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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:116.9 nTPM
HPA Brain:75.4 nTPM
GTEx:116.9 nTPM
FANTOM5:17.6 Scaled Tags Per Million
Pig:30.0 nTPM
Mouse:32.8 nTPM
Allen mouse:1.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

75.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 66.8
2586 Male, age 75, left hemisphere 103.1
2828 Female, age 72, unknown 77.4
2219 Male, age 76, both hemispheres 69.3
2019 Male, age 18, unknown 68.7
1827 Male, age 72, unknown 68.1
1870 Female, age 42, unknown 58.3
2666 Male, age 74, left hemisphere 57.7
1833 Male, age 53, unknown 56.7
2411 Female, age 72, unknown 56.6
1830 Male, age 51, unknown 51.9
Dorsal raphe nucleus
nTPM: 63.7
2298 Female, age 72, unknown 71.4
2047 Male, age 72, unknown 69.4
2750 Male, age 76, both hemispheres 64.4
1828 Male, age 53, unknown 57.2
2016 Female, age 72, unknown 56.2
Inferior colliculus
nTPM: 53.8
2097 Female, age 72, unknown 60.7
1890 Male, age 53, unknown 56.8
1848 Female, age 42, unknown 53.2
2849 Male, age 72, unknown 44.5
Median raphe nucleus
nTPM: 64.6
2220 Male, age 76, midline 64.6
Periaquaductal grey, anterior
nTPM: 75.4
1795 Male, age 51, unknown 80.6
2502 Female, age 75, unknown 79.3
1947 Male, age 18, unknown 66.2
Periaquaductal grey, dorsal
nTPM: 57.0
1840 Male, age 53, unknown 61.7
2464 Female, age 72, unknown 58.1
1831 Male, age 72, unknown 55.5
2850 Male, age 76, both hemispheres 52.7
Periaquaductal grey, lateral
nTPM: 56.7
2272 Male, age 74, both hemispheres 62.2
2053 Male, age 18, unknown 57.0
2140 Male, age 76, both hemispheres 51.1
Pretectal area
nTPM: 67.5
1816 Male, age 51, unknown 90.7
2007 Male, age 72, unknown 80.4
1944 Female, age 72, unknown 79.5
1817 Female, age 42, unknown 73.7
1815 Male, age 53, unknown 72.4
2273 Male, age 74, both hemispheres 65.0
2667 Female, age 75, unknown 62.4
2407 Male, age 75, both hemispheres 60.9
2224 Female, age 72, unknown 55.3
2825 Male, age 18, unknown 54.3
2316 Male, age 76, right hemisphere 48.0
Red nucleus
nTPM: 64.6
2588 Male, age 74, left hemisphere 71.1
1904 Male, age 53, unknown 69.1
2785 Male, age 18, unknown 68.7
2769 Male, age 72, unknown 68.5
2503 Female, age 72, unknown 65.1
2725 Female, age 75, unknown 64.7
1865 Male, age 51, unknown 64.6
2227 Male, age 72, unknown 64.6
2584 Male, age 75, left hemisphere 61.5
1954 Female, age 42, unknown 61.2
1821 Female, age 72, unknown 60.3
2823 Male, age 76, right hemisphere 56.2
Substantia nigra
nTPM: 75.0
1916 Female, age 42, unknown 101.8
1851 Male, age 51, unknown 86.2
1889 Female, age 72, unknown 77.4
2665 Male, age 74, both hemispheres 75.7
2699 Male, age 18, unknown 72.1
1941 Male, age 53, unknown 71.0
2583 Male, age 75, right hemisphere 70.7
2409 Female, age 72, unknown 69.4
2590 Female, age 75, unknown 65.8
2241 Male, age 72, unknown 60.3
Superior colliculus
nTPM: 69.4
2261 Male, age 18, unknown 86.3
2087 Female, age 72, unknown 83.9
2664 Male, age 75, both hemispheres 82.4
1796 Male, age 53, unknown 78.0
2668 Female, age 75, unknown 77.1
1995 Male, age 72, unknown 70.3
1913 Female, age 42, unknown 63.5
2587 Male, age 74, left hemisphere 56.3
1839 Male, age 51, unknown 50.4
1895 Male, age 76, right hemisphere 46.2
Ventral tegmental area
nTPM: 69.6
1915 Female, age 42, unknown 76.5
2410 Female, age 72, unknown 73.0
2218 Male, age 76, both hemispheres 70.0
1942 Male, age 51, unknown 69.1
2223 Female, age 72, unknown 68.6
2021 Male, age 53, unknown 60.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

116.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 116.9
Samples: 139

Max nTPM: 253.6
Min nTPM: 43.7
Std nTPM: 33.4
Median nTPM: 112.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 253.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 197.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 189.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 188.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 182.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 179.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 176.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 175.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 174.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 173.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 171.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 170.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 165.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 160.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 160.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 159.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 157.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 154.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 154.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 153.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 152.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 150.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 147.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 146.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 143.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 143.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 143.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 142.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 141.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 140.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 140.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 139.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 139.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 137.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 135.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 135.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 135.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 134.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 134.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 133.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 131.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 131.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 131.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 130.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 129.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 128.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 128.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 127.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 125.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 125.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 125.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 125.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 124.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 124.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 122.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 121.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 120.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 120.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 119.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 118.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 118.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 118.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 117.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 117.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 117.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 117.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 114.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 114.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 113.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 112.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 112.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 112.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 112.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 111.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 110.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 110.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 109.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 109.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 108.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 107.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 106.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 106.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 106.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 105.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 105.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 105.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 103.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 101.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 101.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 101.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 100.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 99.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 98.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 98.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 98.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 98.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 98.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 97.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 96.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 96.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 95.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 95.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 94.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 93.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 93.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 93.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 92.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 92.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 91.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 91.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 90.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 90.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 90.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 89.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 89.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 88.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 88.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 87.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 87.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 87.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 87.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 84.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 81.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 79.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 76.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 75.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 74.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 72.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 69.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 69.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 67.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 66.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 65.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 63.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 58.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 58.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 57.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 55.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 43.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

17.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 17.6
FF:10158-103A5 76 years, female 17.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

30.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 29.2
Samples: 4

Max nTPM: 34.9
Min nTPM: 23.1
Sample A Female 34.9
Sample B Female 28.2
Sample C Male 30.6
Sample D Male 23.1
Midbrain
nTPM: 30.0
Samples: 4

Max nTPM: 39.7
Min nTPM: 23.7
Sample A Female 39.7
Sample B Female 28.1
Sample C Male 28.5
Sample D Male 23.7
Periaqueductal gray
nTPM: 24.7
Samples: 3

Max nTPM: 29.2
Min nTPM: 21.4
Sample B Female 23.4
Sample C Male 29.2
Sample D Male 21.4
Superior colliculi
nTPM: 29.4
Samples: 4

Max nTPM: 34.0
Min nTPM: 24.9
Sample A Female 31.6
Sample B Female 34.0
Sample C Male 27.1
Sample D Male 24.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

32.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 32.8
Samples: 4

Max nTPM: 36.8
Min nTPM: 29.1
Sample A Male 36.8
Sample B Male 29.2
Sample C Female 29.1
Sample D Female 36.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.3
74881790 Antisense, RP_060315_04_D03, Mouse strain C57BL/6J (56 days, male) 2.3
69528052 Antisense, RP_050421_03_A05, Mouse strain C57BL/6J (56 days, male) 0.3

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