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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:42.0 nTPM
HPA Brain:104.1 nTPM
GTEx:42.0 nTPM
FANTOM5:11.4 Scaled Tags Per Million
Pig:35.1 nTPM
Mouse:35.2 nTPM
Allen mouse:0.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

104.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 60.3
2019 Male, age 18, unknown 107.6
2828 Female, age 72, unknown 83.8
2586 Male, age 75, left hemisphere 76.0
2666 Male, age 74, left hemisphere 65.6
2219 Male, age 76, both hemispheres 62.2
1827 Male, age 72, unknown 58.8
2411 Female, age 72, unknown 39.0
1870 Female, age 42, unknown 38.8
1833 Male, age 53, unknown 37.0
1830 Male, age 51, unknown 34.2
Dorsal raphe nucleus
nTPM: 36.9
2750 Male, age 76, both hemispheres 44.9
2298 Female, age 72, unknown 40.0
2047 Male, age 72, unknown 36.9
1828 Male, age 53, unknown 35.8
2016 Female, age 72, unknown 26.7
Inferior colliculus
nTPM: 43.4
1890 Male, age 53, unknown 50.5
2097 Female, age 72, unknown 47.2
1848 Female, age 42, unknown 42.3
2849 Male, age 72, unknown 33.6
Median raphe nucleus
nTPM: 46.0
2220 Male, age 76, midline 46.0
Periaquaductal grey, anterior
nTPM: 65.3
1795 Male, age 51, unknown 88.6
2502 Female, age 75, unknown 57.8
1947 Male, age 18, unknown 49.4
Periaquaductal grey, dorsal
nTPM: 43.1
1831 Male, age 72, unknown 57.2
1840 Male, age 53, unknown 39.3
2464 Female, age 72, unknown 38.1
2850 Male, age 76, both hemispheres 37.9
Periaquaductal grey, lateral
nTPM: 35.3
2053 Male, age 18, unknown 37.1
2140 Male, age 76, both hemispheres 37.1
2272 Male, age 74, both hemispheres 31.8
Pretectal area
nTPM: 104.1
1944 Female, age 72, unknown 205.8
1816 Male, age 51, unknown 195.0
2007 Male, age 72, unknown 176.4
1817 Female, age 42, unknown 174.3
1815 Male, age 53, unknown 143.1
2667 Female, age 75, unknown 72.2
2273 Male, age 74, both hemispheres 39.3
2407 Male, age 75, both hemispheres 38.8
2224 Female, age 72, unknown 35.7
2825 Male, age 18, unknown 34.5
2316 Male, age 76, right hemisphere 30.1
Red nucleus
nTPM: 49.7
2785 Male, age 18, unknown 106.6
2588 Male, age 74, left hemisphere 62.5
2725 Female, age 75, unknown 53.3
2584 Male, age 75, left hemisphere 50.8
2503 Female, age 72, unknown 44.9
2823 Male, age 76, right hemisphere 44.6
1954 Female, age 42, unknown 43.5
1821 Female, age 72, unknown 39.6
1865 Male, age 51, unknown 39.0
1904 Male, age 53, unknown 38.7
2769 Male, age 72, unknown 36.7
2227 Male, age 72, unknown 35.9
Substantia nigra
nTPM: 71.8
1889 Female, age 72, unknown 133.0
2665 Male, age 74, both hemispheres 106.9
1916 Female, age 42, unknown 88.5
1941 Male, age 53, unknown 85.3
1851 Male, age 51, unknown 67.8
2583 Male, age 75, right hemisphere 61.5
2590 Female, age 75, unknown 48.8
2409 Female, age 72, unknown 47.0
2241 Male, age 72, unknown 40.4
2699 Male, age 18, unknown 38.5
Superior colliculus
nTPM: 75.5
2087 Female, age 72, unknown 168.6
2668 Female, age 75, unknown 99.3
1913 Female, age 42, unknown 77.0
2261 Male, age 18, unknown 75.9
1995 Male, age 72, unknown 75.6
2664 Male, age 75, both hemispheres 66.2
1796 Male, age 53, unknown 66.0
1895 Male, age 76, right hemisphere 47.8
2587 Male, age 74, left hemisphere 39.3
1839 Male, age 51, unknown 38.8
Ventral tegmental area
nTPM: 48.9
2218 Male, age 76, both hemispheres 67.9
2410 Female, age 72, unknown 63.9
1915 Female, age 42, unknown 50.3
1942 Male, age 51, unknown 46.1
2021 Male, age 53, unknown 36.0
2223 Female, age 72, unknown 29.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

42.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 42.0
Samples: 139

Max nTPM: 116.7
Min nTPM: 9.7
Std nTPM: 21.8
Median nTPM: 37.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 116.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 100.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 98.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 95.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 88.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 84.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 83.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 83.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 83.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 80.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 78.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 78.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 75.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 74.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 71.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 68.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 67.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 67.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 66.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 66.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 66.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 65.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 65.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 64.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 63.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 63.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 62.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 60.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 59.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 58.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 58.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 58.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 57.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 57.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 54.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 53.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 52.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 52.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 51.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 50.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 49.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 49.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 49.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 48.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 48.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 47.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 47.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 46.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 46.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 45.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 45.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 45.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 45.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 44.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 44.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 44.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 44.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 43.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 43.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 43.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 43.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 42.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 41.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 41.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 41.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 39.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 38.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 38.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 38.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 37.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 37.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 37.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 36.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 36.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 36.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 36.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 35.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 35.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 35.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 34.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 34.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 33.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 33.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 32.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 32.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 32.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 31.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 31.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 31.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 30.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 30.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 30.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 30.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 29.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 28.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 27.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 26.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 26.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 26.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 26.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 25.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 25.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 25.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 24.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 23.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 23.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 23.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 23.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 22.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 22.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 22.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 22.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 21.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 21.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 21.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 21.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 20.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 20.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 20.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 18.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 18.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 18.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 18.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 17.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 16.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 16.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 16.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 16.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 15.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 15.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 15.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 14.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 13.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 12.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 12.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 11.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 10.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 10.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 9.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

11.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 11.4
FF:10158-103A5 76 years, female 11.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

35.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 19.7
Samples: 4

Max nTPM: 29.8
Min nTPM: 7.4
Sample A Female 29.8
Sample B Female 15.1
Sample C Male 26.5
Sample D Male 7.4
Midbrain
nTPM: 30.2
Samples: 4

Max nTPM: 67.8
Min nTPM: 8.6
Sample A Female 8.6
Sample B Female 19.6
Sample C Male 67.8
Sample D Male 24.9
Periaqueductal gray
nTPM: 18.0
Samples: 3

Max nTPM: 22.1
Min nTPM: 14.3
Sample B Female 17.6
Sample C Male 22.1
Sample D Male 14.3
Superior colliculi
nTPM: 35.1
Samples: 4

Max nTPM: 58.1
Min nTPM: 25.6
Sample A Female 26.6
Sample B Female 25.6
Sample C Male 58.1
Sample D Male 30.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

35.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 35.2
Samples: 4

Max nTPM: 36.8
Min nTPM: 33.4
Sample A Male 36.8
Sample B Male 33.4
Sample C Female 35.1
Sample D Female 35.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.3
68745251 Antisense, RP_050210_01_E10, Mouse strain C57BL/6J (56 days, male) 0.3

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