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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:119.1 nTPM
HPA Brain:276.2 nTPM
GTEx:119.1 nTPM
FANTOM5:722.2 Scaled Tags Per Million
Pig:202.5 nTPM
Mouse:107.7 nTPM
Allen mouse:2.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

276.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 214.7
2411 Female, age 72, unknown 287.1
1870 Female, age 42, unknown 272.1
1830 Male, age 51, unknown 268.8
1833 Male, age 53, unknown 257.7
2019 Male, age 18, unknown 255.8
2828 Female, age 72, unknown 200.6
2666 Male, age 74, left hemisphere 163.1
2219 Male, age 76, both hemispheres 156.5
1827 Male, age 72, unknown 153.0
2586 Male, age 75, left hemisphere 131.8
Dorsal raphe nucleus
nTPM: 178.3
2750 Male, age 76, both hemispheres 297.7
2016 Female, age 72, unknown 193.5
1828 Male, age 53, unknown 162.2
2298 Female, age 72, unknown 123.2
2047 Male, age 72, unknown 115.2
Inferior colliculus
nTPM: 145.9
1890 Male, age 53, unknown 159.8
1848 Female, age 42, unknown 148.0
2097 Female, age 72, unknown 140.5
2849 Male, age 72, unknown 135.3
Median raphe nucleus
nTPM: 128.6
2220 Male, age 76, midline 128.6
Periaquaductal grey, anterior
nTPM: 139.5
2502 Female, age 75, unknown 166.7
1947 Male, age 18, unknown 148.1
1795 Male, age 51, unknown 103.5
Periaquaductal grey, dorsal
nTPM: 125.6
2464 Female, age 72, unknown 180.1
2850 Male, age 76, both hemispheres 122.3
1831 Male, age 72, unknown 116.3
1840 Male, age 53, unknown 83.6
Periaquaductal grey, lateral
nTPM: 138.4
2272 Male, age 74, both hemispheres 154.8
2053 Male, age 18, unknown 141.0
2140 Male, age 76, both hemispheres 119.3
Pretectal area
nTPM: 144.1
2316 Male, age 76, right hemisphere 204.7
1815 Male, age 53, unknown 198.1
2273 Male, age 74, both hemispheres 156.0
1817 Female, age 42, unknown 153.9
2007 Male, age 72, unknown 151.6
2825 Male, age 18, unknown 146.5
2407 Male, age 75, both hemispheres 133.7
2667 Female, age 75, unknown 131.5
2224 Female, age 72, unknown 126.6
1944 Female, age 72, unknown 92.3
1816 Male, age 51, unknown 90.4
Red nucleus
nTPM: 276.2
1865 Male, age 51, unknown 346.9
1821 Female, age 72, unknown 344.0
1904 Male, age 53, unknown 332.1
2769 Male, age 72, unknown 298.8
2227 Male, age 72, unknown 296.2
2503 Female, age 72, unknown 289.8
2785 Male, age 18, unknown 285.9
2823 Male, age 76, right hemisphere 283.1
1954 Female, age 42, unknown 278.3
2588 Male, age 74, left hemisphere 217.9
2725 Female, age 75, unknown 194.6
2584 Male, age 75, left hemisphere 146.8
Substantia nigra
nTPM: 167.1
2409 Female, age 72, unknown 235.0
1851 Male, age 51, unknown 198.2
2590 Female, age 75, unknown 184.8
1889 Female, age 72, unknown 178.2
2241 Male, age 72, unknown 170.0
2699 Male, age 18, unknown 160.5
2583 Male, age 75, right hemisphere 154.0
1941 Male, age 53, unknown 144.3
1916 Female, age 42, unknown 132.4
2665 Male, age 74, both hemispheres 114.0
Superior colliculus
nTPM: 181.3
1913 Female, age 42, unknown 283.8
1995 Male, age 72, unknown 272.6
1895 Male, age 76, right hemisphere 216.5
2587 Male, age 74, left hemisphere 210.0
1839 Male, age 51, unknown 189.4
2668 Female, age 75, unknown 182.3
1796 Male, age 53, unknown 134.1
2261 Male, age 18, unknown 113.8
2087 Female, age 72, unknown 112.7
2664 Male, age 75, both hemispheres 98.0
Ventral tegmental area
nTPM: 186.9
2410 Female, age 72, unknown 256.5
2223 Female, age 72, unknown 230.1
1942 Male, age 51, unknown 165.1
2021 Male, age 53, unknown 164.6
1915 Female, age 42, unknown 163.4
2218 Male, age 76, both hemispheres 141.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

119.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 119.1
Samples: 139

Max nTPM: 338.8
Min nTPM: 50.0
Std nTPM: 49.3
Median nTPM: 110.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 338.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 283.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 276.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 251.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 243.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 230.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 219.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 215.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 208.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 207.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 202.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 195.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 190.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 177.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 177.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 177.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 173.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 169.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 169.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 168.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 165.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 162.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 161.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 159.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 156.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 155.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 154.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 146.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 139.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 139.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 138.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 138.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 137.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 136.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 135.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 135.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 134.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 132.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 132.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 132.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 129.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 128.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 127.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 125.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 125.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 125.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 125.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 124.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 123.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 122.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 121.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 121.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 120.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 120.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 120.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 118.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 118.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 117.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 116.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 116.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 115.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 114.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 114.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 113.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 113.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 112.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 111.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 111.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 110.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 110.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 109.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 109.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 108.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 108.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 108.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 107.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 106.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 106.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 106.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 106.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 105.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 103.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 102.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 101.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 101.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 99.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 98.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 97.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 97.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 97.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 95.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 94.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 94.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 93.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 93.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 91.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 91.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 91.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 90.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 87.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 86.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 85.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 82.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 82.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 82.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 81.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 81.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 81.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 81.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 81.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 80.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 79.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 78.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 78.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 77.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 76.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 75.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 74.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 73.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 73.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 72.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 72.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 71.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 70.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 70.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 67.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 67.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 66.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 66.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 66.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 63.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 62.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 59.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 59.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 59.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 56.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 54.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 51.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 50.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

722.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 722.2
FF:10158-103A5 76 years, female 722.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

202.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 187.3
Samples: 4

Max nTPM: 281.7
Min nTPM: 135.2
Sample A Female 191.3
Sample B Female 135.2
Sample C Male 140.8
Sample D Male 281.7
Midbrain
nTPM: 202.5
Samples: 4

Max nTPM: 370.7
Min nTPM: 106.0
Sample A Female 370.7
Sample B Female 225.9
Sample C Male 107.2
Sample D Male 106.0
Periaqueductal gray
nTPM: 149.0
Samples: 3

Max nTPM: 189.3
Min nTPM: 111.7
Sample B Female 189.3
Sample C Male 111.7
Sample D Male 145.9
Superior colliculi
nTPM: 148.1
Samples: 4

Max nTPM: 167.1
Min nTPM: 112.1
Sample A Female 161.9
Sample B Female 112.1
Sample C Male 151.2
Sample D Male 167.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

107.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 107.7
Samples: 4

Max nTPM: 116.6
Min nTPM: 97.8
Sample A Male 97.8
Sample B Male 102.9
Sample C Female 116.6
Sample D Female 113.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.9
77925099 Antisense, RP_070320_02_C03, Mouse strain C57BL/6J (56 days, male) 6.5
68499189 Antisense, RP_050118_01_B02, Mouse strain C57BL/6J (56 days, male) 2.0
74749271 Antisense, RP_051219_01_B09, Mouse strain C57BL/6J (56 days, male) 0.1

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