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GYG2
HPA
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  • SUMMARY

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  • GYG2
PROTEIN SUMMARY GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

GYG2
Synonyms GN-2
Gene descriptioni

Full gene name according to HGNC.

Glycogenin 2
Protein classi

Assigned HPA protein class(es) for the encoded protein(s).

Enzymes
Metabolic proteins
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome X
Cytoband p22.33
Chromosome location (bp) 2828822 - 2882820
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

6
Ensembl ENSG00000056998 (version 109)
Entrez gene 8908
HGNC HGNC:4700
UniProt O15488 (UniProt - Evidence at protein level)
neXtProt NX_O15488
GeneCards GYG2
Antibodypedia GYG2 antibodies


PROTEIN FUNCTION
Protein function (UniProt)i

Useful information about the protein provided by UniProt.

Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase.... show less
Molecular function (UniProt)i

Keywords assigned by UniProt to proteins due to their particular molecular function.

Transferase
Biological process (UniProt)i

Keywords assigned by UniProt to proteins because they are involved in a particular biological process.

Glycogen biosynthesis
Ligand (UniProt)i

Keywords assigned by UniProt to proteins because they bind, are associated with, or whose activity is dependent of some molecule.

Manganese, Metal-binding
Gene summary (Entrez)i

Useful information about the gene from Entrez

This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
GYG2-201
ENSP00000487294
ENST00000353656
O15488
[Direct mapping] Glycogenin-2
Show all
Enzymes
   ENZYME proteins
   Transferases
Metabolic proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005978 [glycogen biosynthetic process]
GO:0008194 [UDP-glycosyltransferase activity]
GO:0008466 [glycogenin glucosyltransferase activity]
GO:0016740 [transferase activity]
GO:0016757 [glycosyltransferase activity]
GO:0034645 [cellular macromolecule biosynthetic process]
GO:0044238 [primary metabolic process]
GO:0046872 [metal ion binding]
GO:0102751 [UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity]
Show all
430 aa
47.5 kDa
No 0
GYG2-202
ENSP00000370549
ENST00000381157
J3QSZ3
[Direct mapping] Glycogenin-2
Show all
Metabolic proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008194 [UDP-glycosyltransferase activity]
GO:0016757 [glycosyltransferase activity]
GO:0034645 [cellular macromolecule biosynthetic process]
GO:0044238 [primary metabolic process]
Show all
244 aa
26.2 kDa
No 0
GYG2-204
ENSP00000370555
ENST00000381163
O15488
[Direct mapping] Glycogenin-2
Show all
Enzymes
   ENZYME proteins
   Transferases
Metabolic proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005978 [glycogen biosynthetic process]
GO:0008194 [UDP-glycosyltransferase activity]
GO:0008466 [glycogenin glucosyltransferase activity]
GO:0016740 [transferase activity]
GO:0016757 [glycosyltransferase activity]
GO:0034645 [cellular macromolecule biosynthetic process]
GO:0044238 [primary metabolic process]
GO:0046872 [metal ion binding]
GO:0102751 [UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity]
Show all
501 aa
55.2 kDa
No 0
GYG2-205
ENSP00000381786
ENST00000398806
O15488
[Direct mapping] Glycogenin-2
Show all
Enzymes
   ENZYME proteins
   Transferases
Metabolic proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005978 [glycogen biosynthetic process]
GO:0008194 [UDP-glycosyltransferase activity]
GO:0008466 [glycogenin glucosyltransferase activity]
GO:0016740 [transferase activity]
GO:0016757 [glycosyltransferase activity]
GO:0034645 [cellular macromolecule biosynthetic process]
GO:0044238 [primary metabolic process]
GO:0046872 [metal ion binding]
GO:0102751 [UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity]
Show all
470 aa
52 kDa
No 0
GYG2-208
ENSP00000430764
ENST00000520904
E5RIC9
[Direct mapping] Glycogenin-2
Show all
Metabolic proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008194 [UDP-glycosyltransferase activity]
GO:0016757 [glycosyltransferase activity]
GO:0034645 [cellular macromolecule biosynthetic process]
GO:0044238 [primary metabolic process]
Show all
137 aa
15.4 kDa
No 0
GYG2-209
ENSP00000491962
ENST00000639373
A0A1W2PQ75
[Direct mapping] Glycogenin-2
Show all
Metabolic proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008194 [UDP-glycosyltransferase activity]
GO:0016757 [glycosyltransferase activity]
GO:0034645 [cellular macromolecule biosynthetic process]
GO:0044238 [primary metabolic process]
Show all
430 aa
47.6 kDa
No 0

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