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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:51.9 nTPM
HPA Brain:59.5 nTPM
GTEx:51.9 nTPM
FANTOM5:110.3 Scaled Tags Per Million
Pig:90.1 nTPM
Mouse:67.0 nTPM
Allen mouse:0.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

59.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 54.4
1870 Female, age 42, unknown 59.7
1827 Male, age 72, unknown 59.5
2019 Male, age 18, unknown 58.3
2411 Female, age 72, unknown 57.1
1830 Male, age 51, unknown 54.7
1833 Male, age 53, unknown 54.7
2666 Male, age 74, left hemisphere 51.4
2828 Female, age 72, unknown 51.3
2219 Male, age 76, both hemispheres 49.0
2586 Male, age 75, left hemisphere 48.7
Dorsal raphe nucleus
nTPM: 54.4
2016 Female, age 72, unknown 62.6
2298 Female, age 72, unknown 54.7
1828 Male, age 53, unknown 54.2
2750 Male, age 76, both hemispheres 53.4
2047 Male, age 72, unknown 47.2
Inferior colliculus
nTPM: 56.0
1848 Female, age 42, unknown 58.0
2849 Male, age 72, unknown 56.3
2097 Female, age 72, unknown 56.0
1890 Male, age 53, unknown 53.9
Median raphe nucleus
nTPM: 46.7
2220 Male, age 76, midline 46.7
Periaquaductal grey, anterior
nTPM: 54.4
1947 Male, age 18, unknown 57.6
2502 Female, age 75, unknown 56.1
1795 Male, age 51, unknown 49.6
Periaquaductal grey, dorsal
nTPM: 58.6
1840 Male, age 53, unknown 64.1
2850 Male, age 76, both hemispheres 58.5
1831 Male, age 72, unknown 57.7
2464 Female, age 72, unknown 54.2
Periaquaductal grey, lateral
nTPM: 55.4
2140 Male, age 76, both hemispheres 57.5
2053 Male, age 18, unknown 57.3
2272 Male, age 74, both hemispheres 51.4
Pretectal area
nTPM: 55.8
2007 Male, age 72, unknown 61.2
1815 Male, age 53, unknown 60.6
1817 Female, age 42, unknown 60.5
1816 Male, age 51, unknown 56.3
2825 Male, age 18, unknown 56.3
1944 Female, age 72, unknown 55.7
2224 Female, age 72, unknown 54.8
2316 Male, age 76, right hemisphere 54.4
2273 Male, age 74, both hemispheres 53.4
2407 Male, age 75, both hemispheres 51.8
2667 Female, age 75, unknown 48.7
Red nucleus
nTPM: 59.5
2503 Female, age 72, unknown 69.0
1821 Female, age 72, unknown 64.8
1865 Male, age 51, unknown 63.5
2725 Female, age 75, unknown 63.4
1954 Female, age 42, unknown 61.4
2588 Male, age 74, left hemisphere 60.0
2823 Male, age 76, right hemisphere 57.5
1904 Male, age 53, unknown 55.5
2769 Male, age 72, unknown 55.1
2785 Male, age 18, unknown 55.0
2584 Male, age 75, left hemisphere 54.2
2227 Male, age 72, unknown 54.1
Substantia nigra
nTPM: 52.9
1889 Female, age 72, unknown 58.8
2583 Male, age 75, right hemisphere 55.4
2590 Female, age 75, unknown 55.2
2241 Male, age 72, unknown 54.8
2409 Female, age 72, unknown 52.3
2665 Male, age 74, both hemispheres 52.2
1941 Male, age 53, unknown 51.7
2699 Male, age 18, unknown 51.7
1851 Male, age 51, unknown 51.0
1916 Female, age 42, unknown 46.4
Superior colliculus
nTPM: 56.6
1995 Male, age 72, unknown 61.7
1895 Male, age 76, right hemisphere 61.3
1913 Female, age 42, unknown 60.4
2587 Male, age 74, left hemisphere 60.2
1839 Male, age 51, unknown 58.4
2668 Female, age 75, unknown 55.8
1796 Male, age 53, unknown 53.5
2664 Male, age 75, both hemispheres 52.7
2261 Male, age 18, unknown 52.2
2087 Female, age 72, unknown 50.2
Ventral tegmental area
nTPM: 49.5
2410 Female, age 72, unknown 52.1
2223 Female, age 72, unknown 50.5
1915 Female, age 42, unknown 50.2
1942 Male, age 51, unknown 49.8
2021 Male, age 53, unknown 49.4
2218 Male, age 76, both hemispheres 44.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

51.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 51.9
Samples: 139

Max nTPM: 116.2
Min nTPM: 31.9
Std nTPM: 14.4
Median nTPM: 47.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 116.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 103.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 93.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 90.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 88.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 85.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 83.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 82.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 82.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 79.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 78.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 77.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 73.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 71.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 70.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 67.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 66.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 65.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 63.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 63.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 63.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 62.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 62.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 61.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 61.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 61.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 60.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 59.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 59.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 59.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 58.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 58.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 57.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 57.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 57.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 57.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 56.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 56.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 56.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 55.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 55.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 55.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 54.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 54.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 54.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 53.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 52.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 52.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 52.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 52.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 52.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 51.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 50.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 50.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 50.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 50.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 50.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 50.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 50.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 50.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 49.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 49.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 49.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 48.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 48.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 48.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 48.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 48.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 48.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 47.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 47.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 47.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 47.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 47.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 47.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 47.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 47.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 47.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 47.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 47.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 47.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 46.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 46.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 46.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 45.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 45.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 45.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 45.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 45.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 45.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 45.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 44.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 44.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 44.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 44.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 44.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 43.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 43.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 42.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 42.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 42.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 42.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 42.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 42.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 41.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 41.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 41.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 41.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 41.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 41.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 41.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 41.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 40.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 40.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 40.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 40.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 40.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 40.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 40.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 40.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 38.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 38.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 38.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 38.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 38.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 38.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 38.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 37.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 37.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 37.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 36.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 36.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 35.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 35.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 35.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 34.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 34.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 33.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 31.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

110.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 110.3
FF:10158-103A5 76 years, female 110.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

90.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 76.8
Samples: 4

Max nTPM: 88.6
Min nTPM: 68.7
Sample A Female 88.6
Sample B Female 68.7
Sample C Male 74.1
Sample D Male 75.9
Midbrain
nTPM: 90.1
Samples: 4

Max nTPM: 103.7
Min nTPM: 85.1
Sample A Female 103.7
Sample B Female 85.2
Sample C Male 86.2
Sample D Male 85.1
Periaqueductal gray
nTPM: 77.0
Samples: 3

Max nTPM: 79.3
Min nTPM: 72.4
Sample B Female 72.4
Sample C Male 79.3
Sample D Male 79.3
Superior colliculi
nTPM: 86.1
Samples: 4

Max nTPM: 94.9
Min nTPM: 71.9
Sample A Female 94.9
Sample B Female 71.9
Sample C Male 88.6
Sample D Male 88.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

67.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 67.0
Samples: 4

Max nTPM: 72.7
Min nTPM: 61.6
Sample A Male 61.6
Sample B Male 69.5
Sample C Female 72.7
Sample D Female 64.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.6
532735 Antisense, RP_040825_01_H09, Mouse strain C57BL/6J (56 days, male) 0.6

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