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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
42.7
nTPM
HPA:
42.7
nTPM
GTEx:
13.7
nTPM
FANTOM5:
110.5
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA015605
Cholangiocytes
Not detected
Hepatocytes
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
42.7
Female, age 60
Liver sample 21 nTPM: 44.7
Male, age 54
Liver sample 23 nTPM: 27.2
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 43.3
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 48.4
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 68.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 32.6
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 66.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 28.3
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 22
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 45.3
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
13.7
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 13.7
Samples: 226
Max nTPM: 132.9
Min nTPM: 0.0
Std nTPM: 13.5
Median nTPM: 10.3
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
132.9
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
60.0
GTEX-14XAO-0226-SM-68728
60-69 years, female
59.3
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
55.8
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
50.7
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
50.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
46.6
GTEX-S32W-1926-SM-4AD63
50-59 years, female
45.5
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
44.1
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
41.5
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
36.0
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
35.4
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
34.6
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
34.5
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
32.4
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
32.0
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
29.7
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
29.0
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
28.2
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
27.4
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
27.2
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
26.8
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
26.8
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
26.2
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
25.8
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
25.6
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
25.5
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
25.5
GTEX-17HHE-0126-SM-79398
50-59 years, male
25.2
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
25.1
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
25.1
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
24.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
24.5
GTEX-1B932-1426-SM-793AN
40-49 years, female
23.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
22.2
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
21.9
GTEX-QEL4-1226-SM-447A4
50-59 years, male
21.8
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
21.7
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
21.4
GTEX-14JG1-1626-SM-664NH
40-49 years, male
20.7
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
20.4
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
20.3
GTEX-R53T-0326-SM-48FEC
50-59 years, female
19.9
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
19.5
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
19.3
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
19.1
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
18.9
GTEX-14PHX-0526-SM-664NW
50-59 years, male
18.6
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
18.6
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
18.6
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
18.3
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
18.1
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
18.0
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
17.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
17.6
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
17.3
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
17.3
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
17.3
GTEX-REY6-1226-SM-48FDR
60-69 years, male
17.0
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
16.7
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
16.2
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
16.2
GTEX-O5YV-0726-SM-EV798
60-69 years, female
16.1
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
15.8
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
15.5
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
15.4
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
15.1
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
15.1
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
15.1
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
15.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
14.8
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
14.7
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
14.7
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
14.6
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
14.6
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
14.3
GTEX-17F96-1226-SM-79OK2
70-79 years, male
14.2
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
14.2
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
14.1
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
14.0
GTEX-1399T-0826-SM-5IFES
60-69 years, male
13.9
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
13.9
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
13.8
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
13.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
13.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
13.5
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
13.5
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
13.4
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
13.3
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
13.3
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
13.3
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
13.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
13.2
GTEX-QESD-2026-SM-447BI
20-29 years, male
12.6
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
12.4
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
12.3
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
12.2
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
12.0
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
11.9
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
11.8
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
11.8
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
11.8
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
11.4
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
11.3
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
11.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
11.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
10.8
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
10.7
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
10.5
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
10.4
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
10.4
GTEX-P78B-1326-SM-3P611
40-49 years, female
10.4
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
10.4
GTEX-12696-0826-SM-5EGGE
60-69 years, male
10.3
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
10.2
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
10.2
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
10.1
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
9.9
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
9.8
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
9.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
9.6
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
9.5
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
9.5
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
9.5
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
9.4
GTEX-14PJO-1726-SM-68719
60-69 years, male
9.3
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
9.2
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
9.2
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
8.9
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
8.8
GTEX-14E7W-1526-SM-6871X
70-79 years, male
8.8
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
8.7
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
8.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
8.6
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
8.5
GTEX-13113-1326-SM-5GCOI
60-69 years, female
8.4
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
8.4
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
8.4
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
8.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
8.0
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
7.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
7.9
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
7.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
7.8
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
7.8
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
7.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
7.8
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
7.6
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
7.6
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
7.5
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
7.4
GTEX-RN64-1826-SM-48FDV
50-59 years, male
7.4
GTEX-13112-1426-SM-5EGH8
50-59 years, male
7.3
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
7.3
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
7.3
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
7.0
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
6.9
GTEX-11ZUS-2526-SM-59872
30-39 years, male
6.7
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
6.7
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
6.6
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
6.5
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
6.3
GTEX-18A7A-1526-SM-72D69
50-59 years, female
6.2
GTEX-X261-1726-SM-4PQYT
50-59 years, male
6.2
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
6.1
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
6.0
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
6.0
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
6.0
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
5.8
GTEX-RU72-1426-SM-46MUF
50-59 years, female
5.7
GTEX-1B933-1226-SM-731DW
50-59 years, female
5.6
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
5.6
GTEX-18465-1626-SM-7LG6N
50-59 years, male
5.5
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
5.5
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
5.2
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
5.2
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
5.2
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
5.1
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
4.8
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
4.8
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
4.7
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
4.7
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
4.7
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
4.6
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
4.4
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
4.3
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
3.6
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
3.6
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
3.4
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
3.4
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
3.4
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
3.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
3.0
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
2.9
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
2.8
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
2.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
2.7
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
2.7
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
2.7
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
2.7
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
2.6
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
2.5
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
2.5
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
2.5
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
2.4
GTEX-144GL-1426-SM-79OMA
50-59 years, male
2.3
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
2.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
2.2
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
2.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
2.0
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
1.9
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
1.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
1.9
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
1.8
GTEX-11GSP-0626-SM-5986T
60-69 years, female
1.7
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
1.7
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
1.7
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
1.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
1.5
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
1.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
1.1
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
1.0
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
0.8
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
0.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
0.0
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
0.0
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
