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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
78.0
nTPM
HPA:
78.0
nTPM
GTEx:
48.4
nTPM
FANTOM5:
210.1
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA027320
Antibody HPA055557
Cholangiocytes
Medium
Medium
Hepatocytes
High
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
78.0
Female, age 60
Liver sample 21 nTPM: 75.3
Male, age 54
Liver sample 23 nTPM: 66.9
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 76.7
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 96.4
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 78.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 71.6
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 75.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 69.9
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 84.4
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 84.2
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
48.4
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 48.4
Samples: 226
Max nTPM: 187.7
Min nTPM: 13.9
Std nTPM: 22.2
Median nTPM: 44.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
187.7
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
115.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
100.1
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
97.4
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
96.2
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
95.1
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
93.4
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
93.1
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
92.1
GTEX-S32W-1926-SM-4AD63
50-59 years, female
88.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
86.4
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
86.3
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
85.6
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
85.1
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
84.4
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
84.2
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
83.9
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
83.2
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
82.9
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
82.8
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
80.4
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
80.0
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
79.7
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
78.7
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
77.1
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
75.8
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
74.4
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
73.8
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
73.5
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
73.4
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
72.6
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
72.3
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
72.2
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
70.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
70.5
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
70.4
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
69.4
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
68.9
GTEX-R53T-0326-SM-48FEC
50-59 years, female
68.7
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
68.0
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
66.8
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
66.5
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
66.4
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
66.3
GTEX-17HHE-0126-SM-79398
50-59 years, male
65.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
65.4
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
64.7
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
64.6
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
64.1
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
63.7
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
62.9
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
62.8
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
62.6
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
62.5
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
62.0
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
61.8
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
61.5
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
61.3
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
60.7
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
60.7
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
59.5
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
58.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
57.6
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
57.6
GTEX-QESD-2026-SM-447BI
20-29 years, male
57.5
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
57.3
GTEX-18A66-2026-SM-7189C
60-69 years, male
57.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
57.2
GTEX-P78B-1326-SM-3P611
40-49 years, female
56.9
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
56.1
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
55.6
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
55.2
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
55.2
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
55.2
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
55.1
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
54.7
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
54.6
GTEX-14PHX-0526-SM-664NW
50-59 years, male
54.3
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
54.1
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
53.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
53.9
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
53.7
GTEX-Q734-0326-SM-48U15
40-49 years, female
53.7
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
53.6
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
53.3
GTEX-1B932-1426-SM-793AN
40-49 years, female
53.0
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
51.6
GTEX-O5YV-0726-SM-EV798
60-69 years, female
51.4
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
50.8
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
50.8
GTEX-14JG1-1626-SM-664NH
40-49 years, male
50.7
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
50.4
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
50.4
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
50.4
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
50.4
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
50.3
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
49.5
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
49.3
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
49.2
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
48.9
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
47.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
46.9
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
46.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
46.3
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
46.2
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
45.7
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
45.5
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
45.3
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
45.1
GTEX-13113-1326-SM-5GCOI
60-69 years, female
44.8
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
44.8
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
44.6
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
44.5
GTEX-12696-0826-SM-5EGGE
60-69 years, male
44.2
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
44.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
44.1
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
43.9
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
43.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
43.7
GTEX-RU72-1426-SM-46MUF
50-59 years, female
42.4
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
42.1
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
42.0
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
41.4
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
41.3
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
41.2
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
41.0
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
41.0
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
40.8
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
40.5
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
40.5
GTEX-1399T-0826-SM-5IFES
60-69 years, male
40.4
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
40.2
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
39.7
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
39.6
GTEX-14PJO-1726-SM-68719
60-69 years, male
39.5
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
39.4
GTEX-17F96-1226-SM-79OK2
70-79 years, male
38.8
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
38.4
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
38.0
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
37.9
GTEX-X261-1726-SM-4PQYT
50-59 years, male
37.9
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
37.9
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
37.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
37.7
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
37.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
37.0
GTEX-14E7W-1526-SM-6871X
70-79 years, male
36.4
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
36.3
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
36.3
GTEX-18A7A-1526-SM-72D69
50-59 years, female
35.7
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
35.5
GTEX-13112-1426-SM-5EGH8
50-59 years, male
35.4
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
35.3
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
35.2
GTEX-11ZUS-2526-SM-59872
30-39 years, male
35.0
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
35.0
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
34.9
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
34.7
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
34.6
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
34.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
34.2
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
33.8
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
33.4
GTEX-REY6-1226-SM-48FDR
60-69 years, male
33.3
GTEX-S33H-1626-SM-4AD68
30-39 years, male
33.3
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
32.3
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
32.2
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
31.9
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
31.7
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
31.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
31.5
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
31.2
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
31.2
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
30.9
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
30.2
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
30.2
GTEX-1B933-1226-SM-731DW
50-59 years, female
30.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
29.7
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
29.1
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
29.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
28.7
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
28.4
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
28.3
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
27.8
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
27.7
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
27.7
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
27.5
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
27.3
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
27.0
GTEX-YECK-1926-SM-4W21H
60-69 years, male
26.8
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
26.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
26.7
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
26.6
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
25.9
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
25.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
25.7
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
25.6
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
25.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
25.4
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
25.1
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
25.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
25.0
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
24.9
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
24.9
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
24.8
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
24.3
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
23.9
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
23.6
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
23.6
GTEX-18465-1626-SM-7LG6N
50-59 years, male
23.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
23.2
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
22.9
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
21.8
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
21.0
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
20.7
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
20.4
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
20.1
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
19.9
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
19.3
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
18.5
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
18.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
18.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
18.2
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
17.8
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
15.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
13.9
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
