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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:81.2 nTPM
HPA Brain:52.5 nTPM
GTEx:81.2 nTPM
FANTOM5:228.4 Scaled Tags Per Million
Pig:86.3 nTPM
Mouse:75.6 nTPM
Allen mouse:1.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

52.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 44.6
2411 Female, age 72, unknown 57.1
1830 Male, age 51, unknown 55.9
1833 Male, age 53, unknown 50.6
1870 Female, age 42, unknown 49.5
2828 Female, age 72, unknown 49.2
1827 Male, age 72, unknown 43.9
2219 Male, age 76, both hemispheres 37.1
2586 Male, age 75, left hemisphere 34.8
2019 Male, age 18, unknown 34.0
2666 Male, age 74, left hemisphere 33.9
Dorsal raphe nucleus
nTPM: 48.1
2750 Male, age 76, both hemispheres 62.6
2298 Female, age 72, unknown 50.4
2047 Male, age 72, unknown 46.1
1828 Male, age 53, unknown 41.4
2016 Female, age 72, unknown 39.9
Inferior colliculus
nTPM: 41.4
2849 Male, age 72, unknown 48.7
1848 Female, age 42, unknown 45.6
1890 Male, age 53, unknown 36.2
2097 Female, age 72, unknown 35.0
Median raphe nucleus
nTPM: 52.5
2220 Male, age 76, midline 52.5
Periaquaductal grey, anterior
nTPM: 44.2
1947 Male, age 18, unknown 48.4
1795 Male, age 51, unknown 43.2
2502 Female, age 75, unknown 40.9
Periaquaductal grey, dorsal
nTPM: 40.2
2464 Female, age 72, unknown 45.5
2850 Male, age 76, both hemispheres 39.9
1831 Male, age 72, unknown 38.6
1840 Male, age 53, unknown 37.0
Periaquaductal grey, lateral
nTPM: 44.2
2053 Male, age 18, unknown 44.5
2272 Male, age 74, both hemispheres 44.1
2140 Male, age 76, both hemispheres 43.8
Pretectal area
nTPM: 43.1
2667 Female, age 75, unknown 53.6
2273 Male, age 74, both hemispheres 52.7
2316 Male, age 76, right hemisphere 50.6
2825 Male, age 18, unknown 49.3
2224 Female, age 72, unknown 46.7
2407 Male, age 75, both hemispheres 42.0
1815 Male, age 53, unknown 41.5
1817 Female, age 42, unknown 36.9
2007 Male, age 72, unknown 35.4
1944 Female, age 72, unknown 35.0
1816 Male, age 51, unknown 30.4
Red nucleus
nTPM: 43.2
1865 Male, age 51, unknown 53.7
2503 Female, age 72, unknown 46.3
1821 Female, age 72, unknown 46.1
1954 Female, age 42, unknown 45.8
2769 Male, age 72, unknown 45.8
2227 Male, age 72, unknown 44.7
2823 Male, age 76, right hemisphere 42.9
2725 Female, age 75, unknown 42.2
2588 Male, age 74, left hemisphere 41.3
1904 Male, age 53, unknown 39.7
2785 Male, age 18, unknown 39.4
2584 Male, age 75, left hemisphere 31.0
Substantia nigra
nTPM: 36.1
1941 Male, age 53, unknown 44.1
2699 Male, age 18, unknown 42.4
1916 Female, age 42, unknown 40.1
1851 Male, age 51, unknown 35.2
2583 Male, age 75, right hemisphere 35.1
2409 Female, age 72, unknown 33.4
2665 Male, age 74, both hemispheres 32.9
1889 Female, age 72, unknown 32.8
2590 Female, age 75, unknown 32.8
2241 Male, age 72, unknown 32.7
Superior colliculus
nTPM: 43.7
1913 Female, age 42, unknown 50.4
1839 Male, age 51, unknown 46.6
1995 Male, age 72, unknown 46.2
1895 Male, age 76, right hemisphere 45.3
1796 Male, age 53, unknown 45.1
2587 Male, age 74, left hemisphere 45.0
2668 Female, age 75, unknown 41.3
2087 Female, age 72, unknown 41.0
2261 Male, age 18, unknown 40.2
2664 Male, age 75, both hemispheres 35.5
Ventral tegmental area
nTPM: 45.8
2223 Female, age 72, unknown 56.7
2218 Male, age 76, both hemispheres 48.8
2021 Male, age 53, unknown 47.8
2410 Female, age 72, unknown 46.4
1942 Male, age 51, unknown 38.4
1915 Female, age 42, unknown 36.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

81.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 81.2
Samples: 139

Max nTPM: 160.3
Min nTPM: 41.7
Std nTPM: 22.4
Median nTPM: 76.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 160.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 142.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 141.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 133.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 126.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 124.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 122.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 122.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 122.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 121.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 121.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 120.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 116.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 116.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 111.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 111.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 110.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 109.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 108.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 108.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 106.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 105.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 104.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 103.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 102.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 101.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 100.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 100.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 99.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 97.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 97.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 97.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 97.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 96.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 96.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 95.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 95.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 94.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 94.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 93.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 91.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 90.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 88.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 88.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 87.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 86.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 86.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 84.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 83.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 83.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 83.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 82.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 81.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 81.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 81.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 79.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 79.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 79.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 79.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 78.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 78.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 78.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 78.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 78.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 77.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 77.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 77.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 76.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 76.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 76.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 76.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 76.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 75.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 74.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 74.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 73.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 72.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 72.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 72.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 72.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 72.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 72.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 70.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 70.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 70.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 70.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 70.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 69.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 69.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 69.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 69.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 69.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 69.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 69.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 68.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 68.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 68.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 67.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 67.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 66.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 66.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 66.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 65.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 65.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 64.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 64.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 64.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 63.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 63.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 63.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 63.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 63.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 62.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 61.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 61.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 60.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 60.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 60.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 59.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 59.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 58.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 58.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 58.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 57.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 56.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 55.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 55.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 55.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 55.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 54.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 54.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 54.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 53.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 52.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 51.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 48.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 46.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 44.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 41.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

228.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 228.4
FF:10158-103A5 76 years, female 228.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

86.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 72.7
Samples: 4

Max nTPM: 100.3
Min nTPM: 54.3
Sample A Female 100.3
Sample B Female 54.3
Sample C Male 76.7
Sample D Male 59.3
Midbrain
nTPM: 86.3
Samples: 4

Max nTPM: 152.2
Min nTPM: 54.0
Sample A Female 152.2
Sample B Female 84.0
Sample C Male 54.0
Sample D Male 55.1
Periaqueductal gray
nTPM: 75.7
Samples: 3

Max nTPM: 82.0
Min nTPM: 66.8
Sample B Female 78.3
Sample C Male 82.0
Sample D Male 66.8
Superior colliculi
nTPM: 62.4
Samples: 4

Max nTPM: 73.3
Min nTPM: 53.9
Sample A Female 73.3
Sample B Female 53.9
Sample C Male 60.4
Sample D Male 61.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

75.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 75.6
Samples: 4

Max nTPM: 80.0
Min nTPM: 69.9
Sample A Male 80.0
Sample B Male 76.2
Sample C Female 69.9
Sample D Female 76.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.5
75041432 Antisense, RP_060412_04_B02, Mouse strain C57BL/6J (56 days, male) 2.3
71232692 Antisense, RP_050428_03_F10, Mouse strain C57BL/6J (56 days, male) 0.7

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