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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:389.7 nTPM
HPA Brain:234.8 nTPM
GTEx:389.7 nTPM
FANTOM5:175.7 Scaled Tags Per Million
Pig:272.9 nTPM
Mouse:193.6 nTPM
Allen mouse:5.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

234.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 193.8
2411 Female, age 72, unknown 240.8
1870 Female, age 42, unknown 220.3
2019 Male, age 18, unknown 219.0
1827 Male, age 72, unknown 217.6
2828 Female, age 72, unknown 203.1
1833 Male, age 53, unknown 183.8
1830 Male, age 51, unknown 173.9
2666 Male, age 74, left hemisphere 166.0
2219 Male, age 76, both hemispheres 160.2
2586 Male, age 75, left hemisphere 153.1
Dorsal raphe nucleus
nTPM: 234.8
2298 Female, age 72, unknown 297.3
2016 Female, age 72, unknown 229.6
2047 Male, age 72, unknown 219.4
1828 Male, age 53, unknown 214.2
2750 Male, age 76, both hemispheres 213.7
Inferior colliculus
nTPM: 207.5
2097 Female, age 72, unknown 262.9
1890 Male, age 53, unknown 203.0
1848 Female, age 42, unknown 196.8
2849 Male, age 72, unknown 167.4
Median raphe nucleus
nTPM: 202.2
2220 Male, age 76, midline 202.2
Periaquaductal grey, anterior
nTPM: 214.6
2502 Female, age 75, unknown 226.4
1947 Male, age 18, unknown 219.3
1795 Male, age 51, unknown 198.1
Periaquaductal grey, dorsal
nTPM: 202.1
1840 Male, age 53, unknown 231.9
2464 Female, age 72, unknown 203.1
1831 Male, age 72, unknown 187.9
2850 Male, age 76, both hemispheres 185.5
Periaquaductal grey, lateral
nTPM: 192.2
2053 Male, age 18, unknown 215.5
2272 Male, age 74, both hemispheres 183.4
2140 Male, age 76, both hemispheres 177.8
Pretectal area
nTPM: 232.5
1816 Male, age 51, unknown 257.8
1944 Female, age 72, unknown 252.0
2667 Female, age 75, unknown 249.8
1817 Female, age 42, unknown 247.0
2273 Male, age 74, both hemispheres 245.6
2007 Male, age 72, unknown 241.8
1815 Male, age 53, unknown 239.7
2224 Female, age 72, unknown 225.2
2316 Male, age 76, right hemisphere 213.0
2407 Male, age 75, both hemispheres 193.4
2825 Male, age 18, unknown 192.0
Red nucleus
nTPM: 206.1
1821 Female, age 72, unknown 278.0
1954 Female, age 42, unknown 223.3
1904 Male, age 53, unknown 219.0
2823 Male, age 76, right hemisphere 216.5
2503 Female, age 72, unknown 214.2
1865 Male, age 51, unknown 211.7
2769 Male, age 72, unknown 205.7
2785 Male, age 18, unknown 199.9
2227 Male, age 72, unknown 199.3
2725 Female, age 75, unknown 186.7
2588 Male, age 74, left hemisphere 167.3
2584 Male, age 75, left hemisphere 151.8
Substantia nigra
nTPM: 215.5
2241 Male, age 72, unknown 276.6
1916 Female, age 42, unknown 246.3
1889 Female, age 72, unknown 239.2
1851 Male, age 51, unknown 237.3
2409 Female, age 72, unknown 228.4
1941 Male, age 53, unknown 202.3
2590 Female, age 75, unknown 190.8
2699 Male, age 18, unknown 186.4
2665 Male, age 74, both hemispheres 177.7
2583 Male, age 75, right hemisphere 169.9
Superior colliculus
nTPM: 210.5
2587 Male, age 74, left hemisphere 228.3
1895 Male, age 76, right hemisphere 227.5
2668 Female, age 75, unknown 224.4
2261 Male, age 18, unknown 224.0
2087 Female, age 72, unknown 213.7
1796 Male, age 53, unknown 208.5
1913 Female, age 42, unknown 206.3
1995 Male, age 72, unknown 192.2
1839 Male, age 51, unknown 190.6
2664 Male, age 75, both hemispheres 188.9
Ventral tegmental area
nTPM: 208.8
2410 Female, age 72, unknown 236.7
1915 Female, age 42, unknown 224.8
1942 Male, age 51, unknown 212.1
2021 Male, age 53, unknown 196.8
2218 Male, age 76, both hemispheres 193.7
2223 Female, age 72, unknown 188.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

389.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 389.7
Samples: 139

Max nTPM: 649.2
Min nTPM: 262.7
Std nTPM: 69.3
Median nTPM: 379.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 649.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 590.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 590.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 565.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 536.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 533.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 519.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 512.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 506.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 497.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 494.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 493.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 486.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 486.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 483.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 482.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 482.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 468.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 466.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 466.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 460.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 457.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 456.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 448.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 448.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 444.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 443.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 443.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 441.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 438.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 436.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 435.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 435.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 429.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 429.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 425.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 425.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 424.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 423.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 422.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 419.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 417.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 417.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 412.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 411.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 411.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 410.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 409.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 408.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 408.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 406.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 402.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 402.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 400.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 399.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 398.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 393.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 392.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 387.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 387.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 384.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 383.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 383.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 382.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 382.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 382.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 381.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 381.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 381.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 379.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 376.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 374.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 372.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 371.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 369.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 367.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 367.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 366.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 366.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 365.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 364.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 363.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 362.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 361.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 359.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 358.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 355.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 354.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 353.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 353.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 353.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 351.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 350.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 348.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 348.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 346.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 346.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 345.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 344.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 344.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 342.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 342.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 341.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 340.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 338.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 337.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 334.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 334.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 334.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 333.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 333.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 333.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 332.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 331.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 330.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 329.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 328.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 328.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 327.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 323.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 321.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 320.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 319.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 319.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 315.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 314.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 313.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 313.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 312.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 310.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 308.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 298.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 293.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 293.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 287.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 285.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 278.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 264.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 262.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

175.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 175.7
FF:10158-103A5 76 years, female 175.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

272.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 235.7
Samples: 4

Max nTPM: 322.1
Min nTPM: 185.4
Sample A Female 322.1
Sample B Female 185.4
Sample C Male 214.7
Sample D Male 220.6
Midbrain
nTPM: 273.0
Samples: 4

Max nTPM: 370.3
Min nTPM: 207.4
Sample A Female 370.3
Sample B Female 242.8
Sample C Male 271.4
Sample D Male 207.4
Periaqueductal gray
nTPM: 184.6
Samples: 3

Max nTPM: 191.4
Min nTPM: 178.3
Sample B Female 191.4
Sample C Male 184.2
Sample D Male 178.3
Superior colliculi
nTPM: 257.7
Samples: 4

Max nTPM: 311.6
Min nTPM: 187.6
Sample A Female 291.1
Sample B Female 187.6
Sample C Male 311.6
Sample D Male 240.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

193.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 193.6
Samples: 4

Max nTPM: 202.3
Min nTPM: 189.2
Sample A Male 202.3
Sample B Male 190.5
Sample C Female 192.4
Sample D Female 189.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

5.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.6
68637778 Antisense, RP_050126_01_F01, Mouse strain C57BL/6J (56 days, male) 5.6

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