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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
516.3
nTPM
HPA:
516.3
nTPM
GTEx:
106.6
nTPM
FANTOM5:
656.3
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA001610
Cholangiocytes
Low
Hepatocytes
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
516.3
Female, age 60
Liver sample 21 nTPM: 234
Male, age 54
Liver sample 23 nTPM: 282.2
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 495.4
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 547.6
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 559.2
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 434.7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 591
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 575.9
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 635.8
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 807.1
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
106.6
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 106.6
Samples: 226
Max nTPM: 295.8
Min nTPM: 3.8
Std nTPM: 57.7
Median nTPM: 105.0
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
295.8
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
286.6
GTEX-18A7A-1526-SM-72D69
50-59 years, female
240.6
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
236.2
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
225.1
GTEX-14E7W-1526-SM-6871X
70-79 years, male
222.3
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
221.8
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
220.4
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
214.3
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
213.8
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
213.3
GTEX-14JG1-1626-SM-664NH
40-49 years, male
204.1
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
203.3
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
196.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
195.5
GTEX-R53T-0326-SM-48FEC
50-59 years, female
190.5
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
190.3
GTEX-18465-1626-SM-7LG6N
50-59 years, male
189.0
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
187.2
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
186.6
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
185.6
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
185.3
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
179.5
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
179.4
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
179.2
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
174.9
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
174.6
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
172.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
171.1
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
170.9
GTEX-13112-1426-SM-5EGH8
50-59 years, male
170.9
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
170.9
GTEX-144GL-1426-SM-79OMA
50-59 years, male
170.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
170.3
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
168.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
167.8
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
166.8
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
164.2
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
161.2
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
160.6
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
160.5
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
159.7
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
159.7
GTEX-1B932-1426-SM-793AN
40-49 years, female
156.6
GTEX-14PHX-0526-SM-664NW
50-59 years, male
156.3
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
155.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
154.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
153.0
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
152.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
151.2
GTEX-17F96-1226-SM-79OK2
70-79 years, male
151.0
GTEX-QESD-2026-SM-447BI
20-29 years, male
149.0
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
148.9
GTEX-17HHE-0126-SM-79398
50-59 years, male
146.7
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
146.5
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
145.3
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
144.0
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
143.7
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
143.7
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
143.2
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
143.0
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
142.1
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
142.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
139.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
139.3
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
138.9
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
138.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
136.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
135.4
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
134.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
133.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
133.8
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
133.7
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
133.6
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
133.5
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
131.0
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
129.7
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
129.7
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
129.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
127.1
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
127.1
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
126.8
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
126.6
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
126.4
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
125.8
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
125.0
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
124.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
124.4
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
123.2
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
121.9
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
121.8
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
121.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
120.1
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
120.0
GTEX-RN64-1826-SM-48FDV
50-59 years, male
119.8
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
119.3
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
118.3
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
118.1
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
118.0
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
116.3
GTEX-P78B-1326-SM-3P611
40-49 years, female
115.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
115.4
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
115.0
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
113.7
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
113.6
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
112.6
GTEX-RU72-1426-SM-46MUF
50-59 years, female
112.1
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
110.6
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
110.3
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
107.7
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
107.5
GTEX-18A66-2026-SM-7189C
60-69 years, male
106.6
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
105.3
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
104.6
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
103.1
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
102.6
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
101.9
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
101.3
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
101.1
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
100.1
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
96.8
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
96.0
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
95.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
94.2
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
93.6
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
93.4
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
93.2
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
92.0
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
92.0
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
91.6
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
91.0
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
90.5
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
90.4
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
90.1
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
89.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
89.6
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
89.4
GTEX-1B933-1226-SM-731DW
50-59 years, female
89.2
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
89.0
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
88.3
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
87.6
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
86.4
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
86.1
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
84.7
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
83.7
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
82.9
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
82.5
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
81.4
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
80.3
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
79.1
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
78.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
76.6
GTEX-S33H-1626-SM-4AD68
30-39 years, male
75.4
GTEX-X261-1726-SM-4PQYT
50-59 years, male
74.1
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
73.1
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
72.1
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
71.4
GTEX-13113-1326-SM-5GCOI
60-69 years, female
70.8
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
70.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
70.2
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
70.0
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
68.9
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
67.0
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
66.5
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
63.6
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
62.8
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
62.4
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
60.1
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
59.3
GTEX-REY6-1226-SM-48FDR
60-69 years, male
58.1
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
57.8
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
57.8
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
57.7
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
57.3
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
57.0
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
56.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
56.4
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
55.5
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
54.5
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
53.8
GTEX-QEL4-1226-SM-447A4
50-59 years, male
53.1
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
53.0
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
52.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
52.2
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
50.4
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
49.5
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
49.3
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
48.3
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
47.6
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
45.3
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
44.8
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
44.5
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
43.4
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
42.5
GTEX-Q734-0326-SM-48U15
40-49 years, female
41.4
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
40.5
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
40.1
GTEX-12696-0826-SM-5EGGE
60-69 years, male
39.5
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
36.1
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
35.7
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
34.6
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
34.3
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
33.5
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
32.9
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
29.3
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
28.9
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
27.7
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
26.0
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
24.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
23.0
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
21.0
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
20.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
18.3
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
14.8
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
14.7
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
13.8
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
11.5
GTEX-S32W-1926-SM-4AD63
50-59 years, female
10.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
9.7
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
9.2
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
8.6
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
8.2
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
6.9
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
6.1
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
4.5
GTEX-14XAO-0226-SM-68728
60-69 years, female
3.8
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
