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General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene namei
Official gene symbol, which is typically a short form of the gene name, according to HGNC.
Assigned HPA protein class(es) for the encoded protein(s).
Cancer-related genes Disease related genes Human disease related genes Transcription factors
Predicted locationi
All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.
Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.
Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).
The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Chromosome
15
Cytoband
q26.3
Chromosome location (bp)
99565417 - 99716488
Number of transcriptsi
Number of protein-coding transcripts from the gene as defined by Ensembl.
Useful information about the protein provided by UniProt.
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter....show less
Molecular function (UniProt)i
Keywords assigned by UniProt to proteins due to their particular molecular function.
Activator, Developmental protein, DNA-binding
Biological process (UniProt)i
Keywords assigned by UniProt to proteins because they are involved in a particular biological process.
The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]...show less
PROTEIN INFORMATIONi
The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.
The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.
The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes Human disease related genes Cardiovascular diseases Vascular diseases Protein evidence (Ezkurdia et al 2014)
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GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0005634[nucleus] GO:0006351[DNA-templated transcription] GO:0006355[regulation of DNA-templated transcription] GO:0007399[nervous system development] GO:0045893[positive regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046983[protein dimerization activity] GO:0048513[animal organ development]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors alpha-Helices exposed by beta-structures Cancer-related genes Mutational cancer driver genes Disease related genes Human disease related genes Cardiovascular diseases Vascular diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002[mitochondrial genome maintenance] GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000165[MAPK cascade] GO:0000785[chromatin] GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001228[DNA-binding transcription activator activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0003682[chromatin binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005667[transcription regulator complex] GO:0005829[cytosol] GO:0006351[DNA-templated transcription] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006915[apoptotic process] GO:0007399[nervous system development] GO:0007507[heart development] GO:0007517[muscle organ development] GO:0010613[positive regulation of cardiac muscle hypertrophy] GO:0030154[cell differentiation] GO:0035035[histone acetyltransferase binding] GO:0042826[histone deacetylase binding] GO:0043565[sequence-specific DNA binding] GO:0045893[positive regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046332[SMAD binding] GO:0046982[protein heterodimerization activity] GO:0046983[protein dimerization activity] GO:0048311[mitochondrion distribution] GO:0048513[animal organ development] GO:0048813[dendrite morphogenesis] GO:0055005[ventricular cardiac myofibril assembly] GO:0061337[cardiac conduction] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070375[ERK5 cascade] GO:0071277[cellular response to calcium ion] GO:0140297[DNA-binding transcription factor binding]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors alpha-Helices exposed by beta-structures Cancer-related genes Mutational cancer driver genes Disease related genes Human disease related genes Cardiovascular diseases Vascular diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002[mitochondrial genome maintenance] GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000165[MAPK cascade] GO:0000785[chromatin] GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001228[DNA-binding transcription activator activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0003682[chromatin binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005667[transcription regulator complex] GO:0005829[cytosol] GO:0006351[DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006915[apoptotic process] GO:0007399[nervous system development] GO:0007507[heart development] GO:0007517[muscle organ development] GO:0010613[positive regulation of cardiac muscle hypertrophy] GO:0030154[cell differentiation] GO:0035035[histone acetyltransferase binding] GO:0042826[histone deacetylase binding] GO:0043229[intracellular organelle] GO:0043565[sequence-specific DNA binding] GO:0045893[positive regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046332[SMAD binding] GO:0046982[protein heterodimerization activity] GO:0046983[protein dimerization activity] GO:0048311[mitochondrion distribution] GO:0048513[animal organ development] GO:0048813[dendrite morphogenesis] GO:0055005[ventricular cardiac myofibril assembly] GO:0061337[cardiac conduction] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070375[ERK5 cascade] GO:0071277[cellular response to calcium ion] GO:0140297[DNA-binding transcription factor binding]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors alpha-Helices exposed by beta-structures Cancer-related genes Mutational cancer driver genes Disease related genes Human disease related genes Cardiovascular diseases Vascular diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002[mitochondrial genome maintenance] GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000165[MAPK cascade] GO:0000785[chromatin] GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001228[DNA-binding transcription activator activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0003682[chromatin binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005667[transcription regulator complex] GO:0005829[cytosol] GO:0006351[DNA-templated transcription] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006915[apoptotic process] GO:0007399[nervous system development] GO:0007507[heart development] GO:0007517[muscle organ development] GO:0010613[positive regulation of cardiac muscle hypertrophy] GO:0030154[cell differentiation] GO:0035035[histone acetyltransferase binding] GO:0042826[histone deacetylase binding] GO:0043565[sequence-specific DNA binding] GO:0045893[positive regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046332[SMAD binding] GO:0046982[protein heterodimerization activity] GO:0046983[protein dimerization activity] GO:0048311[mitochondrion distribution] GO:0048513[animal organ development] GO:0048813[dendrite morphogenesis] GO:0055005[ventricular cardiac myofibril assembly] GO:0061337[cardiac conduction] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070375[ERK5 cascade] GO:0071277[cellular response to calcium ion] GO:0140297[DNA-binding transcription factor binding]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors alpha-Helices exposed by beta-structures Cancer-related genes Mutational cancer driver genes Disease related genes Human disease related genes Cardiovascular diseases Vascular diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002[mitochondrial genome maintenance] GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000165[MAPK cascade] GO:0000785[chromatin] GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001228[DNA-binding transcription activator activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0003682[chromatin binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005667[transcription regulator complex] GO:0005829[cytosol] GO:0006351[DNA-templated transcription] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006915[apoptotic process] GO:0007399[nervous system development] GO:0007507[heart development] GO:0007517[muscle organ development] GO:0010613[positive regulation of cardiac muscle hypertrophy] GO:0010628[positive regulation of gene expression] GO:0019901[protein kinase binding] GO:0030154[cell differentiation] GO:0035035[histone acetyltransferase binding] GO:0042826[histone deacetylase binding] GO:0043565[sequence-specific DNA binding] GO:0045893[positive regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046326[positive regulation of glucose import] GO:0046332[SMAD binding] GO:0046982[protein heterodimerization activity] GO:0046983[protein dimerization activity] GO:0048311[mitochondrion distribution] GO:0048513[animal organ development] GO:0048813[dendrite morphogenesis] GO:0055005[ventricular cardiac myofibril assembly] GO:0061337[cardiac conduction] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070375[ERK5 cascade] GO:0071277[cellular response to calcium ion] GO:0140297[DNA-binding transcription factor binding]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes Human disease related genes Cardiovascular diseases Vascular diseases Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0005634[nucleus] GO:0006351[DNA-templated transcription] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0045893[positive regulation of DNA-templated transcription] GO:0046983[protein dimerization activity] GO:0048513[animal organ development]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors alpha-Helices exposed by beta-structures Cancer-related genes Mutational cancer driver genes Disease related genes Human disease related genes Cardiovascular diseases Vascular diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002[mitochondrial genome maintenance] GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000165[MAPK cascade] GO:0000785[chromatin] GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001228[DNA-binding transcription activator activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0003682[chromatin binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005667[transcription regulator complex] GO:0005829[cytosol] GO:0006351[DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006915[apoptotic process] GO:0007399[nervous system development] GO:0007507[heart development] GO:0007517[muscle organ development] GO:0010613[positive regulation of cardiac muscle hypertrophy] GO:0030154[cell differentiation] GO:0035035[histone acetyltransferase binding] GO:0042826[histone deacetylase binding] GO:0043565[sequence-specific DNA binding] GO:0045893[positive regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046332[SMAD binding] GO:0046982[protein heterodimerization activity] GO:0046983[protein dimerization activity] GO:0048311[mitochondrion distribution] GO:0048513[animal organ development] GO:0048813[dendrite morphogenesis] GO:0055005[ventricular cardiac myofibril assembly] GO:0061337[cardiac conduction] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070375[ERK5 cascade] GO:0071277[cellular response to calcium ion] GO:0140297[DNA-binding transcription factor binding]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes Human disease related genes Cardiovascular diseases Vascular diseases Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0005634[nucleus] GO:0006351[DNA-templated transcription] GO:0006355[regulation of DNA-templated transcription] GO:0045893[positive regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046983[protein dimerization activity] GO:0048513[animal organ development]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes Human disease related genes Cardiovascular diseases Vascular diseases Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0005634[nucleus] GO:0006351[DNA-templated transcription] GO:0006355[regulation of DNA-templated transcription] GO:0045893[positive regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046983[protein dimerization activity] GO:0048513[animal organ development]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes Human disease related genes Cardiovascular diseases Vascular diseases Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0005634[nucleus] GO:0006351[DNA-templated transcription] GO:0006355[regulation of DNA-templated transcription] GO:0007399[nervous system development] GO:0045893[positive regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046983[protein dimerization activity] GO:0048513[animal organ development]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors alpha-Helices exposed by beta-structures Cancer-related genes Mutational cancer driver genes Disease related genes Human disease related genes Cardiovascular diseases Vascular diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002[mitochondrial genome maintenance] GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000165[MAPK cascade] GO:0000785[chromatin] GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001228[DNA-binding transcription activator activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0003682[chromatin binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005667[transcription regulator complex] GO:0005829[cytosol] GO:0006351[DNA-templated transcription] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006915[apoptotic process] GO:0007399[nervous system development] GO:0007507[heart development] GO:0007517[muscle organ development] GO:0010613[positive regulation of cardiac muscle hypertrophy] GO:0030154[cell differentiation] GO:0035035[histone acetyltransferase binding] GO:0042826[histone deacetylase binding] GO:0043565[sequence-specific DNA binding] GO:0045893[positive regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046332[SMAD binding] GO:0046982[protein heterodimerization activity] GO:0046983[protein dimerization activity] GO:0048311[mitochondrion distribution] GO:0048513[animal organ development] GO:0048813[dendrite morphogenesis] GO:0055005[ventricular cardiac myofibril assembly] GO:0061337[cardiac conduction] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070375[ERK5 cascade] GO:0071277[cellular response to calcium ion] GO:0140297[DNA-binding transcription factor binding]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes Human disease related genes Cardiovascular diseases Vascular diseases Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0005634[nucleus] GO:0006351[DNA-templated transcription] GO:0006355[regulation of DNA-templated transcription] GO:0007399[nervous system development] GO:0045893[positive regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046983[protein dimerization activity] GO:0048513[animal organ development]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors alpha-Helices exposed by beta-structures Cancer-related genes Mutational cancer driver genes Disease related genes Human disease related genes Cardiovascular diseases Vascular diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002[mitochondrial genome maintenance] GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000165[MAPK cascade] GO:0000785[chromatin] GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001228[DNA-binding transcription activator activity, RNA polymerase II-specific] GO:0003677[DNA binding] GO:0003682[chromatin binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005667[transcription regulator complex] GO:0005829[cytosol] GO:0006351[DNA-templated transcription] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006915[apoptotic process] GO:0007399[nervous system development] GO:0007507[heart development] GO:0007517[muscle organ development] GO:0010613[positive regulation of cardiac muscle hypertrophy] GO:0030154[cell differentiation] GO:0035035[histone acetyltransferase binding] GO:0042826[histone deacetylase binding] GO:0043565[sequence-specific DNA binding] GO:0045893[positive regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046332[SMAD binding] GO:0046982[protein heterodimerization activity] GO:0046983[protein dimerization activity] GO:0048311[mitochondrion distribution] GO:0048513[animal organ development] GO:0048813[dendrite morphogenesis] GO:0055005[ventricular cardiac myofibril assembly] GO:0061337[cardiac conduction] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070375[ERK5 cascade] GO:0071277[cellular response to calcium ion] GO:0140297[DNA-binding transcription factor binding]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes Human disease related genes Cardiovascular diseases Vascular diseases Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977[RNA polymerase II transcription regulatory region sequence-specific DNA binding] GO:0003677[DNA binding] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0046983[protein dimerization activity]
The Human Protein Atlas project is funded
