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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:50.6 nTPM
HPA Brain:236.6 nTPM
GTEx:50.6 nTPM
FANTOM5:1.9 Scaled Tags Per Million
Pig:59.8 nTPM
Mouse:173.9 nTPM
Allen mouse:15.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

236.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 170.8
2666 Male, age 74, left hemisphere 516.0
2586 Male, age 75, left hemisphere 235.6
1827 Male, age 72, unknown 146.4
2219 Male, age 76, both hemispheres 145.5
2828 Female, age 72, unknown 126.9
2411 Female, age 72, unknown 118.4
1870 Female, age 42, unknown 113.0
2019 Male, age 18, unknown 112.3
1833 Male, age 53, unknown 99.1
1830 Male, age 51, unknown 94.7
Dorsal raphe nucleus
nTPM: 150.7
2047 Male, age 72, unknown 195.1
2298 Female, age 72, unknown 181.3
2750 Male, age 76, both hemispheres 151.0
1828 Male, age 53, unknown 135.2
2016 Female, age 72, unknown 91.1
Inferior colliculus
nTPM: 118.6
2097 Female, age 72, unknown 127.5
1848 Female, age 42, unknown 122.8
2849 Male, age 72, unknown 122.5
1890 Male, age 53, unknown 101.7
Median raphe nucleus
nTPM: 236.6
2220 Male, age 76, midline 236.6
Periaquaductal grey, anterior
nTPM: 139.0
1795 Male, age 51, unknown 173.7
1947 Male, age 18, unknown 130.0
2502 Female, age 75, unknown 113.3
Periaquaductal grey, dorsal
nTPM: 112.3
1840 Male, age 53, unknown 131.3
2850 Male, age 76, both hemispheres 113.6
1831 Male, age 72, unknown 103.1
2464 Female, age 72, unknown 101.3
Periaquaductal grey, lateral
nTPM: 85.4
2053 Male, age 18, unknown 97.6
2140 Male, age 76, both hemispheres 85.8
2272 Male, age 74, both hemispheres 72.9
Pretectal area
nTPM: 127.3
2007 Male, age 72, unknown 185.5
2224 Female, age 72, unknown 180.7
1817 Female, age 42, unknown 177.6
1816 Male, age 51, unknown 169.5
1944 Female, age 72, unknown 149.4
1815 Male, age 53, unknown 139.8
2825 Male, age 18, unknown 130.2
2667 Female, age 75, unknown 115.9
2316 Male, age 76, right hemisphere 61.7
2407 Male, age 75, both hemispheres 48.8
2273 Male, age 74, both hemispheres 41.5
Red nucleus
nTPM: 88.4
2584 Male, age 75, left hemisphere 233.4
2785 Male, age 18, unknown 111.8
1954 Female, age 42, unknown 101.0
2769 Male, age 72, unknown 83.1
1821 Female, age 72, unknown 81.0
2227 Male, age 72, unknown 79.7
2588 Male, age 74, left hemisphere 74.9
1904 Male, age 53, unknown 71.7
1865 Male, age 51, unknown 66.2
2823 Male, age 76, right hemisphere 65.1
2503 Female, age 72, unknown 62.7
2725 Female, age 75, unknown 30.8
Substantia nigra
nTPM: 142.0
1916 Female, age 42, unknown 227.6
2583 Male, age 75, right hemisphere 197.9
2665 Male, age 74, both hemispheres 172.1
1889 Female, age 72, unknown 165.0
1851 Male, age 51, unknown 149.5
1941 Male, age 53, unknown 141.5
2241 Male, age 72, unknown 121.0
2409 Female, age 72, unknown 107.8
2699 Male, age 18, unknown 93.8
2590 Female, age 75, unknown 43.4
Superior colliculus
nTPM: 194.9
2668 Female, age 75, unknown 1063.0
1796 Male, age 53, unknown 148.5
2087 Female, age 72, unknown 138.7
2261 Male, age 18, unknown 123.3
1839 Male, age 51, unknown 118.0
1895 Male, age 76, right hemisphere 87.8
2664 Male, age 75, both hemispheres 75.1
2587 Male, age 74, left hemisphere 72.5
1913 Female, age 42, unknown 63.7
1995 Male, age 72, unknown 58.8
Ventral tegmental area
nTPM: 149.8
1915 Female, age 42, unknown 169.1
2218 Male, age 76, both hemispheres 164.6
2410 Female, age 72, unknown 162.4
2021 Male, age 53, unknown 156.6
1942 Male, age 51, unknown 128.6
2223 Female, age 72, unknown 117.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

50.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 50.6
Samples: 139

Max nTPM: 141.0
Min nTPM: 0.7
Std nTPM: 37.3
Median nTPM: 42.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 141.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 137.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 136.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 135.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 134.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 134.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 133.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 132.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 116.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 115.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 110.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 106.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 103.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 101.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 100.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 100.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 99.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 98.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 97.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 97.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 96.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 94.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 93.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 92.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 90.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 89.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 85.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 85.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 84.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 83.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 78.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 75.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 74.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 74.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 73.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 73.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 72.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 72.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 71.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 69.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 69.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 68.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 68.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 66.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 66.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 65.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 65.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 63.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 62.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 62.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 60.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 59.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 59.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 59.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 58.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 57.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 57.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 57.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 54.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 52.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 52.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 52.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 50.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 50.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 49.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 47.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 45.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 44.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 42.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 42.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 42.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 41.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 41.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 40.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 39.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 38.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 38.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 37.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 37.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 37.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 36.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 33.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 33.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 33.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 32.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 31.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 29.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 29.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 28.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 28.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 27.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 27.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 26.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 26.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 25.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 25.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 24.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 24.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 22.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 22.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 21.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 20.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 19.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 18.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 18.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 18.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 17.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 17.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 15.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 15.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 12.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 12.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 11.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 10.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 10.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 10.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 10.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 9.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 9.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 9.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 9.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 8.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 8.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 8.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 7.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 7.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 6.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 5.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 5.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 4.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 4.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 4.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 4.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 3.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 0.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1.9
FF:10158-103A5 76 years, female 1.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

59.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 59.8
Samples: 4

Max nTPM: 88.8
Min nTPM: 30.7
Sample A Female 78.3
Sample B Female 41.4
Sample C Male 88.8
Sample D Male 30.7
Midbrain
nTPM: 54.8
Samples: 4

Max nTPM: 76.8
Min nTPM: 25.0
Sample A Female 25.0
Sample B Female 46.3
Sample C Male 71.2
Sample D Male 76.8
Periaqueductal gray
nTPM: 49.9
Samples: 3

Max nTPM: 66.7
Min nTPM: 41.2
Sample B Female 41.2
Sample C Male 66.7
Sample D Male 41.7
Superior colliculi
nTPM: 52.6
Samples: 4

Max nTPM: 66.4
Min nTPM: 30.2
Sample A Female 66.4
Sample B Female 30.2
Sample C Male 51.6
Sample D Male 62.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

173.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 173.9
Samples: 4

Max nTPM: 179.3
Min nTPM: 167.6
Sample A Male 179.3
Sample B Male 175.7
Sample C Female 167.6
Sample D Female 173.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

15.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.4
71381133 Antisense, RP_050510_03_F10, Mouse strain C57BL/6J (56 days, male) 15.4

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