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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
45.1
nTPM
HPA:
19.3
nTPM
GTEx:
45.1
nTPM
FANTOM5:
37.0
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA021771
Cholangiocytes
Low
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
19.3
Female, age 60
Liver sample 21 nTPM: 34.2
Male, age 54
Liver sample 23 nTPM: 22.7
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 14.9
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 9
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 26.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 30.7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 24.2
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 19.1
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 10
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 1.5
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
45.1
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 45.1
Samples: 226
Max nTPM: 173.0
Min nTPM: 0.1
Std nTPM: 36.1
Median nTPM: 38.1
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
173.0
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
151.8
GTEX-REY6-1226-SM-48FDR
60-69 years, male
151.5
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
151.4
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
125.0
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
123.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
123.5
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
123.0
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
120.0
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
119.0
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
117.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
113.9
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
110.1
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
106.8
GTEX-14PJO-1726-SM-68719
60-69 years, male
105.6
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
105.4
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
104.7
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
100.7
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
100.3
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
100.0
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
96.7
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
96.3
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
94.8
GTEX-P78B-1326-SM-3P611
40-49 years, female
94.6
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
94.6
GTEX-S32W-1926-SM-4AD63
50-59 years, female
93.6
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
92.1
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
91.7
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
90.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
89.8
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
89.8
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
88.5
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
87.1
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
85.7
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
84.9
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
83.1
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
82.6
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
82.3
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
80.6
GTEX-12696-0826-SM-5EGGE
60-69 years, male
80.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
79.9
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
79.5
GTEX-S33H-1626-SM-4AD68
30-39 years, male
78.2
GTEX-13113-1326-SM-5GCOI
60-69 years, female
76.4
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
76.4
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
73.5
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
73.4
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
73.3
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
71.7
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
71.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
70.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
69.5
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
69.3
GTEX-1B932-1426-SM-793AN
40-49 years, female
69.0
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
68.3
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
68.0
GTEX-X261-1726-SM-4PQYT
50-59 years, male
67.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
66.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
66.3
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
66.2
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
64.9
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
64.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
64.8
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
64.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
64.3
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
63.8
GTEX-QEL4-1226-SM-447A4
50-59 years, male
63.7
GTEX-Q734-0326-SM-48U15
40-49 years, female
63.5
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
63.1
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
62.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
61.6
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
59.9
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
58.9
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
58.8
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
58.2
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
57.9
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
57.6
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
57.3
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
55.9
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
55.8
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
55.3
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
54.7
GTEX-RU72-1426-SM-46MUF
50-59 years, female
54.6
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
54.2
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
53.4
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
53.1
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
52.5
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
52.5
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
51.3
GTEX-R53T-0326-SM-48FEC
50-59 years, female
51.1
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
50.0
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
49.8
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
49.3
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
48.9
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
47.0
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
46.9
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
46.8
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
46.5
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
46.2
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
44.7
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
44.3
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
44.1
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
43.2
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
42.6
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
42.2
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
41.5
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
41.2
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
41.1
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
40.6
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
39.8
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
39.4
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
38.6
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
38.4
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
37.9
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
36.6
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
36.5
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
36.0
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
35.1
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
34.1
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
33.9
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
33.6
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
33.3
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
33.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
32.9
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
32.8
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
32.7
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
32.5
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
32.4
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
32.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
31.4
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
31.0
GTEX-1399T-0826-SM-5IFES
60-69 years, male
30.3
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
30.2
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
30.1
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
30.0
GTEX-YECK-1926-SM-4W21H
60-69 years, male
29.3
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
29.0
GTEX-14PHX-0526-SM-664NW
50-59 years, male
27.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
26.2
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
25.6
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
25.4
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
25.2
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
24.9
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
24.7
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
24.6
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
23.9
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
23.3
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
23.2
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
22.0
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
20.7
GTEX-17HHE-0126-SM-79398
50-59 years, male
20.7
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
20.7
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
20.1
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
20.1
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
19.5
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
19.1
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
18.4
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
18.0
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
18.0
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
16.4
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
15.8
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
15.6
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
15.5
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
15.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
14.2
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
13.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
13.5
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
13.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
13.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
13.1
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
12.5
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
12.4
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
12.3
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
12.3
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
12.1
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
11.2
GTEX-17F96-1226-SM-79OK2
70-79 years, male
11.2
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
10.5
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
10.5
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
9.7
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
9.4
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
8.8
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
7.9
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
7.8
GTEX-QESD-2026-SM-447BI
20-29 years, male
7.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
7.7
GTEX-18465-1626-SM-7LG6N
50-59 years, male
7.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
7.5
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
7.3
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
7.2
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
7.1
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
6.9
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
6.8
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
6.8
GTEX-18A7A-1526-SM-72D69
50-59 years, female
6.6
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
6.6
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
6.5
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
6.3
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
6.1
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
6.0
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
6.0
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
6.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
5.7
GTEX-1B933-1226-SM-731DW
50-59 years, female
5.6
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
5.5
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
5.1
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
5.0
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
4.8
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
4.5
GTEX-RN64-1826-SM-48FDV
50-59 years, male
3.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
3.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
3.7
GTEX-14E7W-1526-SM-6871X
70-79 years, male
3.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
3.0
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
3.0
GTEX-14JG1-1626-SM-664NH
40-49 years, male
2.8
GTEX-11ZUS-2526-SM-59872
30-39 years, male
2.5
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
2.0
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
1.8
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
1.6
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
1.4
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
1.0
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
0.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
0.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
0.5
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
0.1
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
