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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:121.3 nTPM
HPA Brain:72.8 nTPM
GTEx:121.3 nTPM
FANTOM5:71.0 Scaled Tags Per Million
Pig:104.2 nTPM
Mouse:31.0 nTPM
Allen mouse:7.4 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

72.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 62.3
2219 Male, age 76, both hemispheres 95.8
2666 Male, age 74, left hemisphere 91.9
1827 Male, age 72, unknown 68.2
2586 Male, age 75, left hemisphere 64.9
2828 Female, age 72, unknown 63.2
2019 Male, age 18, unknown 56.7
1833 Male, age 53, unknown 51.3
1830 Male, age 51, unknown 48.9
1870 Female, age 42, unknown 45.2
2411 Female, age 72, unknown 36.8
Dorsal raphe nucleus
nTPM: 30.3
1828 Male, age 53, unknown 36.8
2016 Female, age 72, unknown 31.8
2298 Female, age 72, unknown 28.6
2047 Male, age 72, unknown 27.4
2750 Male, age 76, both hemispheres 27.0
Inferior colliculus
nTPM: 72.8
2097 Female, age 72, unknown 81.0
2849 Male, age 72, unknown 76.5
1848 Female, age 42, unknown 68.1
1890 Male, age 53, unknown 65.6
Median raphe nucleus
nTPM: 27.3
2220 Male, age 76, midline 27.3
Periaquaductal grey, anterior
nTPM: 56.9
2502 Female, age 75, unknown 63.3
1795 Male, age 51, unknown 59.0
1947 Male, age 18, unknown 48.2
Periaquaductal grey, dorsal
nTPM: 45.6
2464 Female, age 72, unknown 51.8
1831 Male, age 72, unknown 51.5
1840 Male, age 53, unknown 46.2
2850 Male, age 76, both hemispheres 32.9
Periaquaductal grey, lateral
nTPM: 39.8
2053 Male, age 18, unknown 49.3
2140 Male, age 76, both hemispheres 35.8
2272 Male, age 74, both hemispheres 34.4
Pretectal area
nTPM: 61.2
1816 Male, age 51, unknown 95.0
1817 Female, age 42, unknown 85.4
2007 Male, age 72, unknown 84.3
1944 Female, age 72, unknown 79.3
1815 Male, age 53, unknown 71.8
2316 Male, age 76, right hemisphere 55.8
2825 Male, age 18, unknown 46.3
2667 Female, age 75, unknown 45.5
2407 Male, age 75, both hemispheres 39.8
2224 Female, age 72, unknown 35.5
2273 Male, age 74, both hemispheres 34.4
Red nucleus
nTPM: 60.7
2588 Male, age 74, left hemisphere 88.6
2725 Female, age 75, unknown 82.2
2785 Male, age 18, unknown 68.0
2503 Female, age 72, unknown 65.9
2584 Male, age 75, left hemisphere 64.8
2227 Male, age 72, unknown 53.9
1865 Male, age 51, unknown 52.6
1954 Female, age 42, unknown 52.3
1904 Male, age 53, unknown 51.9
2823 Male, age 76, right hemisphere 50.8
2769 Male, age 72, unknown 50.5
1821 Female, age 72, unknown 46.6
Substantia nigra
nTPM: 52.7
2665 Male, age 74, both hemispheres 72.9
1889 Female, age 72, unknown 66.0
1851 Male, age 51, unknown 59.7
2699 Male, age 18, unknown 51.1
2409 Female, age 72, unknown 50.9
1941 Male, age 53, unknown 50.4
2590 Female, age 75, unknown 47.0
2583 Male, age 75, right hemisphere 46.7
1916 Female, age 42, unknown 45.4
2241 Male, age 72, unknown 36.9
Superior colliculus
nTPM: 64.2
1796 Male, age 53, unknown 83.8
2087 Female, age 72, unknown 73.8
2261 Male, age 18, unknown 68.9
1895 Male, age 76, right hemisphere 64.8
1995 Male, age 72, unknown 62.7
1913 Female, age 42, unknown 59.7
2664 Male, age 75, both hemispheres 57.6
1839 Male, age 51, unknown 57.3
2668 Female, age 75, unknown 57.0
2587 Male, age 74, left hemisphere 55.9
Ventral tegmental area
nTPM: 53.1
2223 Female, age 72, unknown 94.0
1915 Female, age 42, unknown 51.3
2410 Female, age 72, unknown 49.6
2218 Male, age 76, both hemispheres 48.0
1942 Male, age 51, unknown 38.8
2021 Male, age 53, unknown 37.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

121.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 121.3
Samples: 139

Max nTPM: 355.0
Min nTPM: 28.9
Std nTPM: 66.5
Median nTPM: 104.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 355.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 333.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 324.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 307.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 304.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 293.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 276.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 260.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 260.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 256.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 238.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 227.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 225.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 210.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 200.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 200.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 196.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 192.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 188.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 188.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 182.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 182.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 181.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 181.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 176.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 176.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 175.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 171.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 166.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 165.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 165.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 154.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 153.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 152.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 150.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 150.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 149.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 143.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 140.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 134.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 134.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 132.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 130.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 129.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 129.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 128.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 126.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 123.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 118.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 116.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 114.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 112.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 112.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 112.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 112.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 111.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 111.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 110.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 108.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 108.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 107.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 106.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 106.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 106.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 105.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 105.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 105.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 105.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 105.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 104.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 104.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 102.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 101.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 98.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 98.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 97.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 96.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 96.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 96.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 96.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 96.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 95.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 93.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 93.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 93.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 92.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 92.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 89.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 89.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 86.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 84.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 84.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 83.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 82.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 82.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 82.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 80.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 80.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 80.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 78.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 78.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 77.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 77.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 76.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 76.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 75.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 75.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 74.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 74.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 70.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 70.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 69.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 69.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 68.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 68.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 66.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 66.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 65.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 64.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 64.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 64.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 63.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 61.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 59.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 59.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 56.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 56.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 55.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 52.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 51.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 51.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 48.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 47.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 46.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 46.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 41.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 39.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 31.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 28.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

71.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 71.0
FF:10158-103A5 76 years, female 71.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

104.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 71.9
Samples: 4

Max nTPM: 81.5
Min nTPM: 59.2
Sample A Female 76.7
Sample B Female 70.2
Sample C Male 81.5
Sample D Male 59.2
Midbrain
nTPM: 80.5
Samples: 4

Max nTPM: 111.9
Min nTPM: 39.1
Sample A Female 39.1
Sample B Female 61.8
Sample C Male 109.0
Sample D Male 111.9
Periaqueductal gray
nTPM: 38.3
Samples: 3

Max nTPM: 41.4
Min nTPM: 34.9
Sample B Female 38.5
Sample C Male 41.4
Sample D Male 34.9
Superior colliculi
nTPM: 104.3
Samples: 4

Max nTPM: 120.6
Min nTPM: 78.7
Sample A Female 116.3
Sample B Female 78.7
Sample C Male 120.6
Sample D Male 101.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

31.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 31.1
Samples: 4

Max nTPM: 33.8
Min nTPM: 27.9
Sample A Male 33.8
Sample B Male 27.9
Sample C Female 30.1
Sample D Female 32.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.4
68797501 Antisense, RP_050125_02_E12, Mouse strain C57BL/6J (56 days, male) 7.4

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