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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:9.5 nTPM
HPA Brain:81.6 nTPM
GTEx:9.5 nTPM
FANTOM5:49.5 Scaled Tags Per Million
Pig:96.1 nTPM
Mouse:54.5 nTPM
Allen mouse:7.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

81.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 62.4
2219 Male, age 76, both hemispheres 78.7
2666 Male, age 74, left hemisphere 72.0
2586 Male, age 75, left hemisphere 71.7
1827 Male, age 72, unknown 70.0
2828 Female, age 72, unknown 59.9
2411 Female, age 72, unknown 58.8
1833 Male, age 53, unknown 58.6
1830 Male, age 51, unknown 53.2
1870 Female, age 42, unknown 51.2
2019 Male, age 18, unknown 50.4
Dorsal raphe nucleus
nTPM: 59.5
2047 Male, age 72, unknown 64.9
2750 Male, age 76, both hemispheres 63.1
2298 Female, age 72, unknown 58.0
1828 Male, age 53, unknown 57.1
2016 Female, age 72, unknown 54.5
Inferior colliculus
nTPM: 62.2
2849 Male, age 72, unknown 66.5
1848 Female, age 42, unknown 65.3
2097 Female, age 72, unknown 60.6
1890 Male, age 53, unknown 56.2
Median raphe nucleus
nTPM: 81.6
2220 Male, age 76, midline 81.6
Periaquaductal grey, anterior
nTPM: 69.4
1947 Male, age 18, unknown 74.7
1795 Male, age 51, unknown 69.8
2502 Female, age 75, unknown 63.8
Periaquaductal grey, dorsal
nTPM: 58.4
2850 Male, age 76, both hemispheres 61.9
1831 Male, age 72, unknown 58.7
1840 Male, age 53, unknown 57.2
2464 Female, age 72, unknown 56.0
Periaquaductal grey, lateral
nTPM: 55.3
2272 Male, age 74, both hemispheres 56.0
2140 Male, age 76, both hemispheres 55.1
2053 Male, age 18, unknown 54.6
Pretectal area
nTPM: 61.6
1816 Male, age 51, unknown 74.2
1817 Female, age 42, unknown 71.6
2007 Male, age 72, unknown 68.6
1815 Male, age 53, unknown 68.0
2667 Female, age 75, unknown 67.0
2825 Male, age 18, unknown 64.5
1944 Female, age 72, unknown 61.6
2224 Female, age 72, unknown 60.6
2407 Male, age 75, both hemispheres 48.3
2316 Male, age 76, right hemisphere 48.0
2273 Male, age 74, both hemispheres 44.8
Red nucleus
nTPM: 53.9
2588 Male, age 74, left hemisphere 64.5
2503 Female, age 72, unknown 60.4
2584 Male, age 75, left hemisphere 60.0
2725 Female, age 75, unknown 58.2
1821 Female, age 72, unknown 57.7
1954 Female, age 42, unknown 53.3
2227 Male, age 72, unknown 50.9
2785 Male, age 18, unknown 50.8
1865 Male, age 51, unknown 49.3
2769 Male, age 72, unknown 47.7
1904 Male, age 53, unknown 47.3
2823 Male, age 76, right hemisphere 47.0
Substantia nigra
nTPM: 66.7
1916 Female, age 42, unknown 92.3
1941 Male, age 53, unknown 74.7
2665 Male, age 74, both hemispheres 74.4
2241 Male, age 72, unknown 69.4
1851 Male, age 51, unknown 67.4
2699 Male, age 18, unknown 66.4
1889 Female, age 72, unknown 65.3
2590 Female, age 75, unknown 60.0
2583 Male, age 75, right hemisphere 57.8
2409 Female, age 72, unknown 39.2
Superior colliculus
nTPM: 59.5
2664 Male, age 75, both hemispheres 71.2
1796 Male, age 53, unknown 68.0
2261 Male, age 18, unknown 66.2
2087 Female, age 72, unknown 64.7
1839 Male, age 51, unknown 63.3
1895 Male, age 76, right hemisphere 58.5
2668 Female, age 75, unknown 58.3
2587 Male, age 74, left hemisphere 52.9
1913 Female, age 42, unknown 48.3
1995 Male, age 72, unknown 43.5
Ventral tegmental area
nTPM: 65.8
2218 Male, age 76, both hemispheres 84.4
1915 Female, age 42, unknown 67.1
2410 Female, age 72, unknown 63.2
2021 Male, age 53, unknown 61.7
1942 Male, age 51, unknown 60.4
2223 Female, age 72, unknown 57.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

9.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 9.5
Samples: 139

Max nTPM: 24.8
Min nTPM: 5.2
Std nTPM: 3.4
Median nTPM: 8.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 24.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 23.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 21.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 19.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 17.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 16.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 16.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 15.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 15.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 15.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 14.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 14.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 14.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 13.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 13.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 13.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 13.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 13.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 12.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 12.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 12.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 12.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 12.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 12.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 12.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 12.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 12.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 11.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 11.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 11.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 11.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 11.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 11.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 11.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 10.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 10.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 10.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 10.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 10.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 10.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 10.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 10.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 10.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 10.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 10.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 10.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 10.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 9.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 9.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 9.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 9.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 9.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 9.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 9.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 9.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 9.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 9.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 9.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 9.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 9.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 8.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 8.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 8.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 8.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 8.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 8.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 8.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 8.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 8.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 8.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 8.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 8.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 8.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 8.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 8.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 8.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 8.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 8.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 8.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 7.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 7.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 7.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 7.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 7.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 7.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 7.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 7.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 7.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 7.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 7.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 7.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 7.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 7.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 7.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 7.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 7.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 7.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 7.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 7.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 7.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 7.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 7.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 7.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 7.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 6.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 6.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 6.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 6.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 6.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 6.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 6.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 6.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 6.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 6.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 6.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 6.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 6.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 6.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 6.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 6.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 6.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 6.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 6.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 6.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 6.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 6.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 6.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 6.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 6.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 6.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 6.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 6.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 6.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 5.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 5.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 5.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 5.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 5.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 5.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

49.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 49.5
FF:10158-103A5 76 years, female 49.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

96.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 96.1
Samples: 4

Max nTPM: 124.1
Min nTPM: 67.5
Sample A Female 111.8
Sample B Female 81.1
Sample C Male 124.1
Sample D Male 67.5
Midbrain
nTPM: 95.5
Samples: 4

Max nTPM: 127.1
Min nTPM: 69.9
Sample A Female 69.9
Sample B Female 86.7
Sample C Male 127.1
Sample D Male 98.4
Periaqueductal gray
nTPM: 87.2
Samples: 3

Max nTPM: 100.9
Min nTPM: 79.5
Sample B Female 81.2
Sample C Male 100.9
Sample D Male 79.5
Superior colliculi
nTPM: 87.4
Samples: 4

Max nTPM: 105.5
Min nTPM: 65.8
Sample A Female 86.7
Sample B Female 65.8
Sample C Male 105.5
Sample D Male 91.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

54.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 54.5
Samples: 4

Max nTPM: 58.5
Min nTPM: 44.8
Sample A Male 44.8
Sample B Male 56.9
Sample C Female 58.5
Sample D Female 57.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.6
68269508 Antisense, RP_041129_01_F12, Mouse strain C57BL/6J (56 days, male) 7.6

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