GENERAL INFORMATIONi
Gene namei DLG1
Synonyms dJ1061C18.1.1, DLGH1, hdlg, SAP-97, SAP97
Gene descriptioni Discs large MAGUK scaffold protein 1
Protein classi Transporters
Predicted locationi Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi
Chromosome 3
Cytoband q29
Chromosome location (bp) 197042560 - 197299330
Number of transcriptsi 46
Ensembl ENSG00000075711 (version 109)
Entrez gene 1739
HGNC HGNC:2900
UniProt Q12959 (UniProt - Evidence at protein level)
neXtProt NX_Q12959
GeneCards DLG1
Antibodypedia DLG1 antibodies


PROTEIN FUNCTION
Protein function (UniProt)i Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel. During long-term depression in hippocampal neurons, it recruits ADAM10 to the plasma membrane 1. show less
Biological process (UniProt)i Host-virus interaction
Gene summary (Entrez)i This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. A multitude of transcript variants deriving from alternative splicing and the use of multiple alternate promoter have been observed, including some splice variants that may be specific to brain and other tissues. An upstream uORF may regulate translation at some splice variants of this gene. [provided by RefSeq, Sep 2018] show less
PROTEIN INFORMATIONi
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)		 Transmembrane regions
(predicted)
DLG1-201
ENSP00000345731
ENST00000346964
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 926 aa
103.3 kDa 		No 0
DLG1-202
ENSP00000350303
ENST00000357674
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 893 aa
99.9 kDa 		No 0
DLG1-203
ENSP00000376185
ENST00000392380
A8MUT6
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 208 aa
23.3 kDa 		No 0
DLG1-205
ENSP00000376187
ENST00000392382
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 871 aa
97.1 kDa 		No 0
DLG1-206
ENSP00000390403
ENST00000412364
F2Z2L0
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 106 aa
12.2 kDa 		No 0
DLG1-208
ENSP00000407531
ENST00000419354
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 904 aa
100.5 kDa 		No 0
DLG1-210
ENSP00000413238
ENST00000422288
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 853 aa
95.2 kDa 		No 0
DLG1-211
ENSP00000400169
ENST00000434148
C9J110
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 35 aa
4.2 kDa 		No 0
DLG1-212
ENSP00000393771
ENST00000436682
C9JUA9
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 551 aa
63.1 kDa 		No 0
DLG1-213
ENSP00000396658
ENST00000443183
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 800 aa
88.5 kDa 		No 0
DLG1-214
ENSP00000398702
ENST00000447466
H7C166
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 286 aa
30.5 kDa 		No 0
DLG1-215
ENSP00000391732
ENST00000448528
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 904 aa
100.5 kDa 		No 0
DLG1-216
ENSP00000411278
ENST00000450955
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 893 aa
99.9 kDa 		No 0
DLG1-217
ENSP00000398939
ENST00000452595
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 788 aa
87.2 kDa 		No 0
DLG1-218
ENSP00000412579
ENST00000453607
C9IYP1
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 122 aa
13.3 kDa 		No 0
DLG1-219
ENSP00000396474
ENST00000456699
C9JCP6
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 179 aa
20.4 kDa 		No 0
DLG1-231
ENSP00000499599
ENST00000653795
A0A590UJX2
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0030054 [cell junction]
Show all
 833 aa
91.9 kDa 		No 0
DLG1-232
ENSP00000499730
ENST00000654733
A0A590UK81
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0030054 [cell junction]
Show all
 772 aa
85.4 kDa 		No 0
DLG1-233
ENSP00000499578
ENST00000654737
A0A590UJS9
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 839 aa
93.6 kDa 		No 0
DLG1-234
ENSP00000499657
ENST00000655488
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 871 aa
97.1 kDa 		No 0
DLG1-235
ENSP00000499723
ENST00000656087
A0A590UKA8
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 883 aa
98.3 kDa 		No 0
DLG1-236
ENSP00000499329
ENST00000656428
A0A590UJ81
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0030054 [cell junction]
Show all
 874 aa
96.6 kDa 		No 0
DLG1-237
ENSP00000499584
ENST00000656944
A0A0C4DFT3
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 892 aa
99.8 kDa 		No 0
DLG1-239
ENSP00000499507
ENST00000657381
A0A0C4DFT3
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 892 aa
99.8 kDa 		No 0
DLG1-240
ENSP00000499257
ENST00000658155
A0A590UJ29
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0030054 [cell junction]
Show all
 744 aa
82.3 kDa 		No 0
DLG1-241
ENSP00000499531
ENST00000658701
A0A590UJR5
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 878 aa
97.8 kDa 		No 0
DLG1-242
ENSP00000499269
ENST00000659221
A0A0C4DFT3
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 892 aa
99.8 kDa 		No 0
DLG1-243
ENSP00000499602
ENST00000659716
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 871 aa
97.1 kDa 		No 0
DLG1-246
ENSP00000499559
ENST00000660553
A0A590UJR4
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0030054 [cell junction]
Show all
 819 aa
90.4 kDa 		No 0
DLG1-247
ENSP00000499363
ENST00000660898
A0A590UJD9
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 925 aa
103.2 kDa 		No 0
DLG1-248
ENSP00000499440
ENST00000661013
A0A0C4DFT3
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 892 aa
99.8 kDa 		No 0
DLG1-250
ENSP00000499229
ENST00000661336
A0A590UJ08
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 875 aa
98 kDa 		No 0
DLG1-252
ENSP00000499514
ENST00000661453
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 871 aa
97.1 kDa 		No 0
DLG1-253
ENSP00000499637
ENST00000661808
A0A590UJZ4
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 375 aa
40.5 kDa 		No 0
DLG1-254
ENSP00000499774
ENST00000662727
A0A590UKA8
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 883 aa
98.3 kDa 		No 0
DLG1-255
ENSP00000499384
ENST00000663148
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 871 aa
97.1 kDa 		No 0
DLG1-257
ENSP00000499250
ENST00000664991
A0A590UJ18
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 868 aa
96.6 kDa 		No 0
DLG1-259
ENSP00000499793
ENST00000666007
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 853 aa
95.2 kDa 		No 0
DLG1-260
ENSP00000499313
ENST00000667104
A0A590UJ68
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 865 aa
96.4 kDa 		No 0
DLG1-261
ENSP00000499414
ENST00000667157
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001657 [ureteric bud development]
GO:0001658 [branching involved in ureteric bud morphogenesis]
GO:0001771 [immunological synapse formation]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0002088 [lens development in camera-type eye]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005604 [basement membrane]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008104 [protein localization]
GO:0008283 [cell population proliferation]
GO:0008284 [positive regulation of cell population proliferation]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0019900 [kinase binding]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030041 [actin filament polymerization]
GO:0030054 [cell junction]
GO:0030432 [peristalsis]
GO:0030838 [positive regulation of actin filament polymerization]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031253 [cell projection membrane]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031579 [membrane raft organization]
GO:0031594 [neuromuscular junction]
GO:0031641 [regulation of myelination]
GO:0032147 [activation of protein kinase activity]
GO:0033268 [node of Ranvier]
GO:0035748 [myelin sheath abaxonal region]
GO:0042098 [T cell proliferation]
GO:0042110 [T cell activation]
GO:0042130 [negative regulation of T cell proliferation]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0042982 [amyloid precursor protein metabolic process]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043219 [lateral loop]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043491 [protein kinase B signaling]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045121 [membrane raft]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048608 [reproductive structure development]
GO:0048704 [embryonic skeletal system morphogenesis]
GO:0048729 [tissue morphogenesis]
GO:0048745 [smooth muscle tissue development]
GO:0050680 [negative regulation of epithelial cell proliferation]
GO:0051660 [establishment of centrosome localization]
GO:0051898 [negative regulation of protein kinase B signaling]
GO:0060022 [hard palate development]
GO:0060090 [molecular adaptor activity]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0098919 [structural constituent of postsynaptic density]
GO:0098978 [glutamatergic synapse]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 893 aa
99.9 kDa 		No 0
DLG1-262
ENSP00000499347
ENST00000667971
A0A590UJC5
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0030054 [cell junction]
Show all
 879 aa
98.4 kDa 		No 0
DLG1-265
ENSP00000499413
ENST00000669565
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 893 aa
99.9 kDa 		No 0
DLG1-268
ENSP00000499542
ENST00000670455
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 893 aa
99.9 kDa 		No 0
DLG1-269
ENSP00000499437
ENST00000670935
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 904 aa
100.5 kDa 		No 0
DLG1-270
ENSP00000499580
ENST00000671185
Q12959
[Direct mapping] Disks large homolog 1
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0001772 [immunological synapse]
GO:0001935 [endothelial cell proliferation]
GO:0004385 [guanylate kinase activity]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005923 [bicellular tight junction]
GO:0007015 [actin filament organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007268 [chemical synaptic transmission]
GO:0008022 [protein C-terminus binding]
GO:0008092 [cytoskeletal protein binding]
GO:0008360 [regulation of cell shape]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0014069 [postsynaptic density]
GO:0014704 [intercalated disc]
GO:0015459 [potassium channel regulator activity]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016324 [apical plasma membrane]
GO:0019901 [protein kinase binding]
GO:0019902 [phosphatase binding]
GO:0030054 [cell junction]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030953 [astral microtubule organization]
GO:0031434 [mitogen-activated protein kinase kinase binding]
GO:0031503 [protein-containing complex localization]
GO:0031594 [neuromuscular junction]
GO:0042383 [sarcolemma]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043268 [positive regulation of potassium ion transport]
GO:0043622 [cortical microtubule organization]
GO:0044325 [transmembrane transporter binding]
GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity]
GO:0045202 [synapse]
GO:0045296 [cadherin binding]
GO:0046037 [GMP metabolic process]
GO:0046710 [GDP metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051660 [establishment of centrosome localization]
GO:0070062 [extracellular exosome]
GO:0070161 [anchoring junction]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0097016 [L27 domain binding]
GO:0097025 [MPP7-DLG1-LIN7 complex]
GO:0097060 [synaptic membrane]
GO:0097120 [receptor localization to synapse]
GO:0098609 [cell-cell adhesion]
GO:0098839 [postsynaptic density membrane]
GO:0098911 [regulation of ventricular cardiac muscle cell action potential]
GO:0099562 [maintenance of postsynaptic density structure]
GO:0099645 [neurotransmitter receptor localization to postsynaptic specialization membrane]
GO:1902305 [regulation of sodium ion transmembrane transport]
GO:1902473 [regulation of protein localization to synapse]
GO:1903078 [positive regulation of protein localization to plasma membrane]
GO:1903286 [regulation of potassium ion import]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:1903760 [regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization]
GO:1903764 [regulation of potassium ion export across plasma membrane]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 871 aa
97.1 kDa 		No 0
DLG1-271
ENSP00000499692
ENST00000671246
A0A590UK48
[Direct mapping] Disks large homolog 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0030054 [cell junction]
Show all
 821 aa
90.6 kDa 		No 0

Contact

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The Human Protein Atlas

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