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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:108.6 nTPM
HPA Brain:114.9 nTPM
GTEx:108.6 nTPM
FANTOM5:300.4 Scaled Tags Per Million
Pig:68.4 nTPM
Mouse:54.3 nTPM
Allen mouse:0.2 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

114.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 90.7
1870 Female, age 42, unknown 121.2
1830 Male, age 51, unknown 115.4
2411 Female, age 72, unknown 109.4
1833 Male, age 53, unknown 104.4
2019 Male, age 18, unknown 104.1
2828 Female, age 72, unknown 82.8
2666 Male, age 74, left hemisphere 75.6
2586 Male, age 75, left hemisphere 68.6
1827 Male, age 72, unknown 63.7
2219 Male, age 76, both hemispheres 62.2
Dorsal raphe nucleus
nTPM: 78.7
2750 Male, age 76, both hemispheres 109.6
2016 Female, age 72, unknown 84.4
1828 Male, age 53, unknown 74.2
2047 Male, age 72, unknown 65.3
2298 Female, age 72, unknown 59.7
Inferior colliculus
nTPM: 70.0
1848 Female, age 42, unknown 73.7
1890 Male, age 53, unknown 71.7
2097 Female, age 72, unknown 68.6
2849 Male, age 72, unknown 66.1
Median raphe nucleus
nTPM: 76.3
2220 Male, age 76, midline 76.3
Periaquaductal grey, anterior
nTPM: 66.4
2502 Female, age 75, unknown 79.7
1947 Male, age 18, unknown 66.0
1795 Male, age 51, unknown 53.5
Periaquaductal grey, dorsal
nTPM: 64.7
2464 Female, age 72, unknown 77.1
2850 Male, age 76, both hemispheres 66.6
1831 Male, age 72, unknown 64.7
1840 Male, age 53, unknown 50.2
Periaquaductal grey, lateral
nTPM: 66.5
2053 Male, age 18, unknown 68.1
2272 Male, age 74, both hemispheres 65.8
2140 Male, age 76, both hemispheres 65.7
Pretectal area
nTPM: 67.2
2316 Male, age 76, right hemisphere 83.8
1815 Male, age 53, unknown 83.5
1817 Female, age 42, unknown 74.2
2667 Female, age 75, unknown 68.2
2825 Male, age 18, unknown 66.8
2273 Male, age 74, both hemispheres 66.6
2407 Male, age 75, both hemispheres 64.9
2224 Female, age 72, unknown 64.4
2007 Male, age 72, unknown 63.7
1944 Female, age 72, unknown 54.8
1816 Male, age 51, unknown 47.8
Red nucleus
nTPM: 114.9
1865 Male, age 51, unknown 144.5
1904 Male, age 53, unknown 139.5
1821 Female, age 72, unknown 133.1
1954 Female, age 42, unknown 128.0
2227 Male, age 72, unknown 125.0
2769 Male, age 72, unknown 124.1
2785 Male, age 18, unknown 112.5
2503 Female, age 72, unknown 109.7
2823 Male, age 76, right hemisphere 107.0
2588 Male, age 74, left hemisphere 97.0
2725 Female, age 75, unknown 82.3
2584 Male, age 75, left hemisphere 76.0
Substantia nigra
nTPM: 78.6
2409 Female, age 72, unknown 91.5
1851 Male, age 51, unknown 88.3
2699 Male, age 18, unknown 86.9
2590 Female, age 75, unknown 82.0
2241 Male, age 72, unknown 80.1
1889 Female, age 72, unknown 77.2
2583 Male, age 75, right hemisphere 74.6
2665 Male, age 74, both hemispheres 72.1
1941 Male, age 53, unknown 67.7
1916 Female, age 42, unknown 65.9
Superior colliculus
nTPM: 79.9
1913 Female, age 42, unknown 120.0
1995 Male, age 72, unknown 110.2
2587 Male, age 74, left hemisphere 87.4
2668 Female, age 75, unknown 81.4
1839 Male, age 51, unknown 80.3
1895 Male, age 76, right hemisphere 76.2
1796 Male, age 53, unknown 65.4
2664 Male, age 75, both hemispheres 62.2
2087 Female, age 72, unknown 58.9
2261 Male, age 18, unknown 57.2
Ventral tegmental area
nTPM: 90.7
2223 Female, age 72, unknown 127.1
2410 Female, age 72, unknown 105.9
2021 Male, age 53, unknown 84.7
1942 Male, age 51, unknown 76.8
2218 Male, age 76, both hemispheres 75.6
1915 Female, age 42, unknown 74.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

108.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 108.6
Samples: 139

Max nTPM: 245.4
Min nTPM: 36.5
Std nTPM: 35.1
Median nTPM: 105.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 245.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 210.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 197.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 183.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 174.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 173.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 168.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 167.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 165.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 163.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 160.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 158.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 156.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 154.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 152.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 151.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 151.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 150.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 150.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 145.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 145.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 145.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 145.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 144.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 143.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 143.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 141.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 140.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 138.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 137.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 135.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 135.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 132.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 132.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 130.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 129.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 126.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 125.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 124.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 124.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 123.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 122.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 122.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 120.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 120.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 120.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 119.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 119.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 117.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 117.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 116.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 115.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 114.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 114.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 114.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 113.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 112.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 111.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 111.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 111.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 110.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 110.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 110.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 109.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 108.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 108.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 106.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 105.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 105.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 105.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 103.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 102.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 102.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 100.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 100.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 100.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 99.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 99.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 99.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 98.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 98.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 97.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 96.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 95.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 95.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 92.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 92.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 91.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 90.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 90.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 90.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 89.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 89.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 88.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 88.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 87.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 86.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 86.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 86.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 85.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 85.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 85.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 85.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 82.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 81.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 81.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 80.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 80.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 79.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 78.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 77.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 77.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 77.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 77.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 76.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 76.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 75.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 75.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 75.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 74.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 73.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 72.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 72.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 71.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 69.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 67.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 67.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 66.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 64.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 60.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 60.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 58.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 58.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 56.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 56.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 55.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 53.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 39.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 36.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

300.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 300.4
FF:10158-103A5 76 years, female 300.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

68.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 67.9
Samples: 4

Max nTPM: 83.1
Min nTPM: 51.7
Sample A Female 75.8
Sample B Female 61.0
Sample C Male 51.7
Sample D Male 83.1
Midbrain
nTPM: 68.4
Samples: 4

Max nTPM: 143.2
Min nTPM: 36.4
Sample A Female 143.2
Sample B Female 57.3
Sample C Male 36.8
Sample D Male 36.4
Periaqueductal gray
nTPM: 46.2
Samples: 3

Max nTPM: 51.1
Min nTPM: 40.6
Sample B Female 51.1
Sample C Male 40.6
Sample D Male 46.8
Superior colliculi
nTPM: 60.2
Samples: 4

Max nTPM: 73.8
Min nTPM: 48.5
Sample A Female 73.8
Sample B Female 61.4
Sample C Male 48.5
Sample D Male 57.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

54.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 54.3
Samples: 4

Max nTPM: 57.4
Min nTPM: 51.4
Sample A Male 55.5
Sample B Male 51.4
Sample C Female 53.0
Sample D Female 57.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.2
71378603 Antisense, RP_050517_02_A01, Mouse strain C57BL/6J (56 days, male) 0.2
70919812 Antisense, RP_050713_02_B02, Mouse strain C57BL/6J (56 days, male) 0.1

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