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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
70.5
nTPM
HPA:
39.7
nTPM
GTEx:
70.5
nTPM
FANTOM5:
263.9
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA016928
Cholangiocytes
Medium
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
39.7
Female, age 60
Liver sample 21 nTPM: 46.4
Male, age 54
Liver sample 23 nTPM: 34.2
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 49.3
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 46
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 41.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 31.6
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 32.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 47.3
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 37.5
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 30.8
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
70.5
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 70.5
Samples: 226
Max nTPM: 202.2
Min nTPM: 30.3
Std nTPM: 25.2
Median nTPM: 67.5
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
202.2
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
184.1
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
164.3
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
133.0
GTEX-REY6-1226-SM-48FDR
60-69 years, male
126.2
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
124.5
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
121.5
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
117.1
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
116.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
115.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
115.5
GTEX-QESD-2026-SM-447BI
20-29 years, male
114.7
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
114.0
GTEX-RU72-1426-SM-46MUF
50-59 years, female
113.6
GTEX-14JG1-1626-SM-664NH
40-49 years, male
110.7
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
108.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
108.0
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
106.9
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
106.7
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
105.1
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
103.0
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
101.6
GTEX-12696-0826-SM-5EGGE
60-69 years, male
101.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
101.0
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
99.4
GTEX-17F96-1226-SM-79OK2
70-79 years, male
98.9
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
98.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
98.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
97.6
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
96.0
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
95.4
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
94.6
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
94.4
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
94.4
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
93.3
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
92.8
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
92.7
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
92.5
GTEX-17HHE-0126-SM-79398
50-59 years, male
91.1
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
90.9
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
90.0
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
89.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
89.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
88.2
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
88.0
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
87.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
86.7
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
86.5
GTEX-R53T-0326-SM-48FEC
50-59 years, female
86.1
GTEX-13113-1326-SM-5GCOI
60-69 years, female
85.8
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
85.8
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
85.7
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
85.7
GTEX-RN64-1826-SM-48FDV
50-59 years, male
85.6
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
84.9
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
84.7
GTEX-14PHX-0526-SM-664NW
50-59 years, male
83.5
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
83.5
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
83.0
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
82.3
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
82.3
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
81.8
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
81.6
GTEX-11ZUS-2526-SM-59872
30-39 years, male
81.5
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
81.5
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
80.7
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
80.5
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
79.8
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
79.5
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
79.4
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
78.9
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
78.6
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
78.3
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
78.1
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
77.9
GTEX-14E7W-1526-SM-6871X
70-79 years, male
77.8
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
77.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
77.0
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
76.9
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
76.4
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
75.6
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
75.5
GTEX-18465-1626-SM-7LG6N
50-59 years, male
75.4
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
75.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
75.0
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
74.5
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
74.4
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
74.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
74.2
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
73.9
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
73.4
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
73.1
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
73.0
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
72.8
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
72.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
72.7
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
71.8
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
71.5
GTEX-S32W-1926-SM-4AD63
50-59 years, female
71.5
GTEX-P78B-1326-SM-3P611
40-49 years, female
71.3
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
71.2
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
70.6
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
70.3
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
70.2
GTEX-14PJO-1726-SM-68719
60-69 years, male
69.6
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
68.9
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
68.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
68.8
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
68.4
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
68.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
68.3
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
68.0
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
67.7
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
67.4
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
67.3
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
67.1
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
66.7
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
66.5
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
65.8
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
65.7
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
65.0
GTEX-S33H-1626-SM-4AD68
30-39 years, male
64.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
63.9
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
63.7
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
63.6
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
63.3
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
63.3
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
62.2
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
61.8
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
61.7
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
61.7
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
61.4
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
61.4
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
61.4
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
61.3
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
61.1
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
60.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
60.2
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
60.0
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
59.9
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
59.6
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
58.7
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
57.9
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
57.9
GTEX-18A66-2026-SM-7189C
60-69 years, male
57.8
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
57.1
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
57.0
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
56.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
56.5
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
55.9
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
55.9
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
55.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
55.3
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
54.9
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
54.7
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
54.4
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
54.3
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
54.3
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
53.8
GTEX-1399T-0826-SM-5IFES
60-69 years, male
53.7
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
53.4
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
53.4
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
52.9
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
52.7
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
52.7
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
52.7
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
52.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
52.6
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
52.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
52.1
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
52.0
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
51.7
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
51.5
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
51.4
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
50.9
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
50.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
50.7
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
50.6
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
50.5
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
49.5
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
49.5
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
49.5
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
48.5
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
48.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
48.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
48.1
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
48.1
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
47.9
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
47.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
47.3
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
47.3
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
47.2
GTEX-1B932-1426-SM-793AN
40-49 years, female
47.2
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
46.9
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
46.8
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
46.3
GTEX-11GSP-0626-SM-5986T
60-69 years, female
46.2
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
46.2
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
45.8
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
45.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
44.6
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
43.5
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
43.0
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
42.3
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
42.3
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
42.2
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
41.9
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
40.5
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
40.4
GTEX-1B933-1226-SM-731DW
50-59 years, female
40.3
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
40.3
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
40.2
GTEX-QEL4-1226-SM-447A4
50-59 years, male
40.2
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
40.0
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
39.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
39.8
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
38.2
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
38.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
36.7
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
35.6
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
35.5
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
34.9
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
34.4
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
33.5
GTEX-14XAO-0226-SM-68728
60-69 years, female
32.4
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
30.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
