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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:164.2 nTPM
HPA Brain:229.1 nTPM
GTEx:164.2 nTPM
FANTOM5:439.0 Scaled Tags Per Million
Pig:232.5 nTPM
Mouse:125.7 nTPM
Allen mouse:12.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

229.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 186.5
2019 Male, age 18, unknown 217.9
2586 Male, age 75, left hemisphere 202.1
2411 Female, age 72, unknown 195.7
2666 Male, age 74, left hemisphere 190.6
1870 Female, age 42, unknown 189.1
1827 Male, age 72, unknown 188.6
1833 Male, age 53, unknown 180.4
1830 Male, age 51, unknown 176.9
2828 Female, age 72, unknown 168.9
2219 Male, age 76, both hemispheres 155.1
Dorsal raphe nucleus
nTPM: 192.0
2298 Female, age 72, unknown 206.9
1828 Male, age 53, unknown 190.3
2750 Male, age 76, both hemispheres 188.5
2016 Female, age 72, unknown 187.2
2047 Male, age 72, unknown 187.2
Inferior colliculus
nTPM: 177.3
1890 Male, age 53, unknown 190.4
2097 Female, age 72, unknown 185.6
1848 Female, age 42, unknown 172.9
2849 Male, age 72, unknown 160.1
Median raphe nucleus
nTPM: 182.3
2220 Male, age 76, midline 182.3
Periaquaductal grey, anterior
nTPM: 196.4
2502 Female, age 75, unknown 231.0
1947 Male, age 18, unknown 190.9
1795 Male, age 51, unknown 167.4
Periaquaductal grey, dorsal
nTPM: 170.7
1831 Male, age 72, unknown 180.7
1840 Male, age 53, unknown 175.2
2464 Female, age 72, unknown 170.0
2850 Male, age 76, both hemispheres 156.9
Periaquaductal grey, lateral
nTPM: 164.4
2272 Male, age 74, both hemispheres 173.9
2053 Male, age 18, unknown 171.8
2140 Male, age 76, both hemispheres 147.4
Pretectal area
nTPM: 187.5
1817 Female, age 42, unknown 220.6
1815 Male, age 53, unknown 214.2
2007 Male, age 72, unknown 213.9
1816 Male, age 51, unknown 212.7
1944 Female, age 72, unknown 206.4
2224 Female, age 72, unknown 184.9
2273 Male, age 74, both hemispheres 178.1
2407 Male, age 75, both hemispheres 170.6
2825 Male, age 18, unknown 160.6
2667 Female, age 75, unknown 160.4
2316 Male, age 76, right hemisphere 140.1
Red nucleus
nTPM: 198.4
1821 Female, age 72, unknown 242.0
1865 Male, age 51, unknown 211.8
2503 Female, age 72, unknown 207.6
2725 Female, age 75, unknown 207.3
2785 Male, age 18, unknown 200.6
2584 Male, age 75, left hemisphere 198.4
1904 Male, age 53, unknown 194.0
1954 Female, age 42, unknown 193.4
2588 Male, age 74, left hemisphere 188.2
2769 Male, age 72, unknown 181.4
2823 Male, age 76, right hemisphere 178.4
2227 Male, age 72, unknown 178.0
Substantia nigra
nTPM: 229.1
1916 Female, age 42, unknown 268.8
2409 Female, age 72, unknown 258.9
2241 Male, age 72, unknown 251.9
1851 Male, age 51, unknown 246.5
1941 Male, age 53, unknown 225.9
2699 Male, age 18, unknown 221.6
1889 Female, age 72, unknown 220.7
2590 Female, age 75, unknown 208.8
2665 Male, age 74, both hemispheres 208.1
2583 Male, age 75, right hemisphere 179.7
Superior colliculus
nTPM: 183.1
2587 Male, age 74, left hemisphere 216.3
2668 Female, age 75, unknown 185.3
2087 Female, age 72, unknown 184.8
1995 Male, age 72, unknown 182.5
2664 Male, age 75, both hemispheres 182.0
1913 Female, age 42, unknown 179.2
2261 Male, age 18, unknown 177.2
1839 Male, age 51, unknown 176.8
1895 Male, age 76, right hemisphere 174.5
1796 Male, age 53, unknown 172.4
Ventral tegmental area
nTPM: 197.0
2410 Female, age 72, unknown 223.0
1915 Female, age 42, unknown 212.3
2218 Male, age 76, both hemispheres 197.9
2223 Female, age 72, unknown 188.5
1942 Male, age 51, unknown 186.4
2021 Male, age 53, unknown 173.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

164.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 164.2
Samples: 139

Max nTPM: 269.1
Min nTPM: 109.9
Std nTPM: 32.2
Median nTPM: 158.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 269.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 264.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 256.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 252.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 235.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 232.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 230.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 226.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 225.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 223.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 220.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 219.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 216.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 215.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 207.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 203.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 202.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 201.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 201.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 200.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 197.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 196.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 196.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 194.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 194.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 188.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 186.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 185.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 183.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 182.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 182.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 181.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 180.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 180.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 180.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 180.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 179.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 176.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 175.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 173.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 173.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 173.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 172.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 172.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 172.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 171.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 170.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 170.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 170.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 170.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 170.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 168.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 167.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 167.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 167.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 166.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 165.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 165.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 164.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 164.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 162.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 162.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 161.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 161.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 160.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 159.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 159.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 159.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 158.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 158.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 157.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 157.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 157.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 157.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 157.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 156.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 155.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 154.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 154.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 153.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 153.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 152.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 148.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 148.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 148.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 148.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 148.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 147.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 146.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 146.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 146.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 146.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 146.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 146.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 146.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 145.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 145.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 145.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 145.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 144.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 142.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 141.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 140.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 140.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 140.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 140.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 140.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 138.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 138.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 138.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 137.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 137.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 137.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 137.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 136.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 136.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 136.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 134.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 134.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 133.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 132.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 132.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 132.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 131.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 129.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 129.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 128.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 128.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 126.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 126.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 122.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 122.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 121.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 120.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 119.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 118.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 115.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 115.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 109.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

439.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 439.0
FF:10158-103A5 76 years, female 439.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

232.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 210.1
Samples: 4

Max nTPM: 252.3
Min nTPM: 178.2
Sample A Female 252.3
Sample B Female 212.2
Sample C Male 197.6
Sample D Male 178.2
Midbrain
nTPM: 230.0
Samples: 4

Max nTPM: 278.0
Min nTPM: 194.9
Sample A Female 278.0
Sample B Female 226.1
Sample C Male 220.8
Sample D Male 194.9
Periaqueductal gray
nTPM: 180.1
Samples: 3

Max nTPM: 187.9
Min nTPM: 168.3
Sample B Female 187.9
Sample C Male 184.1
Sample D Male 168.3
Superior colliculi
nTPM: 232.6
Samples: 4

Max nTPM: 252.0
Min nTPM: 213.0
Sample A Female 247.4
Sample B Female 217.8
Sample C Male 252.0
Sample D Male 213.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

125.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 125.7
Samples: 4

Max nTPM: 134.0
Min nTPM: 121.1
Sample A Male 121.1
Sample B Male 123.5
Sample C Female 134.0
Sample D Female 124.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

12.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.0
72182999 Antisense, RP_050927_03_B03, Mouse strain C57BL/6J (56 days, male) 12.0

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