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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:43.8 nTPM
HPA Brain:194.1 nTPM
GTEx:43.8 nTPM
FANTOM5:77.2 Scaled Tags Per Million
Pig:69.8 nTPM
Mouse:122.8 nTPM
Allen mouse:12.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

194.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 114.6
2586 Male, age 75, left hemisphere 148.3
2666 Male, age 74, left hemisphere 134.3
1827 Male, age 72, unknown 128.1
2828 Female, age 72, unknown 124.9
2411 Female, age 72, unknown 119.7
1870 Female, age 42, unknown 107.6
1833 Male, age 53, unknown 107.3
2019 Male, age 18, unknown 92.7
1830 Male, age 51, unknown 91.8
2219 Male, age 76, both hemispheres 91.8
Dorsal raphe nucleus
nTPM: 137.9
2047 Male, age 72, unknown 168.4
2298 Female, age 72, unknown 167.5
2750 Male, age 76, both hemispheres 128.0
1828 Male, age 53, unknown 125.9
2016 Female, age 72, unknown 99.9
Inferior colliculus
nTPM: 107.6
1848 Female, age 42, unknown 125.5
2849 Male, age 72, unknown 125.4
2097 Female, age 72, unknown 90.3
1890 Male, age 53, unknown 89.2
Median raphe nucleus
nTPM: 194.1
2220 Male, age 76, midline 194.1
Periaquaductal grey, anterior
nTPM: 136.7
1795 Male, age 51, unknown 155.4
1947 Male, age 18, unknown 149.5
2502 Female, age 75, unknown 105.1
Periaquaductal grey, dorsal
nTPM: 132.2
2850 Male, age 76, both hemispheres 153.6
1840 Male, age 53, unknown 149.9
2464 Female, age 72, unknown 120.0
1831 Male, age 72, unknown 105.1
Periaquaductal grey, lateral
nTPM: 146.5
2140 Male, age 76, both hemispheres 157.7
2272 Male, age 74, both hemispheres 144.8
2053 Male, age 18, unknown 137.0
Pretectal area
nTPM: 137.1
1944 Female, age 72, unknown 181.1
1816 Male, age 51, unknown 172.8
2007 Male, age 72, unknown 144.6
1815 Male, age 53, unknown 144.0
2273 Male, age 74, both hemispheres 139.8
2224 Female, age 72, unknown 137.5
2667 Female, age 75, unknown 132.7
2825 Male, age 18, unknown 126.4
1817 Female, age 42, unknown 124.1
2316 Male, age 76, right hemisphere 111.5
2407 Male, age 75, both hemispheres 94.0
Red nucleus
nTPM: 88.3
2725 Female, age 75, unknown 153.9
2584 Male, age 75, left hemisphere 114.7
2588 Male, age 74, left hemisphere 107.3
2785 Male, age 18, unknown 92.2
1821 Female, age 72, unknown 85.5
2823 Male, age 76, right hemisphere 79.2
2769 Male, age 72, unknown 77.3
2227 Male, age 72, unknown 75.1
2503 Female, age 72, unknown 73.1
1954 Female, age 42, unknown 69.2
1904 Male, age 53, unknown 66.6
1865 Male, age 51, unknown 65.3
Substantia nigra
nTPM: 123.7
1916 Female, age 42, unknown 155.5
1851 Male, age 51, unknown 143.2
1941 Male, age 53, unknown 135.7
2241 Male, age 72, unknown 130.8
1889 Female, age 72, unknown 127.9
2409 Female, age 72, unknown 124.5
2583 Male, age 75, right hemisphere 114.0
2699 Male, age 18, unknown 106.2
2665 Male, age 74, both hemispheres 100.5
2590 Female, age 75, unknown 98.6
Superior colliculus
nTPM: 113.3
2261 Male, age 18, unknown 148.8
2087 Female, age 72, unknown 146.7
1796 Male, age 53, unknown 144.3
2664 Male, age 75, both hemispheres 116.0
1839 Male, age 51, unknown 108.3
1895 Male, age 76, right hemisphere 102.0
2668 Female, age 75, unknown 99.8
1913 Female, age 42, unknown 94.8
1995 Male, age 72, unknown 91.0
2587 Male, age 74, left hemisphere 81.7
Ventral tegmental area
nTPM: 121.5
2218 Male, age 76, both hemispheres 137.6
1915 Female, age 42, unknown 135.3
2410 Female, age 72, unknown 124.7
2021 Male, age 53, unknown 118.4
1942 Male, age 51, unknown 115.3
2223 Female, age 72, unknown 97.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

43.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 43.8
Samples: 139

Max nTPM: 122.4
Min nTPM: 8.3
Std nTPM: 22.4
Median nTPM: 40.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 122.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 99.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 96.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 93.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 91.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 89.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 88.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 88.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 88.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 85.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 82.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 82.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 81.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 80.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 80.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 79.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 74.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 74.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 72.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 71.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 70.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 70.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 70.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 70.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 65.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 65.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 65.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 61.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 59.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 58.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 57.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 56.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 55.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 54.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 53.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 53.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 53.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 52.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 52.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 51.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 51.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 50.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 50.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 49.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 49.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 48.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 48.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 47.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 47.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 46.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 46.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 46.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 45.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 45.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 45.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 44.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 43.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 43.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 43.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 43.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 43.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 43.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 41.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 41.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 41.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 41.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 40.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 40.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 40.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 40.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 40.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 38.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 38.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 37.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 37.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 37.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 36.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 35.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 35.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 35.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 34.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 34.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 34.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 34.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 34.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 33.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 33.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 32.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 32.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 31.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 31.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 31.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 31.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 31.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 30.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 30.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 30.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 30.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 30.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 30.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 30.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 30.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 29.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 28.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 27.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 27.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 27.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 27.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 26.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 25.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 25.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 24.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 24.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 24.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 22.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 21.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 20.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 20.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 20.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 20.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 20.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 19.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 19.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 19.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 19.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 18.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 18.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 17.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 17.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 16.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 16.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 16.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 15.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 14.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 14.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 12.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 11.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 10.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 8.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

77.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 77.2
FF:10158-103A5 76 years, female 77.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

69.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 66.8
Samples: 4

Max nTPM: 91.4
Min nTPM: 39.9
Sample A Female 91.4
Sample B Female 49.0
Sample C Male 87.0
Sample D Male 39.9
Midbrain
nTPM: 69.8
Samples: 4

Max nTPM: 111.5
Min nTPM: 49.2
Sample A Female 49.2
Sample B Female 50.6
Sample C Male 111.5
Sample D Male 68.0
Periaqueductal gray
nTPM: 49.7
Samples: 3

Max nTPM: 62.2
Min nTPM: 38.7
Sample B Female 48.2
Sample C Male 62.2
Sample D Male 38.7
Superior colliculi
nTPM: 69.0
Samples: 4

Max nTPM: 98.2
Min nTPM: 42.0
Sample A Female 70.6
Sample B Female 42.0
Sample C Male 98.2
Sample D Male 65.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

122.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 122.9
Samples: 4

Max nTPM: 127.9
Min nTPM: 113.6
Sample A Male 113.6
Sample B Male 125.9
Sample C Female 124.0
Sample D Female 127.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

12.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.1
77620429 Antisense, RP_070205_01_H11, Mouse strain C57BL/6J (56 days, male) 16.1
79490112 Antisense, RP_070205_01_H11, Mouse strain C57BL/6J (56 days, male) 15.3
68196975 Antisense, RP_040928_01_A05, Mouse strain C57BL/6J (56 days, male) 8.0

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