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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:86.7 nTPM
HPA Brain:78.2 nTPM
GTEx:86.7 nTPM
FANTOM5:57.1 Scaled Tags Per Million
Pig:32.6 nTPM
Mouse:124.8 nTPM
Allen mouse:2.1 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

78.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 45.3
2019 Male, age 18, unknown 71.2
1833 Male, age 53, unknown 63.7
2666 Male, age 74, left hemisphere 52.9
1870 Female, age 42, unknown 50.6
1830 Male, age 51, unknown 49.0
2219 Male, age 76, both hemispheres 45.3
2828 Female, age 72, unknown 41.9
2411 Female, age 72, unknown 36.2
1827 Male, age 72, unknown 35.3
2586 Male, age 75, left hemisphere 7.2
Dorsal raphe nucleus
nTPM: 40.2
2750 Male, age 76, both hemispheres 51.7
2016 Female, age 72, unknown 42.0
2298 Female, age 72, unknown 40.8
1828 Male, age 53, unknown 38.9
2047 Male, age 72, unknown 27.5
Inferior colliculus
nTPM: 44.7
2097 Female, age 72, unknown 59.2
1848 Female, age 42, unknown 44.4
1890 Male, age 53, unknown 43.9
2849 Male, age 72, unknown 31.4
Median raphe nucleus
nTPM: 34.1
2220 Male, age 76, midline 34.1
Periaquaductal grey, anterior
nTPM: 42.5
2502 Female, age 75, unknown 70.0
1947 Male, age 18, unknown 35.5
1795 Male, age 51, unknown 22.0
Periaquaductal grey, dorsal
nTPM: 31.1
2464 Female, age 72, unknown 45.5
1831 Male, age 72, unknown 33.8
2850 Male, age 76, both hemispheres 25.2
1840 Male, age 53, unknown 19.9
Periaquaductal grey, lateral
nTPM: 32.1
2272 Male, age 74, both hemispheres 40.9
2053 Male, age 18, unknown 34.6
2140 Male, age 76, both hemispheres 20.7
Pretectal area
nTPM: 44.4
1817 Female, age 42, unknown 66.9
2007 Male, age 72, unknown 60.5
1815 Male, age 53, unknown 54.4
1944 Female, age 72, unknown 52.5
1816 Male, age 51, unknown 47.9
2667 Female, age 75, unknown 46.4
2316 Male, age 76, right hemisphere 43.0
2273 Male, age 74, both hemispheres 36.7
2224 Female, age 72, unknown 36.2
2825 Male, age 18, unknown 27.0
2407 Male, age 75, both hemispheres 16.3
Red nucleus
nTPM: 78.2
1954 Female, age 42, unknown 129.3
1904 Male, age 53, unknown 120.5
1821 Female, age 72, unknown 111.1
2823 Male, age 76, right hemisphere 111.1
2503 Female, age 72, unknown 92.4
1865 Male, age 51, unknown 86.5
2785 Male, age 18, unknown 69.0
2227 Male, age 72, unknown 68.1
2769 Male, age 72, unknown 66.2
2725 Female, age 75, unknown 32.4
2588 Male, age 74, left hemisphere 30.2
2584 Male, age 75, left hemisphere 21.5
Substantia nigra
nTPM: 41.5
2665 Male, age 74, both hemispheres 81.9
1889 Female, age 72, unknown 52.1
2241 Male, age 72, unknown 51.6
1851 Male, age 51, unknown 38.3
2409 Female, age 72, unknown 37.5
2590 Female, age 75, unknown 35.7
1916 Female, age 42, unknown 33.6
1941 Male, age 53, unknown 33.5
2699 Male, age 18, unknown 29.0
2583 Male, age 75, right hemisphere 21.3
Superior colliculus
nTPM: 42.4
1895 Male, age 76, right hemisphere 67.5
1913 Female, age 42, unknown 55.3
2087 Female, age 72, unknown 55.0
2587 Male, age 74, left hemisphere 44.4
2668 Female, age 75, unknown 43.3
2261 Male, age 18, unknown 42.5
1995 Male, age 72, unknown 41.4
1839 Male, age 51, unknown 39.3
1796 Male, age 53, unknown 25.6
2664 Male, age 75, both hemispheres 10.1
Ventral tegmental area
nTPM: 35.6
2410 Female, age 72, unknown 45.5
2223 Female, age 72, unknown 41.0
2218 Male, age 76, both hemispheres 35.3
1942 Male, age 51, unknown 33.8
1915 Female, age 42, unknown 33.2
2021 Male, age 53, unknown 24.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

86.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 86.7
Samples: 139

Max nTPM: 273.8
Min nTPM: 17.9
Std nTPM: 44.4
Median nTPM: 73.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 273.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 233.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 209.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 190.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 190.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 188.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 173.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 167.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 165.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 165.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 160.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 156.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 155.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 153.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 147.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 142.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 141.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 140.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 136.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 136.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 130.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 128.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 127.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 126.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 123.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 123.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 122.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 120.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 119.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 119.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 118.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 115.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 113.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 111.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 110.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 108.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 107.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 107.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 107.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 106.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 105.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 103.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 101.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 96.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 95.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 95.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 92.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 91.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 90.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 90.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 87.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 87.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 86.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 81.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 81.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 81.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 80.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 78.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 77.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 77.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 77.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 77.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 76.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 75.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 75.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 75.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 75.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 75.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 75.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 73.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 73.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 73.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 71.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 71.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 70.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 69.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 69.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 69.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 68.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 68.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 68.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 67.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 66.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 66.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 66.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 65.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 65.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 64.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 64.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 63.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 63.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 62.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 62.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 62.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 62.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 60.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 60.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 60.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 59.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 58.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 58.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 57.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 57.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 57.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 56.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 56.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 56.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 55.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 54.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 53.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 53.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 51.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 51.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 51.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 50.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 50.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 49.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 49.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 48.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 48.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 47.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 45.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 44.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 43.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 43.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 43.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 41.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 39.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 39.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 38.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 37.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 37.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 34.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 33.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 30.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 29.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 27.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 24.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 17.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

57.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 57.1
FF:10158-103A5 76 years, female 57.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

32.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 32.6
Samples: 4

Max nTPM: 41.2
Min nTPM: 28.4
Sample A Female 41.2
Sample B Female 32.0
Sample C Male 28.7
Sample D Male 28.4
Midbrain
nTPM: 26.9
Samples: 4

Max nTPM: 30.8
Min nTPM: 24.2
Sample A Female 28.3
Sample B Female 30.8
Sample C Male 24.3
Sample D Male 24.2
Periaqueductal gray
nTPM: 27.1
Samples: 3

Max nTPM: 27.5
Min nTPM: 26.7
Sample B Female 27.5
Sample C Male 26.7
Sample D Male 27.2
Superior colliculi
nTPM: 31.5
Samples: 4

Max nTPM: 39.8
Min nTPM: 21.2
Sample A Female 33.2
Sample B Female 21.2
Sample C Male 31.8
Sample D Male 39.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

124.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 124.8
Samples: 4

Max nTPM: 132.5
Min nTPM: 119.4
Sample A Male 132.5
Sample B Male 126.9
Sample C Female 119.4
Sample D Female 120.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.1
74881146 Antisense, RP_060220_01_A04, Mouse strain C57BL/6J (56 days, male) 2.8
69549248 Antisense, RP_050125_01_C03, Mouse strain C57BL/6J (56 days, male) 1.4

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