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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:12.2 nTPM
HPA Brain:61.1 nTPM
GTEx:12.2 nTPM
FANTOM5:31.1 Scaled Tags Per Million
Pig:25.4 nTPM
Mouse:27.1 nTPM
Allen mouse:9.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

61.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 39.4
2219 Male, age 76, both hemispheres 52.5
2586 Male, age 75, left hemisphere 46.5
2666 Male, age 74, left hemisphere 45.9
2411 Female, age 72, unknown 38.3
2828 Female, age 72, unknown 38.0
1827 Male, age 72, unknown 36.8
1833 Male, age 53, unknown 36.8
1830 Male, age 51, unknown 34.2
1870 Female, age 42, unknown 32.4
2019 Male, age 18, unknown 32.2
Dorsal raphe nucleus
nTPM: 40.0
2047 Male, age 72, unknown 44.5
1828 Male, age 53, unknown 42.0
2750 Male, age 76, both hemispheres 41.4
2298 Female, age 72, unknown 37.8
2016 Female, age 72, unknown 34.3
Inferior colliculus
nTPM: 30.8
1890 Male, age 53, unknown 32.4
2849 Male, age 72, unknown 32.4
1848 Female, age 42, unknown 30.6
2097 Female, age 72, unknown 27.7
Median raphe nucleus
nTPM: 47.3
2220 Male, age 76, midline 47.3
Periaquaductal grey, anterior
nTPM: 38.4
1947 Male, age 18, unknown 39.8
1795 Male, age 51, unknown 39.5
2502 Female, age 75, unknown 35.9
Periaquaductal grey, dorsal
nTPM: 31.2
1840 Male, age 53, unknown 35.2
2850 Male, age 76, both hemispheres 31.0
2464 Female, age 72, unknown 30.5
1831 Male, age 72, unknown 28.1
Periaquaductal grey, lateral
nTPM: 30.4
2053 Male, age 18, unknown 33.0
2140 Male, age 76, both hemispheres 31.5
2272 Male, age 74, both hemispheres 26.8
Pretectal area
nTPM: 32.8
2007 Male, age 72, unknown 38.6
2667 Female, age 75, unknown 35.6
2825 Male, age 18, unknown 35.5
1815 Male, age 53, unknown 34.9
2224 Female, age 72, unknown 34.9
1817 Female, age 42, unknown 34.7
1944 Female, age 72, unknown 32.8
1816 Male, age 51, unknown 32.1
2407 Male, age 75, both hemispheres 29.2
2316 Male, age 76, right hemisphere 29.1
2273 Male, age 74, both hemispheres 23.2
Red nucleus
nTPM: 36.3
2584 Male, age 75, left hemisphere 43.7
2588 Male, age 74, left hemisphere 39.7
1821 Female, age 72, unknown 39.0
2823 Male, age 76, right hemisphere 38.6
2725 Female, age 75, unknown 37.8
2769 Male, age 72, unknown 36.8
2227 Male, age 72, unknown 36.4
1904 Male, age 53, unknown 35.3
1954 Female, age 42, unknown 33.5
2503 Female, age 72, unknown 32.6
1865 Male, age 51, unknown 31.1
2785 Male, age 18, unknown 30.8
Substantia nigra
nTPM: 61.1
1916 Female, age 42, unknown 95.1
1851 Male, age 51, unknown 74.8
2665 Male, age 74, both hemispheres 70.8
2699 Male, age 18, unknown 70.2
2241 Male, age 72, unknown 66.6
2409 Female, age 72, unknown 54.6
1941 Male, age 53, unknown 53.6
2583 Male, age 75, right hemisphere 46.0
1889 Female, age 72, unknown 40.8
2590 Female, age 75, unknown 38.8
Superior colliculus
nTPM: 31.7
2668 Female, age 75, unknown 44.2
2664 Male, age 75, both hemispheres 36.5
1796 Male, age 53, unknown 35.3
1839 Male, age 51, unknown 33.0
1895 Male, age 76, right hemisphere 31.3
2587 Male, age 74, left hemisphere 30.1
2087 Female, age 72, unknown 30.0
2261 Male, age 18, unknown 30.0
1913 Female, age 42, unknown 24.5
1995 Male, age 72, unknown 22.3
Ventral tegmental area
nTPM: 51.2
2218 Male, age 76, both hemispheres 60.5
1915 Female, age 42, unknown 60.2
2410 Female, age 72, unknown 59.0
1942 Male, age 51, unknown 48.5
2223 Female, age 72, unknown 39.6
2021 Male, age 53, unknown 39.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

12.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 12.2
Samples: 139

Max nTPM: 29.8
Min nTPM: 3.9
Std nTPM: 5.4
Median nTPM: 10.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 29.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 27.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 24.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 24.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 24.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 23.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 23.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 23.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 23.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 22.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 21.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 21.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 20.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 20.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 19.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 19.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 19.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 19.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 19.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 18.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 18.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 18.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 18.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 18.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 18.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 17.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 17.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 16.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 16.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 16.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 15.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 15.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 15.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 15.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 15.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 15.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 15.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 15.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 14.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 14.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 14.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 13.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 13.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 13.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 13.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 13.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 13.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 13.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 13.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 13.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 13.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 13.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 12.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 12.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 12.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 12.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 12.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 12.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 12.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 11.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 11.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 11.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 11.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 11.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 11.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 11.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 11.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 11.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 10.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 10.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 10.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 10.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 10.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 10.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 10.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 10.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 9.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 9.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 9.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 9.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 9.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 9.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 9.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 9.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 9.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 9.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 9.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 9.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 9.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 8.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 8.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 8.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 8.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 8.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 8.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 8.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 8.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 8.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 8.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 8.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 8.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 8.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 8.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 8.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 8.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 7.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 7.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 7.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 7.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 7.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 7.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 7.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 7.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 7.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 7.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 7.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 7.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 7.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 7.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 6.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 6.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 6.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 6.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 6.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 6.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 6.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 6.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 6.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 6.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 6.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 6.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 6.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 5.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 5.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 5.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 5.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 4.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 4.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

31.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 31.1
FF:10158-103A5 76 years, female 31.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

25.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 25.4
Samples: 4

Max nTPM: 36.1
Min nTPM: 16.9
Sample A Female 28.1
Sample B Female 20.5
Sample C Male 36.1
Sample D Male 16.9
Midbrain
nTPM: 21.6
Samples: 4

Max nTPM: 25.2
Min nTPM: 15.2
Sample A Female 15.2
Sample B Female 23.2
Sample C Male 22.8
Sample D Male 25.2
Periaqueductal gray
nTPM: 22.3
Samples: 3

Max nTPM: 26.5
Min nTPM: 17.7
Sample B Female 22.8
Sample C Male 26.5
Sample D Male 17.7
Superior colliculi
nTPM: 18.1
Samples: 4

Max nTPM: 21.6
Min nTPM: 12.0
Sample A Female 19.8
Sample B Female 12.0
Sample C Male 19.1
Sample D Male 21.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

27.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 27.1
Samples: 4

Max nTPM: 27.9
Min nTPM: 26.4
Sample A Male 26.5
Sample B Male 27.4
Sample C Female 27.9
Sample D Female 26.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.1
71656816 Antisense, RP_050927_04_D05, Mouse strain C57BL/6J (56 days, male) 9.1

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