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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:194.6 nTPM
HPA Brain:193.4 nTPM
GTEx:194.6 nTPM
FANTOM5:28.6 Scaled Tags Per Million
Pig:325.7 nTPM
Mouse:259.2 nTPM
Allen mouse:4.6 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

193.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 146.6
2411 Female, age 72, unknown 184.5
1870 Female, age 42, unknown 172.3
1830 Male, age 51, unknown 169.1
2019 Male, age 18, unknown 166.4
1833 Male, age 53, unknown 150.0
2666 Male, age 74, left hemisphere 148.8
2828 Female, age 72, unknown 142.9
1827 Male, age 72, unknown 138.7
2219 Male, age 76, both hemispheres 107.4
2586 Male, age 75, left hemisphere 86.3
Dorsal raphe nucleus
nTPM: 118.9
2750 Male, age 76, both hemispheres 243.1
1828 Male, age 53, unknown 100.8
2298 Female, age 72, unknown 86.0
2016 Female, age 72, unknown 82.2
2047 Male, age 72, unknown 82.2
Inferior colliculus
nTPM: 107.6
1848 Female, age 42, unknown 118.5
2849 Male, age 72, unknown 112.9
2097 Female, age 72, unknown 101.4
1890 Male, age 53, unknown 97.5
Median raphe nucleus
nTPM: 141.0
2220 Male, age 76, midline 141.0
Periaquaductal grey, anterior
nTPM: 104.4
1947 Male, age 18, unknown 114.7
2502 Female, age 75, unknown 101.7
1795 Male, age 51, unknown 96.8
Periaquaductal grey, dorsal
nTPM: 81.7
2464 Female, age 72, unknown 105.7
1831 Male, age 72, unknown 100.2
1840 Male, age 53, unknown 68.0
2850 Male, age 76, both hemispheres 52.9
Periaquaductal grey, lateral
nTPM: 92.4
2272 Male, age 74, both hemispheres 121.0
2053 Male, age 18, unknown 102.3
2140 Male, age 76, both hemispheres 53.7
Pretectal area
nTPM: 131.9
1817 Female, age 42, unknown 183.0
1815 Male, age 53, unknown 181.5
2007 Male, age 72, unknown 172.2
1944 Female, age 72, unknown 168.1
2316 Male, age 76, right hemisphere 138.7
1816 Male, age 51, unknown 123.0
2825 Male, age 18, unknown 112.1
2273 Male, age 74, both hemispheres 109.5
2407 Male, age 75, both hemispheres 104.6
2224 Female, age 72, unknown 98.3
2667 Female, age 75, unknown 59.9
Red nucleus
nTPM: 193.4
2823 Male, age 76, right hemisphere 238.7
1865 Male, age 51, unknown 238.6
2588 Male, age 74, left hemisphere 215.1
1904 Male, age 53, unknown 204.4
2725 Female, age 75, unknown 200.9
2785 Male, age 18, unknown 198.7
2503 Female, age 72, unknown 188.9
1954 Female, age 42, unknown 182.5
1821 Female, age 72, unknown 179.2
2227 Male, age 72, unknown 170.7
2769 Male, age 72, unknown 169.5
2584 Male, age 75, left hemisphere 134.0
Substantia nigra
nTPM: 100.5
1889 Female, age 72, unknown 159.4
2590 Female, age 75, unknown 140.4
2583 Male, age 75, right hemisphere 107.2
1851 Male, age 51, unknown 104.3
2409 Female, age 72, unknown 99.1
1941 Male, age 53, unknown 85.8
1916 Female, age 42, unknown 85.0
2241 Male, age 72, unknown 82.2
2665 Male, age 74, both hemispheres 75.3
2699 Male, age 18, unknown 66.3
Superior colliculus
nTPM: 154.0
2668 Female, age 75, unknown 209.6
1913 Female, age 42, unknown 182.8
2587 Male, age 74, left hemisphere 171.6
1995 Male, age 72, unknown 163.4
2087 Female, age 72, unknown 158.5
2261 Male, age 18, unknown 156.9
1796 Male, age 53, unknown 156.0
1895 Male, age 76, right hemisphere 154.7
1839 Male, age 51, unknown 115.5
2664 Male, age 75, both hemispheres 71.1
Ventral tegmental area
nTPM: 123.7
2223 Female, age 72, unknown 170.2
2218 Male, age 76, both hemispheres 126.3
2410 Female, age 72, unknown 125.0
2021 Male, age 53, unknown 110.2
1942 Male, age 51, unknown 109.1
1915 Female, age 42, unknown 101.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

194.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 194.6
Samples: 139

Max nTPM: 904.7
Min nTPM: 29.8
Std nTPM: 147.0
Median nTPM: 154.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 904.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 807.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 714.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 645.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 633.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 538.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 451.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 451.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 423.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 410.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 408.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 406.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 388.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 368.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 358.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 354.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 347.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 336.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 325.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 317.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 306.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 304.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 304.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 299.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 298.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 280.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 279.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 270.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 266.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 239.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 238.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 237.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 236.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 236.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 225.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 222.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 217.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 215.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 215.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 213.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 211.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 210.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 207.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 207.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 206.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 204.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 204.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 201.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 201.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 199.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 193.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 191.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 189.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 186.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 186.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 183.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 178.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 177.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 176.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 176.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 171.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 169.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 168.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 168.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 164.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 163.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 159.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 156.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 156.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 154.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 151.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 149.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 148.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 148.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 147.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 144.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 144.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 144.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 142.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 141.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 140.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 138.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 136.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 135.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 133.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 131.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 126.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 126.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 126.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 125.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 124.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 122.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 118.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 116.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 115.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 113.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 110.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 109.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 109.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 108.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 105.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 105.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 102.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 101.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 101.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 100.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 98.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 98.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 95.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 94.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 94.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 93.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 89.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 87.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 85.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 84.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 83.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 83.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 83.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 82.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 81.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 81.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 78.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 76.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 63.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 59.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 56.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 55.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 52.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 49.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 49.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 49.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 47.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 46.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 39.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 39.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 37.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 32.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 29.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

28.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 28.6
FF:10158-103A5 76 years, female 28.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

325.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 254.9
Samples: 4

Max nTPM: 398.1
Min nTPM: 138.8
Sample A Female 263.2
Sample B Female 138.8
Sample C Male 219.4
Sample D Male 398.1
Midbrain
nTPM: 325.8
Samples: 4

Max nTPM: 570.3
Min nTPM: 214.5
Sample A Female 570.3
Sample B Female 260.6
Sample C Male 257.6
Sample D Male 214.5
Periaqueductal gray
nTPM: 184.9
Samples: 3

Max nTPM: 200.7
Min nTPM: 166.4
Sample B Female 200.7
Sample C Male 166.4
Sample D Male 187.6
Superior colliculi
nTPM: 254.9
Samples: 4

Max nTPM: 312.2
Min nTPM: 136.6
Sample A Female 281.7
Sample B Female 136.6
Sample C Male 289.0
Sample D Male 312.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

259.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 259.2
Samples: 4

Max nTPM: 275.1
Min nTPM: 248.4
Sample A Male 275.1
Sample B Male 248.4
Sample C Female 253.4
Sample D Female 259.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.6
1007 Antisense, RP_Baylor_103218, Mouse strain C57BL/6J (56 days, male) 8.3
1006 Antisense, RP_Baylor_103218, Mouse strain C57BL/6J (56 days, male) 7.7
1008 Sense, RPS_Baylor_37084, Mouse strain C57BL/6J (56 days, male) 0.8

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org