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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:48.3 nTPM
HPA Brain:60.0 nTPM
GTEx:48.3 nTPM
FANTOM5:136.2 Scaled Tags Per Million
Pig:46.6 nTPM
Mouse:29.1 nTPM
Allen mouse:0.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

60.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 47.7
1870 Female, age 42, unknown 57.6
2411 Female, age 72, unknown 55.0
1827 Male, age 72, unknown 54.4
2828 Female, age 72, unknown 51.0
1833 Male, age 53, unknown 49.2
1830 Male, age 51, unknown 46.2
2019 Male, age 18, unknown 45.2
2219 Male, age 76, both hemispheres 44.7
2666 Male, age 74, left hemisphere 37.5
2586 Male, age 75, left hemisphere 36.8
Dorsal raphe nucleus
nTPM: 51.5
2298 Female, age 72, unknown 60.5
2750 Male, age 76, both hemispheres 57.4
2047 Male, age 72, unknown 52.7
1828 Male, age 53, unknown 46.5
2016 Female, age 72, unknown 40.3
Inferior colliculus
nTPM: 45.6
2097 Female, age 72, unknown 54.6
1848 Female, age 42, unknown 48.0
1890 Male, age 53, unknown 41.2
2849 Male, age 72, unknown 38.7
Median raphe nucleus
nTPM: 60.0
2220 Male, age 76, midline 60.0
Periaquaductal grey, anterior
nTPM: 50.0
1947 Male, age 18, unknown 56.0
2502 Female, age 75, unknown 51.7
1795 Male, age 51, unknown 42.2
Periaquaductal grey, dorsal
nTPM: 44.0
2850 Male, age 76, both hemispheres 50.1
2464 Female, age 72, unknown 44.3
1840 Male, age 53, unknown 41.3
1831 Male, age 72, unknown 40.0
Periaquaductal grey, lateral
nTPM: 44.3
2053 Male, age 18, unknown 47.3
2140 Male, age 76, both hemispheres 47.1
2272 Male, age 74, both hemispheres 38.7
Pretectal area
nTPM: 48.9
2667 Female, age 75, unknown 55.6
1817 Female, age 42, unknown 55.1
1815 Male, age 53, unknown 53.7
2007 Male, age 72, unknown 52.6
2224 Female, age 72, unknown 52.4
1816 Male, age 51, unknown 51.8
1944 Female, age 72, unknown 47.1
2825 Male, age 18, unknown 45.6
2273 Male, age 74, both hemispheres 44.3
2316 Male, age 76, right hemisphere 43.1
2407 Male, age 75, both hemispheres 36.0
Red nucleus
nTPM: 49.3
1821 Female, age 72, unknown 64.2
1865 Male, age 51, unknown 55.6
1954 Female, age 42, unknown 54.9
1904 Male, age 53, unknown 52.8
2725 Female, age 75, unknown 51.0
2503 Female, age 72, unknown 50.9
2769 Male, age 72, unknown 49.1
2227 Male, age 72, unknown 48.7
2823 Male, age 76, right hemisphere 48.0
2785 Male, age 18, unknown 43.2
2588 Male, age 74, left hemisphere 42.4
2584 Male, age 75, left hemisphere 30.5
Substantia nigra
nTPM: 50.7
1916 Female, age 42, unknown 67.4
1851 Male, age 51, unknown 58.9
1889 Female, age 72, unknown 56.4
1941 Male, age 53, unknown 54.8
2241 Male, age 72, unknown 54.6
2409 Female, age 72, unknown 53.9
2699 Male, age 18, unknown 50.1
2590 Female, age 75, unknown 39.4
2583 Male, age 75, right hemisphere 37.4
2665 Male, age 74, both hemispheres 34.5
Superior colliculus
nTPM: 44.8
2587 Male, age 74, left hemisphere 49.8
1796 Male, age 53, unknown 48.5
1895 Male, age 76, right hemisphere 48.1
1913 Female, age 42, unknown 47.2
2087 Female, age 72, unknown 46.6
2261 Male, age 18, unknown 45.7
1839 Male, age 51, unknown 45.3
2668 Female, age 75, unknown 44.7
1995 Male, age 72, unknown 39.6
2664 Male, age 75, both hemispheres 32.4
Ventral tegmental area
nTPM: 56.4
2410 Female, age 72, unknown 66.4
2218 Male, age 76, both hemispheres 64.0
2223 Female, age 72, unknown 58.7
1915 Female, age 42, unknown 56.4
2021 Male, age 53, unknown 47.2
1942 Male, age 51, unknown 45.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

48.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 48.3
Samples: 139

Max nTPM: 86.7
Min nTPM: 25.3
Std nTPM: 11.2
Median nTPM: 46.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 86.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 81.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 79.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 79.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 76.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 71.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 70.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 70.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 69.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 68.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 64.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 63.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 63.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 63.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 62.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 62.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 62.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 60.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 59.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 59.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 59.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 59.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 58.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 58.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 58.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 58.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 57.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 57.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 56.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 55.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 55.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 55.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 55.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 55.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 54.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 53.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 52.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 52.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 52.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 52.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 52.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 52.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 51.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 51.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 50.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 50.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 50.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 49.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 49.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 49.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 49.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 49.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 49.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 49.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 49.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 49.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 49.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 49.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 48.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 48.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 48.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 48.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 48.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 48.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 47.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 47.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 47.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 47.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 47.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 46.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 46.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 46.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 46.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 46.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 45.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 45.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 45.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 45.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 45.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 45.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 45.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 45.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 45.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 45.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 44.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 44.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 43.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 43.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 43.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 43.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 43.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 42.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 42.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 42.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 42.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 42.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 42.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 41.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 41.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 41.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 41.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 41.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 41.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 40.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 40.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 40.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 39.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 39.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 39.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 39.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 39.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 39.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 39.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 38.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 38.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 38.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 38.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 38.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 37.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 37.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 37.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 36.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 36.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 35.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 35.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 35.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 34.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 34.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 34.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 34.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 34.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 34.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 33.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 32.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 32.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 28.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 28.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 25.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 25.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

136.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 136.2
FF:10158-103A5 76 years, female 136.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

46.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 38.5
Samples: 4

Max nTPM: 42.6
Min nTPM: 31.6
Sample A Female 40.5
Sample B Female 31.6
Sample C Male 42.6
Sample D Male 39.4
Midbrain
nTPM: 46.6
Samples: 4

Max nTPM: 58.8
Min nTPM: 37.2
Sample A Female 58.8
Sample B Female 39.2
Sample C Male 51.1
Sample D Male 37.2
Periaqueductal gray
nTPM: 40.7
Samples: 3

Max nTPM: 43.4
Min nTPM: 37.0
Sample B Female 41.8
Sample C Male 43.4
Sample D Male 37.0
Superior colliculi
nTPM: 39.1
Samples: 4

Max nTPM: 43.8
Min nTPM: 36.0
Sample A Female 38.2
Sample B Female 36.0
Sample C Male 43.8
Sample D Male 38.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

29.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 29.1
Samples: 4

Max nTPM: 31.0
Min nTPM: 28.2
Sample A Male 28.5
Sample B Male 28.5
Sample C Female 31.0
Sample D Female 28.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.3
69549651 Antisense, RP_050315_01_C02, Mouse strain C57BL/6J (56 days, male) 0.3

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