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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:23.6 nTPM
HPA Brain:121.7 nTPM
GTEx:23.6 nTPM
FANTOM5:5.6 Scaled Tags Per Million
Pig:30.9 nTPM
Mouse:49.4 nTPM
Allen mouse:0.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

121.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 88.8
2219 Male, age 76, both hemispheres 158.5
2586 Male, age 75, left hemisphere 108.0
2019 Male, age 18, unknown 103.5
2666 Male, age 74, left hemisphere 99.5
2828 Female, age 72, unknown 88.5
1827 Male, age 72, unknown 85.6
1870 Female, age 42, unknown 65.2
2411 Female, age 72, unknown 64.7
1830 Male, age 51, unknown 61.1
1833 Male, age 53, unknown 53.2
Dorsal raphe nucleus
nTPM: 73.7
2298 Female, age 72, unknown 93.8
2047 Male, age 72, unknown 89.8
2750 Male, age 76, both hemispheres 66.2
1828 Male, age 53, unknown 63.8
2016 Female, age 72, unknown 55.1
Inferior colliculus
nTPM: 84.7
2097 Female, age 72, unknown 98.3
1890 Male, age 53, unknown 96.0
1848 Female, age 42, unknown 75.8
2849 Male, age 72, unknown 68.7
Median raphe nucleus
nTPM: 98.5
2220 Male, age 76, midline 98.5
Periaquaductal grey, anterior
nTPM: 121.7
2502 Female, age 75, unknown 155.3
1795 Male, age 51, unknown 117.3
1947 Male, age 18, unknown 92.5
Periaquaductal grey, dorsal
nTPM: 85.4
1840 Male, age 53, unknown 97.1
1831 Male, age 72, unknown 90.4
2464 Female, age 72, unknown 87.4
2850 Male, age 76, both hemispheres 66.8
Periaquaductal grey, lateral
nTPM: 71.3
2140 Male, age 76, both hemispheres 79.1
2053 Male, age 18, unknown 68.7
2272 Male, age 74, both hemispheres 65.9
Pretectal area
nTPM: 103.0
1816 Male, age 51, unknown 166.4
1944 Female, age 72, unknown 147.0
2007 Male, age 72, unknown 142.0
1817 Female, age 42, unknown 120.6
2667 Female, age 75, unknown 109.8
1815 Male, age 53, unknown 102.0
2224 Female, age 72, unknown 88.3
2316 Male, age 76, right hemisphere 74.7
2825 Male, age 18, unknown 70.0
2407 Male, age 75, both hemispheres 65.4
2273 Male, age 74, both hemispheres 46.7
Red nucleus
nTPM: 58.0
2785 Male, age 18, unknown 100.0
2584 Male, age 75, left hemisphere 85.0
2588 Male, age 74, left hemisphere 58.8
2227 Male, age 72, unknown 57.6
2503 Female, age 72, unknown 56.1
1954 Female, age 42, unknown 54.1
2725 Female, age 75, unknown 52.9
1904 Male, age 53, unknown 51.7
2769 Male, age 72, unknown 48.2
2823 Male, age 76, right hemisphere 48.0
1865 Male, age 51, unknown 44.9
1821 Female, age 72, unknown 38.1
Substantia nigra
nTPM: 77.6
2665 Male, age 74, both hemispheres 118.3
1889 Female, age 72, unknown 113.3
1941 Male, age 53, unknown 93.2
1916 Female, age 42, unknown 89.2
1851 Male, age 51, unknown 78.3
2241 Male, age 72, unknown 72.2
2590 Female, age 75, unknown 65.9
2699 Male, age 18, unknown 52.9
2409 Female, age 72, unknown 48.9
2583 Male, age 75, right hemisphere 44.0
Superior colliculus
nTPM: 91.5
2087 Female, age 72, unknown 143.2
2664 Male, age 75, both hemispheres 106.0
1796 Male, age 53, unknown 105.7
2261 Male, age 18, unknown 103.4
1895 Male, age 76, right hemisphere 101.7
2587 Male, age 74, left hemisphere 80.8
1839 Male, age 51, unknown 70.6
1913 Female, age 42, unknown 70.5
2668 Female, age 75, unknown 70.5
1995 Male, age 72, unknown 62.6
Ventral tegmental area
nTPM: 85.2
2218 Male, age 76, both hemispheres 104.0
1942 Male, age 51, unknown 100.5
1915 Female, age 42, unknown 81.2
2021 Male, age 53, unknown 78.1
2223 Female, age 72, unknown 73.9
2410 Female, age 72, unknown 73.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

23.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 23.6
Samples: 139

Max nTPM: 63.0
Min nTPM: 3.6
Std nTPM: 12.1
Median nTPM: 23.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 63.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 51.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 49.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 48.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 48.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 47.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 47.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 44.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 43.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 42.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 41.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 41.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 40.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 39.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 38.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 38.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 37.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 36.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 36.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 36.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 36.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 36.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 36.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 35.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 35.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 34.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 34.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 34.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 34.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 34.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 34.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 33.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 33.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 33.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 33.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 32.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 32.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 31.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 31.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 31.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 30.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 30.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 29.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 29.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 29.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 28.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 28.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 28.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 28.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 28.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 27.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 27.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 27.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 27.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 27.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 26.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 26.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 26.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 26.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 26.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 25.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 25.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 24.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 24.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 24.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 23.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 23.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 23.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 23.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 23.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 22.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 22.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 22.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 22.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 22.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 21.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 21.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 20.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 20.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 20.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 19.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 19.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 19.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 19.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 19.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 18.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 18.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 18.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 17.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 17.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 17.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 16.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 16.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 16.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 15.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 15.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 15.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 14.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 14.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 14.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 13.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 13.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 13.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 13.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 12.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 12.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 12.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 12.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 12.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 12.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 11.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 11.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 11.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 11.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 10.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 10.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 10.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 10.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 9.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 9.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 9.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 9.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 8.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 8.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 8.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 8.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 7.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 7.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 7.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 7.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 7.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 6.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 6.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 6.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 5.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 4.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 4.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 3.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 3.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

5.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 5.6
FF:10158-103A5 76 years, female 5.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

30.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 18.9
Samples: 4

Max nTPM: 30.9
Min nTPM: 5.4
Sample A Female 25.2
Sample B Female 13.9
Sample C Male 30.9
Sample D Male 5.4
Midbrain
nTPM: 30.9
Samples: 4

Max nTPM: 67.3
Min nTPM: 3.8
Sample A Female 3.8
Sample B Female 15.2
Sample C Male 67.3
Sample D Male 37.2
Periaqueductal gray
nTPM: 15.3
Samples: 3

Max nTPM: 20.1
Min nTPM: 12.5
Sample B Female 13.4
Sample C Male 20.1
Sample D Male 12.5
Superior colliculi
nTPM: 26.1
Samples: 4

Max nTPM: 39.2
Min nTPM: 12.0
Sample A Female 22.9
Sample B Female 12.0
Sample C Male 39.2
Sample D Male 30.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

49.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 49.4
Samples: 4

Max nTPM: 54.8
Min nTPM: 43.7
Sample A Male 43.7
Sample B Male 48.5
Sample C Female 54.8
Sample D Female 50.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.9
73496947 Antisense, RP_051019_04_A10, Mouse strain C57BL/6J (56 days, male) 0.9

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