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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
93.3
nTPM
HPA:
93.3
nTPM
GTEx:
89.2
nTPM
FANTOM5:
212.2
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA031068
Antibody HPA072487
Antibody CAB024930
Cholangiocytes
Not detected
High
Medium
Hepatocytes
Medium
High
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
93.3
Female, age 60
Liver sample 21 nTPM: 101.8
Male, age 54
Liver sample 23 nTPM: 89.4
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 93.8
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 64.5
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 84
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 105.9
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 95.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 94.8
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 71.6
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 132
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
89.2
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 89.2
Samples: 226
Max nTPM: 294.8
Min nTPM: 27.2
Std nTPM: 44.6
Median nTPM: 77.1
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
294.8
GTEX-Q734-0326-SM-48U15
40-49 years, female
248.9
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
218.1
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
208.1
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
202.0
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
201.4
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
195.2
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
194.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
190.6
GTEX-1B932-1426-SM-793AN
40-49 years, female
190.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
187.6
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
187.2
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
178.2
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
172.7
GTEX-14PHX-0526-SM-664NW
50-59 years, male
171.2
GTEX-QEL4-1226-SM-447A4
50-59 years, male
164.3
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
162.7
GTEX-14XAO-0226-SM-68728
60-69 years, female
160.4
GTEX-S32W-1926-SM-4AD63
50-59 years, female
156.6
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
155.9
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
155.0
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
154.4
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
150.6
GTEX-R53T-0326-SM-48FEC
50-59 years, female
149.3
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
147.3
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
145.9
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
142.5
GTEX-13113-1326-SM-5GCOI
60-69 years, female
141.4
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
141.2
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
141.0
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
138.2
GTEX-18A66-2026-SM-7189C
60-69 years, male
136.3
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
136.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
135.7
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
133.4
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
133.0
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
132.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
131.6
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
129.5
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
128.7
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
128.4
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
124.9
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
122.9
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
121.5
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
121.3
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
121.2
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
121.0
GTEX-17HHE-0126-SM-79398
50-59 years, male
119.9
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
118.5
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
118.1
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
117.3
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
117.1
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
115.4
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
114.6
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
114.5
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
113.7
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
113.6
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
112.3
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
111.9
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
110.5
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
110.1
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
109.2
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
108.7
GTEX-P78B-1326-SM-3P611
40-49 years, female
106.4
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
106.2
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
105.9
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
105.4
GTEX-O5YV-0726-SM-EV798
60-69 years, female
105.2
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
103.5
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
103.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
103.0
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
102.2
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
100.6
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
100.4
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
100.3
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
99.1
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
98.8
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
98.1
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
97.9
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
96.8
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
95.6
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
95.1
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
95.0
GTEX-14JG1-1626-SM-664NH
40-49 years, male
94.9
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
94.9
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
93.6
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
93.1
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
93.0
GTEX-S33H-1626-SM-4AD68
30-39 years, male
89.0
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
88.4
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
87.8
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
87.6
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
86.6
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
86.2
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
85.9
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
85.1
GTEX-18A7A-1526-SM-72D69
50-59 years, female
85.0
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
84.5
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
83.9
GTEX-REY6-1226-SM-48FDR
60-69 years, male
83.8
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
83.3
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
83.1
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
82.9
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
81.7
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
81.7
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
81.3
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
80.3
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
80.2
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
79.9
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
79.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
78.9
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
78.7
GTEX-14E7W-1526-SM-6871X
70-79 years, male
77.3
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
77.0
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
76.7
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
76.6
GTEX-11GSP-0626-SM-5986T
60-69 years, female
76.1
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
76.0
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
74.8
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
74.2
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
74.2
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
74.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
73.8
GTEX-QESD-2026-SM-447BI
20-29 years, male
73.3
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
72.7
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
72.5
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
72.2
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
70.4
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
70.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
68.8
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
68.7
GTEX-RU72-1426-SM-46MUF
50-59 years, female
68.1
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
67.1
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
67.0
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
67.0
GTEX-1399T-0826-SM-5IFES
60-69 years, male
66.4
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
65.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
64.1
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
63.8
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
63.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
63.1
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
62.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
62.3
GTEX-18465-1626-SM-7LG6N
50-59 years, male
62.2
GTEX-12696-0826-SM-5EGGE
60-69 years, male
62.1
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
62.1
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
61.7
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
61.0
GTEX-1B933-1226-SM-731DW
50-59 years, female
60.5
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
59.9
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
58.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
58.9
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
58.6
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
58.6
GTEX-X261-1726-SM-4PQYT
50-59 years, male
58.5
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
58.3
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
58.1
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
57.1
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
56.9
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
56.7
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
56.6
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
56.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
56.4
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
56.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
56.3
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
56.3
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
55.9
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
55.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
55.8
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
55.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
54.4
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
54.2
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
53.9
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
53.9
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
53.3
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
53.3
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
53.1
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
52.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
52.8
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
52.2
GTEX-11ZUS-2526-SM-59872
30-39 years, male
51.9
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
51.7
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
51.6
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
50.9
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
50.8
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
50.8
GTEX-14PJO-1726-SM-68719
60-69 years, male
50.7
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
50.7
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
50.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
50.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
49.8
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
49.2
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
49.1
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
48.8
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
48.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
48.7
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
48.5
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
48.1
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
48.0
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
48.0
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
47.9
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
47.8
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
47.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
47.2
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
46.7
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
46.1
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
46.1
GTEX-RN64-1826-SM-48FDV
50-59 years, male
45.8
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
45.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
44.3
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
43.6
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
43.3
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
43.2
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
40.3
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
39.2
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
39.1
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
38.7
GTEX-13112-1426-SM-5EGH8
50-59 years, male
38.2
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
37.9
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
37.7
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
37.4
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
35.6
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
34.3
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
33.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
29.2
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
27.2
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
