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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:46.7 nTPM
HPA Brain:104.7 nTPM
GTEx:46.7 nTPM
FANTOM5:120.2 Scaled Tags Per Million
Pig:132.4 nTPM
Mouse:284.8 nTPM
Allen mouse:14.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

104.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 87.4
2019 Male, age 18, unknown 114.9
2411 Female, age 72, unknown 98.8
1827 Male, age 72, unknown 97.9
2586 Male, age 75, left hemisphere 90.5
2219 Male, age 76, both hemispheres 89.2
2828 Female, age 72, unknown 83.4
1833 Male, age 53, unknown 78.9
1870 Female, age 42, unknown 78.6
1830 Male, age 51, unknown 71.7
2666 Male, age 74, left hemisphere 69.9
Dorsal raphe nucleus
nTPM: 94.0
2298 Female, age 72, unknown 112.5
1828 Male, age 53, unknown 110.0
2047 Male, age 72, unknown 93.8
2750 Male, age 76, both hemispheres 79.3
2016 Female, age 72, unknown 74.6
Inferior colliculus
nTPM: 89.3
2097 Female, age 72, unknown 104.9
1890 Male, age 53, unknown 93.3
1848 Female, age 42, unknown 88.0
2849 Male, age 72, unknown 70.8
Median raphe nucleus
nTPM: 74.2
2220 Male, age 76, midline 74.2
Periaquaductal grey, anterior
nTPM: 86.3
1947 Male, age 18, unknown 93.0
1795 Male, age 51, unknown 87.5
2502 Female, age 75, unknown 78.4
Periaquaductal grey, dorsal
nTPM: 67.3
2464 Female, age 72, unknown 68.7
1840 Male, age 53, unknown 68.1
1831 Male, age 72, unknown 67.6
2850 Male, age 76, both hemispheres 64.7
Periaquaductal grey, lateral
nTPM: 75.8
2272 Male, age 74, both hemispheres 100.1
2053 Male, age 18, unknown 64.1
2140 Male, age 76, both hemispheres 63.0
Pretectal area
nTPM: 97.0
2007 Male, age 72, unknown 131.2
1817 Female, age 42, unknown 119.8
1816 Male, age 51, unknown 115.3
1944 Female, age 72, unknown 114.0
2667 Female, age 75, unknown 109.1
2273 Male, age 74, both hemispheres 102.9
1815 Male, age 53, unknown 90.9
2224 Female, age 72, unknown 83.8
2316 Male, age 76, right hemisphere 70.7
2825 Male, age 18, unknown 68.2
2407 Male, age 75, both hemispheres 61.4
Red nucleus
nTPM: 91.4
1821 Female, age 72, unknown 115.6
2785 Male, age 18, unknown 107.5
2725 Female, age 75, unknown 102.5
2503 Female, age 72, unknown 96.8
2769 Male, age 72, unknown 94.0
1954 Female, age 42, unknown 89.7
2227 Male, age 72, unknown 89.3
2823 Male, age 76, right hemisphere 85.5
1865 Male, age 51, unknown 82.4
2588 Male, age 74, left hemisphere 82.1
1904 Male, age 53, unknown 81.9
2584 Male, age 75, left hemisphere 69.8
Substantia nigra
nTPM: 104.7
1916 Female, age 42, unknown 153.4
1941 Male, age 53, unknown 121.9
1851 Male, age 51, unknown 121.3
1889 Female, age 72, unknown 119.4
2409 Female, age 72, unknown 95.7
2665 Male, age 74, both hemispheres 94.4
2241 Male, age 72, unknown 93.9
2699 Male, age 18, unknown 89.9
2590 Female, age 75, unknown 79.7
2583 Male, age 75, right hemisphere 77.7
Superior colliculus
nTPM: 78.5
2087 Female, age 72, unknown 97.8
1796 Male, age 53, unknown 89.9
1895 Male, age 76, right hemisphere 87.5
2668 Female, age 75, unknown 83.8
2261 Male, age 18, unknown 82.8
2587 Male, age 74, left hemisphere 80.8
1839 Male, age 51, unknown 75.8
1995 Male, age 72, unknown 64.5
1913 Female, age 42, unknown 64.4
2664 Male, age 75, both hemispheres 58.0
Ventral tegmental area
nTPM: 92.8
2410 Female, age 72, unknown 119.5
1915 Female, age 42, unknown 112.4
2218 Male, age 76, both hemispheres 101.7
1942 Male, age 51, unknown 83.6
2223 Female, age 72, unknown 74.5
2021 Male, age 53, unknown 65.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

46.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 46.7
Samples: 139

Max nTPM: 141.4
Min nTPM: 13.7
Std nTPM: 18.9
Median nTPM: 43.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 141.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 119.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 90.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 88.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 87.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 84.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 82.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 81.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 81.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 81.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 74.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 74.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 70.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 69.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 68.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 68.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 67.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 65.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 64.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 64.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 64.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 62.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 62.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 62.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 61.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 60.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 59.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 58.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 58.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 58.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 57.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 56.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 56.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 56.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 55.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 55.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 54.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 54.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 53.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 52.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 52.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 51.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 50.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 50.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 50.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 50.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 49.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 49.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 49.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 48.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 48.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 48.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 48.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 47.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 47.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 46.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 46.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 46.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 45.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 45.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 45.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 45.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 44.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 44.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 44.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 44.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 43.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 43.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 43.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 43.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 43.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 43.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 43.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 43.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 42.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 42.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 42.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 42.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 41.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 41.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 41.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 41.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 41.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 41.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 40.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 40.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 40.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 39.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 38.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 38.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 38.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 37.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 36.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 36.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 36.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 35.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 35.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 35.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 35.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 35.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 34.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 34.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 34.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 34.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 34.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 34.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 33.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 33.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 33.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 33.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 32.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 32.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 32.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 32.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 32.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 31.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 31.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 30.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 30.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 30.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 29.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 29.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 28.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 28.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 27.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 27.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 26.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 25.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 25.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 25.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 24.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 23.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 23.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 21.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 20.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 17.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 16.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 14.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 13.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

120.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 120.2
FF:10158-103A5 76 years, female 120.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

132.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 95.7
Samples: 4

Max nTPM: 130.8
Min nTPM: 76.2
Sample A Female 130.8
Sample B Female 76.3
Sample C Male 99.5
Sample D Male 76.2
Midbrain
nTPM: 115.6
Samples: 4

Max nTPM: 146.9
Min nTPM: 93.5
Sample A Female 116.5
Sample B Female 93.5
Sample C Male 146.9
Sample D Male 105.3
Periaqueductal gray
nTPM: 83.9
Samples: 3

Max nTPM: 94.0
Min nTPM: 69.4
Sample B Female 88.3
Sample C Male 94.0
Sample D Male 69.4
Superior colliculi
nTPM: 132.4
Samples: 4

Max nTPM: 160.9
Min nTPM: 105.1
Sample A Female 155.4
Sample B Female 105.1
Sample C Male 160.9
Sample D Male 108.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

284.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 284.8
Samples: 4

Max nTPM: 304.9
Min nTPM: 267.1
Sample A Male 304.9
Sample B Male 273.7
Sample C Female 267.1
Sample D Female 293.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

14.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.3
68744540 Antisense, RP_050208_01_B03, Mouse strain C57BL/6J (56 days, male) 14.3

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