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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
102.4
nTPM
HPA:
102.4
nTPM
GTEx:
85.5
nTPM
FANTOM5:
262.6
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA031707
Antibody HPA031708
Antibody HPA032045
Antibody CAB017840
Cholangiocytes
Not detected
Not detected
Not detected
Not detected
Hepatocytes
Not detected
Low
Not detected
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
102.4
Female, age 60
Liver sample 21 nTPM: 92.9
Male, age 54
Liver sample 23 nTPM: 95.2
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 77.7
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 131.3
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 122.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 101.6
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 93.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 103.6
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 100.9
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 104.7
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
85.5
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 85.5
Samples: 226
Max nTPM: 198.9
Min nTPM: 32.7
Std nTPM: 34.2
Median nTPM: 77.1
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
198.9
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
182.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
181.4
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
180.7
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
176.6
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
168.9
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
165.7
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
164.4
GTEX-14XAO-0226-SM-68728
60-69 years, female
163.5
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
158.4
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
158.1
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
156.8
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
153.3
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
152.4
GTEX-O5YV-0726-SM-EV798
60-69 years, female
150.6
GTEX-S33H-1626-SM-4AD68
30-39 years, male
149.1
GTEX-S32W-1926-SM-4AD63
50-59 years, female
147.5
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
147.3
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
143.7
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
140.8
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
140.3
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
139.2
GTEX-12696-0826-SM-5EGGE
60-69 years, male
135.5
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
135.0
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
133.5
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
133.3
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
132.5
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
130.5
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
129.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
126.7
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
124.5
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
124.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
124.0
GTEX-1B932-1426-SM-793AN
40-49 years, female
122.7
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
121.6
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
121.6
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
121.2
GTEX-P78B-1326-SM-3P611
40-49 years, female
121.0
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
119.1
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
118.4
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
116.4
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
115.1
GTEX-REY6-1226-SM-48FDR
60-69 years, male
113.5
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
113.1
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
110.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
110.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
109.3
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
109.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
108.1
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
107.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
107.1
GTEX-Q734-0326-SM-48U15
40-49 years, female
107.0
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
106.2
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
106.0
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
104.6
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
104.3
GTEX-18A66-2026-SM-7189C
60-69 years, male
104.0
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
103.3
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
101.7
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
101.7
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
101.6
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
101.1
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
100.9
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
100.8
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
100.7
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
99.8
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
99.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
99.2
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
97.5
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
97.2
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
95.9
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
95.5
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
95.4
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
93.5
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
93.3
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
93.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
93.1
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
93.1
GTEX-13113-1326-SM-5GCOI
60-69 years, female
92.4
GTEX-1399T-0826-SM-5IFES
60-69 years, male
92.0
GTEX-R53T-0326-SM-48FEC
50-59 years, female
91.1
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
90.9
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
90.7
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
89.0
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
87.4
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
87.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
86.8
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
86.5
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
85.5
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
85.2
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
85.0
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
85.0
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
84.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
84.2
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
84.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
84.0
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
83.7
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
83.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
83.6
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
82.7
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
82.5
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
82.4
GTEX-17HHE-0126-SM-79398
50-59 years, male
82.2
GTEX-14JG1-1626-SM-664NH
40-49 years, male
81.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
80.9
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
80.4
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
80.2
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
80.2
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
79.0
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
78.7
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
77.7
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
77.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
77.5
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
76.6
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
76.5
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
76.4
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
76.3
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
76.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
76.1
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
75.6
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
75.6
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
75.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
74.9
GTEX-14PHX-0526-SM-664NW
50-59 years, male
74.4
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
72.7
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
72.6
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
72.3
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
72.0
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
72.0
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
71.8
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
71.7
GTEX-RU72-1426-SM-46MUF
50-59 years, female
71.5
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
71.2
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
71.0
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
69.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
69.4
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
69.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
68.7
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
68.4
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
68.0
GTEX-18A7A-1526-SM-72D69
50-59 years, female
67.5
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
67.4
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
67.2
GTEX-14E7W-1526-SM-6871X
70-79 years, male
67.2
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
67.1
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
67.1
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
66.3
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
66.3
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
66.1
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
66.0
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
65.0
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
64.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
63.9
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
63.9
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
63.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
63.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
63.5
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
63.0
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
62.8
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
62.5
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
61.8
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
61.8
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
61.4
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
60.6
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
60.5
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
59.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
59.0
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
58.9
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
58.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
58.7
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
58.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
58.0
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
57.9
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
57.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
57.6
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
57.5
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
56.9
GTEX-11ZUS-2526-SM-59872
30-39 years, male
56.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
56.5
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
56.3
GTEX-QESD-2026-SM-447BI
20-29 years, male
56.3
GTEX-13112-1426-SM-5EGH8
50-59 years, male
56.1
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
56.0
GTEX-RN64-1826-SM-48FDV
50-59 years, male
55.5
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
55.3
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
54.9
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
54.8
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
54.5
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
54.0
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
53.4
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
53.0
GTEX-18465-1626-SM-7LG6N
50-59 years, male
52.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
51.4
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
51.2
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
51.0
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
50.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
49.9
GTEX-14PJO-1726-SM-68719
60-69 years, male
49.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
49.0
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
48.7
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
48.6
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
48.5
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
48.2
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
48.1
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
48.1
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
47.5
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
47.3
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
47.2
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
47.0
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
46.7
GTEX-17F96-1226-SM-79OK2
70-79 years, male
46.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
46.6
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
46.2
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
45.6
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
45.0
GTEX-144GL-1426-SM-79OMA
50-59 years, male
44.8
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
44.3
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
43.8
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
43.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
43.0
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
42.9
GTEX-1B933-1226-SM-731DW
50-59 years, female
41.2
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
40.8
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
40.4
GTEX-11GSP-0626-SM-5986T
60-69 years, female
36.6
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
32.7
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
