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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
113.1
nTPM
HPA:
45.3
nTPM
GTEx:
113.1
nTPM
FANTOM5:
98.2
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA050124
Antibody CAB004451
Cholangiocytes
Not detected
Low
Hepatocytes
Not detected
Low
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
45.3
Female, age 60
Liver sample 21 nTPM: 47.4
Male, age 54
Liver sample 23 nTPM: 77.4
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 39.6
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 28.6
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 31.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 41.7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 66.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 45.8
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 49.7
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 23.7
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
113.1
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 113.1
Samples: 226
Max nTPM: 433.2
Min nTPM: 31.8
Std nTPM: 67.8
Median nTPM: 93.0
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
433.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
405.3
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
396.7
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
393.4
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
374.2
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
330.2
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
309.9
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
286.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
272.7
GTEX-14PJO-1726-SM-68719
60-69 years, male
261.8
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
237.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
235.1
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
218.6
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
216.4
GTEX-REY6-1226-SM-48FDR
60-69 years, male
214.1
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
210.6
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
209.0
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
203.3
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
200.3
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
199.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
198.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
197.5
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
196.7
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
187.2
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
185.9
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
183.1
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
180.8
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
179.3
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
179.0
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
178.6
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
173.9
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
171.5
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
167.2
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
163.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
162.7
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
162.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
160.1
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
159.9
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
159.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
156.6
GTEX-O5YV-0726-SM-EV798
60-69 years, female
156.1
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
156.0
GTEX-12696-0826-SM-5EGGE
60-69 years, male
154.4
GTEX-14XAO-0226-SM-68728
60-69 years, female
153.5
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
152.2
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
150.5
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
149.3
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
149.3
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
147.6
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
145.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
143.1
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
143.0
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
142.3
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
141.1
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
137.9
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
137.8
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
137.8
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
137.6
GTEX-18A66-2026-SM-7189C
60-69 years, male
133.1
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
130.6
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
129.4
GTEX-13113-1326-SM-5GCOI
60-69 years, female
128.5
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
127.7
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
127.2
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
126.2
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
124.3
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
123.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
121.9
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
121.6
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
120.8
GTEX-X261-1726-SM-4PQYT
50-59 years, male
119.5
GTEX-S33H-1626-SM-4AD68
30-39 years, male
118.9
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
117.7
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
116.9
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
115.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
115.4
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
115.2
GTEX-S32W-1926-SM-4AD63
50-59 years, female
114.9
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
114.3
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
114.1
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
112.8
GTEX-RU72-1426-SM-46MUF
50-59 years, female
112.7
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
112.6
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
112.2
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
111.2
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
110.8
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
110.1
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
108.2
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
108.1
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
108.0
GTEX-14PHX-0526-SM-664NW
50-59 years, male
107.5
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
106.7
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
106.0
GTEX-YECK-1926-SM-4W21H
60-69 years, male
105.8
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
104.9
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
104.5
GTEX-1B932-1426-SM-793AN
40-49 years, female
103.5
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
101.7
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
101.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
100.0
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
99.9
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
97.8
GTEX-QEL4-1226-SM-447A4
50-59 years, male
97.3
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
95.5
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
95.3
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
95.0
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
95.0
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
93.7
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
93.7
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
93.6
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
93.3
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
93.2
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
93.1
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
93.0
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
92.8
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
92.4
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
91.5
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
90.3
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
90.0
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
88.8
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
88.6
GTEX-11ZUS-2526-SM-59872
30-39 years, male
88.5
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
88.2
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
88.1
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
88.1
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
87.7
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
86.9
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
86.6
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
85.8
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
85.7
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
85.2
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
85.0
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
84.8
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
84.8
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
84.2
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
83.9
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
83.8
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
83.7
GTEX-1399T-0826-SM-5IFES
60-69 years, male
83.6
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
83.5
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
83.2
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
82.8
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
82.7
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
82.7
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
82.3
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
82.2
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
81.7
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
81.6
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
81.2
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
80.9
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
78.7
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
76.3
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
76.2
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
75.6
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
75.0
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
74.9
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
74.2
GTEX-Q734-0326-SM-48U15
40-49 years, female
73.5
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
73.1
GTEX-QESD-2026-SM-447BI
20-29 years, male
72.4
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
71.7
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
71.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
70.9
GTEX-11GSP-0626-SM-5986T
60-69 years, female
70.8
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
70.8
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
70.5
GTEX-17F96-1226-SM-79OK2
70-79 years, male
70.4
GTEX-P78B-1326-SM-3P611
40-49 years, female
69.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
69.8
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
68.4
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
68.2
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
67.3
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
67.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
66.7
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
66.1
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
65.6
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
65.1
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
65.0
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
65.0
GTEX-144GL-1426-SM-79OMA
50-59 years, male
64.9
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
64.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
64.4
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
64.1
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
63.2
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
62.8
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
62.3
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
61.8
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
61.7
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
61.6
GTEX-1B933-1226-SM-731DW
50-59 years, female
61.3
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
61.3
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
59.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
58.5
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
58.3
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
58.0
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
57.7
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
57.5
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
57.5
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
57.4
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
57.3
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
57.2
GTEX-14E7W-1526-SM-6871X
70-79 years, male
56.8
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
56.2
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
55.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
55.1
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
54.6
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
53.8
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
53.4
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
53.1
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
52.9
GTEX-18465-1626-SM-7LG6N
50-59 years, male
52.3
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
51.8
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
50.1
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
49.7
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
48.8
GTEX-14JG1-1626-SM-664NH
40-49 years, male
48.8
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
48.6
GTEX-R53T-0326-SM-48FEC
50-59 years, female
47.6
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
47.1
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
42.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
41.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
40.2
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
39.3
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
35.1
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
34.8
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
31.8
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
