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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:72.4 nTPM
HPA Brain:156.9 nTPM
GTEx:72.4 nTPM
FANTOM5:136.0 Scaled Tags Per Million
Pig:96.4 nTPM
Mouse:100.9 nTPM
Allen mouse:0.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

156.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 132.4
2586 Male, age 75, left hemisphere 143.7
1827 Male, age 72, unknown 142.7
2411 Female, age 72, unknown 142.7
2666 Male, age 74, left hemisphere 141.8
2828 Female, age 72, unknown 134.8
2019 Male, age 18, unknown 131.7
1870 Female, age 42, unknown 127.6
1833 Male, age 53, unknown 123.6
2219 Male, age 76, both hemispheres 119.0
1830 Male, age 51, unknown 116.3
Dorsal raphe nucleus
nTPM: 137.5
2298 Female, age 72, unknown 146.7
2047 Male, age 72, unknown 144.7
2750 Male, age 76, both hemispheres 134.5
1828 Male, age 53, unknown 132.9
2016 Female, age 72, unknown 128.5
Inferior colliculus
nTPM: 122.4
2097 Female, age 72, unknown 130.7
1890 Male, age 53, unknown 123.1
1848 Female, age 42, unknown 121.5
2849 Male, age 72, unknown 114.2
Median raphe nucleus
nTPM: 131.2
2220 Male, age 76, midline 131.2
Periaquaductal grey, anterior
nTPM: 140.5
2502 Female, age 75, unknown 143.6
1947 Male, age 18, unknown 140.0
1795 Male, age 51, unknown 137.8
Periaquaductal grey, dorsal
nTPM: 125.2
1840 Male, age 53, unknown 135.4
2464 Female, age 72, unknown 122.7
1831 Male, age 72, unknown 122.2
2850 Male, age 76, both hemispheres 120.4
Periaquaductal grey, lateral
nTPM: 118.0
2053 Male, age 18, unknown 129.1
2272 Male, age 74, both hemispheres 115.4
2140 Male, age 76, both hemispheres 109.6
Pretectal area
nTPM: 139.1
1816 Male, age 51, unknown 169.0
1944 Female, age 72, unknown 156.0
1817 Female, age 42, unknown 152.1
2007 Male, age 72, unknown 147.3
1815 Male, age 53, unknown 146.3
2667 Female, age 75, unknown 146.1
2224 Female, age 72, unknown 128.9
2273 Male, age 74, both hemispheres 127.1
2407 Male, age 75, both hemispheres 124.8
2825 Male, age 18, unknown 124.5
2316 Male, age 76, right hemisphere 107.9
Red nucleus
nTPM: 125.2
1821 Female, age 72, unknown 151.5
2584 Male, age 75, left hemisphere 132.5
1904 Male, age 53, unknown 129.5
1954 Female, age 42, unknown 127.7
2588 Male, age 74, left hemisphere 125.8
2769 Male, age 72, unknown 124.9
2785 Male, age 18, unknown 121.5
2227 Male, age 72, unknown 120.5
2503 Female, age 72, unknown 119.2
2725 Female, age 75, unknown 118.1
1865 Male, age 51, unknown 116.9
2823 Male, age 76, right hemisphere 113.8
Substantia nigra
nTPM: 156.9
1916 Female, age 42, unknown 200.6
2241 Male, age 72, unknown 179.8
1851 Male, age 51, unknown 170.8
1889 Female, age 72, unknown 157.0
1941 Male, age 53, unknown 152.1
2665 Male, age 74, both hemispheres 150.4
2699 Male, age 18, unknown 143.6
2583 Male, age 75, right hemisphere 140.7
2590 Female, age 75, unknown 139.5
2409 Female, age 72, unknown 134.1
Superior colliculus
nTPM: 132.1
2087 Female, age 72, unknown 150.6
2261 Male, age 18, unknown 148.9
2668 Female, age 75, unknown 143.2
1796 Male, age 53, unknown 142.5
2664 Male, age 75, both hemispheres 139.8
2587 Male, age 74, left hemisphere 127.6
1839 Male, age 51, unknown 126.2
1895 Male, age 76, right hemisphere 119.5
1913 Female, age 42, unknown 116.9
1995 Male, age 72, unknown 105.9
Ventral tegmental area
nTPM: 146.8
1915 Female, age 42, unknown 166.3
2410 Female, age 72, unknown 162.1
2218 Male, age 76, both hemispheres 149.3
1942 Male, age 51, unknown 139.8
2223 Female, age 72, unknown 136.3
2021 Male, age 53, unknown 126.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

72.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 72.4
Samples: 139

Max nTPM: 107.9
Min nTPM: 48.8
Std nTPM: 11.1
Median nTPM: 71.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 107.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 103.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 101.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 98.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 95.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 94.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 94.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 93.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 91.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 91.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 91.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 90.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 90.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 89.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 89.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 89.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 86.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 85.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 84.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 83.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 82.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 82.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 81.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 81.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 81.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 81.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 80.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 80.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 80.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 80.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 79.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 78.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 78.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 78.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 78.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 78.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 78.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 78.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 77.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 77.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 77.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 77.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 77.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 77.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 76.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 76.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 76.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 75.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 75.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 75.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 75.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 75.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 74.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 74.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 74.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 73.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 73.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 73.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 73.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 73.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 72.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 72.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 72.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 72.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 71.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 71.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 71.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 71.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 71.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 71.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 71.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 70.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 70.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 70.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 70.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 70.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 69.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 69.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 69.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 69.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 69.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 69.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 68.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 68.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 68.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 68.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 68.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 68.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 67.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 67.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 67.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 67.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 66.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 66.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 66.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 66.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 66.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 66.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 66.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 65.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 65.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 65.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 65.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 65.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 64.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 64.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 64.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 64.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 63.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 63.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 63.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 63.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 63.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 63.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 63.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 62.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 62.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 62.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 62.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 61.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 61.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 60.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 60.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 60.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 59.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 59.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 59.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 58.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 58.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 57.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 57.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 56.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 56.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 55.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 54.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 52.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 51.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 48.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 48.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

136.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 136.0
FF:10158-103A5 76 years, female 136.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

96.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 86.7
Samples: 4

Max nTPM: 110.2
Min nTPM: 66.1
Sample A Female 110.2
Sample B Female 73.8
Sample C Male 96.8
Sample D Male 66.1
Midbrain
nTPM: 96.4
Samples: 4

Max nTPM: 117.8
Min nTPM: 77.8
Sample A Female 107.5
Sample B Female 77.8
Sample C Male 117.8
Sample D Male 82.3
Periaqueductal gray
nTPM: 71.8
Samples: 3

Max nTPM: 78.7
Min nTPM: 64.1
Sample B Female 72.7
Sample C Male 78.7
Sample D Male 64.1
Superior colliculi
nTPM: 89.4
Samples: 4

Max nTPM: 106.4
Min nTPM: 74.2
Sample A Female 93.8
Sample B Female 74.2
Sample C Male 106.4
Sample D Male 83.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

100.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 100.9
Samples: 4

Max nTPM: 107.5
Min nTPM: 92.3
Sample A Male 92.3
Sample B Male 102.6
Sample C Female 107.5
Sample D Female 101.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.8
112648612 Antisense, RP_110407_02_D01, Mouse strain C57BL/6J (56 days, male) 1.9
97 Antisense, RP_Baylor_103280, Mouse strain C57BL/6J (56 days, male) 0.4
96 Antisense, RP_Baylor_103280, Mouse strain C57BL/6J (56 days, male) 0.2
99 Sense, RPS_Baylor_37100, Mouse strain C57BL/6J (56 days, male) 0.0

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The Human Protein Atlas

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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