CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Low
Glial cells: Low
Neuronal cells: Low
Neuropil: Not detected
RNA expressioni
Consensus:80.1 nTPM
HPA:7.7 nTPM
HPA Brain:34.1 nTPM
HPA PFC Brain:7.8 nTPM
GTEx:80.1 nTPM
FANTOM5:107.5 Scaled Tags Per Million
Pig:44.5 nTPM
Mouse:117.0 nTPM
Allen mouse:15.5 Expression energy

CEREBRAL CORTEX - Antibody stainingi
Antibody CAB037065
Endothelial cells Low
Glial cells Low
Neuronal cells Low
Neuropil Not detected



CEREBRAL CORTEX - HPA RNA-seqi
Average nTPMi 7.7
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 5
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 15.7
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 2.2
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max subtype nTPMi 34.1
Sample id Sample description nTPM
Angular gyrus
nTPM: 27.3
2221 Female, age 67, right hemisphere 32.2
2602 Female, age 94, right hemisphere 31.6
2260 Female, age 72, left hemisphere 30.5
2722 Male, age 61, left hemisphere 27.7
1866 Male, age 76, both hemispheres 26.7
1790 Male, age 76, right hemisphere 24.3
2265 Female, age 91, left hemisphere 23.8
2103 Male, age 75, left hemisphere 21.4
Anterior cingulate cortex, supragenual-dorsal
nTPM: 24.6
1896 Female, age 85, right hemisphere 28.2
2472 Male, age 75, left hemisphere 26.2
2342 Female, age 94, right hemisphere 25.7
2478 Female, age 67, right hemisphere 23.4
2547 Male, age 74, left hemisphere 19.5
Anterior cingulate cortex, supragenual-ventral
nTPM: 21.7
1755 Female, age 94, right hemisphere 28.0
2538 Male, age 75, left hemisphere 22.9
1950 Female, age 85, right hemisphere 21.2
1761 Male, age 74, left hemisphere 18.5
2479 Female, age 67, right hemisphere 17.8
Anterior insular cortex, dorsal
nTPM: 24.2
2506 Female, age 94, right hemisphere 33.8
2235 Female, age 91, right hemisphere 22.4
2001 Male, age 76, right hemisphere 20.5
2670 Male, age 75, left hemisphere 20.2
Anterior insular cortex, ventral
nTPM: 24.2
2757 Male, age 61, right hemisphere 31.1
1925 Female, age 91, left hemisphere 27.8
2507 Female, age 94, left hemisphere 23.0
2262 Female, age 67, right hemisphere 22.4
1852 Male, age 76, left hemisphere 20.3
2596 Male, age 75, left hemisphere 20.3
Area parastriata, inferior
nTPM: 22.8
1760 Female, age 67, left hemisphere 26.2
2268 Male, age 61, right hemisphere 25.9
1758 Female, age 72, right hemisphere 25.5
1789 Male, age 76, right hemisphere 24.6
2421 Female, age 91, left hemisphere 22.3
2509 Female, age 94, left hemisphere 20.6
2234 Male, age 75, left hemisphere 14.4
Area parastriata, parietal
nTPM: 28.1
2680 Female, age 94, right hemisphere 35.3
1785 Male, age 76, right hemisphere 34.3
2236 Female, age 91, left hemisphere 28.4
2233 Male, age 61, right hemisphere 22.2
2420 Male, age 75, left hemisphere 20.1
Area parastriata, superior
nTPM: 25.4
2881 Male, age 76, left hemisphere 49.4
1773 Female, age 91, left hemisphere 29.5
2419 Male, age 75, right hemisphere 23.2
2684 Female, age 67, left hemisphere 19.4
2604 Female, age 94, right hemisphere 16.9
2435 Male, age 61, left hemisphere 14.2
Area parastriata, temporal
nTPM: 25.8
1804 Male, age 76, right hemisphere 29.4
2267 Male, age 61, right hemisphere 26.0
2471 Male, age 75, left hemisphere 25.0
2681 Female, age 94, right hemisphere 24.4
2424 Female, age 67, left hemisphere 24.0
Area striata
nTPM: 24.7
2679 Female, age 94, right hemisphere 30.1
2427 Female, age 91, left hemisphere 30.0
1753 Female, age 72, right hemisphere 26.1
2417 Male, age 61, right hemisphere 24.5
2002 Female, age 91, right hemisphere 20.4
1884 Male, age 76, left hemisphere 17.2
Claustrum
nTPM: 20.8
2645 Female, age 72, unknown 28.5
2284 Female, age 91, both hemispheres 22.8
2491 Male, age 75, both hemispheres 21.9
1956 Male, age 74, unknown 21.0
2198 Male, age 80, both hemispheres 20.7
2392 Female, age 94, both hemispheres 20.1
2568 Male, age 61, both hemispheres 19.4
2196 Female, age 79, unknown 17.0
2292 Female, age 85, both hemispheres 15.5
Frontal eye field
nTPM: 25.1
2441 Male, age 75, left hemisphere 29.2
2761 Female, age 94, left hemisphere 26.6
2543 Male, age 74, left hemisphere 22.4
2147 Male, age 61, left hemisphere 22.2
Frontal operculum
nTPM: 21.5
2781 Female, age 85, right hemisphere 28.0
2030 Male, age 61, right hemisphere 18.3
2348 Male, age 75, left hemisphere 18.3
Fusiform gyrus
nTPM: 25.9
2784 Female, age 85, left hemisphere 33.6
2617 Female, age 94, left hemisphere 32.2
1807 Male, age 76, left hemisphere 28.7
2112 Male, age 80, both hemispheres 27.3
2074 Female, age 91, left hemisphere 25.2
2431 Male, age 75, right hemisphere 17.9
2433 Female, age 72, left hemisphere 16.8
Inferior frontal gyrus, opercular
nTPM: 23.5
2872 Female, age 94, right hemisphere 26.9
2867 Male, age 75, left hemisphere 25.4
2865 Male, age 61, left hemisphere 25.2
2871 Female, age 94, left hemisphere 24.9
2875 Female, age 67, left hemisphere 24.7
2873 Female, age 85, left hemisphere 24.3
2866 Male, age 61, right hemisphere 22.9
2868 Male, age 75, right hemisphere 21.8
2869 Male, age 74, left hemisphere 21.1
2874 Female, age 85, right hemisphere 18.3
Inferior parietal lobule
nTPM: 26.1
2876 Male, age 76, right hemisphere 32.3
2599 Female, age 94, left hemisphere 27.4
2418 Male, age 75, left hemisphere 24.5
2606 Female, age 67, right hemisphere 20.0
Inferior temporal gyrus
nTPM: 26.9
1965 Female, age 91, left hemisphere 33.8
1808 Male, age 76, left hemisphere 29.0
1970 Female, age 85, right hemisphere 27.8
2689 Female, age 94, right hemisphere 27.4
1880 Male, age 80, right hemisphere 24.8
2430 Male, age 75, right hemisphere 18.5
Intraparietal deep sulcus
nTPM: 22.3
2230 Male, age 61, right hemisphere 25.3
2600 Female, age 94, right hemisphere 24.9
2798 Male, age 76, left hemisphere 24.6
2102 Female, age 91, left hemisphere 24.0
2669 Male, age 75, left hemisphere 19.6
2607 Female, age 67, right hemisphere 15.6
Lingual gyrus
nTPM: 24.5
2838 Male, age 80, right hemisphere 26.6
1893 Male, age 76, left hemisphere 25.0
2618 Female, age 94, left hemisphere 24.9
2073 Female, age 85, left hemisphere 24.5
2688 Male, age 75, right hemisphere 21.5
Middle cingulate cortex
nTPM: 23.5
2357 Female, age 67, right hemisphere 31.5
2640 Female, age 94, right hemisphere 23.9
2028 Female, age 85, left hemisphere 23.8
2539 Male, age 75, left hemisphere 20.6
2633 Male, age 74, left hemisphere 17.9
Middle temporal gyrus
nTPM: 24.7
2034 Female, age 91, right hemisphere 31.7
1799 Male, age 76, left hemisphere 24.4
1819 Male, age 80, right hemisphere 23.5
2616 Female, age 94, left hemisphere 22.1
2611 Male, age 75, right hemisphere 21.7
Occipital cortex
nTPM: 29.6
1842 Male, age 76, right hemisphere 36.5
2608 Female, age 67, both hemispheres 32.8
2426 Male, age 75, midline 29.9
2470 Male, age 75, right hemisphere 25.7
2677 Female, age 67, right hemisphere 23.0
Olfactory area
nTPM: 26.1
2756 Female, age 67, right hemisphere 34.8
2222 Female, age 67, right hemisphere 32.0
2352 Female, age 94, right hemisphere 30.4
1805 Female, age 85, right hemisphere 24.5
2440 Male, age 75, left hemisphere 19.3
2542 Male, age 74, left hemisphere 15.3
Olfactory tubercle
nTPM: 24.6
1998 Female, age 91, both hemispheres 31.6
2487 Female, age 94, left hemisphere 23.3
2856 Male, age 75, right hemisphere 23.3
1846 Male, age 80, right hemisphere 20.1
Orbitofrontal gyrus, anterior
nTPM: 13.5
2862 Female, age 85, left hemisphere 15.3
2864 Female, age 67, left hemisphere 14.6
2863 Female, age 85, right hemisphere 10.6
Paracentral lobule, anterior
nTPM: 24.1
2638 Female, age 94, right hemisphere 29.0
2474 Male, age 74, left hemisphere 26.0
1926 Male, age 61, left hemisphere 24.9
2340 Female, age 67, right hemisphere 23.3
1754 Male, age 75, left hemisphere 22.7
1776 Female, age 85, right hemisphere 18.4
Paracentral lobule, posterior
nTPM: 21.5
1775 Female, age 85, right hemisphere 23.7
2551 Female, age 94, right hemisphere 23.2
2446 Male, age 75, left hemisphere 21.9
1764 Male, age 74, right hemisphere 20.1
2345 Male, age 61, left hemisphere 18.5
Parietal operculum
nTPM: 23.9
2552 Female, age 94, right hemisphere 28.5
2356 Female, age 67, right hemisphere 23.8
2719 Male, age 75, left hemisphere 22.8
1763 Male, age 74, left hemisphere 20.2
Parieto-insular cortex
nTPM: 24.9
2232 Male, age 61, right hemisphere 29.0
1976 Female, age 91, right hemisphere 27.3
2831 Male, age 76, right hemisphere 25.5
2508 Female, age 94, right hemisphere 24.2
2671 Male, age 75, left hemisphere 18.3
Parieto-occipital transitional area
nTPM: 24.9
2674 Female, age 94, right hemisphere 29.3
2270 Male, age 61, right hemisphere 26.9
1784 Male, age 76, right hemisphere 26.8
2468 Male, age 75, left hemisphere 23.0
2683 Female, age 67, left hemisphere 18.7
Piriform cortex
nTPM: 15.0
2347 Male, age 75, right hemisphere 17.2
2153 Female, age 85, left hemisphere 12.9
Postcentral gyrus
nTPM: 33.4
2533 Male, age 75, right hemisphere 33.4
Postcentral gyrus, dorsal
nTPM: 22.7
1836 Female, age 85, right hemisphere 26.1
2544 Male, age 74, left hemisphere 25.0
2477 Female, age 94, right hemisphere 24.1
2151 Male, age 61, left hemisphere 23.0
2350 Male, age 75, left hemisphere 19.7
2339 Female, age 67, right hemisphere 18.4
Postcentral gyrus, middle
nTPM: 28.3
2545 Male, age 74, left hemisphere 29.3
2146 Female, age 67, right hemisphere 29.2
1897 Female, age 85, right hemisphere 29.1
2444 Male, age 75, left hemisphere 27.7
2248 Male, age 61, left hemisphere 26.3
Postcentral gyrus, ventral
nTPM: 23.5
2836 Female, age 94, right hemisphere 27.7
2445 Male, age 75, left hemisphere 24.7
2024 Female, age 85, right hemisphere 18.2
Posterior cingulate cortex
nTPM: 22.5
2473 Male, age 75, left hemisphere 22.9
1759 Male, age 74, right hemisphere 22.6
2553 Female, age 94, right hemisphere 22.0
Posterior cingulate cortex, dorsal
nTPM: 21.1
2076 Female, age 85, right hemisphere 28.8
2641 Female, age 94, right hemisphere 25.1
2343 Male, age 61, left hemisphere 19.2
2540 Male, age 75, right hemisphere 18.9
2556 Female, age 67, right hemisphere 17.6
2634 Male, age 74, left hemisphere 17.0
Posterior cingulate cortex, ventral
nTPM: 23.4
1994 Female, age 85, right hemisphere 32.5
2346 Male, age 61, left hemisphere 25.4
1762 Female, age 94, right hemisphere 24.4
2541 Male, age 75, right hemisphere 20.5
2635 Male, age 74, left hemisphere 19.8
2448 Female, age 67, right hemisphere 18.0
Posterior insular cortex
nTPM: 26.1
2603 Female, age 94, left hemisphere 31.3
2511 Female, age 67, right hemisphere 28.6
2231 Male, age 61, left hemisphere 27.9
1823 Male, age 76, right hemisphere 27.4
2832 Female, age 91, right hemisphere 21.6
2597 Male, age 75, left hemisphere 19.8
Precentral gyrus
nTPM: 27.0
2557 Male, age 75, right hemisphere 27.0
Precentral gyrus, dorsal
nTPM: 24.2
2354 Female, age 67, right hemisphere 28.9
1756 Male, age 74, left hemisphere 23.7
2476 Female, age 94, right hemisphere 23.7
2442 Male, age 75, left hemisphere 20.3
Precentral gyrus, middle
nTPM: 27.1
2549 Female, age 94, right hemisphere 31.8
1969 Female, age 67, right hemisphere 31.6
2443 Male, age 75, left hemisphere 28.1
1909 Male, age 61, left hemisphere 25.2
2475 Male, age 74, right hemisphere 18.8
Precentral gyrus, ventral
nTPM: 23.3
2550 Female, age 94, right hemisphere 27.3
2630 Male, age 75, left hemisphere 23.2
2662 Female, age 67, right hemisphere 21.5
2678 Male, age 74, left hemisphere 21.2
Precuneus
nTPM: 24.9
1780 Female, age 91, right hemisphere 28.9
2673 Female, age 94, right hemisphere 27.6
2594 Male, age 61, left hemisphere 27.1
1782 Male, age 76, right hemisphere 26.1
2510 Female, age 67, right hemisphere 22.9
2467 Male, age 75, right hemisphere 16.9
Premotor cortex, dorsal
nTPM: 20.8
1878 Female, age 85, right hemisphere 27.1
2027 Male, age 61, left hemisphere 23.3
2631 Male, age 74, left hemisphere 19.7
2536 Male, age 75, left hemisphere 18.5
2554 Female, age 67, right hemisphere 15.6
Premotor cortex, ventral
nTPM: 24.6
2637 Female, age 94, right hemisphere 34.8
1881 Female, age 85, right hemisphere 29.6
2349 Male, age 75, left hemisphere 22.8
1757 Male, age 74, left hemisphere 20.8
1779 Male, age 61, left hemisphere 20.2
1777 Female, age 67, left hemisphere 19.3
Retrosplenial cortex
nTPM: 33.9
1951 Male, age 61, right hemisphere 40.9
1914 Male, age 76, right hemisphere 30.9
2675 Female, age 94, left hemisphere 30.0
Subcentral gyrus, S2
nTPM: 26.0
2839 Female, age 94, right hemisphere 29.9
1964 Female, age 85, right hemisphere 29.8
2072 Male, age 61, left hemisphere 29.4
2555 Female, age 67, right hemisphere 25.1
2762 Male, age 74, left hemisphere 22.7
2351 Male, age 75, left hemisphere 19.3
Superior parietal lobule
nTPM: 24.5
2229 Male, age 61, right hemisphere 29.6
2672 Female, age 94, right hemisphere 28.8
1992 Female, age 91, right hemisphere 22.7
2605 Female, age 67, right hemisphere 21.1
1800 Male, age 76, right hemisphere 20.4
Superior temporal gyrus
nTPM: 25.8
1844 Female, age 91, left hemisphere 34.8
1843 Male, age 76, left hemisphere 25.6
2615 Female, age 94, left hemisphere 25.4
2025 Male, age 80, right hemisphere 21.7
2687 Male, age 75, right hemisphere 21.6
Supplementary motor cortex
nTPM: 26.1
2548 Female, age 94, right hemisphere 31.0
2537 Male, age 75, left hemisphere 27.8
1993 Male, age 61, left hemisphere 25.4
2632 Male, age 74, left hemisphere 20.1
Supramarginal gyrus
nTPM: 31.7
1798 Male, age 76, right hemisphere 35.9
2513 Female, age 72, left hemisphere 32.9
2415 Male, age 61, left hemisphere 31.9
1991 Female, age 91, right hemisphere 29.8
2601 Female, age 94, left hemisphere 27.9
Temporal pole
nTPM: 22.5
1832 Female, age 91, left hemisphere 29.4
2612 Female, age 94, left hemisphere 25.4
1853 Female, age 85, right hemisphere 22.8
1826 Male, age 76, right hemisphere 17.6
2518 Male, age 75, right hemisphere 17.0
Temporo-insular cortex, parainsular gyrus
nTPM: 24.5
2676 Female, age 94, right hemisphere 29.0
2416 Male, age 61, right hemisphere 27.5
1802 Male, age 76, left hemisphere 26.8
2264 Female, age 91, right hemisphere 24.4
2512 Female, age 67, right hemisphere 20.7
2598 Male, age 75, left hemisphere 18.7
Temporo-occipital transitional zone
nTPM: 34.1
1900 Male, age 76, left hemisphere 49.0
1793 Male, age 80, right hemisphere 30.7
2251 Female, age 85, right hemisphere 22.6
Transversal temporal gyrus, anterior
nTPM: 27.7
1888 Female, age 91, left hemisphere 31.6
1809 Male, age 76, right hemisphere 30.7
2522 Female, age 94, left hemisphere 29.0
1910 Male, age 80, right hemisphere 25.3
2610 Male, age 75, right hemisphere 21.9
Transversal temporal gyrus, posterior
nTPM: 29.3
1967 Female, age 91, right hemisphere 38.1
2614 Female, age 94, left hemisphere 29.7
2833 Male, age 80, right hemisphere 29.1
1922 Male, age 76, left hemisphere 25.9
2520 Male, age 75, right hemisphere 23.6

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max subtype nTPMi 7.8
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 5.2
1514 Male, age 74, right hemisphere 16.7
1513 Male, age 74, left hemisphere 12.7
1512 Male, age 75, left hemisphere 11.4
1515 Female, age 94, right hemisphere 1.5
1517 Female, age 67, left hemisphere 1.5
1518 Female, age 67, right hemisphere 1.4
1510 Male, age 61, left hemisphere 1.2
1511 Male, age 61, right hemisphere 0.5
1516 Female, age 85, left hemisphere 0.2
Anterior cingulate gyrus, pregenual-ventral
nTPM: 7.8
1521 Male, age 74, left hemisphere 14.0
1520 Male, age 75, right hemisphere 11.5
1522 Male, age 74, right hemisphere 10.5
1519 Male, age 61, left hemisphere 1.4
1523 Female, age 67, left hemisphere 1.4
Anterior cingulate gyrus, subgenual
nTPM: 7.7
1525 Male, age 75, left hemisphere 14.3
1527 Male, age 74, left hemisphere 13.9
1528 Male, age 74, right hemisphere 12.1
1526 Male, age 75, right hemisphere 11.8
1524 Male, age 61, left hemisphere 1.2
1529 Female, age 85, left hemisphere 0.4
1530 Female, age 67, right hemisphere 0.2
Dorsolateral prefrontal cortex
nTPM: 5.7
1446 Male, age 74, right hemisphere 13.6
1445 Male, age 75, right hemisphere 13.1
1444 Male, age 75, left hemisphere 10.7
1450 Female, age 67, right hemisphere 0.9
1449 Female, age 85, right hemisphere 0.8
1448 Female, age 94, right hemisphere 0.4
1447 Female, age 94, left hemisphere 0.2
Dorsomedial prefrontal cortex
nTPM: 6.4
1442 Male, age 75, right hemisphere 16.1
1441 Male, age 75, left hemisphere 13.7
1443 Female, age 67, right hemisphere 1.1
1440 Male, age 61, right hemisphere 0.7
1439 Male, age 61, left hemisphere 0.5
Frontal cortex
nTPM: 3.8
1574 Male, age 75, left hemisphere 12.3
1575 Male, age 75, right hemisphere 11.6
1577 Male, age 74, right hemisphere 9.5
1576 Male, age 74, left hemisphere 7.8
1578 Female, age 94, left hemisphere 1.8
1572 Male, age 61, left hemisphere 1.1
1583 Female, age 67, right hemisphere 0.7
1581 Female, age 85, right hemisphere 0.4
1573 Male, age 61, right hemisphere 0.3
1579 Female, age 94, right hemisphere 0.3
1580 Female, age 85, left hemisphere 0.1
1582 Female, age 67, left hemisphere 0.1
Frontomarginal cortex
nTPM: 3.8
1468 Male, age 74, left hemisphere 13.9
1467 Male, age 75, right hemisphere 9.6
1469 Female, age 94, left hemisphere 6.1
1473 Female, age 67, right hemisphere 1.2
1470 Female, age 94, right hemisphere 0.9
1472 Female, age 67, left hemisphere 0.9
1466 Male, age 61, right hemisphere 0.8
1465 Male, age 61, left hemisphere 0.7
1471 Female, age 85, left hemisphere 0.2
Frontopolar cortex
nTPM: 4.1
1461 Male, age 75, right hemisphere 12.9
1460 Male, age 75, left hemisphere 9.1
1463 Female, age 67, left hemisphere 2.4
1462 Female, age 94, left hemisphere 1.9
1458 Male, age 61, left hemisphere 1.1
1459 Male, age 61, right hemisphere 0.9
1464 Female, age 67, right hemisphere 0.6
Gyrus rectus
nTPM: 3.0
1476 Male, age 75, left hemisphere 9.1
1477 Male, age 75, right hemisphere 6.5
1479 Female, age 94, right hemisphere 3.1
1478 Female, age 94, left hemisphere 1.9
1481 Female, age 67, left hemisphere 1.4
1474 Male, age 61, left hemisphere 1.2
1475 Male, age 61, right hemisphere 0.7
1480 Female, age 85, left hemisphere 0.1
Inferior frontal gyrus, orbital
nTPM: 6.4
1502 Male, age 75, left hemisphere 16.6
1504 Male, age 74, left hemisphere 16.4
1503 Male, age 75, right hemisphere 12.7
1505 Male, age 74, right hemisphere 12.0
1507 Female, age 85, left hemisphere 2.1
1501 Male, age 61, right hemisphere 1.2
1506 Female, age 94, left hemisphere 0.9
1509 Female, age 67, right hemisphere 0.8
1500 Male, age 61, left hemisphere 0.7
1508 Female, age 85, right hemisphere 0.3
Inferior frontal gyrus, triangular
nTPM: 4.2
1545 Male, age 74, right hemisphere 17.2
1544 Male, age 75, right hemisphere 13.4
1542 Male, age 61, left hemisphere 1.1
1547 Female, age 85, left hemisphere 1.0
1549 Female, age 67, left hemisphere 0.4
1546 Female, age 94, right hemisphere 0.3
1543 Male, age 61, right hemisphere 0.2
1548 Female, age 85, right hemisphere 0.0
Orbitofrontal gyrus, lateral
nTPM: 3.0
1494 Male, age 75, left hemisphere 16.0
1495 Female, age 94, left hemisphere 1.9
1493 Male, age 61, right hemisphere 1.0
1496 Female, age 94, right hemisphere 0.9
1499 Female, age 67, right hemisphere 0.8
1498 Female, age 85, right hemisphere 0.6
1497 Female, age 85, left hemisphere 0.1
Orbitofrontal gyrus, medial
nTPM: 2.9
1485 Male, age 74, left hemisphere 8.6
1483 Male, age 75, left hemisphere 6.5
1486 Male, age 74, right hemisphere 5.4
1484 Male, age 75, right hemisphere 4.7
1487 Female, age 94, left hemisphere 1.3
1491 Female, age 67, left hemisphere 1.2
1492 Female, age 67, right hemisphere 0.9
1482 Male, age 61, left hemisphere 0.8
1490 Female, age 85, right hemisphere 0.8
1488 Female, age 94, right hemisphere 0.6
1489 Female, age 85, left hemisphere 0.6
Orbitofrontal gyrus, posterior
nTPM: 4.4
1535 Male, age 74, left hemisphere 15.7
1533 Male, age 75, left hemisphere 15.5
1534 Male, age 75, right hemisphere 11.2
1536 Female, age 94, left hemisphere 1.7
1537 Female, age 94, right hemisphere 0.9
1541 Female, age 67, right hemisphere 0.8
1531 Male, age 61, left hemisphere 0.7
1539 Female, age 85, right hemisphere 0.6
1532 Male, age 61, right hemisphere 0.5
1540 Female, age 67, left hemisphere 0.4
1538 Female, age 85, left hemisphere 0.3
Subcallosal gyrus
nTPM: 3.7
1555 Male, age 74, right hemisphere 10.6
1552 Male, age 75, left hemisphere 9.3
1554 Male, age 74, left hemisphere 8.9
1553 Male, age 75, right hemisphere 8.1
1561 Female, age 67, right hemisphere 2.1
1557 Female, age 94, right hemisphere 1.5
1550 Male, age 61, left hemisphere 1.2
1551 Male, age 61, right hemisphere 0.5
1559 Female, age 85, right hemisphere 0.5
1556 Female, age 94, left hemisphere 0.4
1558 Female, age 85, left hemisphere 0.4
1560 Female, age 67, left hemisphere 0.4
Superior frontal gyrus
nTPM: 3.6
1564 Male, age 75, left hemisphere 11.4
1566 Male, age 74, right hemisphere 10.1
1565 Male, age 75, right hemisphere 9.0
1571 Female, age 67, right hemisphere 1.4
1562 Male, age 61, left hemisphere 1.3
1570 Female, age 85, right hemisphere 1.0
1568 Female, age 94, right hemisphere 0.8
1563 Male, age 61, right hemisphere 0.6
1569 Female, age 85, left hemisphere 0.3
1567 Female, age 94, left hemisphere 0.1
Temporal cortex
nTPM: 4.3
1593 Male, age 74, right hemisphere 10.7
1592 Male, age 74, left hemisphere 9.6
1591 Male, age 75, right hemisphere 6.7
1594 Female, age 94, left hemisphere 1.8
1590 Male, age 61, right hemisphere 0.6
1596 Female, age 85, right hemisphere 0.3
1595 Female, age 94, right hemisphere 0.1
Ventrolateral prefrontal cortex
nTPM: 4.8
1451 Male, age 75, right hemisphere 11.3
1453 Male, age 74, right hemisphere 10.9
1452 Male, age 74, left hemisphere 8.8
1457 Female, age 67, right hemisphere 1.4
1454 Female, age 94, left hemisphere 0.8
1455 Female, age 85, right hemisphere 0.2
1456 Female, age 67, left hemisphere 0.1
Ventromedial prefrontal cortex
nTPM: 1.6
1434 Male, age 75, right hemisphere 8.4
1432 Male, age 61, left hemisphere 1.0
1433 Male, age 61, right hemisphere 0.9
1437 Female, age 85, right hemisphere 0.5
1436 Female, age 85, left hemisphere 0.4
1438 Female, age 67, left hemisphere 0.2
1435 Female, age 94, right hemisphere 0.0

CEREBRAL CORTEX - GTEx RNA-seqi
Max subtype nTPMi 80.1
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 65.3
Samples: 176

Max nTPM: 117.9
Min nTPM: 9.9
Std nTPM: 19.0
Median nTPM: 65.9
GTEX-WL46-0011-R3A-SM-3TW8E 50-59 years, male 117.9
GTEX-145MH-0011-R3b-SM-5P9JQ 50-59 years, male 114.9
GTEX-YFC4-0011-R3a-SM-4RGLP 40-49 years, female 112.4
GTEX-11GSO-0011-R3b-SM-57WB2 60-69 years, male 106.8
GTEX-RNOR-0011-R3A-SM-5SI8E 50-59 years, female 105.6
GTEX-14PN4-0011-R3b-SM-686ZU 50-59 years, male 104.3
GTEX-1313W-0011-R3a-SM-5EGLI 50-59 years, female 103.2
GTEX-12WSC-0011-R3a-SM-5P9F1 50-59 years, male 101.4
GTEX-P44G-0011-R3A-SM-2I3FC 30-39 years, male 101.3
GTEX-131XH-0011-R3b-SM-5DUWM 50-59 years, male 99.3
GTEX-1B8L1-0011-R3a-SM-7EPIO 60-69 years, male 99.0
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Brain - Cortex
Average nTPM: 80.1
Samples: 255

Max nTPM: 134.6
Min nTPM: 31.1
Std nTPM: 19.9
Median nTPM: 82.2
GTEX-WL46-2926-SM-3LK82 50-59 years, male 134.6
GTEX-13SLX-3126-SM-5S2Q5 50-59 years, female 127.2
GTEX-Z93S-2926-SM-57WB9 50-59 years, male 121.8
GTEX-1B933-3126-SM-7P8RL 50-59 years, female 118.8
GTEX-12WSC-3026-SM-5GCNF 50-59 years, male 116.6
GTEX-11ZUS-2926-SM-5FQSL 30-39 years, male 115.8
GTEX-117XS-3026-SM-5N9CA 60-69 years, male 115.6
GTEX-1313W-3126-SM-5LZUI 50-59 years, female 115.2
GTEX-13O3O-3126-SM-5KM3H 60-69 years, female 113.1
GTEX-1EMGI-3026-SM-7P8P6 60-69 years, male 112.8
GTEX-12WSF-3126-SM-6M478 70-79 years, male 112.4
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Brain - Frontal Cortex (BA9)
Average nTPM: 79.7
Samples: 209

Max nTPM: 132.5
Min nTPM: 10.7
Std nTPM: 22.6
Median nTPM: 82.6
GTEX-13QJC-0011-R10a-SM-5SI63 60-69 years, female 132.5
GTEX-13SLX-0011-R10a-SM-5P9HV 50-59 years, female 126.5
GTEX-1EX96-0011-R10b-SM-CE6QR 50-59 years, male 120.1
GTEX-18A6Q-0011-R10b-SM-72D7A 60-69 years, male 118.8
GTEX-13O3O-0011-R10a-SM-5LUA9 60-69 years, female 117.5
GTEX-145MG-0011-R10a-SM-5PNWG 50-59 years, male 116.7
GTEX-13RTJ-0011-R10b-SM-5O9CW 60-69 years, male 116.3
GTEX-12WSC-0011-R10a-SM-5GU57 50-59 years, male 114.9
GTEX-1GF9V-0011-R10b-SM-CKZNP 60-69 years, male 114.9
GTEX-1J8Q2-0011-R10b-SM-D4P2C 60-69 years, male 114.7
GTEX-1H4P4-0011-R10b-SM-CE6SG 50-59 years, male 114.3
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 107.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 46.4
FF:10163-103B1 76 years, female 46.4
Postcentral gyrus
Scaled Tags Per Million: 95.9
FF:10032-101E5 44-52 years, mixed 95.9
Frontal lobe
Scaled Tags Per Million: 72.8
FF:10040-101F4 32-61 years, mixed 72.8
Insula
Scaled Tags Per Million: 83.2
FF:10039-101F3 20-68 years, mixed 83.2
Medial frontal gyrus
Scaled Tags Per Million: 58.3
FF:10150-102I6 76 years, female 58.3
Medial temporal gyrus
Scaled Tags Per Million: 81.5
FF:10183-103D3 60 years, female 110.1
FF:10156-103A3 76 years, female 52.9
Occipital lobe
Scaled Tags Per Million: 101.5
FF:10076-102A4 27 years, male 101.5
Occipital pole
Scaled Tags Per Million: 98.5
FF:10036-101E9 22-68 years, mixed 98.5
Paracentral gyrus
Scaled Tags Per Million: 73.8
FF:10035-101E8 22-69 years, mixed 73.8
Parietal lobe
Scaled Tags Per Million: 76.3
FF:10171-103B9 60 years, female 90.8
FF:10034-101E7 35-89 years, mixed 75.7
FF:10157-103A4 76 years, female 62.3
Temporal lobe
Scaled Tags Per Million: 107.5
FF:10031-101E4 32-61 years, mixed 107.5

CEREBRAL CORTEX - Pig RNA-seqi
Max subtype nTPMi 44.5
Pig sample Sample description nTPM
Occipital cortex
nTPM: 40.2
Samples: 4

Max nTPM: 45.6
Min nTPM: 36.3
Sample A Female 41.2
Sample B Female 36.3
Sample C Male 45.6
Sample D Male 37.7
Retrosplenial cortex
nTPM: 37.2
Samples: 4

Max nTPM: 44.0
Min nTPM: 31.3
Sample A Female 37.4
Sample B Female 31.3
Sample C Male 44.0
Sample D Male 36.2
Cingulate cortex
nTPM: 37.3
Samples: 4

Max nTPM: 40.9
Min nTPM: 32.6
Sample A Female 40.3
Sample B Female 32.6
Sample C Male 40.9
Sample D Male 35.5
Insular cortex
nTPM: 34.6
Samples: 4

Max nTPM: 40.8
Min nTPM: 29.3
Sample A Female 40.8
Sample B Female 29.3
Sample C Male 36.4
Sample D Male 31.9
Motor cortex
nTPM: 39.9
Samples: 4

Max nTPM: 44.9
Min nTPM: 34.9
Sample A Female 44.9
Sample B Female 41.5
Sample C Male 38.4
Sample D Male 34.9
Prefrontal cortex
nTPM: 40.6
Samples: 4

Max nTPM: 44.6
Min nTPM: 34.9
Sample A Female 42.5
Sample B Female 44.6
Sample C Male 40.4
Sample D Male 34.9
Somatosensory cortex
nTPM: 44.5
Samples: 3

Max nTPM: 49.1
Min nTPM: 41.9
Sample B Female 42.5
Sample C Male 41.9
Sample D Male 49.1
Temporal cortex
nTPM: 39.5
Samples: 4

Max nTPM: 45.3
Min nTPM: 34.5
Sample A Female 34.5
Sample B Female 43.7
Sample C Male 45.3
Sample D Male 34.5

CEREBRAL CORTEX - Mouse RNA-seqi
Max subtype nTPMi 117.0
Mouse sample Sample description nTPM
Occipital cortex
nTPM: 111.4
Samples: 4

Max nTPM: 118.8
Min nTPM: 100.2
Sample A Male 118.8
Sample B Male 100.2
Sample C Female 113.9
Sample D Female 112.5
Frontal cortex
nTPM: 107.5
Samples: 4

Max nTPM: 120.1
Min nTPM: 95.3
Sample A Male 95.3
Sample B Male 108.2
Sample C Female 120.1
Sample D Female 106.3
Retrosplenial and cingulate cortex
nTPM: 117.0
Samples: 4

Max nTPM: 122.4
Min nTPM: 103.2
Sample A Male 122.0
Sample B Male 120.5
Sample C Female 103.2
Sample D Female 122.4
Somatosensory cortex
nTPM: 107.0
Samples: 4

Max nTPM: 114.4
Min nTPM: 100.4
Sample A Male 112.3
Sample B Male 100.4
Sample C Female 114.4
Sample D Female 100.9

CEREBRAL CORTEX - Allen Mouse ISHi
Max subtype Expression energyi 15.5
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 15.5
2031 Antisense, RP_Baylor_102630, Mouse strain C57BL/6J (56 days, male) 15.5
2032 Antisense, RP_Baylor_102630, Mouse strain C57BL/6J (56 days, male) 10.3

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