.11e-3)" "unprognostic (1.23e-1)" "unprognostic (1.62e-1)" "unprognostic (2.86e-2)" "potential prognostic unfavorable (9.70e-4)" "unprognostic (7.90e-2)" "unprognostic (3.52e-1)" "unprognostic (1.85e-1)" "unprognostic (1.18e-2)" "unprognostic (2.06e-1)" "unprognostic (3.22e-1)" "unprognostic (1.58e-2)" "unprognostic (1.36e-2)" "unprognostic (6.56e-2)" "unprognostic (6.54e-2)" "unprognostic (5.51e-2)" "unprognostic (1.45e-1)" PBX4 ENSG00000105717 "PBX homeobox 4" Q9BYU1 19 19561707-19618693 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.0;thyroid gland: 2.2" "Cell type enhanced" "Detected in many" "NK-cells: 17.0;Spermatocytes: 27.7;T-cells: 47.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 7 "gdT-cell: 1.7;MAIT T-cell: 1.7;memory CD4 T-cell: 1.2;memory CD8 T-cell: 1.9;naive CD4 T-cell: 1.2;naive CD8 T-cell: 1.0;T-reg: 3.1" "Lineage enriched" "Detected in single" 12 "T-cells: 3.1" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 4.1" "Adipose visceral - T-cells, Adrenal gland - T-cells, Minor Salivary Gland - T-cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049859, HPA056469" Enhanced Approved Vesicles NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 16: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 69 Vesicles "HPA049859: AB_2680918, HPA056469: AB_2797256" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "unprognostic (8.64e-3)" "unprognostic (6.47e-3)" "unprognostic (1.39e-2)" "unprognostic (1.11e-1)" "unprognostic (6.88e-3)" PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 84.7;heart muscle: 119.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 137.5;Extravillous trophoblasts: 68.1;Fibroblasts: 179.2;Syncytiotrophoblasts: 255.6" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 63.2;midbrain-derived inhibitory: 156.5;pericyte: 64.2" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 20.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Fibroblasts, Kidney - Podocytes, Pituitary gland - Corticotropes, Prostate - Fibroblasts, Skin - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" Other NA NA 1300000 "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 4 "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.46e-2)" "unprognostic (6.20e-2)" "unprognostic (1.49e-3)" "unprognostic (1.29e-1)" "unprognostic (1.84e-2)" "unprognostic (4.21e-2)" "unprognostic (1.41e-3)" "unprognostic (1.64e-1)" "unprognostic (2.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.96e-2)" "unprognostic (1.99e-2)" "unprognostic (1.06e-2)" "unprognostic (4.65e-2)" "unprognostic (1.73e-2)" "unprognostic (2.03e-1)" "unprognostic (3.32e-1)" "unprognostic (1.55e-1)" "unprognostic (7.71e-2)" "unprognostic (1.65e-1)" "unprognostic (1.08e-2)" "unprognostic (2.18e-1)" "unprognostic (5.68e-2)" "potential prognostic unfavorable (4.00e-5)" "unprognostic (2.34e-1)" PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 41.9" "Cell type enhanced" "Detected in many" "Astrocytes: 93.2;Bipolar cells: 79.2;Cardiomyocytes: 209.8;Horizontal cells: 95.7;Inhibitory neurons: 75.1;Smooth muscle cells: 71.7" "Cell type enriched" "Detected in all" 4 "vascular associated smooth muscle cell: 2523.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 7.4" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.4" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 20000 "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 7 "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (6.53e-2)" "unprognostic (8.36e-2)" "unprognostic (7.11e-3)" "unprognostic (1.17e-1)" "unprognostic (1.28e-1)" "unprognostic (2.67e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-3)" "potential prognostic favorable (4.05e-4)" "unprognostic (6.80e-2)" "unprognostic (3.94e-2)" "unprognostic (1.42e-2)" "unprognostic (2.96e-1)" "unprognostic (3.96e-1)" "unprognostic (2.73e-1)" "unprognostic (1.31e-1)" "unprognostic (2.90e-2)" "unprognostic (3.03e-1)" "unprognostic (5.24e-2)" "unprognostic (1.48e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (1.64e-1)" "unprognostic (1.03e-1)" PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 116.8;Hepatocytes: 129.3;Inhibitory neurons: 135.5;Langerhans cells: 262.1;Microglial cells: 171.8;Oligodendrocyte precursor cells: 509.9" "Cell type enhanced" "Detected in all" "fibroblast: 1300.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.2;intermediate monocyte: 79.5;myeloid DC: 83.7" "Group enriched" "Detected in many" 52 "dendritic cells: 83.7;monocytes: 79.5" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Prostate - Fibroblasts, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 38: Sub-cortical - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" 11 "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (6.49e-2)" "unprognostic (1.95e-1)" "unprognostic (4.11e-2)" "unprognostic (5.58e-2)" "unprognostic (3.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.73e-1)" "unprognostic (6.41e-3)" "unprognostic (1.18e-1)" "unprognostic (2.52e-3)" "potential prognostic favorable (4.99e-5)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (8.69e-4)" "unprognostic (2.88e-3)" "unprognostic (2.30e-1)" "unprognostic (1.73e-2)" "unprognostic (4.60e-2)" "unprognostic (6.65e-2)" "unprognostic (2.10e-1)" "unprognostic (7.78e-2)" "unprognostic (1.26e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-1)" "unprognostic (4.96e-2)" "potential prognostic favorable (5.47e-4)" "unprognostic (3.11e-1)" "unprognostic (2.88e-1)" "unprognostic (1.65e-2)" "unprognostic (1.08e-1)" "unprognostic (3.80e-2)" "unprognostic (3.30e-2)" PITPNM1 "DRES9, NIR2, PITPNM, Rd9, RDGB, RDGB1, RDGBA1" ENSG00000110697 "Phosphatidylinositol transfer protein membrane associated 1" O00562 11 67491768-67506263 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 58.6;Cone photoreceptor cells: 79.9;Distal enterocytes: 52.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060227 Approved Supported Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 17: Neuronal - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 5: Enterocytes - Absorption" 9 Cytosol Vesicles "HPA060227: AB_2684226" "unprognostic (3.14e-1)" "unprognostic (4.64e-2)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (6.23e-2)" "unprognostic (1.45e-2)" "unprognostic (3.99e-2)" "unprognostic (4.04e-1)" "unprognostic (9.63e-2)" "unprognostic (2.04e-1)" "potential prognostic favorable (8.36e-4)" "unprognostic (8.65e-2)" "unprognostic (1.36e-1)" "unprognostic (7.10e-2)" "unprognostic (1.38e-2)" "unprognostic (2.45e-1)" "unprognostic (8.56e-2)" "unprognostic (7.59e-3)" "unprognostic (6.40e-2)" "unprognostic (1.82e-3)" "unprognostic (1.99e-2)" "unprognostic (1.36e-1)" "unprognostic (2.87e-3)" "unprognostic (2.06e-2)" "unprognostic (2.10e-2)" "unprognostic (1.61e-1)" "unprognostic (1.88e-1)" "unprognostic (3.99e-2)" "unprognostic (2.21e-1)" "unprognostic (2.97e-1)" "unprognostic (1.02e-1)" PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 56.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 103.4;Syncytiotrophoblasts: 45.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 76.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Lung - Macrophages, Spleen - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 55000000 "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 58: Macrophages - Innate immune response" 8 "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (1.89e-1)" "unprognostic (2.57e-2)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (1.31e-1)" "unprognostic (1.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.13e-1)" "unprognostic (4.00e-3)" "unprognostic (1.37e-2)" "unprognostic (5.31e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (4.40e-3)" "unprognostic (1.45e-3)" "potential prognostic favorable (8.63e-4)" "unprognostic (8.57e-2)" "unprognostic (3.67e-2)" "unprognostic (6.24e-3)" "unprognostic (1.55e-1)" "unprognostic (7.45e-2)" "unprognostic (5.24e-3)" "unprognostic (2.31e-1)" "unprognostic (3.65e-3)" "unprognostic (8.13e-2)" "unprognostic (8.93e-2)" "unprognostic (3.76e-2)" "unprognostic (6.95e-3)" "unprognostic (9.63e-2)" "unprognostic (5.15e-3)" "unprognostic (2.52e-2)" "unprognostic (2.32e-1)" PLEKHD1 UPF0639 ENSG00000175985 "Pleckstrin homology and coiled-coil domain containing D1" A6NEE1 14 69484692-69531551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.8;parathyroid gland: 5.8;retina: 8.5" "Group enriched" "Detected in some" 4 "Bipolar cells: 57.3;Horizontal cells: 70.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 113.1" "Cancer enriched" "Detected in some" 4 "Kidney Chromophobe (TCGA): 7.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 3.7" "Lineage enriched" "Detected in single" 15 "dendritic cells: 3.7" "Cancer enhanced" "Detected in some" "prostate cancer: 2.5" "Breast - Breast glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 30.0" "Low region specificity" "Detected in all" HPA051875 Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA051875: AB_2681648" "unprognostic (9.47e-2)" "unprognostic (2.85e-2)" "unprognostic (3.87e-2)" "unprognostic (3.96e-3)" "unprognostic (6.13e-2)" "unprognostic (7.63e-2)" "unprognostic (3.06e-2)" POLR1A "DKFZP586M0122, FLJ21915, RPA1, RPA190, RPO1-4" ENSG00000068654 "RNA polymerase I subunit A" O95602 2 86020216-86106155 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010145, HPA031513, HPA031514, HPA049700" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 30: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 77 "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010145: AB_675814, HPA031513: AB_2673916, HPA031514: , HPA049700: AB_2680856" "unprognostic (3.11e-1)" "unprognostic (6.29e-2)" "unprognostic (4.01e-3)" "unprognostic (2.65e-3)" "unprognostic (2.44e-2)" "unprognostic (4.59e-1)" "unprognostic (1.79e-1)" "unprognostic (3.23e-1)" "unprognostic (1.53e-1)" "unprognostic (1.53e-3)" "unprognostic (3.38e-3)" "unprognostic (1.78e-1)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (2.95e-3)" "unprognostic (2.65e-3)" "potential prognostic unfavorable (7.50e-6)" "unprognostic (2.39e-1)" "unprognostic (1.55e-3)" "unprognostic (4.66e-3)" "unprognostic (7.12e-2)" "unprognostic (1.79e-3)" "unprognostic (4.45e-1)" "unprognostic (6.92e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-2)" "unprognostic (3.25e-3)" "unprognostic (7.94e-2)" "unprognostic (2.42e-1)" "unprognostic (9.39e-3)" "unprognostic (7.23e-2)" POMGNT2 "AGO61, C3orf39, FLJ14566, GTDC2" ENSG00000144647 "Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)" Q8NAT1 3 43079229-43106085 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034870, HPA040989" Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 79: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 1: Erythroid cells - Oxygen transport" 36 "HPA034870: AB_10602701, HPA040989: AB_2677238" "unprognostic (3.94e-2)" "unprognostic (4.41e-2)" "unprognostic (1.05e-1)" "unprognostic (9.87e-2)" "unprognostic (1.27e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-2)" "unprognostic (2.83e-1)" "unprognostic (1.51e-2)" "potential prognostic favorable (1.93e-5)" "unprognostic (1.55e-1)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (8.67e-5)" "unprognostic (1.01e-1)" "unprognostic (1.10e-1)" "unprognostic (1.26e-1)" "unprognostic (5.67e-2)" "unprognostic (2.79e-1)" "unprognostic (1.31e-1)" "unprognostic (4.88e-2)" "unprognostic (3.54e-2)" "unprognostic (7.91e-2)" "unprognostic (1.66e-2)" "potential prognostic favorable (5.89e-4)" "unprognostic (5.25e-2)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (2.35e-1)" PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715332 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 73.1;testis: 62.0" "Cell type enhanced" "Detected in many" "dendritic cells: 64.0;Early spermatids: 93.4;Late spermatids: 268.9" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 18.4;ependymal cell: 27.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 74.5" "Lineage enriched" "Detected in many" 15 "dendritic cells: 74.5" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Spleen - T-cells, Testis - Late spermatids" "Region enriched" "Detected in many" 7 "olfactory bulb: 27.3" "Low region specificity" "Detected in all" HPA046045 Uncertain Approved Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 72: Testis & Skeletal muscle - Protein ubiquitination" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Late spermatids - Unknown function" 4 Vesicles "HPA046045: AB_2679516" "unprognostic (2.31e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (2.45e-2)" "unprognostic (3.46e-2)" "unprognostic (9.89e-2)" "unprognostic (7.47e-3)" "unprognostic (2.29e-3)" "unprognostic (1.55e-2)" "unprognostic (2.24e-2)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (2.57e-1)" "unprognostic (3.77e-2)" "unprognostic (6.26e-3)" "unprognostic (1.30e-1)" "unprognostic (1.58e-1)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (7.18e-2)" "unprognostic (9.49e-2)" "unprognostic (4.50e-1)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" "potential prognostic favorable (5.53e-4)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (1.40e-1)" PPP1R17 "C7orf16, GSBS" ENSG00000106341 "Protein phosphatase 1 regulatory subunit 17" O96001 7 31687215-31708455 "Human disease related genes, Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 4.5;brain: 17.6" "Group enriched" "Detected in some" 5 "Late spermatids: 116.1;monocytes: 139.2" "Group enriched" "Detected in many" 5 "bergmann glia: 9.9;thalamic excitatory: 26.1" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 1.0;Testicular Germ Cell Tumor (TCGA): 1.1" "Group enriched" "Detected in many" 4 "amygdala: 18.6;cerebellum: 40.5;hypothalamus: 18.3;midbrain: 21.3;thalamus: 34.9" "Immune cell enriched" "Detected in some" 4 "non-classical monocyte: 52.2" "Lineage enriched" "Detected in many" 21 "monocytes: 52.2" "Cancer enhanced" "Detected in some" "Bone cancer: 4.9;lung cancer: 9.5" "Adrenal gland - Adrenal medulla cells, Testis - Late spermatids" "Region enriched" "Detected in many" 32 "cerebellum: 430.8" "HPA047819, HPA073123" Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 65: Cerebellum - Nervous system development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 11: Late spermatids - Unknown function" "HPA047819: AB_2680166, HPA073123: AB_2732219" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.65e-1)" "unprognostic (1.98e-1)" PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52170936-52229518 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chromosome partition, Host-virus interaction" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Smooth muscle cells, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol NA NA 1500000 "Cluster 25: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 269 Cytosol "CAB018599: AB_628178" "unprognostic (1.06e-1)" "unprognostic (1.54e-1)" "unprognostic (5.80e-2)" "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (7.28e-2)" "unprognostic (2.46e-1)" "unprognostic (3.11e-1)" "unprognostic (1.25e-2)" "unprognostic (3.88e-1)" "unprognostic (1.67e-1)" "unprognostic (3.73e-1)" "potential prognostic favorable (3.98e-4)" "validated prognostic unfavorable (1.94e-5)" "validated prognostic unfavorable (1.86e-5)" "unprognostic (3.92e-3)" "unprognostic (1.04e-2)" "unprognostic (1.21e-1)" "unprognostic (4.62e-2)" "unprognostic (3.82e-1)" "unprognostic (2.05e-2)" "unprognostic (7.98e-3)" "unprognostic (1.15e-1)" "unprognostic (2.46e-1)" "unprognostic (1.63e-1)" "unprognostic (3.23e-1)" "unprognostic (2.53e-2)" "unprognostic (3.13e-1)" "unprognostic (2.61e-2)" "unprognostic (2.56e-2)" "unprognostic (3.22e-1)" PPP4R4 "CFAP14, KIAA1622, PP4R4" ENSG00000119698 "Protein phosphatase 4 regulatory subunit 4" Q6NUP7 14 94146128-94279734 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.0;testis: 7.7" "Group enriched" "Detected in many" 5 "Astrocytes: 42.1;Cone photoreceptor cells: 27.2;Early spermatids: 19.0;Excitatory neurons: 61.1;Inhibitory neurons: 60.4;Late spermatids: 15.6;Oligodendrocyte precursor cells: 16.5;Spermatocytes: 31.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 9.6" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041866, HPA050321" Approved Supported "Primary cilium,Basal body,Cytosol" NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" 7 Cytosol "Primary cilium, Basal body" "HPA041866: AB_10804120, HPA050321: AB_2681086" "unprognostic (4.67e-2)" "unprognostic (1.11e-1)" "unprognostic (2.68e-1)" "unprognostic (6.41e-3)" "unprognostic (2.52e-1)" "unprognostic (2.85e-3)" "unprognostic (9.18e-2)" "unprognostic (6.70e-2)" "unprognostic (2.12e-1)" "unprognostic (5.54e-2)" PRKAG2 "AAKG, AAKG2, CMH6, H91620p, WPWS" ENSG00000106617 "Protein kinase AMP-activated non-catalytic subunit gamma 2" Q9UGJ0 7 151556124-151877125 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Cardiomyopathy, Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 138.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 201.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 69.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004246, CAB018641" Uncertain Approved Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" 9 Nucleoplasm "CAB018641: AB_2170355, HPA004246: AB_1078151" "unprognostic (6.14e-2)" "unprognostic (2.92e-1)" "unprognostic (1.59e-2)" "unprognostic (2.46e-2)" "unprognostic (6.06e-3)" "unprognostic (2.50e-1)" "unprognostic (3.90e-1)" "unprognostic (2.55e-2)" "unprognostic (2.12e-3)" "unprognostic (1.49e-1)" "potential prognostic favorable (3.99e-5)" "unprognostic (4.92e-2)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (1.44e-1)" "unprognostic (7.69e-3)" "unprognostic (2.97e-1)" "unprognostic (2.17e-1)" "unprognostic (7.02e-2)" "unprognostic (1.17e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" "unprognostic (9.16e-2)" "unprognostic (8.92e-2)" "unprognostic (3.05e-1)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (2.14e-1)" "unprognostic (3.16e-2)" "unprognostic (4.70e-2)" "unprognostic (1.74e-2)" "unprognostic (1.33e-1)" PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 70.8;Microglial cells: 255.9;NK-cells: 217.4;T-cells: 121.7" "Group enriched" "Detected in all" 6 "endothelial cell: 1433.4;leukocyte: 1439.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.2;MAIT T-cell: 91.4;memory CD4 T-cell: 88.5;memory CD8 T-cell: 136.2;naive CD4 T-cell: 107.8;naive CD8 T-cell: 104.9;NK-cell: 113.1;T-reg: 80.4" "Group enriched" "Detected in all" 13 "NK-cells: 113.1;T-cells: 136.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid gland - Endothelial cells" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (6.50e-2)" "unprognostic (4.26e-2)" "unprognostic (7.46e-2)" "unprognostic (9.39e-2)" "unprognostic (1.13e-1)" "unprognostic (2.75e-1)" "unprognostic (1.26e-1)" "unprognostic (4.00e-1)" "unprognostic (3.38e-3)" "unprognostic (9.30e-2)" "potential prognostic favorable (1.11e-6)" "unprognostic (1.71e-3)" "unprognostic (1.56e-1)" "unprognostic (2.38e-2)" "unprognostic (3.82e-3)" "unprognostic (9.72e-3)" "unprognostic (6.76e-3)" "unprognostic (1.85e-1)" "unprognostic (6.24e-2)" "unprognostic (2.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.32e-1)" "unprognostic (6.13e-3)" "unprognostic (8.13e-2)" "unprognostic (1.23e-1)" "unprognostic (2.71e-2)" "unprognostic (2.06e-1)" "unprognostic (5.27e-3)" "unprognostic (6.96e-2)" "unprognostic (1.55e-1)" "unprognostic (1.04e-1)" PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 21.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 228.4;Basal squamous epithelial cells: 48.8;Breast glandular cells: 101.0;Breast myoepithelial cells: 39.0;Club cells: 47.1;Ionocytes: 56.3" "Group enriched" "Detected in many" 4 "cerebellar inhibitory: 20.1;CGE interneuron: 45.9;LAMP5-LHX6 and Chandelier: 49.8" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 267.6;Lung Squamous Cell Carcinoma (TCGA): 231.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 243.3" "Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" Hormone NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 5 "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (3.52e-2)" "unprognostic (2.40e-1)" "unprognostic (9.06e-2)" "unprognostic (1.69e-2)" "unprognostic (3.17e-1)" "unprognostic (2.38e-2)" "unprognostic (3.37e-1)" "unprognostic (2.18e-1)" "unprognostic (9.76e-2)" "potential prognostic unfavorable (3.52e-4)" "potential prognostic unfavorable (1.92e-4)" "unprognostic (3.73e-3)" "potential prognostic unfavorable (4.19e-6)" "unprognostic (2.37e-3)" "unprognostic (1.21e-1)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (4.70e-2)" "unprognostic (3.84e-1)" "unprognostic (1.79e-1)" "unprognostic (1.26e-1)" "unprognostic (4.80e-3)" "unprognostic (7.93e-3)" "unprognostic (1.62e-1)" "unprognostic (2.72e-1)" "unprognostic (6.09e-3)" "unprognostic (2.83e-2)" "unprognostic (1.54e-2)" "unprognostic (2.66e-1)" "unprognostic (4.23e-3)" "unprognostic (1.01e-1)" PTPA "PPP2R4, PR53" ENSG00000119383 "Protein phosphatase 2 phosphatase activator" Q15257 9 129110950-129148946 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Intellectual disability, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005695, CAB022068, CAB035999, CAB080052, CAB080054, CAB080098" Approved Enhanced Nucleoplasm,Cytosol NA NA 3200000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" 20 Nucleoplasm Cytosol "CAB022068: , CAB035999: , CAB080052: , CAB080054: , CAB080098: , HPA005695: AB_1855658" "unprognostic (2.51e-1)" "unprognostic (8.89e-2)" "unprognostic (1.81e-1)" "unprognostic (1.17e-2)" "unprognostic (2.70e-3)" "unprognostic (5.06e-2)" "unprognostic (3.44e-2)" "unprognostic (5.93e-2)" "unprognostic (2.12e-1)" "unprognostic (1.90e-2)" "unprognostic (5.46e-1)" "potential prognostic favorable (9.12e-5)" "unprognostic (6.79e-2)" "unprognostic (2.87e-2)" "unprognostic (3.19e-2)" "unprognostic (3.51e-2)" "unprognostic (6.70e-2)" "unprognostic (4.08e-2)" "unprognostic (6.39e-2)" "unprognostic (1.52e-1)" "unprognostic (1.85e-1)" "unprognostic (2.94e-1)" "unprognostic (9.95e-3)" "unprognostic (5.53e-2)" "unprognostic (1.19e-1)" "unprognostic (1.59e-1)" "unprognostic (1.33e-1)" "unprognostic (6.97e-2)" "unprognostic (1.04e-3)" PTPN3 PTPH1 ENSG00000070159 "Protein tyrosine phosphatase non-receptor type 3" P26045 9 109375466-109498313 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 61.3;tongue: 45.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 77.8" "Cell type enhanced" "Detected in all" "ependymal cell: 192.8;thalamic excitatory: 239.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038343, HPA046728" Approved NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 59 "HPA038343: AB_10671741, HPA046728: AB_2679776" "unprognostic (1.56e-1)" "unprognostic (1.40e-3)" "unprognostic (1.37e-1)" "unprognostic (9.68e-2)" "unprognostic (1.40e-1)" "unprognostic (5.34e-2)" "unprognostic (3.70e-2)" "unprognostic (2.69e-1)" "unprognostic (8.49e-2)" "validated prognostic favorable (3.42e-10)" "validated prognostic favorable (5.56e-4)" "unprognostic (1.19e-1)" "unprognostic (2.86e-1)" "unprognostic (2.16e-1)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" "unprognostic (5.93e-2)" "unprognostic (1.60e-1)" "unprognostic (1.07e-1)" "unprognostic (1.48e-1)" "unprognostic (1.10e-1)" "unprognostic (5.22e-2)" "unprognostic (1.57e-1)" "unprognostic (7.40e-3)" "unprognostic (7.36e-2)" "unprognostic (2.38e-1)" "unprognostic (4.63e-2)" "unprognostic (1.75e-1)" "unprognostic (2.10e-1)" "unprognostic (8.85e-2)" PTPRA "HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA" ENSG00000132670 "Protein tyrosine phosphatase receptor type A" P18433 20 2873420-3039076 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029412, CAB034366, HPA069480" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 53: Fibroblasts - ECM organization" 26 Vesicles Nucleoplasm "CAB034366: AB_2269058, HPA029412: AB_10602293, HPA069480: AB_2686141" "unprognostic (3.00e-2)" "unprognostic (1.95e-1)" "unprognostic (1.95e-1)" "unprognostic (3.11e-2)" "unprognostic (1.21e-1)" "unprognostic (2.67e-2)" "unprognostic (9.68e-2)" "unprognostic (3.02e-2)" "unprognostic (6.42e-2)" "unprognostic (4.75e-2)" "potential prognostic favorable (1.23e-5)" "unprognostic (5.65e-3)" "unprognostic (3.20e-2)" "unprognostic (1.35e-2)" "unprognostic (6.20e-2)" "unprognostic (1.20e-1)" "unprognostic (1.67e-1)" "unprognostic (1.49e-2)" "unprognostic (9.19e-3)" "unprognostic (1.37e-2)" "unprognostic (1.80e-1)" "unprognostic (3.36e-2)" "unprognostic (1.03e-1)" "unprognostic (1.55e-1)" "unprognostic (3.29e-1)" "unprognostic (1.27e-1)" "unprognostic (3.87e-1)" "unprognostic (8.98e-2)" "unprognostic (2.47e-1)" "unprognostic (3.10e-1)" "unprognostic (2.45e-1)" PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase receptor type M" P28827 18 7566782-8406861 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 132.3;Astrocytes: 178.4;Inhibitory neurons: 720.5;Microglial cells: 251.4;Oligodendrocyte precursor cells: 210.8" "Cell type enhanced" "Detected in all" "endothelial cell: 1825.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 4.7" "Group enriched" "Detected in many" 33 "dendritic cells: 1.8;T-cells: 4.7" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Approved "Plasma membrane" NA Yes 77000000 "Cluster 30: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" 3 "Plasma membrane" "CAB022442: , CAB022443: , HPA003891: AB_2667073" "unprognostic (2.99e-3)" "unprognostic (1.85e-1)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (8.76e-2)" "unprognostic (3.26e-2)" "unprognostic (1.83e-1)" "unprognostic (7.55e-3)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "validated prognostic favorable (1.92e-9)" "validated prognostic favorable (3.76e-5)" "unprognostic (7.14e-2)" "unprognostic (2.15e-1)" "potential prognostic favorable (6.55e-4)" "unprognostic (2.44e-1)" "unprognostic (1.17e-1)" "unprognostic (4.61e-2)" "unprognostic (1.58e-1)" "unprognostic (8.29e-2)" "unprognostic (9.36e-2)" "unprognostic (4.17e-2)" "unprognostic (1.86e-2)" "unprognostic (7.57e-2)" "unprognostic (1.30e-1)" "unprognostic (2.33e-2)" "unprognostic (2.48e-1)" "unprognostic (1.31e-3)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.06e-1)" PVALB D22S749 ENSG00000100362 Parvalbumin P20472 22 36800684-36819479 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 649.1;parathyroid gland: 2046.8;retina: 361.9" "Group enriched" "Detected in some" 5 "Distal tubular cells: 673.1;Horizontal cells: 747.2" "Group enriched" "Detected in many" 4 "cerebellar inhibitory: 402.3;thalamic excitatory: 121.6" "Cancer enriched" "Detected in many" 32 "Kidney Chromophobe (TCGA): 1671.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 4.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.6" "Group enriched" "Detected in some" 9 "breast cancer: 16.4;Myeloma: 56.0" "Region enriched" "Detected in all" 5 "cerebellum: 2120.2" "Low region specificity" "Detected in all" "CAB002515, HPA048536" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" No NA "Cluster 4: Neutrophils - Degranulation" "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Nucleoplasm "Nucleoli, Cell Junctions" "CAB002515: AB_563948, HPA048536: AB_2680433" "unprognostic (3.87e-2)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (2.52e-2)" "unprognostic (4.22e-1)" "unprognostic (3.47e-2)" "unprognostic (9.15e-2)" "unprognostic (1.99e-2)" "unprognostic (1.27e-2)" "unprognostic (5.23e-2)" "unprognostic (2.06e-1)" "unprognostic (5.92e-3)" "unprognostic (5.78e-2)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (2.25e-1)" "unprognostic (4.54e-3)" "unprognostic (1.41e-2)" "unprognostic (1.28e-2)" "unprognostic (1.57e-1)" PYCR3 "FLJ13852, PYCRL" ENSG00000104524 "Pyrroline-5-carboxylate reductase 3" Q53H96 8 143603210-143609773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 4.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053776, HPA063416, HPA069706" Uncertain Supported "Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 30 Cytosol "Cytokinetic bridge, Mitotic spindle" "HPA053776: , HPA063416: AB_2685010, HPA069706: AB_2686178" "unprognostic (1.10e-1)" "unprognostic (3.89e-2)" "unprognostic (3.49e-2)" "unprognostic (1.82e-1)" "unprognostic (4.09e-2)" "unprognostic (3.28e-2)" "unprognostic (3.65e-2)" "unprognostic (3.12e-1)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (2.86e-8)" "unprognostic (2.46e-2)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (1.48e-2)" "unprognostic (5.95e-2)" "unprognostic (1.31e-2)" "unprognostic (3.03e-1)" "unprognostic (1.98e-3)" "unprognostic (2.19e-1)" "unprognostic (8.55e-3)" "unprognostic (1.20e-3)" "unprognostic (6.94e-3)" "unprognostic (3.20e-1)" "unprognostic (1.70e-1)" "unprognostic (8.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.38e-1)" "unprognostic (7.12e-2)" "unprognostic (1.19e-1)" RAB35 H-ray ENSG00000111737 "RAB35, member RAS oncogene family" Q15286 12 120095099-120117502 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054146 Approved NA NA 3800000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 29: Monocytes - Innate immune response" 41 "HPA054146: AB_2682399" "unprognostic (5.13e-1)" "unprognostic (1.27e-2)" "unprognostic (6.24e-2)" "unprognostic (5.78e-2)" "unprognostic (3.41e-1)" "unprognostic (8.23e-3)" "unprognostic (3.57e-1)" "unprognostic (1.09e-1)" "unprognostic (3.38e-1)" "unprognostic (1.48e-1)" "unprognostic (2.00e-3)" "unprognostic (5.38e-2)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (6.70e-5)" "unprognostic (2.29e-3)" "unprognostic (9.51e-3)" "unprognostic (1.33e-2)" "unprognostic (5.40e-3)" "unprognostic (3.71e-1)" "unprognostic (7.08e-2)" "unprognostic (2.58e-2)" "unprognostic (1.85e-1)" "unprognostic (3.99e-3)" "unprognostic (2.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.96e-2)" "unprognostic (3.77e-2)" "unprognostic (1.55e-1)" "unprognostic (2.70e-1)" "unprognostic (3.85e-1)" "unprognostic (9.65e-2)" RAB4A "HRES-1/RAB4, RAB4" ENSG00000168118 "RAB4A, member RAS oncogene family" P20338 1 229271062-229305894 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 32.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 32.8" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 1600000 "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 75: Serous glandular cells - Salivary secretion" 124 "unprognostic (1.13e-1)" "unprognostic (2.17e-2)" "unprognostic (2.35e-1)" "unprognostic (9.42e-2)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (9.61e-3)" "unprognostic (1.79e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" "potential prognostic favorable (1.49e-5)" "unprognostic (4.05e-2)" "unprognostic (1.94e-2)" "unprognostic (2.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.38e-1)" "unprognostic (2.26e-1)" "unprognostic (1.28e-1)" "unprognostic (1.89e-2)" "unprognostic (1.17e-1)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "unprognostic (3.48e-1)" "unprognostic (2.03e-1)" "unprognostic (1.69e-2)" "unprognostic (3.23e-1)" "unprognostic (3.45e-2)" "unprognostic (1.04e-2)" "unprognostic (7.72e-2)" "unprognostic (1.28e-1)" RALGAPA2 "AS250, C20orf74, dJ1049G11.4, KIAA1272, RapGAPalpha2" ENSG00000188559 "Ral GTPase activating protein catalytic subunit alpha 2" Q2PPJ7 20 20389530-20712644 "Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 201.3;Microglial cells: 138.7" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 778.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Pituitary gland - Corticotropes, Spleen - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042707, HPA043622" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 37: Glandular & Luminal cells - Unknown function" 4 "Plasma membrane, Cytosol" "HPA042707: AB_2678124, HPA043622: AB_2678585" "unprognostic (2.79e-2)" "unprognostic (4.97e-2)" "unprognostic (8.23e-2)" "unprognostic (2.00e-2)" "unprognostic (1.77e-2)" "unprognostic (2.72e-1)" "unprognostic (3.57e-1)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" "unprognostic (3.26e-3)" "unprognostic (1.17e-3)" "unprognostic (5.32e-2)" "unprognostic (4.58e-2)" "unprognostic (9.49e-2)" "unprognostic (1.48e-1)" "unprognostic (3.85e-2)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (1.99e-1)" "unprognostic (5.26e-3)" "unprognostic (3.51e-1)" "unprognostic (1.24e-1)" "unprognostic (2.21e-1)" "unprognostic (1.29e-1)" "unprognostic (2.22e-2)" "unprognostic (6.16e-2)" "unprognostic (3.20e-1)" "unprognostic (7.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.35e-1)" "unprognostic (3.31e-1)" RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 275.3" "Group enriched" "Detected in many" 5 "Excitatory neurons: 426.3;Inhibitory neurons: 399.2;Microglial cells: 136.0;Oligodendrocyte precursor cells: 284.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.0" "Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Hepatocytes, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular), Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Plasma membrane,Focal adhesion sites,Basal body,Cytosol,Mid piece" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 8: Neurons - Neuronal signaling" 9 "Focal adhesion sites" "Plasma membrane, Basal body, Cytosol, Mid piece" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (2.38e-1)" "unprognostic (5.65e-3)" "unprognostic (2.29e-1)" "unprognostic (8.91e-2)" "unprognostic (5.55e-2)" "potential prognostic favorable (3.87e-4)" "unprognostic (2.76e-2)" "unprognostic (1.22e-1)" "validated prognostic favorable (1.75e-9)" "validated prognostic favorable (7.16e-4)" "potential prognostic unfavorable (4.86e-6)" "unprognostic (3.61e-2)" "unprognostic (3.97e-3)" "unprognostic (8.16e-2)" "unprognostic (6.90e-2)" "unprognostic (2.44e-2)" "unprognostic (2.69e-2)" "unprognostic (4.47e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (2.53e-4)" "unprognostic (6.32e-2)" "unprognostic (8.34e-2)" "unprognostic (2.06e-1)" "unprognostic (1.84e-2)" "unprognostic (5.20e-2)" "unprognostic (1.28e-2)" "unprognostic (3.69e-2)" "unprognostic (5.85e-2)" "unprognostic (8.76e-2)" RASSF3 ENSG00000153179 "Ras association domain family member 3" Q86WH2 12 64507001-64697564 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 103.0" "Cell type enhanced" "Detected in many" "Langerhans cells: 180.3;monocytes: 168.7" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 180.0;choroid plexus epithelial cell: 226.7;endothelial cell: 286.0;leukocyte: 300.1;thalamic excitatory: 87.3;vascular associated smooth muscle cell: 136.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 124.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 124.5" "Cancer enhanced" "Detected in all" "prostate cancer: 128.3" "Prostate - Smooth muscle cells, Testis - Spermatogonia, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022664, CAB034035, HPA038469" Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" 26 "Plasma membrane, Cytosol" "CAB022664: , CAB034035: AB_2176848, HPA038469: AB_10671743" "unprognostic (1.74e-1)" "unprognostic (1.33e-1)" "unprognostic (1.57e-1)" "unprognostic (7.55e-2)" "unprognostic (4.07e-2)" "unprognostic (2.50e-1)" "unprognostic (1.49e-1)" "unprognostic (5.99e-2)" "unprognostic (1.77e-2)" "unprognostic (8.31e-2)" "potential prognostic favorable (8.23e-5)" "unprognostic (2.53e-2)" "unprognostic (4.60e-2)" "unprognostic (2.46e-3)" "unprognostic (2.06e-1)" "unprognostic (2.21e-1)" "unprognostic (1.03e-1)" "unprognostic (3.91e-2)" "unprognostic (8.64e-2)" "unprognostic (1.09e-1)" "unprognostic (2.90e-2)" "unprognostic (1.75e-2)" "unprognostic (3.83e-2)" "unprognostic (6.34e-2)" "unprognostic (1.22e-1)" "unprognostic (1.83e-1)" "unprognostic (3.75e-1)" "unprognostic (1.99e-3)" "unprognostic (9.86e-2)" "unprognostic (1.16e-1)" "unprognostic (6.92e-2)" RBPMS2 ENSG00000166831 "RNA binding protein, mRNA processing factor 2" Q6ZRY4 15 64739891-64775589 "Predicted intracellular proteins" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 290.8;intestine: 142.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 187.1;Oocytes: 66.2;Sertoli cells: 27.2;Smooth muscle cells: 50.0" "Group enriched" "Detected in some" 7 "choroid plexus epithelial cell: 20.3;pericyte: 54.4;vascular associated smooth muscle cell: 72.7" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 66.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 79.7" "Colon - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" 44 "unprognostic (2.06e-2)" "unprognostic (7.07e-2)" "unprognostic (1.90e-2)" "unprognostic (1.13e-1)" "unprognostic (1.48e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (5.00e-3)" "unprognostic (9.04e-2)" "unprognostic (9.04e-3)" "validated prognostic favorable (6.88e-6)" "validated prognostic favorable (8.96e-7)" "potential prognostic favorable (8.91e-5)" "unprognostic (7.84e-2)" "unprognostic (1.63e-2)" "unprognostic (8.07e-2)" "unprognostic (1.18e-2)" "unprognostic (2.25e-2)" "unprognostic (2.82e-2)" "unprognostic (3.81e-1)" "unprognostic (1.64e-1)" "unprognostic (3.84e-2)" "unprognostic (2.95e-3)" "unprognostic (4.92e-2)" "unprognostic (1.88e-2)" "unprognostic (1.58e-2)" "unprognostic (7.76e-2)" "unprognostic (9.83e-3)" "unprognostic (5.73e-2)" "unprognostic (7.54e-2)" "unprognostic (1.57e-1)" RDH12 "FLJ30273, LCA13, RP53, SDR7C2" ENSG00000139988 "Retinol dehydrogenase 12" Q96NR8 14 67701886-67734451 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Vision" Oxidoreductase "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "retina: 216.0;skin 1: 61.8" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 292.3;Rod photoreceptor cells: 445.1" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 11.6;thalamic excitatory: 8.3" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 10.3;Skin Cuteneous Melanoma (TCGA): 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 76: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" 8 "unprognostic (1.60e-1)" "unprognostic (3.38e-2)" "unprognostic (1.73e-2)" "unprognostic (2.71e-1)" "potential prognostic favorable (7.94e-6)" "unprognostic (8.23e-2)" "unprognostic (2.04e-2)" "unprognostic (1.23e-1)" "unprognostic (6.28e-2)" "unprognostic (3.65e-1)" "unprognostic (5.34e-2)" "unprognostic (1.75e-1)" "unprognostic (5.54e-1)" "unprognostic (8.63e-3)" "unprognostic (1.41e-1)" "unprognostic (4.39e-1)" RETREG3 "DKFZp686B1036, FAM134C, FLJ33806" ENSG00000141699 "Reticulophagy regulator family member 3" Q86VR2 17 42579513-42610623 "Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 89.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016492 Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 46: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" 149 "Nucleoplasm, Nuclear membrane" Cytosol "HPA016492: AB_1853027" "unprognostic (2.83e-1)" "unprognostic (2.86e-2)" "unprognostic (7.14e-2)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (7.85e-4)" "unprognostic (5.70e-2)" "unprognostic (2.25e-1)" "unprognostic (1.85e-1)" "unprognostic (3.34e-2)" "unprognostic (1.23e-3)" "unprognostic (4.73e-3)" "unprognostic (3.04e-1)" "unprognostic (3.15e-3)" "unprognostic (2.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.13e-1)" "unprognostic (3.53e-1)" "unprognostic (2.05e-2)" "unprognostic (6.77e-2)" "unprognostic (1.85e-2)" "unprognostic (3.21e-1)" "unprognostic (1.42e-1)" "unprognostic (4.49e-2)" "unprognostic (5.59e-3)" "unprognostic (1.09e-1)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (3.44e-2)" "unprognostic (2.40e-2)" RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 126.6;Excitatory neurons: 170.3;Inhibitory neurons: 136.1;Kupffer cells: 81.5;Macrophages: 80.3;Oligodendrocytes: 171.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts, Prostate - Fibroblasts, Spleen - Macrophages, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 58: Macrophages - Innate immune response" 4 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: AB_1856215" "unprognostic (2.26e-2)" "unprognostic (3.46e-1)" "unprognostic (8.83e-3)" "unprognostic (6.62e-2)" "unprognostic (6.72e-2)" "unprognostic (7.05e-2)" "unprognostic (4.65e-1)" "unprognostic (1.76e-1)" "unprognostic (4.52e-3)" "unprognostic (9.70e-2)" "potential prognostic favorable (3.26e-8)" "unprognostic (2.49e-3)" "potential prognostic favorable (8.64e-4)" "potential prognostic unfavorable (8.28e-5)" "unprognostic (1.27e-2)" "unprognostic (4.57e-3)" "unprognostic (2.79e-1)" "unprognostic (4.04e-2)" "unprognostic (3.63e-2)" "unprognostic (2.97e-2)" "unprognostic (2.46e-2)" "potential prognostic favorable (9.91e-4)" "unprognostic (5.28e-2)" "unprognostic (4.95e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (6.21e-4)" "unprognostic (2.27e-2)" "unprognostic (1.48e-2)" "unprognostic (5.99e-2)" "unprognostic (2.24e-2)" "unprognostic (1.38e-1)" RGP1 KIAA0258 ENSG00000107185 "RGP1 homolog, RAB6A GEF complex partner 1" Q92546 9 35749287-35758585 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020414, HPA021085" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 35: Non-specific - Mitochondria" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 55: Non-specific - Transcription" 5 Cytosol "Plasma membrane" "HPA020414: AB_1852289, HPA021085: AB_1852291" "unprognostic (6.11e-2)" "unprognostic (1.69e-1)" "unprognostic (1.72e-1)" "unprognostic (2.61e-3)" "unprognostic (1.91e-1)" "unprognostic (2.16e-1)" "unprognostic (1.38e-1)" "unprognostic (4.81e-2)" "unprognostic (3.98e-2)" "unprognostic (4.80e-2)" "validated prognostic favorable (2.53e-10)" "validated prognostic favorable (6.16e-4)" "potential prognostic favorable (6.35e-5)" "unprognostic (2.91e-3)" "unprognostic (6.35e-2)" "unprognostic (2.34e-1)" "unprognostic (3.06e-2)" "unprognostic (8.79e-2)" "unprognostic (1.66e-1)" "unprognostic (3.02e-2)" "unprognostic (2.58e-1)" "unprognostic (4.72e-3)" "unprognostic (4.52e-2)" "unprognostic (1.54e-1)" "unprognostic (1.00e-1)" "unprognostic (3.78e-2)" "unprognostic (1.85e-1)" "unprognostic (1.55e-1)" "unprognostic (3.03e-1)" "unprognostic (4.89e-3)" "unprognostic (1.10e-1)" RGS16 "A28-RGS14, RGS-r" ENSG00000143333 "Regulator of G protein signaling 16" O15492 1 182598623-182604389 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 100.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 238.8;Bipolar cells: 448.5;Extravillous trophoblasts: 230.8;Lymphatic endothelial cells: 402.1;Muller glia cells: 214.4;Smooth muscle cells: 479.3" "Cell type enriched" "Detected in many" 4 "thalamic excitatory: 165.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "hypothalamus: 94.6;midbrain: 144.7;thalamus: 275.6" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 73.1;Myeloma: 64.5" "Pituitary gland - Corticotropes" "Region enriched" "Detected in all" 5 "thalamus: 79.9" "Group enriched" "Detected in many" 7 "midbrain: 99.9;pons: 88.0;thalamus: 160.1" "HPA053250, HPA055824" Uncertain Approved Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 51: Thyroid gland - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Smooth muscle cells - Signal transduction" 4 Cytosol "HPA053250: AB_2682090, HPA055824: AB_2682934" "unprognostic (3.05e-1)" "unprognostic (2.84e-2)" "unprognostic (8.62e-2)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (5.58e-2)" "unprognostic (2.80e-2)" "unprognostic (1.43e-2)" "unprognostic (4.89e-2)" "unprognostic (1.66e-2)" "unprognostic (1.60e-1)" "unprognostic (1.58e-2)" "potential prognostic favorable (5.71e-4)" "unprognostic (3.11e-2)" "unprognostic (2.18e-2)" "potential prognostic favorable (5.15e-4)" "unprognostic (1.82e-1)" "unprognostic (3.03e-2)" "unprognostic (1.40e-2)" "unprognostic (1.99e-1)" "unprognostic (1.80e-2)" "unprognostic (8.46e-2)" "unprognostic (2.68e-2)" "unprognostic (7.79e-2)" "unprognostic (5.75e-2)" "unprognostic (2.62e-2)" "potential prognostic favorable (4.53e-4)" "unprognostic (2.50e-1)" "unprognostic (1.26e-1)" "unprognostic (1.66e-1)" "unprognostic (7.48e-3)" "unprognostic (2.92e-1)" RGS3 "C2PA, FLJ20370, PDZ-RGS3" ENSG00000138835 "Regulator of G protein signaling 3" P49796 9 113444731-113597743 "Plasma proteins, Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 146.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 83.9;Endothelial cells: 75.5;Melanocytes: 75.6;Proximal tubular cells: 169.3" "Cell type enhanced" "Detected in all" "endothelial cell: 136.1;ependymal cell: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "granulocytes: 19.0;NK-cells: 42.5;T-cells: 24.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Minor Salivary Gland - Endothelial cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" HPA044234 Supported "Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 38: Proximal tubular cells - Transmembrane transport" 4 "Plasma membrane" "HPA044234: " "unprognostic (1.39e-1)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (3.29e-1)" "unprognostic (1.50e-3)" "unprognostic (5.96e-2)" "unprognostic (4.42e-3)" "unprognostic (1.54e-2)" "unprognostic (4.75e-2)" "unprognostic (1.19e-2)" "unprognostic (1.59e-3)" "unprognostic (1.37e-1)" "unprognostic (1.34e-2)" "unprognostic (5.99e-2)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (1.88e-2)" "unprognostic (3.69e-2)" "unprognostic (1.57e-2)" "unprognostic (1.32e-3)" "unprognostic (1.79e-1)" "unprognostic (2.27e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (3.17e-1)" "unprognostic (3.20e-1)" "unprognostic (2.82e-2)" "unprognostic (1.10e-1)" "unprognostic (5.47e-2)" "unprognostic (3.41e-1)" "unprognostic (8.81e-2)" "unprognostic (1.30e-1)" "unprognostic (2.19e-1)" RGS7BP R7BP ENSG00000186479 "Regulator of G protein signaling 7 binding protein" Q6MZT1 5 64506015-64612319 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 118.3;Horizontal cells: 30.2;Inhibitory neurons: 163.2;Oligodendrocyte precursor cells: 63.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039600 Approved Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 65: Neurons - Synaptic function" 2 "Plasma membrane, Cytosol" "Actin filaments" "HPA039600: AB_2676591" "unprognostic (9.38e-2)" "unprognostic (2.01e-1)" "potential prognostic favorable (7.19e-4)" "potential prognostic favorable (3.17e-5)" "unprognostic (4.60e-3)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (1.15e-1)" "unprognostic (3.79e-3)" RGS8 "MGC119067, MGC119068, MGC119069" ENSG00000135824 "Regulator of G protein signaling 8" P57771 1 182641816-182684587 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 26.5;retina: 29.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 54.3;Early spermatids: 10.0;Horizontal cells: 42.8;Inhibitory neurons: 17.1;Late spermatids: 21.3" "Cell type enhanced" "Detected in many" "medium spiny neuron: 79.5;thalamic excitatory: 67.2" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.5;Testicular Germ Cell Tumor (TCGA): 2.2;Thyroid Carcinoma (TCGA): 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.4;ovarian cancer: 7.3" "Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in all" "cerebellum: 425.5" "Low region specificity" "Detected in all" HPA076764 Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 76: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 25: Bipolar cells - Visual perception" 1 "Vesicles, Plasma membrane" "HPA076764: AB_2732321" "unprognostic (3.54e-1)" "unprognostic (3.19e-2)" "unprognostic (1.72e-1)" "unprognostic (5.55e-2)" RIMS3 "NIM3, RIM3" ENSG00000117016 "Regulating synaptic membrane exocytosis 3" Q9UJD0 1 40620680-40665682 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "brain: 102.0" "Cell type enhanced" "Detected in many" "dendritic cells: 11.0;Excitatory neurons: 36.5;Inhibitory neurons: 20.2;Late spermatids: 34.2;Muller glia cells: 11.2" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 96.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Neuroblastoma: 47.3" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055285 Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 34: Neurons - Neuronal signaling" 5 "Nucleoli, Mitochondria" Nucleoplasm "HPA055285: AB_2682771" "unprognostic (2.14e-1)" "unprognostic (2.65e-1)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (8.97e-4)" "unprognostic (2.91e-3)" "potential prognostic favorable (4.89e-4)" "unprognostic (4.54e-1)" "unprognostic (1.16e-3)" "unprognostic (2.81e-2)" "unprognostic (8.92e-2)" "unprognostic (9.99e-3)" "unprognostic (1.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.23e-2)" "unprognostic (1.12e-1)" "unprognostic (1.49e-1)" "unprognostic (5.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.66e-2)" "unprognostic (3.81e-3)" "unprognostic (1.05e-1)" "unprognostic (3.00e-1)" "unprognostic (4.88e-2)" "unprognostic (1.35e-2)" RITA1 "C12orf52, FLJ14827, RITA" ENSG00000139405 "RBPJ interacting and tubulin associated 1" Q96K30 12 113185526-113192368 "Predicted intracellular proteins" "Neurogenesis, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 67.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039094, HPA039095, HPA061531" Supported Supported Nucleoplasm No No "Cluster 41: Basophils - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 22: Proximal enterocytes - Digestion" 6 Nucleoplasm "HPA039094: AB_10671037, HPA039095: AB_2676345, HPA061531: AB_2684554" "unprognostic (1.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.66e-1)" "unprognostic (1.42e-1)" "unprognostic (2.48e-2)" "unprognostic (4.58e-2)" "unprognostic (3.11e-2)" "unprognostic (3.26e-1)" "unprognostic (5.11e-2)" "potential prognostic favorable (7.67e-4)" "unprognostic (4.65e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (1.96e-1)" "unprognostic (1.46e-2)" "unprognostic (2.17e-1)" "unprognostic (5.56e-2)" "unprognostic (1.47e-1)" "unprognostic (2.24e-2)" "unprognostic (5.06e-3)" "unprognostic (6.76e-2)" "unprognostic (5.50e-2)" "unprognostic (1.98e-1)" "unprognostic (2.28e-1)" "unprognostic (4.28e-1)" "unprognostic (8.61e-3)" "unprognostic (3.43e-1)" "unprognostic (2.45e-1)" "unprognostic (4.42e-3)" RNF182 MGC33993 ENSG00000180537 "Ring finger protein 182" Q8N6D2 6 13924446-13980310 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.3;brain: 16.2;retina: 8.5" "Cell type enriched" "Detected in some" 4 "Astrocytes: 80.8" "Cell type enhanced" "Detected in many" "bergmann glia: 267.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 43.2" "Adipose visceral - Mesothelial cells, Breast - Endothelial cells, Spleen - Erythrocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012309 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 47: Astrocytes - Unknown function" 8 "Nucleoplasm, Golgi apparatus" Vesicles "HPA012309: AB_1856349" "unprognostic (1.46e-3)" "unprognostic (2.84e-2)" "unprognostic (9.91e-2)" "unprognostic (1.90e-1)" "unprognostic (7.46e-2)" "unprognostic (8.30e-3)" "unprognostic (2.54e-1)" "unprognostic (2.83e-1)" "unprognostic (1.60e-1)" "unprognostic (8.82e-3)" "unprognostic (3.82e-3)" "unprognostic (7.46e-3)" "unprognostic (1.59e-1)" "unprognostic (2.07e-1)" "unprognostic (1.31e-1)" "unprognostic (1.82e-2)" "unprognostic (2.59e-2)" "unprognostic (3.07e-2)" "unprognostic (6.00e-3)" RNF4 "RES4-26, SLX5, SNURF" ENSG00000063978 "Ring finger protein 4" P78317 4 2462220-2515857 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022047, HPA049356" Approved Supported "Nucleoplasm,Nuclear bodies,Microtubule ends" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 28: Dendritic cells - Antigen presentation" 164 "Nucleoplasm, Nuclear bodies" "Microtubule ends" "HPA022047: , HPA049356: AB_2680726" "unprognostic (1.36e-2)" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.36e-2)" "unprognostic (8.09e-3)" "unprognostic (6.68e-2)" "unprognostic (1.90e-1)" "unprognostic (1.89e-2)" "unprognostic (4.86e-2)" "unprognostic (1.23e-3)" "potential prognostic favorable (8.23e-5)" "unprognostic (3.79e-3)" "unprognostic (6.26e-2)" "unprognostic (2.94e-3)" "unprognostic (7.43e-3)" "unprognostic (2.09e-3)" "potential prognostic unfavorable (7.00e-4)" "unprognostic (7.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.32e-1)" "unprognostic (7.13e-3)" "unprognostic (2.43e-1)" "unprognostic (1.58e-1)" "unprognostic (6.50e-2)" "unprognostic (4.75e-2)" "unprognostic (3.57e-1)" "unprognostic (1.48e-1)" "unprognostic (2.30e-1)" "unprognostic (1.94e-1)" "unprognostic (2.05e-2)" "unprognostic (2.08e-1)" RNF6 DKFZp686P0776 ENSG00000127870 "Ring finger protein 6" Q9Y252 13 26132115-26222314 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 188.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039343, HPA040048" Approved Supported "Nuclear membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 40: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" 12 "Nuclear membrane" "HPA039343: AB_2676456, HPA040048: AB_10672969" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (5.18e-1)" "unprognostic (3.63e-3)" "unprognostic (1.29e-1)" "unprognostic (9.19e-2)" "unprognostic (1.20e-1)" "unprognostic (4.25e-3)" "unprognostic (1.49e-1)" "unprognostic (2.41e-2)" "potential prognostic favorable (5.48e-6)" "unprognostic (1.34e-2)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "unprognostic (1.73e-1)" "unprognostic (2.43e-1)" "unprognostic (2.04e-2)" "unprognostic (1.58e-1)" "unprognostic (4.58e-2)" "unprognostic (1.22e-2)" "unprognostic (1.60e-3)" "unprognostic (7.01e-2)" "unprognostic (2.35e-1)" "unprognostic (9.38e-2)" "unprognostic (4.38e-2)" "unprognostic (1.65e-1)" "unprognostic (1.15e-1)" "unprognostic (8.98e-3)" "unprognostic (4.53e-1)" "unprognostic (1.92e-2)" "unprognostic (1.52e-1)" ROBO1 "DUTT1, FLJ21882, SAX3" ENSG00000169855 "Roundabout guidance receptor 1" Q9Y6N7 3 78597239-79767998 "Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 299.1;Inhibitory neurons: 1449.4;Oligodendrocyte precursor cells: 326.9;Oligodendrocytes: 446.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Prostate - Urothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013524, HPA052968, HPA074461" Uncertain Supported "Plasma membrane,Primary cilium" NA NA 14000000 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 6 "Plasma membrane" "Primary cilium" "CAB013524: , HPA052968: AB_2682001, HPA074461: AB_2732256" "unprognostic (2.83e-1)" "unprognostic (4.14e-1)" "unprognostic (4.24e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-1)" "unprognostic (2.65e-2)" "unprognostic (4.46e-1)" "unprognostic (2.89e-1)" "potential prognostic favorable (1.50e-4)" "unprognostic (5.29e-2)" "potential prognostic favorable (5.71e-5)" "unprognostic (2.26e-1)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (5.19e-4)" "unprognostic (9.62e-2)" "unprognostic (3.60e-1)" "unprognostic (1.59e-1)" "unprognostic (9.87e-2)" "unprognostic (2.94e-1)" "unprognostic (1.36e-1)" "unprognostic (1.79e-1)" "unprognostic (8.14e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-2)" "potential prognostic favorable (7.36e-4)" "unprognostic (8.65e-2)" "unprognostic (1.48e-2)" "unprognostic (1.89e-1)" "unprognostic (1.95e-2)" "unprognostic (2.36e-1)" RORA "NR1F1, ROR1, ROR2, ROR3, RZRA" ENSG00000069667 "RAR related orphan receptor A" P35398 15 60488284-61229302 "Disease related genes, Human disease related genes, Metabolic proteins, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Receptor" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 80.2" "Cell type enhanced" "Detected in many" "Astrocytes: 2015.7;Excitatory neurons: 605.4;Inhibitory neurons: 1009.6;Microglial cells: 722.9;Oligodendrocyte precursor cells: 1430.1" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 11925.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in many" 4 "T-cells: 26.7" "Cancer enhanced" "Detected in many" "Myeloma: 25.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009861, HPA074448" Approved Supported Nucleoli NA NA "Cluster 1: T-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 13 Nucleoli "CAB009861: AB_2180141, HPA074448: " "unprognostic (7.67e-2)" "unprognostic (2.16e-2)" "unprognostic (9.23e-3)" "unprognostic (2.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (5.18e-2)" "unprognostic (3.89e-2)" "unprognostic (2.82e-1)" "unprognostic (1.12e-1)" "validated prognostic favorable (2.45e-9)" "validated prognostic favorable (1.69e-5)" "unprognostic (8.25e-3)" "unprognostic (7.33e-3)" "potential prognostic favorable (7.60e-4)" "unprognostic (1.67e-2)" "unprognostic (9.11e-3)" "unprognostic (1.73e-1)" "unprognostic (1.92e-1)" "unprognostic (2.24e-2)" "unprognostic (2.14e-1)" "unprognostic (5.26e-2)" "unprognostic (2.23e-2)" "unprognostic (2.38e-2)" "unprognostic (3.89e-1)" "unprognostic (1.08e-3)" "unprognostic (3.15e-2)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (4.13e-2)" "unprognostic (1.35e-1)" RPH3A "exophilin-1, KIAA0985, rabphilin" ENSG00000089169 "Rabphilin 3A" Q9Y2J0 12 112570380-112898881 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 116.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 18.1;Excitatory neurons: 69.1;Horizontal cells: 27.7;Inhibitory neurons: 95.9;monocytes: 24.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 16.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 6.3;intermediate monocyte: 3.0;neutrophil: 2.2;non-classical monocyte: 4.6" "Group enriched" "Detected in many" 5 "granulocytes: 2.2;monocytes: 6.3" "Group enriched" "Detected in many" 5 "Myeloma: 7.4;Neuroblastoma: 17.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002475 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" 6 "HPA002475: AB_1079837" "unprognostic (2.15e-1)" "unprognostic (6.45e-3)" "unprognostic (6.49e-2)" "unprognostic (1.63e-1)" "unprognostic (5.99e-2)" "unprognostic (1.01e-3)" "unprognostic (2.39e-3)" "unprognostic (1.73e-1)" RPS10-NUDT3 ENSG00000270800 "RPS10-NUDT3 readthrough" 6 34284887-34426071 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.3" "Cell type enhanced" "Detected in many" "B-cells: 32.1;Basal squamous epithelial cells: 97.1;Erythroid cells: 31.1;Gastric mucus-secreting cells: 27.7;Plasma cells: 36.7;Squamous epithelial cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 27.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 27.3" "Low cancer specificity" "Detected in all" "HPA047027, HPA047268, HPA048084, HPA055953" Uncertain Approved Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 49: Non-specific - Transcription" 1 Cytosol "HPA047027: AB_2679907, HPA047268: AB_2680007, HPA048084: AB_2680255, HPA055953: AB_2682984" "unprognostic (5.59e-2)" "unprognostic (2.53e-1)" "unprognostic (3.23e-1)" "unprognostic (2.90e-2)" "unprognostic (2.55e-2)" "unprognostic (2.52e-1)" "potential prognostic favorable (2.05e-4)" "potential prognostic unfavorable (4.26e-4)" "potential prognostic unfavorable (3.21e-4)" "unprognostic (1.24e-3)" "unprognostic (1.12e-1)" "unprognostic (4.66e-3)" "unprognostic (7.01e-3)" "potential prognostic unfavorable (8.86e-4)" "unprognostic (3.13e-3)" "unprognostic (5.06e-2)" "unprognostic (1.14e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-3)" "unprognostic (5.80e-3)" "unprognostic (2.34e-3)" "unprognostic (9.52e-3)" "unprognostic (1.50e-2)" "unprognostic (2.34e-2)" "unprognostic (1.61e-1)" "unprognostic (7.38e-2)" "unprognostic (1.15e-1)" RPS6KL1 "MGC11287, RSKL2" ENSG00000198208 "Ribosomal protein S6 kinase like 1" Q9Y6S9 14 74903951-74923302 "Enzymes, Predicted intracellular proteins" "Kinase, Ribonucleoprotein, Ribosomal protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 68.3;Cone photoreceptor cells: 59.5;Horizontal cells: 47.2;Rod photoreceptor cells: 78.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027451, HPA027794, HPA074903" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 17: Neuronal - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 2 Nucleoplasm Cytosol "HPA027451: AB_10599304, HPA027794: AB_10602098, HPA074903: " "unprognostic (3.03e-2)" "unprognostic (9.27e-3)" "unprognostic (3.66e-1)" "unprognostic (5.66e-2)" "unprognostic (7.68e-2)" "unprognostic (3.80e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.50e-1)" "unprognostic (1.40e-3)" "unprognostic (1.31e-1)" "unprognostic (7.19e-3)" "unprognostic (4.90e-2)" "unprognostic (1.09e-1)" "potential prognostic favorable (1.73e-4)" "unprognostic (6.18e-2)" "unprognostic (1.64e-1)" "unprognostic (9.85e-2)" "unprognostic (2.14e-1)" "unprognostic (1.12e-2)" "unprognostic (4.11e-2)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "unprognostic (2.24e-1)" "unprognostic (1.84e-1)" "unprognostic (1.18e-1)" "unprognostic (1.57e-1)" "unprognostic (4.35e-2)" "unprognostic (7.68e-2)" "unprognostic (1.72e-1)" RPUSD3 MGC29784 ENSG00000156990 "RNA pseudouridine synthase D3" Q6P087 3 9837849-9844602 "Predicted intracellular proteins" "mRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 87.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037551, HPA037552" Uncertain Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 31: Spermatocytes - Spermatogenesis" 10 Nucleoplasm "HPA037551: AB_2675538, HPA037552: AB_10672600" "unprognostic (5.07e-2)" "unprognostic (2.86e-2)" "unprognostic (6.71e-2)" "unprognostic (1.14e-1)" "unprognostic (2.76e-1)" "unprognostic (4.05e-2)" "unprognostic (3.00e-2)" "unprognostic (3.78e-3)" "unprognostic (3.32e-2)" "potential prognostic unfavorable (5.09e-6)" "unprognostic (2.86e-1)" "unprognostic (1.07e-1)" "unprognostic (1.89e-3)" "validated prognostic unfavorable (2.28e-5)" "validated prognostic unfavorable (7.15e-5)" "unprognostic (7.65e-3)" "unprognostic (3.06e-2)" "unprognostic (6.18e-2)" "unprognostic (1.91e-1)" "unprognostic (8.99e-2)" "unprognostic (7.45e-3)" "unprognostic (1.34e-1)" "unprognostic (9.22e-2)" "unprognostic (1.81e-1)" "unprognostic (3.04e-1)" "unprognostic (1.54e-1)" "unprognostic (3.92e-2)" "unprognostic (1.61e-1)" "unprognostic (1.44e-1)" "unprognostic (4.49e-2)" "unprognostic (2.75e-1)" RRP9 "RNU3IP2, U3-55K" ENSG00000114767 "Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein" O43818 3 51933429-51941904 "Predicted intracellular proteins" "rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038798 Uncertain Uncertain Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Mixed function" 40 Nucleoplasm "HPA038798: AB_10672653" "unprognostic (9.57e-2)" "unprognostic (9.97e-2)" "unprognostic (1.67e-1)" "unprognostic (9.04e-3)" "unprognostic (1.37e-1)" "unprognostic (2.17e-1)" "unprognostic (3.10e-2)" "unprognostic (2.56e-1)" "unprognostic (2.04e-1)" "unprognostic (5.28e-3)" "unprognostic (3.17e-2)" "unprognostic (2.62e-2)" "unprognostic (1.25e-2)" "validated prognostic unfavorable (2.17e-4)" "validated prognostic unfavorable (2.80e-7)" "unprognostic (3.84e-2)" "potential prognostic unfavorable (5.31e-4)" "unprognostic (8.62e-2)" "unprognostic (1.68e-1)" "unprognostic (3.20e-1)" "unprognostic (1.48e-1)" "unprognostic (6.11e-2)" "unprognostic (6.74e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (8.12e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.85e-1)" "unprognostic (6.42e-2)" "unprognostic (1.01e-1)" SCN2B ENSG00000149575 "Sodium voltage-gated channel beta subunit 2" O60939 11 118162806-118176639 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;heart muscle: 12.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.1;Cardiomyocytes: 15.0;Excitatory neurons: 21.2;Horizontal cells: 30.2;Inhibitory neurons: 30.6;Schwann cells: 10.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.5;Thyroid Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "unprognostic (3.26e-1)" "unprognostic (1.03e-1)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" "unprognostic (2.25e-1)" SEMA3E "coll-5, KIAA0331, M-SemaK, SEMAH" ENSG00000170381 "Semaphorin 3E" O15041 7 83363238-83649139 "Human disease related genes, Predicted secreted proteins" "Angiogenesis, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 49.8;Bipolar cells: 89.8;Excitatory neurons: 81.5;Mucus glandular cells: 70.2;Oligodendrocyte precursor cells: 234.9" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 510.1;deep-layer near-projecting: 506.8;oligodendrocyte precursor cell: 469.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.9" "Liver - Cholangiocyte, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029419, HPA063804" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" "Developmental protein" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 1 Vesicles Nucleoplasm "HPA029419: AB_10602090, HPA063804: AB_2685127" "unprognostic (1.32e-1)" "unprognostic (6.71e-2)" "unprognostic (5.60e-2)" "unprognostic (2.71e-1)" "unprognostic (5.09e-3)" "unprognostic (3.17e-2)" "unprognostic (1.34e-1)" "unprognostic (8.30e-2)" "unprognostic (1.22e-2)" "unprognostic (8.92e-2)" "unprognostic (1.47e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (7.41e-4)" "unprognostic (1.59e-1)" "unprognostic (6.16e-3)" "unprognostic (4.95e-2)" SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 97.9" "Cell type enhanced" "Detected in many" "Adipocytes: 38.2;Basal prostatic cells: 33.1;Bipolar cells: 23.9;Endothelial cells: 26.5;Suprabasal keratinocytes: 34.7" "Cell type enhanced" "Detected in many" "endothelial cell: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 84.1" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pituitary gland - Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" "Developmental protein" NA NA 1700000 7000000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA035008: AB_10604091" "unprognostic (7.06e-2)" "unprognostic (2.85e-1)" "unprognostic (1.13e-1)" "unprognostic (1.32e-1)" "unprognostic (1.99e-1)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (8.87e-4)" "unprognostic (1.99e-2)" "unprognostic (2.11e-1)" "unprognostic (2.39e-1)" "potential prognostic favorable (7.70e-7)" "unprognostic (3.53e-3)" "unprognostic (2.70e-1)" "potential prognostic unfavorable (5.63e-4)" "unprognostic (2.86e-2)" "unprognostic (3.23e-2)" "unprognostic (7.06e-3)" "unprognostic (2.15e-1)" "unprognostic (2.56e-1)" "unprognostic (8.54e-2)" "unprognostic (2.47e-1)" "unprognostic (6.67e-3)" "unprognostic (4.58e-2)" "unprognostic (8.47e-2)" "unprognostic (5.01e-2)" "unprognostic (3.43e-1)" "unprognostic (4.79e-2)" "unprognostic (1.85e-1)" "unprognostic (1.26e-1)" "unprognostic (1.91e-2)" "unprognostic (1.15e-1)" SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969504-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 59.0;Hepatocytes: 46.1;Intestinal goblet cells: 35.2;Paneth cells: 37.8;Proximal enterocytes: 45.4;Undifferentiated cells: 23.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" "Developmental protein" NA NA 1400000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" 4 "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (2.17e-1)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (4.29e-1)" "unprognostic (3.22e-2)" "unprognostic (3.00e-1)" "unprognostic (1.90e-1)" "unprognostic (3.15e-1)" "unprognostic (1.96e-3)" "unprognostic (8.64e-2)" "unprognostic (2.08e-1)" "potential prognostic favorable (2.91e-4)" "unprognostic (1.99e-2)" "unprognostic (2.49e-2)" "unprognostic (2.99e-1)" "unprognostic (2.11e-1)" "unprognostic (4.00e-3)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (6.05e-2)" "unprognostic (7.06e-2)" "unprognostic (2.80e-1)" "unprognostic (3.12e-3)" "unprognostic (2.49e-2)" "unprognostic (4.58e-1)" "unprognostic (7.00e-2)" "unprognostic (2.69e-2)" "unprognostic (1.53e-1)" "unprognostic (2.73e-2)" "unprognostic (1.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" SESN2 "DKFZp761M0212, HI95, SES2, SEST2" ENSG00000130766 "Sestrin 2" P58004 1 28259518-28282491 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 54.9;Syncytiotrophoblasts: 68.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018191 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 83: Liver - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 74: Neutrophils - Degranulation" 18 Cytosol "HPA018191: AB_1856750" "unprognostic (7.67e-2)" "unprognostic (8.19e-2)" "unprognostic (3.12e-1)" "unprognostic (1.30e-2)" "unprognostic (2.95e-2)" "unprognostic (1.34e-1)" "unprognostic (1.72e-1)" "unprognostic (3.42e-1)" "unprognostic (7.00e-2)" "unprognostic (3.44e-2)" "unprognostic (3.79e-2)" "unprognostic (7.73e-2)" "unprognostic (3.30e-1)" "potential prognostic unfavorable (7.48e-4)" "unprognostic (4.19e-2)" "unprognostic (1.34e-1)" "unprognostic (4.61e-2)" "unprognostic (6.76e-3)" "unprognostic (1.79e-1)" "unprognostic (7.53e-2)" "unprognostic (1.64e-1)" "unprognostic (4.66e-2)" "unprognostic (6.95e-2)" "unprognostic (9.01e-3)" "unprognostic (7.81e-2)" "unprognostic (1.67e-1)" "unprognostic (3.68e-3)" "unprognostic (1.89e-1)" "unprognostic (2.55e-1)" "unprognostic (1.42e-1)" "unprognostic (6.24e-3)" SHISAL1 KIAA1644 ENSG00000138944 "Shisa like 1" Q3SXP7 22 44243665-44312951 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.5;endometrium 1: 32.5;smooth muscle: 28.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.4;Endometrial stromal cells: 4.2;Excitatory neurons: 5.7;Inhibitory neurons: 11.7;Oocytes: 10.3" "Cell type enhanced" "Detected in many" "mammillary body: 71.5;thalamic excitatory: 60.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 17.4" "Pituitary gland - Lactotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051178 Uncertain Approved Vesicles,Cytosol No No "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 8: Neurons - Neuronal signaling" 43 "Vesicles, Cytosol" "HPA051178: AB_2681374" "unprognostic (1.93e-2)" "unprognostic (5.46e-3)" "unprognostic (5.73e-3)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (1.45e-3)" "unprognostic (1.16e-1)" "unprognostic (4.24e-2)" "unprognostic (8.02e-2)" "unprognostic (1.90e-1)" "unprognostic (1.39e-2)" "unprognostic (1.69e-1)" "unprognostic (4.92e-2)" "unprognostic (9.49e-2)" "unprognostic (3.42e-2)" "unprognostic (2.80e-2)" "unprognostic (1.45e-2)" "unprognostic (4.62e-2)" SHOX2 "OG12, OG12X, SHOT" ENSG00000168779 "Short stature homeobox 2" O60902 3 158095905-158106420 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 4.7;breast: 3.6;cervix: 3.0" "Group enriched" "Detected in some" 4 "Early spermatids: 56.2;Late spermatids: 45.0" "Cell type enriched" "Detected in some" 9 "thalamic excitatory: 59.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 6.9" "Region enhanced" "Detected in many" "thalamus: 44.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 5 "midbrain: 36.0;thalamus: 54.8" "Group enriched" "Detected in some" 6 "midbrain: 11.9;pons: 18.2;thalamus: 35.7" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 21: Early spermatids - Spermatogenesis" "unprognostic (8.10e-2)" "unprognostic (2.33e-1)" "unprognostic (1.88e-1)" "unprognostic (1.38e-2)" "unprognostic (8.41e-2)" "unprognostic (4.19e-3)" "unprognostic (4.37e-2)" "unprognostic (2.29e-2)" "unprognostic (3.60e-1)" "unprognostic (5.27e-1)" "unprognostic (5.64e-2)" "unprognostic (1.44e-1)" SLC2A13 HMIT ENSG00000151229 "Solute carrier family 2 member 13" Q96QE2 12 39755025-40106089 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.1;parathyroid gland: 21.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 489.9;Inhibitory neurons: 445.3;Oligodendrocyte precursor cells: 330.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006584, HPA061679" Enhanced Approved "Nuclear membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" 3 "Nuclear membrane" "HPA006584: AB_1849755, HPA061679: " "unprognostic (3.97e-2)" "unprognostic (1.97e-1)" "unprognostic (3.22e-1)" "unprognostic (7.44e-2)" "unprognostic (9.13e-2)" "unprognostic (5.29e-2)" "unprognostic (8.42e-2)" "unprognostic (1.25e-2)" "unprognostic (3.63e-1)" "unprognostic (2.64e-2)" "potential prognostic favorable (2.09e-7)" "unprognostic (9.14e-2)" "unprognostic (3.49e-2)" "unprognostic (3.80e-2)" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (6.39e-2)" "unprognostic (2.32e-1)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "unprognostic (2.00e-1)" "unprognostic (9.45e-2)" "unprognostic (6.85e-2)" "unprognostic (3.94e-2)" "unprognostic (2.59e-1)" "unprognostic (1.21e-2)" "unprognostic (1.32e-2)" SLC35C1 "FLJ11320, FUCT1" ENSG00000181830 "Solute carrier family 35 member C1" Q96A29 11 45804072-45813016 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 82.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 46.6;Proximal enterocytes: 57.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064001 Enhanced Supported "Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 83: Liver - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 4 "Golgi apparatus" "HPA064001: AB_2685171" "unprognostic (4.98e-2)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (2.41e-1)" "unprognostic (4.68e-3)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (3.29e-2)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (1.10e-1)" "unprognostic (1.59e-2)" "potential prognostic favorable (1.82e-4)" "unprognostic (1.61e-2)" "unprognostic (8.00e-3)" "unprognostic (2.89e-2)" "unprognostic (3.42e-2)" "unprognostic (1.51e-2)" "unprognostic (1.63e-3)" "unprognostic (7.17e-3)" "unprognostic (9.46e-3)" "unprognostic (1.82e-1)" "unprognostic (2.09e-1)" "unprognostic (1.73e-2)" "unprognostic (1.56e-1)" "unprognostic (1.41e-1)" "unprognostic (1.43e-1)" "unprognostic (3.16e-3)" "unprognostic (4.10e-1)" "unprognostic (2.41e-2)" "unprognostic (8.84e-2)" "unprognostic (3.52e-2)" "unprognostic (2.77e-2)" SLC35D3 FRCL1 ENSG00000182747 "Solute carrier family 35 member D3" Q5M8T2 6 136922301-136925660 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 5.9" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 1.8;Horizontal cells: 1.9;Ionocytes: 1.1;Pancreatic endocrine cells: 1.7" "Group enriched" "Detected in some" 4 "eccentric medium spiny neuron: 7.4;medium spiny neuron: 3.9;thalamic excitatory: 4.2" "Group enriched" "Detected in some" 4 "Colon Adenocarcinoma (TCGA): 3.9;Rectum Adenocarcinoma (TCGA): 4.7;Stomach Adenocarcinoma (TCGA): 1.4" "Group enriched" "Detected in many" 7 "basal ganglia: 7.9;hypothalamus: 12.5;midbrain: 4.7;thalamus: 12.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.8;Gastric cancer: 3.5;lung cancer: 3.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Group enriched" "Detected in many" 5 "basal ganglia: 29.6;olfactory bulb: 8.5" "Region enriched" "Detected in many" 6 "basal ganglia: 26.5" "HPA030431, HPA067497" Uncertain Approved "Centriolar satellite" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 57: Platelets - Hemostasis" 1 "Centriolar satellite" "HPA030431: AB_10601716, HPA067497: AB_2685854" "unprognostic (2.16e-1)" "unprognostic (1.75e-2)" "unprognostic (1.54e-2)" "unprognostic (2.06e-2)" "unprognostic (6.90e-2)" SLC35E1 FLJ14251 ENSG00000127526 "Solute carrier family 35 member E1" Q96K37 19 16549831-16572415 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 161.9" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016570, HPA062214" Approved Enhanced "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 28: Dendritic cells - Antigen presentation" 18 "Golgi apparatus" "HPA016570: AB_2190214, HPA062214: AB_2684713" "unprognostic (5.09e-3)" "unprognostic (3.99e-2)" "unprognostic (3.21e-3)" "unprognostic (1.57e-1)" "unprognostic (3.64e-1)" "unprognostic (3.88e-2)" "unprognostic (2.91e-1)" "unprognostic (2.09e-2)" "unprognostic (9.11e-2)" "unprognostic (2.63e-2)" "potential prognostic favorable (5.93e-4)" "unprognostic (1.24e-1)" "unprognostic (2.06e-1)" "unprognostic (1.58e-2)" "unprognostic (4.72e-3)" "unprognostic (1.58e-1)" "unprognostic (1.25e-2)" "unprognostic (7.59e-2)" "unprognostic (2.09e-2)" "unprognostic (1.65e-2)" "unprognostic (1.91e-3)" "unprognostic (8.97e-2)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (1.96e-1)" "unprognostic (1.46e-2)" "unprognostic (2.15e-1)" "unprognostic (2.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.80e-1)" "unprognostic (2.42e-2)" "unprognostic (1.04e-1)" SLC38A7 FLJ10815 ENSG00000103042 "Solute carrier family 38 member 7" Q9NVC3 16 58665109-58684770 "Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 31.9" "Cell type enriched" "Detected in all" 5 "Late spermatids: 802.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041777, HPA049428" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 36: Late spermatids - Unknown function" 44 "Plasma membrane, Cytosol" Nucleoplasm "HPA041777: AB_10796782, HPA049428: " "unprognostic (3.89e-2)" "potential prognostic unfavorable (2.80e-5)" "unprognostic (4.74e-2)" "unprognostic (1.26e-2)" "unprognostic (4.33e-2)" "unprognostic (5.37e-2)" "unprognostic (2.63e-1)" "unprognostic (1.76e-1)" "unprognostic (2.91e-3)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" "unprognostic (5.61e-2)" "unprognostic (2.27e-1)" "unprognostic (6.38e-3)" "unprognostic (1.24e-2)" "unprognostic (3.30e-2)" "unprognostic (2.47e-2)" "unprognostic (8.19e-3)" "unprognostic (5.11e-2)" "unprognostic (1.01e-1)" "unprognostic (7.48e-2)" "unprognostic (1.35e-1)" "unprognostic (2.57e-3)" "unprognostic (1.03e-1)" "unprognostic (2.50e-2)" "unprognostic (4.18e-2)" "unprognostic (8.92e-3)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (3.29e-2)" "unprognostic (1.17e-1)" SLC38A8 ENSG00000166558 "Solute carrier family 38 member 8" A6NNN8 16 84009667-84042795 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.7" "Cell type enriched" "Detected in some" 10 "Oocytes: 169.8" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 8 "Kidney Chromophobe (TCGA): 3.8;Skin Cuteneous Melanoma (TCGA): 9.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.0" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 44: Oocytes - Unknown function" "unprognostic (2.82e-1)" "unprognostic (4.00e-2)" SLC6A13 GAT2 ENSG00000010379 "Solute carrier family 6 member 13" Q9NSD5 12 220621-262873 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 147.4" "Cell type enriched" "Detected in some" 13 "Proximal tubular cells: 245.5" "Group enriched" "Detected in many" 31 "fibroblast: 408.5;pericyte: 665.0" "Group enriched" "Detected in many" 16 "Kidney Renal Clear Cell Carcinoma (TCGA): 135.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 88.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036449, HPA052726" Supported Nucleoplasm,Nucleoli,Mitochondria,Cytosol NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Mitochondria "Nucleoplasm, Nucleoli, Cytosol" "HPA036449: AB_2675130, HPA052726: AB_2681927" "unprognostic (3.49e-1)" "unprognostic (2.37e-1)" "unprognostic (1.29e-2)" "validated prognostic favorable (4.65e-8)" "validated prognostic favorable (3.80e-4)" "potential prognostic favorable (6.58e-5)" "unprognostic (3.89e-2)" "unprognostic (2.53e-3)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.85e-1)" "unprognostic (2.52e-2)" "unprognostic (3.24e-3)" SLC7A3 "ATRC3, CAT-3, FLJ14541" ENSG00000165349 "Solute carrier family 7 member 3" Q8WY07 X 70925579-70931125 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 19.3" "Cell type enriched" "Detected in some" 4 "Early spermatids: 10.0" "Cell type enhanced" "Detected in some" "LAMP5-LHX6 and Chandelier: 10.4" "Cancer enriched" "Detected in some" 9 "Testicular Germ Cell Tumor (TCGA): 60.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "testis cancer: 142.1" "Pituitary gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 71: Thymus - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" 3 "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-2)" "unprognostic (1.75e-1)" "unprognostic (1.77e-1)" "unprognostic (2.41e-2)" SLC8A1 NCX1 ENSG00000183023 "Solute carrier family 8 member A1" P32418 2 40097270-40611053 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 148.4" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 942.4;Excitatory neurons: 1224.1;Inhibitory neurons: 602.1;Microglial cells: 548.4;Oligodendrocyte precursor cells: 706.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 39.9" "Group enriched" "Detected in many" 6 "granulocytes: 39.9;monocytes: 12.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Kidney - Intercalated cells, Pituitary gland - Thyrotropes, Prostate - Smooth muscle cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022694, HPA070007" Uncertain Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" 3 "Nucleoplasm, Plasma membrane" "CAB022694: , HPA070007: AB_2686227" "unprognostic (2.25e-1)" "unprognostic (3.47e-1)" "unprognostic (1.84e-1)" "unprognostic (7.73e-2)" "unprognostic (1.04e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-1)" "unprognostic (1.89e-1)" "potential prognostic favorable (3.46e-8)" "unprognostic (1.15e-2)" "unprognostic (3.74e-1)" "unprognostic (1.25e-1)" "unprognostic (6.08e-2)" "unprognostic (2.97e-2)" "unprognostic (1.10e-2)" "unprognostic (5.82e-2)" "unprognostic (2.80e-2)" "unprognostic (1.49e-3)" "unprognostic (5.72e-2)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (3.00e-1)" "unprognostic (8.96e-3)" "unprognostic (1.65e-2)" "unprognostic (3.68e-1)" "unprognostic (8.56e-3)" SMCO2 "C12orf70, LOC341346" ENSG00000165935 "Single-pass membrane protein with coiled-coil domains 2" A6NFE2 12 27446736-27502185 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 17.4;Excitatory neurons: 9.1;Inhibitory neurons: 3.5;Late spermatids: 5.4;Pancreatic endocrine cells: 3.4" "Cell type enhanced" "Detected in many" "thalamic excitatory: 27.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA014366 Uncertain NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" "HPA014366: AB_1845544" "unprognostic (8.19e-3)" "unprognostic (6.44e-2)" "potential prognostic unfavorable (9.65e-5)" SMIM45 LINC00634 ENSG00000205704 "Small integral membrane protein 45" 22 41952150-41958939 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "brain: 12.2" "Cell type enhanced" "Detected in some" "Astrocytes: 5.0;Bipolar cells: 14.8;Early spermatids: 19.2;Excitatory neurons: 3.8;Horizontal cells: 4.4;Inhibitory neurons: 3.4;Late spermatids: 4.2;Oligodendrocyte precursor cells: 3.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" "unprognostic (1.04e-3)" "unprognostic (9.89e-2)" "unprognostic (5.35e-3)" "unprognostic (1.81e-1)" SMPX "Chisel, Csl, DFN6, DFNX4" ENSG00000091482 "Small muscle protein X-linked" Q9UHP9 X 21705978-21758116 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "heart muscle: 731.0;skeletal muscle: 1142.1;tongue: 1055.0" "Group enriched" "Detected in some" 57 "Cardiomyocytes: 1119.1;Skeletal myocytes: 489.9" "Group enriched" "Detected in some" 6 "cerebellar inhibitory: 6.5;mammillary body: 16.3;midbrain-derived inhibitory: 22.4;thalamic excitatory: 8.0" "Group enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 14.4;Stomach Adenocarcinoma (TCGA): 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Rhabdoid: 13.8;Sarcoma: 17.9" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 19.6" HPA077360 Approved "Plasma membrane" NA NA 28000 "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 68: Cardiomyocytes - Muscle contraction" "Plasma membrane" "HPA077360: AB_2732342" "unprognostic (1.42e-1)" "unprognostic (5.74e-2)" "potential prognostic unfavorable (2.64e-5)" "unprognostic (1.13e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (8.54e-4)" "unprognostic (5.84e-2)" "unprognostic (6.97e-2)" "unprognostic (1.04e-2)" "unprognostic (3.37e-1)" "unprognostic (1.30e-1)" "unprognostic (1.07e-2)" "unprognostic (6.08e-3)" "unprognostic (5.88e-1)" SP5 ENSG00000204335 "Sp5 transcription factor" Q6BEB4 2 170715337-170718078 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 8.5" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 7.3;Fibroblasts: 4.0;Intestinal goblet cells: 4.7;Prostatic glandular cells: 4.2;Sertoli cells: 5.4;Spermatogonia: 4.3" "Group enriched" "Detected in some" 4 "cerebellar inhibitory: 17.0;fibroblast: 11.6;midbrain-derived inhibitory: 10.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 12.1;colorectal cancer: 14.4;liver cancer: 12.4" "Liver - Hepatocytes" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Low region specificity" "Detected in some" HPA074123 Approved Nucleoplasm,Nucleoli NA NA "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 9: Endometrial stromal cells - Transcription" Nucleoli Nucleoplasm "HPA074123: AB_2686664" "unprognostic (2.69e-2)" "unprognostic (2.54e-2)" "unprognostic (1.20e-2)" "unprognostic (2.89e-2)" "unprognostic (1.04e-2)" "unprognostic (2.32e-1)" "unprognostic (8.27e-2)" "unprognostic (1.47e-3)" "unprognostic (3.19e-3)" "unprognostic (1.44e-1)" "unprognostic (6.31e-2)" "unprognostic (1.83e-1)" "unprognostic (2.18e-1)" "unprognostic (2.19e-2)" "unprognostic (2.60e-1)" "unprognostic (3.62e-2)" "unprognostic (3.40e-2)" "unprognostic (6.45e-2)" "unprognostic (5.65e-3)" "unprognostic (1.05e-2)" "unprognostic (1.06e-2)" "unprognostic (2.37e-1)" "unprognostic (1.23e-3)" SPATA20 "FLJ21347, SSP411, Tisp78" ENSG00000006282 "Spermatogenesis associated 20" Q8TB22 17 50543058-50555852 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 114.3" "Group enriched" "Detected in all" 16 "Early spermatids: 449.2;Late spermatids: 1537.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027144, HPA031442" Enhanced Approved "Principal piece" "Secreted in male reproductive system" "Developmental protein" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" 1 "Principal piece" "HPA027144: AB_1857418, HPA031442: AB_10610557" "unprognostic (5.49e-2)" "unprognostic (8.45e-2)" "unprognostic (1.81e-1)" "unprognostic (1.72e-1)" "unprognostic (2.97e-1)" "unprognostic (1.64e-2)" "unprognostic (8.37e-2)" "unprognostic (1.18e-2)" "unprognostic (1.78e-2)" "unprognostic (2.57e-1)" "unprognostic (3.29e-1)" "unprognostic (1.30e-1)" "unprognostic (2.47e-2)" "unprognostic (3.54e-2)" "unprognostic (4.91e-2)" "unprognostic (3.30e-1)" "unprognostic (2.43e-1)" "unprognostic (6.63e-2)" "unprognostic (1.24e-1)" "unprognostic (9.75e-2)" "unprognostic (8.94e-2)" "unprognostic (4.13e-2)" "unprognostic (8.49e-2)" "unprognostic (2.79e-1)" "unprognostic (4.91e-2)" "unprognostic (1.27e-1)" "unprognostic (2.02e-2)" "unprognostic (6.42e-2)" "unprognostic (2.37e-1)" "unprognostic (1.68e-1)" "unprognostic (1.72e-1)" SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 93.4;Lymphatic endothelial cells: 100.6;Muller glia cells: 148.2;Pancreatic endocrine cells: 113.8" "Cell type enhanced" "Detected in many" "lower rhombic lip: 9.2;vascular associated smooth muscle cell: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory bulb: 7.6" "HPA022829, HPA028761" Uncertain Supported "Vesicles,Plasma membrane,Primary cilium,Primary cilium transition zone" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 6 "Vesicles, Plasma membrane" "Primary cilium, Primary cilium transition zone" "HPA022829: AB_1857438, HPA028761: AB_10600814" "unprognostic (8.79e-2)" "unprognostic (3.30e-2)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (7.15e-3)" "unprognostic (4.47e-2)" "potential prognostic unfavorable (9.54e-4)" "unprognostic (2.81e-1)" "unprognostic (1.79e-1)" "unprognostic (1.35e-2)" "potential prognostic unfavorable (1.77e-5)" "unprognostic (3.26e-1)" "unprognostic (5.94e-2)" "unprognostic (9.57e-3)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (6.51e-5)" "unprognostic (6.52e-3)" "unprognostic (1.02e-1)" "unprognostic (1.79e-1)" "unprognostic (2.22e-2)" "unprognostic (2.28e-1)" "unprognostic (8.84e-3)" "unprognostic (3.05e-2)" "unprognostic (2.40e-2)" "unprognostic (5.75e-2)" "unprognostic (1.88e-2)" "unprognostic (3.06e-1)" "unprognostic (1.48e-1)" "unprognostic (2.03e-2)" "unprognostic (1.53e-1)" "unprognostic (2.39e-2)" SRM "SPS1, SRML1" ENSG00000116649 "Spermidine synthase" P19623 1 11054584-11060020 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis, Spermidine biosynthesis" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 444.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015746 Approved Approved Nucleoplasm,Cytosol NA NA 18000 "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 38: Sub-cortical - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 61: Plasma cells - Immunoglobulins & histones" 3 Nucleoplasm Cytosol "HPA015746: AB_1857472" "unprognostic (8.52e-3)" "unprognostic (5.00e-2)" "unprognostic (1.12e-2)" "unprognostic (4.37e-1)" "unprognostic (1.64e-1)" "unprognostic (3.07e-1)" "unprognostic (1.14e-1)" "unprognostic (7.69e-2)" "unprognostic (9.82e-2)" "unprognostic (3.27e-2)" "validated prognostic unfavorable (9.53e-7)" "validated prognostic unfavorable (1.27e-4)" "unprognostic (1.39e-3)" "validated prognostic unfavorable (1.36e-5)" "validated prognostic unfavorable (4.25e-7)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (1.01e-2)" "unprognostic (1.97e-1)" "unprognostic (2.14e-1)" "unprognostic (6.70e-2)" "potential prognostic favorable (8.40e-4)" "unprognostic (1.25e-1)" "unprognostic (2.79e-1)" "unprognostic (5.85e-2)" "unprognostic (3.63e-2)" "unprognostic (1.82e-2)" "unprognostic (3.38e-1)" "unprognostic (5.58e-2)" "unprognostic (6.95e-2)" "unprognostic (7.18e-3)" "unprognostic (8.47e-2)" ST3GAL3 "MRT12, SIAT6" ENSG00000126091 "ST3 beta-galactoside alpha-2,3-sialyltransferase 3" Q11203 1 43705824-43931165 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.9;tongue: 79.6" "Cell type enhanced" "Detected in many" "Astrocytes: 56.7;Excitatory neurons: 91.3;Inhibitory neurons: 115.2;Microglial cells: 54.6;Oligodendrocyte precursor cells: 62.7;Oligodendrocytes: 61.6;Rod photoreceptor cells: 74.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051102 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 8: Neurons - Neuronal signaling" 2 "HPA051102: AB_2681344" "unprognostic (3.12e-3)" "unprognostic (2.61e-1)" "unprognostic (5.16e-3)" "unprognostic (1.79e-1)" "unprognostic (2.52e-1)" "unprognostic (2.99e-1)" "unprognostic (1.39e-2)" "unprognostic (1.13e-2)" "unprognostic (6.67e-2)" "unprognostic (3.61e-3)" "unprognostic (1.77e-1)" "unprognostic (9.63e-2)" "unprognostic (2.20e-3)" "unprognostic (1.91e-2)" "unprognostic (6.56e-2)" "unprognostic (4.20e-2)" "unprognostic (3.85e-1)" "unprognostic (1.37e-1)" "potential prognostic favorable (4.74e-5)" "unprognostic (1.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.74e-3)" "unprognostic (2.85e-1)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (3.71e-3)" "unprognostic (2.12e-1)" "unprognostic (7.57e-2)" "unprognostic (6.44e-2)" "unprognostic (5.30e-2)" "unprognostic (1.56e-1)" STARD3 "es64, MLN64" ENSG00000131748 "StAR related lipid transfer domain containing 3" Q14849 17 39637090-39664201 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017021, HPA024307, HPA073948" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 30 "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "CAB017021: , HPA024307: , HPA073948: " "unprognostic (9.94e-2)" "unprognostic (3.94e-2)" "unprognostic (3.75e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (2.01e-2)" "unprognostic (4.27e-2)" "unprognostic (1.63e-2)" "unprognostic (1.03e-2)" "unprognostic (9.37e-3)" "potential prognostic favorable (2.63e-6)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (2.31e-3)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (6.49e-2)" "unprognostic (4.77e-2)" "unprognostic (9.56e-2)" "unprognostic (3.15e-1)" "unprognostic (3.50e-2)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (1.46e-1)" "unprognostic (6.97e-2)" "unprognostic (2.32e-3)" "unprognostic (1.56e-1)" "unprognostic (1.16e-1)" "unprognostic (6.93e-2)" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" STK32C "MGC23665, PKE, YANK3" ENSG00000165752 "Serine/threonine kinase 32C" Q86UX6 10 132207492-132331847 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.6;testis: 52.6" "Cell type enhanced" "Detected in many" "Early spermatids: 287.2;Late spermatids: 108.1;Spermatocytes: 72.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 55.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017894 Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 13: Spermatids - Transcription" 6 "HPA017894: AB_1857591" "unprognostic (3.58e-2)" "unprognostic (1.13e-1)" "unprognostic (5.78e-2)" "unprognostic (3.72e-2)" "unprognostic (1.59e-3)" "unprognostic (9.15e-2)" "unprognostic (2.08e-3)" "unprognostic (8.91e-3)" "unprognostic (1.24e-1)" "unprognostic (1.67e-2)" "unprognostic (1.83e-3)" "potential prognostic unfavorable (7.10e-7)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (2.66e-5)" "unprognostic (2.45e-2)" "unprognostic (6.36e-2)" "unprognostic (2.49e-1)" "unprognostic (1.85e-1)" "unprognostic (6.36e-2)" "unprognostic (9.68e-2)" "unprognostic (1.01e-1)" "unprognostic (3.13e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "unprognostic (9.28e-3)" "unprognostic (1.33e-3)" "unprognostic (1.74e-2)" "unprognostic (5.40e-2)" "unprognostic (1.43e-1)" "unprognostic (2.31e-1)" "unprognostic (1.45e-2)" STK35 "bA550O8.2, CLIK1" ENSG00000125834 "Serine/threonine kinase 35" Q8TDR2 20 2101827-2177038 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 115.2" "Cell type enriched" "Detected in many" 4 "Late spermatids: 786.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026452, HPA051673" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 36: Late spermatids - Unknown function" 19 "Nucleoplasm, Nuclear bodies" "HPA026452: AB_2671861, HPA051673: AB_2681569" "unprognostic (6.74e-2)" "unprognostic (1.82e-2)" "unprognostic (5.61e-2)" "unprognostic (2.53e-2)" "unprognostic (1.57e-1)" "unprognostic (2.09e-3)" "unprognostic (2.48e-1)" "unprognostic (2.42e-2)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (1.55e-1)" "unprognostic (3.92e-1)" "unprognostic (5.32e-2)" "potential prognostic unfavorable (4.97e-5)" "unprognostic (4.49e-2)" "unprognostic (2.38e-2)" "unprognostic (1.01e-2)" "unprognostic (3.98e-3)" "unprognostic (1.28e-1)" "unprognostic (2.76e-2)" "unprognostic (2.15e-1)" "unprognostic (2.00e-1)" "unprognostic (7.98e-2)" "unprognostic (1.51e-1)" "unprognostic (5.67e-2)" "unprognostic (3.43e-2)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (2.41e-2)" "unprognostic (1.23e-1)" STPG4 "C2orf61, FLJ40172" ENSG00000239605 "Sperm-tail PG-rich repeat containing 4" Q8N801 2 47045538-47155308 "Predicted intracellular proteins" "Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 66 "testis: 14.3" "Group enriched" "Detected in some" 4 "Early spermatids: 65.2;Late spermatids: 57.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 17.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.8" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA047366, HPA052691" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 11: Late spermatids - Unknown function" Nucleoplasm Cytosol "HPA047366: , HPA052691: AB_2681918" "unprognostic (8.05e-2)" "unprognostic (2.58e-1)" STUM "C1orf95, DKFZp761P211" ENSG00000203685 "Stum, mechanosensory transduction mediator homolog" Q69YW2 1 226548764-226609230 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 47.2;intestine: 15.2" "Cell type enhanced" "Detected in some" "Astrocytes: 19.2;Enteroendocrine cells: 7.6;Excitatory neurons: 18.5;Granulosa cells: 7.7;Inhibitory neurons: 6.5;Oligodendrocyte precursor cells: 12.3;Sertoli cells: 8.2;Smooth muscle cells: 8.9" "Cell type enhanced" "Detected in many" "hippocampal CA4: 151.8" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 13.0" "Region enhanced" "Detected in all" "medulla oblongata: 551.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.4;lung cancer: 1.8" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074381 Approved Cytosol NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" 1 Cytosol "HPA074381: AB_2732253" "unprognostic (9.13e-3)" "unprognostic (1.97e-2)" "unprognostic (7.15e-2)" "potential prognostic favorable (7.74e-4)" "unprognostic (2.26e-2)" "potential prognostic favorable (2.93e-4)" "unprognostic (1.68e-1)" "unprognostic (5.75e-2)" "unprognostic (1.58e-3)" "unprognostic (5.32e-3)" "unprognostic (2.63e-1)" "unprognostic (1.15e-2)" "unprognostic (1.87e-2)" "unprognostic (4.39e-1)" "unprognostic (1.64e-2)" "unprognostic (1.22e-2)" STXBP6 "amisyn, HSPC156" ENSG00000168952 "Syntaxin binding protein 6" Q8NFX7 14 24809454-25050147 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "granulocytes: 150.1;Inhibitory neurons: 172.8;Melanocytes: 159.8;Oligodendrocytes: 175.1" "Cell type enhanced" "Detected in many" "endothelial cell: 852.5;hippocampal dentate gyrus: 674.7" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 77.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Endothelial cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003552, HPA074869" Approved NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Neurons - Neuronal signaling" 3 "HPA003552: AB_10603343, HPA074869: " "unprognostic (9.06e-2)" "unprognostic (1.57e-1)" "unprognostic (5.15e-2)" "unprognostic (2.61e-1)" "unprognostic (1.23e-1)" "unprognostic (2.06e-2)" "unprognostic (1.28e-1)" "unprognostic (4.06e-2)" "unprognostic (1.32e-1)" "unprognostic (3.85e-1)" "unprognostic (1.82e-1)" "unprognostic (3.45e-1)" "unprognostic (2.16e-1)" "unprognostic (4.57e-2)" "unprognostic (7.86e-2)" "unprognostic (3.76e-1)" "unprognostic (1.39e-1)" "unprognostic (3.24e-3)" "unprognostic (1.46e-3)" "unprognostic (5.19e-2)" "unprognostic (3.04e-1)" "unprognostic (6.88e-2)" "unprognostic (2.03e-2)" "unprognostic (4.18e-2)" "unprognostic (5.87e-2)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (9.49e-3)" "unprognostic (8.70e-2)" "unprognostic (1.73e-1)" "unprognostic (2.16e-1)" "potential prognostic favorable (5.68e-4)" SULT2B1 HSST2 ENSG00000088002 "Sulfotransferase family 2B member 1" O00204 19 48552172-48599425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 278.0;skin 1: 180.7;vagina: 141.4" "Cell type enriched" "Detected in many" 5 "Suprabasal keratinocytes: 543.6" "Cell type enhanced" "Detected in many" "leukocyte: 6.7" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 90.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041724, HPA043539, HPA076510" Enhanced Enhanced Vesicles,Cytosol NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 59: Suprabasal keratinocytes - Cornification" 11 Vesicles Cytosol "HPA041724: AB_2677638, HPA043539: AB_2678540, HPA076510: " "unprognostic (3.19e-1)" "unprognostic (1.56e-2)" "unprognostic (2.13e-1)" "unprognostic (9.55e-2)" "unprognostic (9.46e-3)" "unprognostic (3.99e-2)" "unprognostic (1.03e-1)" "unprognostic (9.06e-2)" "unprognostic (1.91e-1)" "unprognostic (1.48e-2)" "unprognostic (5.64e-2)" "unprognostic (2.28e-2)" "unprognostic (6.49e-3)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (6.87e-2)" "unprognostic (9.68e-2)" "unprognostic (1.44e-1)" "unprognostic (4.68e-3)" "unprognostic (4.38e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (6.28e-2)" "unprognostic (2.45e-1)" "unprognostic (1.32e-1)" "unprognostic (3.06e-1)" "unprognostic (1.79e-3)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.99e-2)" SYT9 ENSG00000170743 "Synaptotagmin 9" Q86SS6 11 7238778-7469043 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.5;retina: 7.3" "Cell type enhanced" "Detected in some" "Astrocytes: 46.1;Late spermatids: 25.8;Oligodendrocyte precursor cells: 51.9;Oligodendrocytes: 129.6" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 283.2;oligodendrocyte: 249.4;upper rhombic lip: 251.1" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 3.1;Kidney Renal Clear Cell Carcinoma (TCGA): 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Neuroblastoma: 7.6" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Skin - Keratinocyte (other), Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 51: Oligodendrocytes - Unknown function" 6 "unprognostic (8.92e-2)" "unprognostic (7.55e-2)" "unprognostic (5.87e-2)" "validated prognostic favorable (1.74e-6)" "validated prognostic favorable (8.45e-4)" TAFA3 "FAM19A3, TAFA-3" ENSG00000184599 "TAFA chemokine like family member 3" Q7Z5A8 1 112718905-112727235 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 13.2;retina: 44.5" "Cell type enriched" "Detected in some" 4 "Cone photoreceptor cells: 185.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Rhabdoid: 14.0;skin cancer: 4.5" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 21 "olfactory bulb: 3.5" "Low region specificity" "Detected in all" HPA055927 Approved "Secreted in other tissues" "No annotated function" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "HPA055927: AB_2682972" "unprognostic (1.49e-1)" "unprognostic (2.33e-3)" "unprognostic (4.00e-3)" "unprognostic (7.67e-2)" "unprognostic (1.75e-1)" TAFA4 "FAM19A4, TAFA-4" ENSG00000163377 "TAFA chemokine like family member 4" Q96LR4 3 68731766-68953297 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 14.5;brain: 6.9;retina: 10.8;stomach 1: 4.7" "Group enriched" "Detected in some" 4 "Bipolar cells: 35.5;Cone photoreceptor cells: 51.0;Inhibitory neurons: 34.2;Oligodendrocytes: 55.8;Oocytes: 61.0" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 125.9;mammillary body: 330.2;thalamic excitatory: 159.9" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 1.1;Testicular Germ Cell Tumor (TCGA): 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "testis cancer: 2.3" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 5 "thalamus: 13.5" "Low region specificity" "Detected in many" "Secreted in brain" "No annotated function" NA NA "Cluster 76: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 8: Neurons - Neuronal signaling" 1 "unprognostic (1.31e-1)" "unprognostic (3.06e-1)" TBC1D16 "FLJ20748, MGC25062" ENSG00000167291 "TBC1 domain family member 16" Q8TBP0 17 79932343-80035872 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 78.1;Melanocytes: 96.2" "Cell type enhanced" "Detected in all" "fibroblast: 121.6" "Cancer enriched" "Detected in all" 5 "Skin Cuteneous Melanoma (TCGA): 127.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.3" "Lineage enhanced" "Detected in single" "monocytes: 2.3" "Cancer enriched" "Detected in all" 4 "skin cancer: 234.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024482, HPA065839" Approved Approved "Intermediate filaments" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Macrophages - Innate immune response" 2 "Intermediate filaments" "HPA024482: AB_1857790, HPA065839: AB_2685566" "unprognostic (6.91e-2)" "unprognostic (1.88e-1)" "unprognostic (4.30e-3)" "unprognostic (1.53e-2)" "unprognostic (1.02e-1)" "unprognostic (6.56e-2)" "unprognostic (1.50e-3)" "unprognostic (5.69e-2)" "unprognostic (1.09e-1)" "unprognostic (7.38e-2)" "unprognostic (3.81e-3)" "unprognostic (7.14e-3)" "unprognostic (8.07e-2)" "unprognostic (4.08e-3)" "unprognostic (7.39e-3)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (3.45e-4)" "unprognostic (2.16e-1)" "unprognostic (1.27e-1)" "unprognostic (4.17e-2)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (2.88e-1)" "unprognostic (3.76e-1)" "unprognostic (1.92e-3)" "potential prognostic favorable (3.84e-4)" "unprognostic (7.95e-2)" "unprognostic (8.47e-2)" "unprognostic (3.59e-1)" "unprognostic (1.15e-2)" "unprognostic (1.93e-2)" TBC1D22B "C6orf197, dJ744I24.2, FLJ20337" ENSG00000065491 "TBC1 domain family member 22B" Q9NU19 6 37257772-37332970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027908, HPA027909, HPA027910" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 55 "Nucleoplasm, Cytosol" "HPA027908: AB_10602073, HPA027909: AB_10601857, HPA027910: AB_10602203" "unprognostic (4.08e-1)" "unprognostic (5.71e-2)" "unprognostic (9.79e-2)" "unprognostic (5.20e-2)" "unprognostic (1.46e-1)" "unprognostic (3.96e-3)" "unprognostic (3.24e-1)" "unprognostic (1.35e-1)" "unprognostic (1.87e-1)" "unprognostic (4.01e-2)" "validated prognostic favorable (2.10e-6)" "validated prognostic favorable (9.77e-8)" "unprognostic (1.15e-2)" "unprognostic (2.24e-2)" "unprognostic (2.06e-2)" "unprognostic (4.88e-1)" "unprognostic (7.88e-2)" "unprognostic (2.85e-1)" "unprognostic (1.76e-1)" "unprognostic (5.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.97e-2)" "unprognostic (4.79e-3)" "unprognostic (8.92e-2)" "unprognostic (1.26e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-1)" "unprognostic (5.42e-2)" "unprognostic (2.13e-1)" "unprognostic (8.16e-2)" "unprognostic (3.69e-2)" TBK1 NAK ENSG00000183735 "TANK binding kinase 1" Q9UHD2 12 64452090-64502114 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease variant, Glaucoma, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 195.8;Syncytiotrophoblasts: 168.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045797, HPA060211" Uncertain Enhanced Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 4: Testis - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 29: Monocytes - Innate immune response" 141 Nucleoplasm Vesicles "HPA045797: AB_2679457, HPA060211: AB_2684222" "unprognostic (1.28e-2)" "unprognostic (1.13e-2)" "unprognostic (2.38e-1)" "unprognostic (2.14e-2)" "unprognostic (1.45e-2)" "unprognostic (3.43e-3)" "unprognostic (2.68e-1)" "unprognostic (1.47e-1)" "unprognostic (1.65e-1)" "unprognostic (6.36e-2)" "potential prognostic favorable (4.24e-9)" "unprognostic (3.02e-1)" "unprognostic (7.93e-2)" "unprognostic (2.88e-2)" "unprognostic (5.34e-3)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (3.47e-2)" "unprognostic (1.72e-1)" "unprognostic (9.80e-2)" "unprognostic (6.74e-3)" "unprognostic (2.29e-2)" "unprognostic (1.08e-2)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (1.36e-1)" "unprognostic (4.80e-1)" "unprognostic (2.06e-1)" "unprognostic (9.58e-2)" "unprognostic (2.02e-1)" "unprognostic (2.01e-1)" "unprognostic (6.44e-2)" TCF7L2 "TCF-4, TCF4" ENSG00000148737 "Transcription factor 7 like 2" Q9NQB0 10 112950247-113167678 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 251.1;Extravillous trophoblasts: 272.4;monocytes: 328.0" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 873.4;thalamic excitatory: 827.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 379.6" "Group enriched" "Detected in many" 7 "intermediate monocyte: 24.2;non-classical monocyte: 61.8" "Lineage enriched" "Detected in many" 11 "monocytes: 61.8" "Low cancer specificity" "Detected in all" "Spleen - Macrophages" "Group enriched" "Detected in all" 9 "midbrain: 67.2;thalamus: 86.6" "Group enriched" "Detected in all" 4 "midbrain: 194.2;pons: 127.6;thalamus: 215.0" "CAB013535, HPA038800" Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" 35 "Nucleoplasm, Nuclear bodies" Cytosol "CAB013535: AB_2533167, HPA038800: " "potential prognostic favorable (6.22e-4)" "unprognostic (3.34e-2)" "unprognostic (8.87e-2)" "unprognostic (3.62e-2)" "unprognostic (3.36e-1)" "unprognostic (7.42e-2)" "unprognostic (3.11e-2)" "unprognostic (1.02e-1)" "unprognostic (2.87e-1)" "unprognostic (1.50e-1)" "validated prognostic favorable (9.23e-8)" "validated prognostic favorable (2.72e-5)" "unprognostic (2.81e-1)" "unprognostic (2.05e-1)" "unprognostic (8.66e-3)" "unprognostic (1.08e-1)" "unprognostic (5.46e-3)" "unprognostic (8.78e-2)" "unprognostic (2.26e-1)" "unprognostic (5.86e-2)" "unprognostic (1.39e-1)" "unprognostic (5.43e-3)" "unprognostic (1.77e-2)" "unprognostic (6.38e-3)" "unprognostic (3.33e-1)" "unprognostic (3.85e-1)" "unprognostic (1.19e-1)" "unprognostic (2.99e-1)" "unprognostic (1.72e-1)" "unprognostic (1.42e-1)" "unprognostic (7.01e-2)" TESK1 ENSG00000107140 "Testis associated actin remodelling kinase 1" Q15569 9 35605262-35610041 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 33: Non-specific - DNA binding" 7 "unprognostic (3.46e-2)" "unprognostic (2.05e-1)" "unprognostic (8.16e-2)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (3.72e-2)" "unprognostic (6.98e-2)" "unprognostic (7.88e-2)" "unprognostic (2.51e-1)" "unprognostic (9.12e-2)" "potential prognostic favorable (3.47e-5)" "unprognostic (1.02e-1)" "unprognostic (3.23e-1)" "unprognostic (4.56e-3)" "unprognostic (1.38e-1)" "unprognostic (5.90e-2)" "unprognostic (3.98e-3)" "unprognostic (1.93e-2)" "unprognostic (7.22e-2)" "unprognostic (6.74e-2)" "unprognostic (1.30e-3)" "unprognostic (1.16e-1)" "unprognostic (5.34e-2)" "unprognostic (7.66e-2)" "unprognostic (2.69e-3)" "unprognostic (7.78e-2)" "unprognostic (1.78e-1)" "unprognostic (2.81e-2)" "unprognostic (8.06e-2)" "unprognostic (6.84e-2)" "unprognostic (9.92e-2)" THSD4 "ADAMTSL6, FLJ13710, FVSY9334, PRO34005" ENSG00000187720 "Thrombospondin type 1 domain containing 4" Q6ZMP0 15 71096952-71783383 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hydrolase "Aortic aneurysm" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 69.2;esophagus: 58.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 322.0;Microglial cells: 236.2;Secretory cells: 90.6;Squamous epithelial cells: 110.0" "Group enriched" "Detected in all" 4 "endothelial cell: 1745.1;fibroblast: 1030.1" "Cancer enhanced" "Detected in all" "Ovary Serous Cystadenocarcinoma (TCGA): 64.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 52.3" "Secreted - unknown location" Enzyme NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 20 "unprognostic (2.25e-1)" "unprognostic (1.62e-1)" "unprognostic (5.60e-1)" "unprognostic (6.46e-3)" "unprognostic (8.77e-2)" "unprognostic (1.71e-1)" "unprognostic (1.53e-1)" "unprognostic (7.49e-2)" "unprognostic (2.08e-2)" "unprognostic (1.47e-1)" "unprognostic (3.79e-1)" "unprognostic (3.40e-2)" "unprognostic (6.91e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-1)" "unprognostic (2.61e-1)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "unprognostic (2.27e-1)" "unprognostic (1.09e-2)" "unprognostic (4.98e-1)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (1.12e-1)" "unprognostic (2.05e-2)" "unprognostic (2.04e-1)" "unprognostic (3.02e-2)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.81e-3)" "unprognostic (2.26e-1)" TINCR "FLJ90734, LINC00036, NCRNA00036, onco-lncRNA-16, PLAC2" ENSG00000223573 "TINCR ubiquitin domain containing" A0A2R8Y7D0 19 5558167-5578349 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 117.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 160.8;Extravillous trophoblasts: 320.6;Suprabasal keratinocytes: 127.7;Syncytiotrophoblasts: 631.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 26.0;cervical cancer: 23.2" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "unprognostic (2.95e-3)" "unprognostic (7.95e-3)" "unprognostic (6.10e-2)" "unprognostic (1.72e-1)" "unprognostic (1.20e-1)" "unprognostic (1.35e-1)" "unprognostic (2.14e-3)" "unprognostic (3.33e-3)" "unprognostic (1.61e-2)" "potential prognostic unfavorable (2.63e-5)" "unprognostic (1.38e-1)" "unprognostic (2.72e-1)" "unprognostic (2.06e-1)" "unprognostic (9.39e-2)" "unprognostic (1.73e-2)" "unprognostic (5.65e-2)" "unprognostic (8.69e-3)" "unprognostic (2.56e-1)" "unprognostic (3.18e-3)" "unprognostic (8.36e-2)" "unprognostic (3.02e-1)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (9.52e-2)" "unprognostic (1.82e-1)" TLK1 "KIAA0137, PKU-BETA" ENSG00000198586 "Tousled like kinase 1" Q9UKI8 2 170990823-171231314 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016043 Approved Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 65: Neurons - Synaptic function" 30 Nucleoplasm "HPA016043: AB_1858027" "unprognostic (1.81e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (1.10e-1)" "unprognostic (2.71e-1)" "unprognostic (1.44e-1)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (1.18e-1)" "unprognostic (1.26e-1)" "potential prognostic favorable (5.53e-5)" "unprognostic (7.40e-2)" "unprognostic (2.45e-1)" "unprognostic (2.18e-2)" "unprognostic (8.94e-2)" "unprognostic (9.89e-2)" "unprognostic (9.25e-2)" "unprognostic (3.73e-3)" "unprognostic (2.05e-1)" "unprognostic (1.41e-1)" "unprognostic (5.16e-2)" "unprognostic (8.31e-2)" "unprognostic (3.44e-3)" "unprognostic (6.16e-2)" "unprognostic (1.45e-1)" "unprognostic (6.47e-2)" "unprognostic (4.82e-2)" "unprognostic (1.64e-1)" "unprognostic (2.47e-1)" "unprognostic (3.08e-2)" "unprognostic (2.83e-2)" TMEM108 "CT124, MGC3040" ENSG00000144868 "Transmembrane protein 108" Q6UXF1 3 133038391-133397775 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 33.8;skeletal muscle: 22.3" "Group enriched" "Detected in many" 4 "Astrocytes: 199.1;Excitatory neurons: 345.5;Inhibitory neurons: 456.7;Oligodendrocyte precursor cells: 450.4" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 4143.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 21.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 9 "Neuroblastoma: 56.7" "Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063350 Uncertain Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 30000 "Cluster 3: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" 3 "Plasma membrane, Cytosol" "Nucleoli, Vesicles" "HPA063350: AB_2684993" "unprognostic (3.12e-3)" "unprognostic (1.64e-2)" "unprognostic (1.74e-1)" "unprognostic (1.47e-2)" "unprognostic (2.75e-2)" "unprognostic (2.18e-1)" "unprognostic (2.05e-1)" "unprognostic (2.49e-1)" "potential prognostic favorable (7.23e-4)" "unprognostic (4.65e-2)" "unprognostic (4.11e-3)" "unprognostic (3.34e-1)" "unprognostic (2.94e-1)" "unprognostic (4.55e-1)" "unprognostic (1.50e-1)" "potential prognostic favorable (3.82e-5)" "unprognostic (1.57e-3)" "unprognostic (2.14e-1)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" TMEM127 "FLJ20507, FLJ22257" ENSG00000135956 "Transmembrane protein 127" O75204 2 96248514-96265997 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 56: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 58: Macrophages - Innate immune response" "unprognostic (1.77e-2)" "unprognostic (2.20e-3)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (2.49e-1)" "unprognostic (4.57e-2)" "unprognostic (2.90e-1)" "unprognostic (1.16e-3)" "unprognostic (2.68e-1)" "unprognostic (2.41e-1)" "potential prognostic favorable (1.09e-6)" "unprognostic (1.78e-3)" "unprognostic (4.67e-2)" "unprognostic (3.71e-3)" "unprognostic (1.45e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-3)" "unprognostic (7.29e-2)" "unprognostic (1.85e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-3)" "unprognostic (8.89e-2)" "unprognostic (6.64e-2)" "unprognostic (1.79e-1)" "unprognostic (4.42e-2)" "unprognostic (1.49e-1)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.48e-1)" "unprognostic (2.76e-1)" TMEM163 "DKFZP566N034, SV31" ENSG00000152128 "Transmembrane protein 163" Q8TC26 2 134455759-134719000 "Predicted membrane proteins, Transporters" Transport "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.4;pancreas: 27.0" "Group enriched" "Detected in many" 5 "Alveolar cells type 2: 54.1;Excitatory neurons: 60.1;Oligodendrocyte precursor cells: 206.1;Oocytes: 193.4" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 706.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 16.3" "Lung - Alveolar cells type 2, Skin - Outer root sheath cells, Spleen - B-cells (Spleen), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007224 Uncertain NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 76: Oligodendrocyte precursor - Unknown function" 4 "HPA007224: AB_2667780" "unprognostic (9.00e-3)" "unprognostic (4.22e-2)" "unprognostic (1.04e-2)" "unprognostic (9.64e-2)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.51e-2)" "unprognostic (1.74e-1)" "unprognostic (4.40e-2)" "unprognostic (1.97e-2)" "unprognostic (3.16e-2)" "potential prognostic favorable (9.64e-4)" "unprognostic (8.36e-3)" "unprognostic (8.90e-2)" "validated prognostic favorable (3.34e-4)" "validated prognostic favorable (3.62e-4)" "unprognostic (3.63e-1)" "unprognostic (4.23e-1)" "unprognostic (2.09e-2)" "unprognostic (1.24e-2)" "unprognostic (1.00e-1)" "unprognostic (3.30e-2)" "unprognostic (1.54e-2)" "unprognostic (3.57e-1)" "unprognostic (2.19e-2)" "unprognostic (3.38e-1)" "unprognostic (7.53e-2)" "unprognostic (5.82e-3)" "unprognostic (3.91e-2)" TMEM164 "FLJ22679, RP13-360B22.2" ENSG00000157600 "Transmembrane protein 164" Q5U3C3 X 110002631-110182734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 43.9;Astrocytes: 80.2;Distal enterocytes: 49.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 59.8" "Lineage enriched" "Detected in many" 18 "granulocytes: 59.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038784 Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 38: Sub-cortical - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 47: Astrocytes - Unknown function" Vesicles "Cell Junctions" "HPA038784: AB_10670790" "unprognostic (3.01e-1)" "unprognostic (2.26e-2)" "unprognostic (8.14e-2)" "unprognostic (5.65e-2)" "unprognostic (3.44e-2)" "unprognostic (7.24e-2)" "unprognostic (4.00e-2)" "unprognostic (2.01e-2)" "unprognostic (1.28e-2)" "unprognostic (5.65e-2)" "unprognostic (2.72e-2)" "unprognostic (2.04e-1)" "unprognostic (2.09e-2)" "validated prognostic unfavorable (9.08e-5)" "validated prognostic unfavorable (8.10e-4)" "unprognostic (6.20e-3)" "unprognostic (7.36e-2)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (5.14e-2)" "unprognostic (2.06e-1)" "unprognostic (2.29e-1)" "unprognostic (4.19e-2)" "unprognostic (2.42e-1)" "unprognostic (1.44e-1)" "potential prognostic favorable (7.86e-4)" "unprognostic (1.63e-1)" "unprognostic (1.40e-3)" "unprognostic (1.92e-1)" TMEM177 MGC10993 ENSG00000144120 "Transmembrane protein 177" Q53S58 2 119679167-119686507 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 34.0;Distal tubular cells: 43.0;Proximal tubular cells: 47.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036689, HPA053816" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 2 "Nucleoplasm, Nucleoli fibrillar center" "HPA036689: AB_2675253, HPA053816: AB_2682272" "unprognostic (3.13e-1)" "unprognostic (2.82e-2)" "unprognostic (3.49e-1)" "unprognostic (3.15e-2)" "unprognostic (3.81e-2)" "unprognostic (1.27e-2)" "unprognostic (1.49e-3)" "unprognostic (9.13e-3)" "unprognostic (1.53e-3)" "unprognostic (2.48e-1)" "unprognostic (6.08e-2)" "unprognostic (9.67e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-3)" "unprognostic (2.76e-2)" "unprognostic (2.71e-2)" "unprognostic (6.85e-2)" "unprognostic (3.85e-2)" "unprognostic (2.15e-2)" "unprognostic (8.07e-2)" "unprognostic (1.91e-1)" "unprognostic (2.68e-1)" "unprognostic (2.98e-1)" "unprognostic (2.37e-1)" "unprognostic (3.30e-2)" "unprognostic (1.73e-1)" "unprognostic (3.61e-1)" "unprognostic (1.67e-1)" "unprognostic (5.38e-2)" "unprognostic (2.24e-1)" "unprognostic (8.94e-2)" TMEM178B DKFZp547G036 ENSG00000261115 "Transmembrane protein 178B" H3BS89 7 141074064-141480380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;heart muscle: 10.2;parathyroid gland: 11.5;tongue: 11.6" "Group enriched" "Detected in many" 5 "Astrocytes: 166.0;Excitatory neurons: 565.6;Inhibitory neurons: 542.7;Oligodendrocyte precursor cells: 287.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 8.7;Kidney Renal Papillary Cell Carcinoma (TCGA): 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048771 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" Vesicles Nucleoli "HPA048771: AB_2680517" "unprognostic (1.49e-3)" "unprognostic (7.50e-2)" "unprognostic (1.96e-1)" "unprognostic (4.10e-1)" "unprognostic (3.18e-1)" "unprognostic (2.43e-1)" "unprognostic (1.07e-1)" "unprognostic (8.87e-2)" "unprognostic (8.43e-3)" "unprognostic (1.87e-1)" "unprognostic (8.48e-2)" "potential prognostic favorable (5.58e-4)" "unprognostic (8.23e-2)" "unprognostic (2.38e-1)" "unprognostic (9.28e-2)" "unprognostic (2.36e-1)" "unprognostic (1.69e-2)" TMEM26 "Em:AC068892.1, MGC35010" ENSG00000196932 "Transmembrane protein 26" Q6ZUK4 10 61406642-61453381 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 6.4;Early spermatids: 5.0;Endometrial stromal cells: 5.1;Excitatory neurons: 5.1;Inhibitory neurons: 4.6;Kupffer cells: 10.3;Late spermatids: 5.0;Sertoli cells: 5.4" "Cell type enhanced" "Detected in many" "thalamic excitatory: 38.1" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5;Rhabdoid: 2.0" "Breast - Breast glandular cells, Liver - Kupffer cells, Pituitary gland - Fibroblasts" "Region enhanced" "Detected in some" "hypothalamus: 2.3" "Low region specificity" "Detected in all" NA NA "Cluster 47: Spleen - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "unprognostic (5.24e-3)" "unprognostic (3.39e-1)" "unprognostic (3.45e-2)" "unprognostic (2.61e-2)" "unprognostic (1.11e-2)" "unprognostic (6.40e-2)" "unprognostic (2.57e-2)" "unprognostic (5.18e-1)" "unprognostic (1.17e-2)" "unprognostic (1.80e-1)" "unprognostic (2.82e-1)" "unprognostic (2.91e-1)" "unprognostic (6.78e-2)" TMEM37 "PR, PR1" ENSG00000171227 "Transmembrane protein 37" Q8WXS4 2 119429901-119438504 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 97.4;liver: 97.6;parathyroid gland: 120.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 127.4;Hepatocytes: 176.6;Muller glia cells: 131.8;Proximal enterocytes: 530.6;Proximal tubular cells: 173.8;Syncytiotrophoblasts: 130.7" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.6;endothelial cell: 7.6;fibroblast: 4.2" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 165.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 32.2" "Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA053794, HPA076947" Enhanced Approved "Golgi apparatus" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" "Golgi apparatus" "HPA053794: AB_2682265, HPA076947: " "unprognostic (6.57e-2)" "unprognostic (4.06e-2)" "unprognostic (2.56e-3)" "unprognostic (4.62e-2)" "unprognostic (2.29e-1)" "unprognostic (1.88e-1)" "unprognostic (6.49e-2)" "unprognostic (7.57e-2)" "unprognostic (1.60e-1)" "unprognostic (8.30e-2)" "validated prognostic favorable (7.25e-10)" "validated prognostic favorable (2.23e-4)" "unprognostic (1.12e-1)" "unprognostic (8.79e-2)" "unprognostic (3.33e-3)" "unprognostic (1.04e-1)" "unprognostic (4.70e-2)" "unprognostic (9.29e-2)" "unprognostic (4.06e-1)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" "unprognostic (8.72e-2)" "unprognostic (6.79e-2)" "unprognostic (1.01e-1)" "unprognostic (1.96e-1)" "unprognostic (1.49e-1)" "unprognostic (7.46e-3)" "unprognostic (4.62e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" TMEM41A MGC15397 ENSG00000163900 "Transmembrane protein 41A" Q96HV5 3 185476496-185499057 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 189.6;Squamous epithelial cells: 121.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "HPA059101, HPA059790" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 22: Proximal enterocytes - Digestion" 7 Nucleoplasm "Golgi apparatus, Cytosol" "HPA059101: AB_2683905, HPA059790: AB_2684125" "unprognostic (8.90e-3)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (5.14e-2)" "unprognostic (2.80e-1)" "unprognostic (1.62e-2)" "unprognostic (1.61e-1)" "unprognostic (1.61e-1)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (3.40e-2)" "unprognostic (2.36e-2)" "unprognostic (2.16e-1)" "unprognostic (8.10e-2)" "validated prognostic unfavorable (6.44e-4)" "validated prognostic unfavorable (4.74e-4)" "potential prognostic unfavorable (9.38e-4)" "unprognostic (9.59e-3)" "unprognostic (1.40e-2)" "unprognostic (6.09e-3)" "unprognostic (3.73e-1)" "unprognostic (8.45e-2)" "validated prognostic unfavorable (1.01e-4)" "validated prognostic unfavorable (4.53e-4)" "unprognostic (9.93e-3)" "unprognostic (8.66e-2)" "unprognostic (4.36e-1)" "unprognostic (3.77e-1)" "unprognostic (1.93e-1)" "unprognostic (3.76e-1)" "unprognostic (5.72e-2)" "unprognostic (4.39e-2)" TMEM50B C21orf4 ENSG00000142188 "Transmembrane protein 50B" P56557 21 33432485-33479974 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034199, HPA068995" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 18 "Nucleoli fibrillar center" "CAB034199: AB_2205160, HPA068995: AB_2686066" "unprognostic (6.72e-3)" "unprognostic (2.78e-2)" "unprognostic (1.18e-1)" "unprognostic (2.97e-1)" "unprognostic (8.62e-3)" "unprognostic (9.65e-2)" "unprognostic (8.09e-2)" "unprognostic (5.13e-3)" "unprognostic (2.07e-1)" "unprognostic (6.66e-2)" "potential prognostic favorable (1.43e-8)" "unprognostic (1.84e-3)" "unprognostic (3.27e-2)" "unprognostic (2.50e-2)" "unprognostic (3.88e-3)" "potential prognostic favorable (2.79e-5)" "unprognostic (1.19e-1)" "unprognostic (4.20e-1)" "unprognostic (2.79e-1)" "unprognostic (4.09e-1)" "unprognostic (1.77e-1)" "unprognostic (3.00e-1)" "unprognostic (2.90e-2)" "unprognostic (3.12e-1)" "unprognostic (1.71e-2)" "unprognostic (1.28e-1)" "unprognostic (1.95e-2)" "unprognostic (4.30e-2)" "unprognostic (6.07e-2)" "unprognostic (1.19e-2)" "unprognostic (1.23e-2)" TMEM65 ENSG00000164983 "Transmembrane protein 65" Q6PI78 8 124306189-124372701 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.3;Inhibitory neurons: 134.1;Microglial cells: 67.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007108, HPA025020" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 35: Non-specific - Mitochondria" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 29 "Vesicles, Plasma membrane" "HPA007108: , HPA025020: AB_2205178" "unprognostic (2.94e-2)" "unprognostic (2.17e-3)" "unprognostic (2.55e-2)" "unprognostic (7.42e-3)" "unprognostic (2.52e-1)" "unprognostic (1.87e-3)" "unprognostic (1.31e-1)" "unprognostic (2.40e-1)" "unprognostic (7.20e-2)" "unprognostic (4.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.41e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (8.33e-5)" "unprognostic (9.46e-3)" "unprognostic (1.85e-3)" "unprognostic (1.22e-2)" "unprognostic (3.52e-2)" "unprognostic (1.14e-1)" "unprognostic (2.61e-1)" "unprognostic (3.87e-2)" "unprognostic (4.80e-2)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (3.81e-2)" "unprognostic (2.04e-1)" "unprognostic (1.23e-2)" "unprognostic (1.12e-1)" "unprognostic (5.41e-2)" "unprognostic (5.92e-2)" "unprognostic (4.74e-2)" "unprognostic (1.63e-1)" TMEM8B "C9orf127, FP588, LINC00950, NAG-5, NGX6, NGX6a" ENSG00000137103 "Transmembrane protein 8B" A6NDV4 9 35814451-35865518 "Predicted membrane proteins, Transporters" "Cell adhesion, Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 68.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 51.3" "Lineage enriched" "Detected in many" 24 "dendritic cells: 51.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052130, HPA062701" Approved Approved Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" Vesicles "HPA052130: AB_2681740, HPA062701: AB_2684839" "unprognostic (3.34e-3)" "unprognostic (4.12e-2)" "unprognostic (1.74e-1)" "unprognostic (8.53e-2)" "unprognostic (2.29e-1)" "unprognostic (3.22e-1)" "unprognostic (3.54e-1)" "unprognostic (9.72e-2)" "unprognostic (5.84e-2)" "unprognostic (2.67e-1)" "potential prognostic favorable (2.13e-7)" "unprognostic (1.08e-2)" "potential prognostic favorable (8.81e-5)" "unprognostic (3.58e-2)" "unprognostic (6.57e-2)" "unprognostic (8.00e-3)" "unprognostic (4.23e-1)" "unprognostic (8.02e-2)" "unprognostic (8.75e-2)" "unprognostic (2.25e-1)" "unprognostic (1.04e-2)" "potential prognostic favorable (3.37e-4)" "unprognostic (2.62e-2)" "unprognostic (1.12e-1)" "unprognostic (4.43e-2)" "unprognostic (2.90e-1)" "unprognostic (2.68e-1)" "unprognostic (1.77e-1)" "unprognostic (7.76e-2)" "unprognostic (1.26e-2)" "unprognostic (3.22e-2)" TMTC1 "ARG99, FLJ31400, FLJ41625, OLF" ENSG00000133687 "Transmembrane O-mannosyltransferase targeting cadherins 1" Q8IUR5 12 29500840-29784759 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 102.0;Astrocytes: 61.3;Endothelial cells: 84.6;Excitatory neurons: 180.1;Inhibitory neurons: 191.9;Skeletal myocytes: 59.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016720 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 8: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA016720: AB_1858155" "unprognostic (3.87e-2)" "unprognostic (2.89e-1)" "unprognostic (6.78e-2)" "unprognostic (6.21e-2)" "unprognostic (1.06e-1)" "unprognostic (3.67e-2)" "unprognostic (4.21e-2)" "unprognostic (4.51e-2)" "unprognostic (8.41e-2)" "unprognostic (2.91e-1)" "potential prognostic favorable (1.85e-9)" "unprognostic (2.30e-3)" "unprognostic (1.12e-3)" "unprognostic (8.36e-2)" "unprognostic (2.26e-1)" "unprognostic (4.15e-1)" "unprognostic (1.03e-1)" "unprognostic (7.95e-3)" "unprognostic (1.20e-2)" "unprognostic (3.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.56e-2)" "unprognostic (3.36e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (4.12e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "unprognostic (1.30e-1)" TP53I3 PIG3 ENSG00000115129 "Tumor protein p53 inducible protein 3" Q53FA7 2 24077433-24085861 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 115.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.7;Distal enterocytes: 184.0;Late spermatids: 218.2;Proximal enterocytes: 197.8" "Cell type enhanced" "Detected in many" "bergmann glia: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "CAB017479, HPA022012, HPA028742" Enhanced Supported Vesicles NA NA 190000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 5: Enterocytes - Absorption" 3 Vesicles "CAB017479: AB_2303667, HPA022012: AB_1858202, HPA028742: AB_10603456" "unprognostic (5.14e-2)" "unprognostic (8.83e-2)" "unprognostic (3.54e-2)" "unprognostic (6.39e-3)" "unprognostic (1.67e-2)" "unprognostic (9.75e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-2)" "unprognostic (3.74e-1)" "unprognostic (3.16e-1)" "unprognostic (1.23e-3)" "unprognostic (1.13e-1)" "unprognostic (1.34e-3)" "unprognostic (3.01e-2)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (3.32e-4)" "unprognostic (3.39e-1)" "unprognostic (1.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.67e-1)" "unprognostic (3.66e-3)" "unprognostic (7.76e-2)" "unprognostic (1.23e-1)" "unprognostic (4.24e-3)" "unprognostic (2.40e-2)" "unprognostic (3.14e-2)" "unprognostic (6.01e-2)" "unprognostic (1.15e-1)" "unprognostic (2.16e-2)" "unprognostic (1.45e-2)" TRAPPC1 "BET5, MUM2" ENSG00000170043 "Trafficking protein particle complex subunit 1" Q9Y5R8 17 7930345-7932123 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 577.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Mitotic cells (Minor salivary gland), Stomach - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA052398 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 38: Proximal tubular cells - Transmembrane transport" 62 "HPA052398: AB_2681813" "unprognostic (3.02e-3)" "unprognostic (1.17e-1)" "unprognostic (3.81e-3)" "unprognostic (1.38e-2)" "unprognostic (9.84e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (3.14e-5)" "unprognostic (4.37e-2)" "unprognostic (2.84e-3)" "unprognostic (6.80e-3)" "unprognostic (1.14e-2)" "unprognostic (2.32e-1)" "unprognostic (8.19e-3)" "unprognostic (6.42e-2)" "unprognostic (4.13e-2)" "unprognostic (1.29e-1)" "unprognostic (2.85e-1)" "unprognostic (2.87e-2)" "unprognostic (7.88e-2)" "unprognostic (2.43e-2)" "unprognostic (5.32e-2)" "unprognostic (2.95e-2)" "unprognostic (9.01e-2)" "unprognostic (5.47e-2)" "unprognostic (2.85e-3)" "unprognostic (1.39e-1)" "unprognostic (2.39e-1)" "unprognostic (2.25e-2)" "unprognostic (2.00e-1)" "unprognostic (3.27e-1)" "unprognostic (1.31e-1)" TRAV24 ENSG00000211805 "T cell receptor alpha variable 24" A0A0B4J272 14 22105343-22105846 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 20.8" "Cell type enriched" "Detected in single" 8 "T-cells: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 24 "memory CD4 T-cell: 24.5;memory CD8 T-cell: 47.5;naive CD4 T-cell: 22.5;naive CD8 T-cell: 66.8;T-reg: 41.1" "Lineage enriched" "Detected in single" 242 "T-cells: 66.8" "Not detected" "Not detected" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" "unprognostic (4.82e-2)" "unprognostic (2.77e-1)" "unprognostic (8.08e-2)" "unprognostic (1.68e-2)" "unprognostic (4.72e-2)" TRAV3 ENSG00000211777 "T cell receptor alpha variable 3" A0A0B4J244 14 21723713-21724321 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 9.8" "Cell type enriched" "Detected in some" 5 "T-cells: 6.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 48.9;memory CD8 T-cell: 33.6;naive CD4 T-cell: 51.3;naive CD8 T-cell: 48.0;T-reg: 113.1" "Lineage enriched" "Detected in single" 144 "T-cells: 113.1" "Group enriched" "Detected in some" 20 "Bone cancer: 14.6;Leukemia: 10.8" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" "unprognostic (5.46e-3)" "unprognostic (4.87e-2)" "unprognostic (1.13e-1)" "potential prognostic favorable (1.88e-4)" "unprognostic (1.75e-1)" "unprognostic (3.05e-1)" "unprognostic (9.35e-2)" "unprognostic (2.24e-1)" "unprognostic (1.14e-1)" TRAV6 TCRAV5S1 ENSG00000211780 "T cell receptor alpha variable 6" A0A075B6T7 14 21768489-21769080 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 10.9" "Group enriched" "Detected in some" 16 "dendritic cells: 2.0;T-cells: 4.4" "Cell type enriched" "Detected in single" 39 "leukocyte: 3.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 70 "MAIT T-cell: 17.1;memory CD4 T-cell: 33.8;memory CD8 T-cell: 19.0;naive CD4 T-cell: 26.4;naive CD8 T-cell: 16.3;T-reg: 59.8" "Lineage enriched" "Detected in single" 145 "T-cells: 59.8" "Group enriched" "Detected in some" 18 "Bone cancer: 6.6;Leukemia: 1.7" "Breast - T-cells" "Not detected" "Not detected" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 7: T-cells - T-cell receptor" "unprognostic (5.50e-2)" "unprognostic (1.62e-1)" "unprognostic (2.26e-1)" "unprognostic (2.81e-1)" "unprognostic (7.62e-2)" TRBJ2-1 "TCRBJ2S1, TRBJ21" ENSG00000211764 "T cell receptor beta joining 2-1" A0A0A0MTA7 7 142796365-142796414 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "bone marrow: 26.7;lymphoid tissue: 65.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 19.7" "Immune cell enhanced" "Detected in all" "T-reg: 1690.7" "Lineage enriched" "Detected in all" 8 "T-cells: 1690.7" "Cancer enriched" "Detected in many" 4 "Leukemia: 82.2" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" "unprognostic (3.88e-1)" "unprognostic (3.91e-2)" "unprognostic (2.04e-1)" "unprognostic (7.47e-2)" "unprognostic (1.78e-1)" "unprognostic (2.51e-3)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (5.78e-1)" "unprognostic (2.92e-1)" "unprognostic (8.91e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (7.11e-2)" "unprognostic (1.38e-1)" "unprognostic (2.69e-1)" "unprognostic (6.17e-1)" "unprognostic (7.22e-2)" "unprognostic (1.08e-2)" "unprognostic (1.16e-2)" TRBJ2-2 "TCRBJ2S2, TRBJ22" ENSG00000211765 "T cell receptor beta joining 2-2" 7 142796560-142796610 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 19.3;lymphoid tissue: 30.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "MAIT T-cell: 521.7;memory CD4 T-cell: 336.7;memory CD8 T-cell: 332.9;naive CD4 T-cell: 389.5;naive CD8 T-cell: 325.2;T-reg: 724.2" "Lineage enriched" "Detected in all" 12 "T-cells: 724.2" "Cancer enriched" "Detected in some" 4 "Leukemia: 19.7" "Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" "unprognostic (2.21e-2)" "unprognostic (1.32e-1)" "unprognostic (1.41e-1)" "unprognostic (9.61e-2)" "unprognostic (1.28e-1)" "unprognostic (2.86e-1)" "unprognostic (7.94e-2)" "unprognostic (1.56e-1)" "unprognostic (3.26e-1)" "unprognostic (5.01e-1)" "unprognostic (4.67e-1)" TRBJ2-2P TRBJ22P ENSG00000211766 "T cell receptor beta joining 2-2P (non-functional)" 7 142796697-142796742 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 17.1;intestine: 11.9;lymphoid tissue: 34.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 28 "gdT-cell: 1438.8;MAIT T-cell: 471.3;memory B-cell: 1305.9;memory CD4 T-cell: 570.4;memory CD8 T-cell: 549.2;naive B-cell: 1403.5;naive CD4 T-cell: 517.8;naive CD8 T-cell: 583.7;NK-cell: 993.0;T-reg: 1286.1" "Group enriched" "Detected in all" 40 "B-cells: 1403.5;NK-cells: 993.0;T-cells: 1438.8" "Group enriched" "Detected in many" 6 "Leukemia: 33.8;lymphoma: 37.1;Myeloma: 13.7" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (8.01e-1)" "unprognostic (1.14e-1)" "unprognostic (4.69e-1)" "unprognostic (2.31e-1)" "unprognostic (6.72e-2)" "potential prognostic favorable (1.66e-4)" "potential prognostic favorable (9.17e-4)" "unprognostic (9.61e-2)" "unprognostic (3.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.73e-1)" "unprognostic (1.62e-1)" "unprognostic (1.33e-1)" "unprognostic (5.23e-2)" "unprognostic (6.28e-1)" "unprognostic (7.49e-2)" "unprognostic (1.18e-1)" "unprognostic (5.98e-2)" "unprognostic (3.52e-2)" TRBJ2-3 "TCRBJ2S3, TRBJ23" ENSG00000211767 "T cell receptor beta joining 2-3" A0A0B4J200 7 142796847-142796895 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 84.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 42.8" "Group enriched" "Detected in all" 12 "gdT-cell: 1491.2;MAIT T-cell: 910.2;memory B-cell: 1213.3;memory CD4 T-cell: 1125.9;memory CD8 T-cell: 1157.0;naive B-cell: 1432.5;naive CD4 T-cell: 1108.3;naive CD8 T-cell: 1034.7;NK-cell: 937.1;T-reg: 2323.3" "Group enriched" "Detected in all" 15 "B-cells: 1432.5;NK-cells: 937.1;T-cells: 2323.3" "Group enriched" "Detected in many" 6 "Leukemia: 77.1;lymphoma: 122.5;Myeloma: 45.1" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" "unprognostic (5.34e-1)" "unprognostic (2.17e-3)" "unprognostic (1.12e-1)" "unprognostic (8.93e-2)" "unprognostic (2.42e-1)" "unprognostic (2.40e-3)" "potential prognostic favorable (7.53e-4)" "unprognostic (4.20e-1)" "unprognostic (4.71e-2)" "unprognostic (1.16e-2)" "unprognostic (1.16e-1)" "unprognostic (3.07e-2)" "unprognostic (5.14e-2)" "unprognostic (3.43e-3)" "unprognostic (1.91e-1)" "unprognostic (7.06e-2)" "unprognostic (2.19e-1)" "unprognostic (2.98e-1)" "unprognostic (3.35e-1)" "unprognostic (1.89e-2)" "unprognostic (1.98e-2)" "unprognostic (1.36e-1)" "unprognostic (1.90e-1)" "unprognostic (5.09e-2)" "unprognostic (2.22e-1)" TRBJ2-4 "TCRBJ2S4, TRBJ24" ENSG00000211768 "T cell receptor beta joining 2-4" 7 142796998-142797047 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 9.0;lymphoid tissue: 18.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 5.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 21.5;lymphoma: 16.8;Myeloma: 6.0" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (5.93e-2)" "unprognostic (2.79e-1)" "unprognostic (1.81e-2)" "unprognostic (1.76e-1)" "unprognostic (1.55e-1)" "unprognostic (4.20e-1)" "unprognostic (8.48e-2)" "unprognostic (1.78e-1)" TRBJ2-6 "TCRBJ2S6, TRBJ26" ENSG00000211770 "T cell receptor beta joining 2-6" 7 142797239-142797291 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 10.0;lymphoid tissue: 24.1;stomach 1: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 52.6;lymphoma: 15.2" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.47e-1)" "unprognostic (2.40e-1)" "unprognostic (4.33e-1)" "unprognostic (8.60e-2)" "unprognostic (1.20e-1)" "unprognostic (1.35e-2)" TRBJ2-7 "TCRBJ2S7, TRBJ27" ENSG00000211771 "T cell receptor beta joining 2-7" A0A0A0MT78 7 142797456-142797502 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 46.4;lymphoid tissue: 144.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "MAIT T-cell: 1278.7;memory CD4 T-cell: 2394.0;memory CD8 T-cell: 2654.4;naive CD4 T-cell: 2400.3;naive CD8 T-cell: 2837.5;T-reg: 4232.8" "Lineage enriched" "Detected in all" 18 "T-cells: 4232.8" "Cancer enhanced" "Detected in many" "Leukemia: 87.0;lymphoma: 25.0" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" "unprognostic (5.42e-1)" "unprognostic (1.75e-2)" "unprognostic (6.78e-2)" "unprognostic (1.67e-1)" "unprognostic (2.89e-2)" "unprognostic (2.43e-3)" "unprognostic (4.91e-2)" "unprognostic (7.47e-2)" "unprognostic (3.61e-1)" "unprognostic (3.88e-1)" "unprognostic (4.31e-2)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" "unprognostic (5.52e-1)" "unprognostic (3.61e-2)" "unprognostic (4.70e-2)" "unprognostic (1.38e-2)" "unprognostic (1.54e-1)" "unprognostic (1.84e-1)" "unprognostic (1.77e-1)" "unprognostic (6.28e-2)" "unprognostic (1.80e-1)" UBL4B FLJ25690 ENSG00000186150 "Ubiquitin like 4B" Q8N7F7 1 110112443-110113947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "testis: 102.0" "Cell type enriched" "Detected in some" 5 "Late spermatids: 6536.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Fibroblasts, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031364 Enhanced NA NA "Cluster 20: Testis - Spermatogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Late spermatids - Unknown function" 7 "HPA031364: AB_10604000" "unprognostic (2.15e-2)" "unprognostic (4.35e-3)" UPK3B "FLJ32198, MGC10902, p35, UPIIIb" ENSG00000243566 "Uroplakin 3B" Q9BT76 7 76510525-76516522 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 116.7;esophagus: 63.0;lung: 48.4;urinary bladder: 40.9" "Cell type enriched" "Detected in some" 12 "Mesothelial cells: 1046.6" "Cell type enriched" "Detected in some" 4 "choroid plexus epithelial cell: 6.4" "Group enriched" "Detected in many" 11 "Bladder Urothelial Carcinoma (TCGA): 51.7;Ovary Serous Cystadenocarcinoma (TCGA): 53.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 49.5" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary gland basal cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA010506 Approved NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" "HPA010506: AB_1080479" "unprognostic (1.04e-3)" "unprognostic (2.74e-1)" "unprognostic (2.66e-2)" "unprognostic (5.30e-2)" "unprognostic (4.10e-3)" "unprognostic (2.46e-1)" "unprognostic (5.50e-2)" "unprognostic (1.62e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.48e-3)" "unprognostic (2.19e-2)" "unprognostic (7.50e-3)" "unprognostic (2.45e-2)" "unprognostic (2.99e-2)" "unprognostic (2.19e-2)" UXS1 "FLJ23591, SDR6E1, UGD" ENSG00000115652 "UDP-glucuronate decarboxylase 1" Q8NBZ7 2 106093308-106194301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 111.5;Early spermatids: 110.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Alveolar cells type 1, Spleen - Fibroblast_1, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008825 Uncertain "Intracellular and membrane" Enzyme NA NA 17000 "Cluster 6: T-cells - T-cell receptor" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Platelets - Hemostasis" 1 "HPA008825: AB_1858708" "unprognostic (2.37e-1)" "unprognostic (1.69e-1)" "unprognostic (4.71e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-1)" "unprognostic (6.63e-2)" "unprognostic (3.32e-1)" "unprognostic (5.29e-2)" "unprognostic (4.84e-3)" "unprognostic (8.54e-2)" "potential prognostic favorable (4.95e-4)" "unprognostic (7.02e-3)" "unprognostic (6.02e-3)" "validated prognostic unfavorable (4.27e-4)" "validated prognostic unfavorable (5.50e-4)" "unprognostic (1.72e-1)" "unprognostic (5.75e-3)" "unprognostic (1.34e-1)" "unprognostic (1.37e-2)" "unprognostic (6.22e-2)" "unprognostic (4.27e-2)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (1.95e-1)" "unprognostic (2.58e-1)" "unprognostic (3.24e-2)" "unprognostic (3.30e-1)" "unprognostic (1.73e-2)" "unprognostic (1.80e-1)" "unprognostic (2.78e-1)" "unprognostic (2.50e-2)" VANGL1 STB2 ENSG00000173218 "VANGL planar cell polarity protein 1" Q8TAA9 1 115641970-115698224 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in many" "endothelial cell: 29.9;ependymal cell: 28.1;thalamic excitatory: 32.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.3;NK-cells: 6.2;T-cells: 3.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Mitotic cells (Skin), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025235, CAB076375" Approved Approved "Plasma membrane" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 12: Squamous epithelial cells - Keratinization" 17 "Plasma membrane" "CAB076375: AB_2665604, HPA025235: AB_1858718" "unprognostic (3.27e-1)" "unprognostic (6.69e-3)" "unprognostic (1.09e-1)" "unprognostic (2.60e-3)" "unprognostic (3.03e-3)" "unprognostic (1.91e-2)" "unprognostic (4.35e-2)" "unprognostic (3.99e-2)" "unprognostic (8.00e-2)" "unprognostic (3.69e-2)" "potential prognostic favorable (4.47e-7)" "unprognostic (1.01e-3)" "unprognostic (8.79e-2)" "unprognostic (2.85e-3)" "potential prognostic unfavorable (2.17e-4)" "validated prognostic unfavorable (4.66e-4)" "validated prognostic unfavorable (2.33e-4)" "unprognostic (1.69e-1)" "unprognostic (3.96e-1)" "unprognostic (3.08e-2)" "unprognostic (5.94e-2)" "unprognostic (1.09e-3)" "unprognostic (1.42e-1)" "unprognostic (4.98e-2)" "unprognostic (4.08e-3)" "unprognostic (1.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.34e-1)" "unprognostic (1.81e-1)" "unprognostic (4.52e-2)" "unprognostic (2.64e-1)" VTI1A "MVti1, Vti1-rp2" ENSG00000151532 "Vesicle transport through interaction with t-SNAREs 1A" Q96AJ9 10 112446998-112818744 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 128.2;Excitatory neurons: 236.5;Inhibitory neurons: 191.3;Late spermatids: 100.0;Microglial cells: 187.0;Oligodendrocyte precursor cells: 161.8;Oligodendrocytes: 203.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054108 Supported Approved "Golgi apparatus,Vesicles" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 51: Oligodendrocytes - Unknown function" 38 "Golgi apparatus, Vesicles" "HPA054108: AB_2682382" "unprognostic (5.89e-2)" "unprognostic (4.79e-2)" "unprognostic (1.30e-2)" "unprognostic (5.77e-2)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (2.80e-1)" "unprognostic (2.12e-3)" "unprognostic (2.55e-1)" "unprognostic (1.50e-3)" "potential prognostic favorable (2.35e-5)" "unprognostic (4.91e-2)" "unprognostic (9.10e-2)" "unprognostic (1.69e-3)" "unprognostic (1.83e-1)" "unprognostic (1.25e-1)" "unprognostic (1.44e-2)" "unprognostic (7.15e-2)" "unprognostic (1.32e-1)" "unprognostic (4.81e-3)" "unprognostic (8.62e-3)" "unprognostic (9.52e-2)" "potential prognostic unfavorable (4.44e-4)" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (3.23e-2)" "unprognostic (3.15e-1)" "unprognostic (4.05e-3)" "unprognostic (3.30e-2)" "unprognostic (1.16e-2)" "unprognostic (3.73e-2)" WNT2 "INT1L1, IRP" ENSG00000105989 "Wnt family member 2" P09544 7 117275451-117323152 "Cancer-related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 38.6" "Cell type enhanced" "Detected in some" "Early spermatids: 31.6;Endometrial stromal cells: 34.6;Fibroblasts: 12.0;Late spermatids: 17.5;Mesothelial cells: 9.9;Smooth muscle cells: 41.8;Spermatocytes: 11.0" "Group enriched" "Detected in some" 4 "hippocampal CA4: 5.7;thalamic excitatory: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.7" "Adipose subcutaneous - Adipose progenitor cells, Liver - Sinusoid Endothelial cells, Testis - Early spermatids" "Region enhanced" "Detected in many" "basal ganglia: 12.6" "Low region specificity" "Detected in many" HPA020920 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 7 Vesicles "HPA020920: AB_1858850" "unprognostic (8.88e-2)" "unprognostic (3.70e-1)" "unprognostic (1.63e-1)" "unprognostic (3.97e-2)" "unprognostic (4.42e-1)" "unprognostic (5.20e-3)" "unprognostic (1.29e-3)" "unprognostic (3.34e-1)" "unprognostic (1.61e-1)" "unprognostic (1.64e-1)" "unprognostic (2.78e-2)" "unprognostic (5.12e-1)" "unprognostic (2.25e-2)" "unprognostic (6.08e-3)" "unprognostic (4.25e-3)" "unprognostic (3.11e-1)" "unprognostic (3.56e-2)" "unprognostic (2.51e-2)" "unprognostic (1.07e-1)" WNT3 "INT4, MGC131950, MGC138321, MGC138323" ENSG00000108379 "Wnt family member 3" P56703 17 46762506-46833154 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 12.0;skin 1: 26.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 26.2;Early spermatids: 12.3;Late spermatids: 68.9;Suprabasal keratinocytes: 13.6" "Cell type enhanced" "Detected in many" "bergmann glia: 57.0;thalamic excitatory: 44.7" "Cancer enriched" "Detected in many" 6 "Testicular Germ Cell Tumor (TCGA): 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049893 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 11: Late spermatids - Unknown function" 2 Vesicles "HPA049893: " "unprognostic (2.87e-2)" "unprognostic (1.01e-1)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (7.56e-4)" "unprognostic (2.83e-2)" "unprognostic (4.92e-1)" "unprognostic (3.81e-2)" "unprognostic (6.28e-2)" "unprognostic (7.58e-2)" "unprognostic (4.32e-2)" "unprognostic (4.49e-2)" "unprognostic (3.19e-1)" "unprognostic (1.65e-1)" "unprognostic (1.32e-1)" "unprognostic (2.01e-1)" "unprognostic (4.37e-3)" "unprognostic (1.84e-1)" "unprognostic (5.46e-2)" "unprognostic (4.93e-1)" "unprognostic (2.64e-2)" WNT9B "WNT14B, WNT15" ENSG00000158955 "Wnt family member 9B" O14905 17 46833201-46886730 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 13.5;seminal vesicle: 9.4" "Group enriched" "Detected in some" 6 "Basal prostatic cells: 4.4;Collecting duct cells: 9.7" "Group enriched" "Detected in many" 4 "astrocyte: 6.6;bergmann glia: 12.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "testis cancer: 6.8" "Region enriched" "Detected in single" 7 "thalamus: 5.8" "Low region specificity" "Detected in all" "HPA058361, HPA059572" Approved Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 1 Vesicles "HPA058361: AB_2683691, HPA059572: AB_2684067" XKR4 KIAA1889 ENSG00000206579 "XK related 4" Q5GH76 8 55102028-55542054 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;intestine: 1.7" "Group enriched" "Detected in some" 6 "Excitatory neurons: 295.6;Inhibitory neurons: 977.1;Oligodendrocyte precursor cells: 676.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.8" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Schwann cells, Colon - Enteric glia cells, Minor Salivary Gland - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025072, HPA028083" Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" Vesicles "Nucleoli, Golgi apparatus" "HPA025072: AB_1858886, HPA028083: AB_10601025" "unprognostic (3.20e-3)" "unprognostic (4.66e-2)" ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713576-97739862 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.7;lymphoid tissue: 77.8" "Group enriched" "Detected in some" 7 "NK-cells: 140.6;T-cells: 97.5" "Cell type enriched" "Detected in some" 18 "leukocyte: 123.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 41 "gdT-cell: 137.8;MAIT T-cell: 93.5;memory CD4 T-cell: 71.8;memory CD8 T-cell: 108.1;naive CD4 T-cell: 50.8;naive CD8 T-cell: 80.2;NK-cell: 112.8;T-reg: 80.4" "Group enriched" "Detected in many" 56 "NK-cells: 112.8;T-cells: 137.8" "Group enriched" "Detected in some" 4 "Leukemia: 39.6;lymphoma: 10.7;Rhabdoid: 13.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002625, HPA003134" Enhanced NA NA 3000 "Cluster 1: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 31 "CAB002625: , HPA003134: AB_1080629" "unprognostic (1.19e-1)" "unprognostic (4.51e-3)" "unprognostic (2.92e-2)" "potential prognostic favorable (1.96e-4)" "unprognostic (4.23e-2)" "unprognostic (7.47e-2)" "unprognostic (9.07e-2)" "potential prognostic favorable (2.33e-5)" "unprognostic (4.29e-2)" "unprognostic (1.01e-2)" "unprognostic (6.20e-2)" "unprognostic (1.25e-1)" "unprognostic (4.78e-3)" "potential prognostic favorable (1.27e-4)" "unprognostic (3.34e-3)" "unprognostic (1.08e-1)" "unprognostic (2.62e-1)" "unprognostic (1.01e-1)" "unprognostic (4.07e-2)" "unprognostic (1.30e-2)" "unprognostic (1.89e-2)" "unprognostic (1.74e-2)" "unprognostic (1.92e-1)" "unprognostic (3.91e-2)" "unprognostic (6.02e-3)" "unprognostic (7.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.05e-1)" "unprognostic (1.95e-1)" "unprognostic (3.12e-1)" ZBTB7C "ZBTB36, ZNF857C" ENSG00000184828 "Zinc finger and BTB domain containing 7C" A1YPR0 18 48026672-48410752 "Predicted intracellular proteins, Transcription factors" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 68.7;Distal enterocytes: 51.7;Squamous epithelial cells: 98.7;Suprabasal keratinocytes: 66.4" "Cell type enhanced" "Detected in all" "ependymal cell: 354.3;vascular associated smooth muscle cell: 369.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 17 "cervical cancer: 137.2" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 4 "potential prognostic favorable (2.52e-5)" "unprognostic (1.20e-1)" "unprognostic (6.48e-2)" "unprognostic (4.65e-2)" "unprognostic (1.10e-3)" "unprognostic (1.09e-1)" "unprognostic (1.62e-1)" "unprognostic (1.33e-1)" "unprognostic (7.00e-3)" "unprognostic (7.36e-3)" "unprognostic (6.57e-2)" "unprognostic (1.80e-2)" "unprognostic (6.87e-2)" "unprognostic (1.75e-3)" "unprognostic (2.21e-2)" "unprognostic (1.61e-2)" "unprognostic (2.79e-1)" "unprognostic (9.37e-2)" "unprognostic (1.44e-2)" "potential prognostic favorable (4.23e-6)" "unprognostic (2.03e-1)" "unprognostic (8.18e-2)" "unprognostic (1.76e-3)" "unprognostic (5.79e-2)" "unprognostic (1.37e-1)" "unprognostic (1.05e-2)" "unprognostic (5.73e-2)" "unprognostic (2.38e-2)" ZDHHC22 C14orf59 ENSG00000177108 "Zinc finger DHHC-type palmitoyltransferase 22" Q8N966 14 77131270-77142734 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 36.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.2;Excitatory neurons: 8.5;Horizontal cells: 12.0;Inhibitory neurons: 12.8;Late spermatids: 4.9;Oligodendrocyte precursor cells: 23.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 37 "Glioblastoma Multiforme (TCGA): 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 8.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049471, HPA072213" Enhanced "Plasma membrane" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 69: Neurons - Neuronal signaling" 16 "Plasma membrane" "HPA049471: AB_2732553, HPA072213: AB_2686496" "unprognostic (3.07e-1)" "unprognostic (5.99e-2)" "potential prognostic favorable (9.77e-5)" ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type palmitoyltransferase 5" Q9C0B5 11 57667747-57701182 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity, Lipid transport, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 8 "Nucleoplasm, Plasma membrane" "HPA014670: AB_2257442" "unprognostic (3.98e-1)" "unprognostic (3.93e-2)" "unprognostic (1.29e-1)" "unprognostic (3.02e-3)" "unprognostic (7.02e-2)" "unprognostic (1.10e-2)" "unprognostic (9.67e-2)" "unprognostic (4.84e-2)" "unprognostic (2.79e-2)" "unprognostic (3.32e-3)" "potential prognostic favorable (2.64e-7)" "unprognostic (4.09e-3)" "unprognostic (4.76e-1)" "unprognostic (1.05e-1)" "unprognostic (2.07e-1)" "unprognostic (9.97e-3)" "potential prognostic unfavorable (2.65e-4)" "unprognostic (2.19e-1)" "unprognostic (2.57e-1)" "unprognostic (4.95e-2)" "unprognostic (7.66e-2)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (8.08e-2)" "unprognostic (9.84e-2)" "unprognostic (2.03e-2)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (2.17e-1)" "unprognostic (2.63e-1)" "unprognostic (8.02e-2)" "unprognostic (3.35e-1)" ZNF175 OTK18 ENSG00000105497 "Zinc finger protein 175" Q9Y473 19 51571283-51592510 "Predicted intracellular proteins, Transcription factors" "Antiviral defense, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 16.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002717, HPA074615" Uncertain Supported Nucleoli,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Cytotrophoblasts - Mitochondria" 4 Nucleoli Cytosol "HPA002717: AB_1080681, HPA074615: " "unprognostic (3.61e-3)" "unprognostic (7.50e-2)" "unprognostic (3.33e-3)" "unprognostic (1.58e-3)" "unprognostic (3.33e-1)" "unprognostic (1.91e-3)" "unprognostic (2.71e-1)" "unprognostic (9.15e-2)" "unprognostic (5.39e-3)" "unprognostic (4.77e-2)" "validated prognostic favorable (4.93e-5)" "validated prognostic favorable (5.29e-4)" "unprognostic (4.61e-2)" "unprognostic (1.31e-2)" "unprognostic (1.98e-3)" "unprognostic (1.75e-1)" "unprognostic (5.04e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-2)" "unprognostic (4.89e-2)" "unprognostic (3.02e-2)" "unprognostic (5.03e-2)" "unprognostic (2.44e-2)" "unprognostic (7.42e-2)" "unprognostic (6.27e-2)" "unprognostic (1.41e-2)" "unprognostic (1.25e-1)" "unprognostic (3.14e-1)" "unprognostic (2.32e-2)" "unprognostic (1.55e-1)" ZNF383 "FLJ35863, Zfp383" ENSG00000188283 "Zinc finger protein 383" Q8NA42 19 37217926-37248740 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063945 Approved Supported "Nucleoplasm,Nuclear membrane" No No "Cluster 24: Non-specific - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" 5 "Nucleoplasm, Nuclear membrane" "HPA063945: AB_2685158" "potential prognostic favorable (2.13e-4)" "unprognostic (6.68e-2)" "unprognostic (9.11e-2)" "unprognostic (3.03e-2)" "unprognostic (2.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.23e-2)" "unprognostic (4.56e-2)" "unprognostic (3.41e-2)" "unprognostic (2.04e-2)" "unprognostic (1.06e-3)" "potential prognostic favorable (5.98e-4)" "unprognostic (5.29e-3)" "unprognostic (5.54e-2)" "unprognostic (1.56e-1)" "unprognostic (3.05e-2)" "unprognostic (3.67e-2)" "unprognostic (1.77e-1)" "unprognostic (5.16e-2)" "unprognostic (1.18e-2)" "unprognostic (7.91e-2)" "unprognostic (7.04e-2)" "unprognostic (7.16e-3)" "unprognostic (2.52e-1)" "potential prognostic favorable (7.24e-5)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (5.89e-4)" "unprognostic (1.29e-1)" "unprognostic (4.07e-2)" "unprognostic (5.13e-3)" "unprognostic (1.16e-1)" ZNF423 "Ebfaz, hOAZ, JBTS19, KIAA0760, NPHP14, OAZ, Zfp104" ENSG00000102935 "Zinc finger protein 423" Q2M1K9 16 49487524-49857919 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 26.5" "Cell type enhanced" "Detected in many" "Astrocytes: 71.5;Late spermatids: 111.5;Leydig cells: 27.3;Microglial cells: 51.0;Oligodendrocyte precursor cells: 36.3;Peritubular cells: 49.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 200.3;endothelial cell: 228.5" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 15.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.7;testis cancer: 16.2" "Adrenal gland - Fibroblasts, Colon - Fibroblasts, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015258, HPA065820" Enhanced Nucleoplasm NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" 12 Nucleoplasm "HPA015258: , HPA065820: AB_2685563" "unprognostic (3.88e-2)" "unprognostic (3.22e-1)" "unprognostic (2.22e-1)" "unprognostic (3.02e-2)" "unprognostic (5.42e-2)" "unprognostic (3.61e-2)" "unprognostic (2.23e-1)" "unprognostic (5.42e-3)" "unprognostic (2.12e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-3)" "potential prognostic favorable (9.59e-4)" "unprognostic (4.13e-2)" "unprognostic (2.87e-2)" "unprognostic (2.10e-2)" "unprognostic (3.16e-3)" "unprognostic (2.01e-1)" "unprognostic (1.78e-1)" "unprognostic (9.14e-2)" "unprognostic (6.69e-2)" "unprognostic (2.88e-1)" "unprognostic (2.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.68e-1)" "unprognostic (9.55e-2)" "unprognostic (1.19e-2)" "unprognostic (1.65e-1)" "unprognostic (6.88e-2)" "unprognostic (4.70e-2)" ZNF467 "EZI, Zfp467" ENSG00000181444 "Zinc finger protein 467" Q7Z7K2 7 149764182-149773588 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 53.1;Distal tubular cells: 33.8;Hofbauer cells: 39.1;Kupffer cells: 41.7;Lymphatic endothelial cells: 39.8;Muller glia cells: 67.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 48.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 48.9" "Cancer enhanced" "Detected in many" "Rhabdoid: 17.8" "Spleen - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042907 Uncertain Approved Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 Mitochondria "HPA042907: AB_10966965" "unprognostic (1.93e-1)" "unprognostic (3.73e-1)" "unprognostic (5.56e-2)" "unprognostic (1.08e-1)" "unprognostic (1.64e-2)" "unprognostic (9.58e-2)" "unprognostic (6.96e-2)" "unprognostic (6.98e-2)" "unprognostic (1.99e-1)" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (8.93e-2)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (2.03e-1)" "unprognostic (1.38e-1)" "unprognostic (2.96e-1)" "unprognostic (4.96e-2)" "unprognostic (1.25e-2)" "unprognostic (1.45e-1)" "unprognostic (3.33e-2)" "unprognostic (3.10e-3)" "unprognostic (1.99e-3)" "unprognostic (2.07e-1)" "unprognostic (8.06e-3)" "unprognostic (3.18e-1)" "unprognostic (9.82e-2)" "unprognostic (4.14e-2)" "unprognostic (1.20e-1)" "unprognostic (1.35e-1)" "unprognostic (2.33e-2)" ZNF513 "FLJ32203, RP58, Zfp513" ENSG00000163795 "Zinc finger protein 513" Q8N8E2 2 27377235-27380790 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" DNA-binding "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 41.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051493 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 13: Spermatids - Transcription" 3 "HPA051493: AB_2681505" "unprognostic (2.42e-2)" "unprognostic (3.63e-1)" "unprognostic (4.57e-3)" "unprognostic (3.39e-3)" "unprognostic (9.85e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-1)" "unprognostic (5.85e-2)" "unprognostic (4.61e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (6.83e-2)" "unprognostic (4.07e-3)" "potential prognostic unfavorable (2.44e-5)" "unprognostic (1.54e-1)" "unprognostic (1.41e-2)" "unprognostic (1.09e-1)" "unprognostic (7.05e-2)" "unprognostic (6.52e-2)" "unprognostic (9.98e-2)" "unprognostic (1.11e-3)" "unprognostic (4.18e-2)" "unprognostic (6.99e-2)" "unprognostic (1.30e-1)" "unprognostic (2.82e-1)" "unprognostic (1.38e-1)" "unprognostic (4.99e-2)" "unprognostic (2.18e-1)" "unprognostic (1.75e-1)" "unprognostic (8.14e-2)" "unprognostic (1.43e-1)" ZNF516 "HsT287, KIAA0222" ENSG00000101493 "Zinc finger protein 516" Q92618 18 76357682-76495242 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 71.2;Endometrial stromal cells: 70.3;Langerhans cells: 79.6;Oligodendrocyte precursor cells: 69.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 10.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 10.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015792 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 9: Endometrial stromal cells - Transcription" 24 Nucleoplasm Cytosol "HPA015792: AB_1859314" "unprognostic (1.31e-3)" "unprognostic (2.19e-1)" "unprognostic (1.71e-1)" "unprognostic (2.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.61e-1)" "unprognostic (4.10e-1)" "unprognostic (5.54e-3)" "unprognostic (2.80e-1)" "unprognostic (2.66e-1)" "validated prognostic favorable (3.64e-6)" "validated prognostic favorable (9.15e-4)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (4.07e-4)" "unprognostic (8.23e-2)" "unprognostic (1.07e-2)" "unprognostic (2.26e-1)" "unprognostic (1.43e-1)" "unprognostic (6.38e-2)" "unprognostic (8.61e-2)" "unprognostic (2.35e-1)" "unprognostic (6.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.32e-1)" "unprognostic (6.06e-2)" "unprognostic (5.34e-3)" "unprognostic (1.91e-1)" "unprognostic (7.44e-2)" "unprognostic (1.32e-1)" "unprognostic (2.51e-2)" "unprognostic (7.62e-2)" ZNF629 "KIAA0326, ZNF65" ENSG00000102870 "Zinc finger protein 629" Q9UEG4 16 30778456-30787205 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019550, HPA056051" Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 68: Cardiomyocytes - Muscle contraction" 29 Nucleoplasm "Golgi apparatus" "HPA019550: AB_1859386, HPA056051: AB_2683020" "unprognostic (1.20e-2)" "unprognostic (7.75e-2)" "unprognostic (2.00e-2)" "unprognostic (5.13e-2)" "unprognostic (2.17e-1)" "unprognostic (2.87e-1)" "unprognostic (3.30e-1)" "unprognostic (1.38e-3)" "unprognostic (2.44e-2)" "unprognostic (1.40e-1)" "potential prognostic favorable (5.31e-5)" "unprognostic (2.67e-2)" "unprognostic (1.69e-3)" "unprognostic (2.78e-3)" "unprognostic (1.08e-1)" "unprognostic (8.55e-2)" "unprognostic (2.56e-1)" "unprognostic (3.32e-2)" "unprognostic (3.68e-3)" "unprognostic (1.72e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-2)" "unprognostic (2.44e-1)" "unprognostic (1.84e-1)" "unprognostic (2.11e-3)" "unprognostic (3.59e-1)" "unprognostic (1.59e-1)" "unprognostic (1.21e-1)" "unprognostic (2.35e-1)" "unprognostic (1.66e-3)" "unprognostic (1.05e-2)" ZWINT "KNTC2AP, SIP30, Zwint1" ENSG00000122952 "ZW10 interacting kinetochore protein" O95229 10 56357227-56361273 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.1;lymphoid tissue: 42.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.6;Erythroid cells: 123.9;Extravillous trophoblasts: 110.5;Late spermatids: 208.2;Oocytes: 86.8;Spermatocytes: 125.4;Spermatogonia: 87.2;Undifferentiated cells: 73.0" "Cell type enhanced" "Detected in many" "hippocampal CA4: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 17.0" "Lineage enriched" "Detected in many" 5 "T-cells: 17.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA005757, HPA022264" Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cell proliferation" 58 "Nucleoplasm, Nuclear bodies" Cytosol "HPA005757: AB_10600224, HPA022264: AB_10600995" "unprognostic (2.15e-2)" "unprognostic (1.13e-2)" "unprognostic (3.07e-2)" "unprognostic (9.00e-3)" "unprognostic (5.55e-2)" "unprognostic (2.02e-1)" "unprognostic (1.59e-1)" "unprognostic (1.78e-2)" "unprognostic (1.76e-1)" "unprognostic (1.72e-3)" "potential prognostic favorable (2.21e-4)" "unprognostic (6.02e-2)" "unprognostic (2.94e-3)" "validated prognostic unfavorable (4.93e-9)" "validated prognostic unfavorable (2.02e-5)" "validated prognostic unfavorable (7.09e-5)" "validated prognostic unfavorable (5.54e-4)" "potential prognostic favorable (7.25e-4)" "unprognostic (6.48e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (1.54e-3)" "unprognostic (9.82e-2)" "unprognostic (3.25e-2)" "unprognostic (1.63e-1)" "unprognostic (1.49e-1)" "unprognostic (6.13e-2)" "unprognostic (4.24e-2)" "unprognostic (2.17e-1)" "unprognostic (3.59e-2)" "unprognostic (1.11e-1)"