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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:76.4 nTPM
HPA Brain:124.9 nTPM
GTEx:76.4 nTPM
FANTOM5:82.4 Scaled Tags Per Million
Pig:74.0 nTPM
Mouse:27.4 nTPM
Allen mouse:2.1 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

124.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 103.4
2586 Male, age 75, left hemisphere 127.4
1830 Male, age 51, unknown 125.4
2411 Female, age 72, unknown 123.3
1833 Male, age 53, unknown 120.6
2828 Female, age 72, unknown 105.1
2019 Male, age 18, unknown 103.2
1870 Female, age 42, unknown 100.0
2219 Male, age 76, both hemispheres 81.0
2666 Male, age 74, left hemisphere 75.1
1827 Male, age 72, unknown 73.0
Dorsal raphe nucleus
nTPM: 71.1
2750 Male, age 76, both hemispheres 110.6
2016 Female, age 72, unknown 78.2
1828 Male, age 53, unknown 71.0
2047 Male, age 72, unknown 51.7
2298 Female, age 72, unknown 43.9
Inferior colliculus
nTPM: 67.1
2849 Male, age 72, unknown 72.8
1890 Male, age 53, unknown 71.3
1848 Female, age 42, unknown 67.4
2097 Female, age 72, unknown 56.8
Median raphe nucleus
nTPM: 57.6
2220 Male, age 76, midline 57.6
Periaquaductal grey, anterior
nTPM: 75.5
2502 Female, age 75, unknown 103.4
1947 Male, age 18, unknown 65.5
1795 Male, age 51, unknown 57.5
Periaquaductal grey, dorsal
nTPM: 53.8
2464 Female, age 72, unknown 80.5
1831 Male, age 72, unknown 50.2
2850 Male, age 76, both hemispheres 43.0
1840 Male, age 53, unknown 41.4
Periaquaductal grey, lateral
nTPM: 62.2
2272 Male, age 74, both hemispheres 67.6
2053 Male, age 18, unknown 60.4
2140 Male, age 76, both hemispheres 58.7
Pretectal area
nTPM: 68.0
2316 Male, age 76, right hemisphere 104.4
2407 Male, age 75, both hemispheres 90.5
1815 Male, age 53, unknown 85.2
2825 Male, age 18, unknown 71.6
2007 Male, age 72, unknown 69.8
1817 Female, age 42, unknown 67.2
2667 Female, age 75, unknown 59.6
2224 Female, age 72, unknown 55.6
2273 Male, age 74, both hemispheres 53.1
1944 Female, age 72, unknown 45.8
1816 Male, age 51, unknown 45.3
Red nucleus
nTPM: 124.9
1904 Male, age 53, unknown 151.2
2769 Male, age 72, unknown 144.5
2227 Male, age 72, unknown 143.4
1865 Male, age 51, unknown 142.3
2785 Male, age 18, unknown 134.9
2503 Female, age 72, unknown 127.3
2823 Male, age 76, right hemisphere 126.2
2584 Male, age 75, left hemisphere 115.0
1821 Female, age 72, unknown 114.7
2588 Male, age 74, left hemisphere 107.8
1954 Female, age 42, unknown 105.5
2725 Female, age 75, unknown 86.2
Substantia nigra
nTPM: 76.9
2583 Male, age 75, right hemisphere 102.3
2699 Male, age 18, unknown 97.0
2590 Female, age 75, unknown 91.4
1851 Male, age 51, unknown 86.6
2409 Female, age 72, unknown 78.8
1889 Female, age 72, unknown 73.7
2665 Male, age 74, both hemispheres 65.6
1941 Male, age 53, unknown 59.0
1916 Female, age 42, unknown 58.5
2241 Male, age 72, unknown 55.7
Superior colliculus
nTPM: 90.4
1995 Male, age 72, unknown 138.7
1913 Female, age 42, unknown 128.2
1895 Male, age 76, right hemisphere 100.3
1839 Male, age 51, unknown 97.3
2587 Male, age 74, left hemisphere 84.8
2664 Male, age 75, both hemispheres 84.1
2668 Female, age 75, unknown 79.7
1796 Male, age 53, unknown 78.0
2261 Male, age 18, unknown 63.6
2087 Female, age 72, unknown 49.3
Ventral tegmental area
nTPM: 84.0
2223 Female, age 72, unknown 114.6
2410 Female, age 72, unknown 101.2
1942 Male, age 51, unknown 82.0
1915 Female, age 42, unknown 69.1
2218 Male, age 76, both hemispheres 68.8
2021 Male, age 53, unknown 68.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

76.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 76.4
Samples: 139

Max nTPM: 233.5
Min nTPM: 21.0
Std nTPM: 34.5
Median nTPM: 72.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 233.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 207.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 183.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 173.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 164.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 151.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 147.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 142.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 135.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 132.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 129.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 117.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 116.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 114.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 113.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 113.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 112.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 111.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 106.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 106.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 105.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 101.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 99.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 97.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 96.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 96.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 93.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 93.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 92.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 91.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 91.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 89.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 89.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 88.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 87.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 87.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 86.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 86.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 86.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 85.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 85.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 85.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 85.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 85.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 85.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 85.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 82.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 82.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 81.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 80.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 80.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 79.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 78.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 78.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 78.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 78.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 78.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 78.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 77.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 77.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 77.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 76.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 75.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 75.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 75.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 74.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 74.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 72.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 72.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 72.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 72.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 72.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 71.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 71.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 70.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 70.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 67.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 67.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 67.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 67.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 65.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 65.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 65.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 64.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 63.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 63.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 63.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 63.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 62.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 62.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 61.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 61.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 60.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 59.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 59.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 59.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 59.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 58.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 57.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 57.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 57.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 56.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 56.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 56.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 54.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 53.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 53.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 52.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 51.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 50.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 49.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 48.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 47.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 46.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 45.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 44.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 43.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 42.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 42.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 41.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 40.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 39.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 38.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 38.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 38.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 37.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 37.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 37.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 37.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 36.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 34.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 33.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 32.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 32.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 31.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 31.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 30.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 29.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 21.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

82.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 82.4
FF:10158-103A5 76 years, female 82.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

74.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 69.9
Samples: 4

Max nTPM: 94.7
Min nTPM: 49.3
Sample A Female 77.3
Sample B Female 49.3
Sample C Male 58.2
Sample D Male 94.7
Midbrain
nTPM: 74.0
Samples: 4

Max nTPM: 151.7
Min nTPM: 40.6
Sample A Female 151.7
Sample B Female 62.4
Sample C Male 40.6
Sample D Male 41.3
Periaqueductal gray
nTPM: 53.3
Samples: 3

Max nTPM: 60.7
Min nTPM: 46.3
Sample B Female 60.7
Sample C Male 46.3
Sample D Male 52.8
Superior colliculi
nTPM: 53.8
Samples: 4

Max nTPM: 68.8
Min nTPM: 30.0
Sample A Female 68.8
Sample B Female 30.0
Sample C Male 53.4
Sample D Male 62.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

27.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 27.4
Samples: 4

Max nTPM: 29.5
Min nTPM: 25.0
Sample A Male 29.5
Sample B Male 25.0
Sample C Female 25.6
Sample D Female 29.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.1
74988736 Antisense, RP_060315_04_B04, Mouse strain C57BL/6J (56 days, male) 2.6
70593371 Antisense, RP_050407_04_B08, Mouse strain C57BL/6J (56 days, male) 1.7

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