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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
110.5
nTPM
HPA:
48.8
nTPM
GTEx:
110.5
nTPM
FANTOM5:
205.9
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA038621
Antibody HPA038622
Cholangiocytes
Low
Not detected
Hepatocytes
Medium
Low
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
48.8
Female, age 60
Liver sample 21 nTPM: 74.4
Male, age 54
Liver sample 23 nTPM: 51.2
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 68.7
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 15.9
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 19.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 45.6
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 34.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 77.8
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 36.6
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 63.3
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
110.5
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 110.5
Samples: 226
Max nTPM: 249.7
Min nTPM: 43.6
Std nTPM: 27.9
Median nTPM: 108.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
249.7
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
200.6
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
185.7
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
181.4
GTEX-REY6-1226-SM-48FDR
60-69 years, male
174.9
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
174.6
GTEX-14JG1-1626-SM-664NH
40-49 years, male
172.0
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
171.7
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
163.2
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
162.7
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
161.6
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
151.2
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
149.4
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
148.3
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
144.6
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
143.9
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
143.4
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
143.1
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
143.0
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
142.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
142.7
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
142.5
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
141.8
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
141.7
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
140.6
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
140.4
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
140.3
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
139.8
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
138.7
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
138.3
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
137.7
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
137.6
GTEX-RN64-1826-SM-48FDV
50-59 years, male
137.2
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
137.0
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
136.6
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
136.5
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
135.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
135.6
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
135.3
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
135.3
GTEX-18A7A-1526-SM-72D69
50-59 years, female
135.1
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
134.9
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
134.5
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
133.9
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
133.7
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
133.5
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
132.5
GTEX-YECK-1926-SM-4W21H
60-69 years, male
132.5
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
132.1
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
131.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
131.3
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
130.5
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
130.0
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
129.4
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
129.2
GTEX-X261-1726-SM-4PQYT
50-59 years, male
127.9
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
127.8
GTEX-14E7W-1526-SM-6871X
70-79 years, male
127.1
GTEX-144GL-1426-SM-79OMA
50-59 years, male
126.9
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
126.5
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
125.6
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
124.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
124.3
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
124.3
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
124.1
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
123.6
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
123.5
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
122.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
121.4
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
121.0
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
120.6
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
120.5
GTEX-RU72-1426-SM-46MUF
50-59 years, female
120.3
GTEX-12696-0826-SM-5EGGE
60-69 years, male
119.2
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
119.1
GTEX-P78B-1326-SM-3P611
40-49 years, female
118.9
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
118.6
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
118.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
118.3
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
117.7
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
117.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
117.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
117.3
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
117.0
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
116.6
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
116.4
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
115.7
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
115.7
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
115.4
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
115.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
115.1
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
114.8
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
114.7
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
114.4
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
114.3
GTEX-13113-1326-SM-5GCOI
60-69 years, female
113.7
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
112.9
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
112.5
GTEX-14PJO-1726-SM-68719
60-69 years, male
112.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
112.3
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
112.2
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
112.2
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
111.4
GTEX-13112-1426-SM-5EGH8
50-59 years, male
111.3
GTEX-1399T-0826-SM-5IFES
60-69 years, male
111.1
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
110.7
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
110.4
GTEX-R53T-0326-SM-48FEC
50-59 years, female
109.6
GTEX-1B933-1226-SM-731DW
50-59 years, female
109.3
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
109.1
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
108.8
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
108.7
GTEX-S32W-1926-SM-4AD63
50-59 years, female
108.7
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
108.3
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
108.3
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
108.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
108.0
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
107.9
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
106.9
GTEX-1B932-1426-SM-793AN
40-49 years, female
106.7
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
106.5
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
106.4
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
106.3
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
106.1
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
106.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
105.7
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
105.2
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
105.0
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
104.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
104.8
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
104.6
GTEX-17HHE-0126-SM-79398
50-59 years, male
104.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
103.9
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
103.8
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
103.8
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
103.2
GTEX-14XAO-0226-SM-68728
60-69 years, female
103.1
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
103.0
GTEX-14PHX-0526-SM-664NW
50-59 years, male
102.8
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
102.7
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
102.5
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
102.0
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
102.0
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
101.9
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
101.3
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
101.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
100.9
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
100.9
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
100.8
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
100.8
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
99.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
99.6
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
99.5
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
99.0
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
98.8
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
98.4
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
98.0
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
97.8
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
97.8
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
95.6
GTEX-18465-1626-SM-7LG6N
50-59 years, male
95.5
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
95.0
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
94.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
94.1
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
93.9
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
93.9
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
93.8
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
93.8
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
93.6
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
93.6
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
93.3
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
92.8
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
91.7
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
91.5
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
91.5
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
91.2
GTEX-Q734-0326-SM-48U15
40-49 years, female
91.1
GTEX-17F96-1226-SM-79OK2
70-79 years, male
90.3
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
90.3
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
88.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
87.6
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
87.5
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
86.4
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
86.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
85.8
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
85.7
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
85.7
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
85.0
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
84.9
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
83.9
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
83.9
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
83.3
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
83.3
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
83.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
83.1
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
81.4
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
80.9
GTEX-QEL4-1226-SM-447A4
50-59 years, male
80.4
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
80.0
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
79.4
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
78.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
78.5
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
78.4
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
77.8
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
77.2
GTEX-18A66-2026-SM-7189C
60-69 years, male
76.6
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
76.1
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
73.8
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
72.8
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
70.4
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
70.2
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
68.4
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
67.9
GTEX-11GSP-0626-SM-5986T
60-69 years, female
67.5
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
67.0
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
66.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
64.0
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
62.8
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
62.0
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
60.2
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
57.5
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
57.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
52.5
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
52.4
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
52.3
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
43.6
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
