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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:61.3 nTPM
HPA Brain:29.1 nTPM
GTEx:61.3 nTPM
FANTOM5:154.2 Scaled Tags Per Million
Pig:87.7 nTPM
Mouse:85.0 nTPM
Allen mouse:4.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

29.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 24.7
2411 Female, age 72, unknown 29.2
2019 Male, age 18, unknown 28.1
1870 Female, age 42, unknown 27.4
1827 Male, age 72, unknown 27.1
1833 Male, age 53, unknown 25.9
1830 Male, age 51, unknown 25.1
2828 Female, age 72, unknown 22.0
2219 Male, age 76, both hemispheres 21.8
2666 Male, age 74, left hemisphere 21.0
2586 Male, age 75, left hemisphere 19.6
Dorsal raphe nucleus
nTPM: 26.7
2298 Female, age 72, unknown 28.7
2750 Male, age 76, both hemispheres 27.1
1828 Male, age 53, unknown 26.2
2047 Male, age 72, unknown 26.1
2016 Female, age 72, unknown 25.2
Inferior colliculus
nTPM: 25.2
2097 Female, age 72, unknown 28.7
1890 Male, age 53, unknown 26.4
1848 Female, age 42, unknown 23.4
2849 Male, age 72, unknown 22.2
Median raphe nucleus
nTPM: 25.7
2220 Male, age 76, midline 25.7
Periaquaductal grey, anterior
nTPM: 24.3
1947 Male, age 18, unknown 26.4
2502 Female, age 75, unknown 24.8
1795 Male, age 51, unknown 21.6
Periaquaductal grey, dorsal
nTPM: 22.4
2850 Male, age 76, both hemispheres 23.1
1840 Male, age 53, unknown 22.6
2464 Female, age 72, unknown 22.0
1831 Male, age 72, unknown 21.8
Periaquaductal grey, lateral
nTPM: 24.5
2272 Male, age 74, both hemispheres 30.3
2053 Male, age 18, unknown 24.1
2140 Male, age 76, both hemispheres 19.0
Pretectal area
nTPM: 26.3
1944 Female, age 72, unknown 31.2
2007 Male, age 72, unknown 30.0
1817 Female, age 42, unknown 29.7
2667 Female, age 75, unknown 28.5
1816 Male, age 51, unknown 28.4
1815 Male, age 53, unknown 27.7
2273 Male, age 74, both hemispheres 27.4
2224 Female, age 72, unknown 26.3
2316 Male, age 76, right hemisphere 21.1
2825 Male, age 18, unknown 20.2
2407 Male, age 75, both hemispheres 19.2
Red nucleus
nTPM: 27.0
1821 Female, age 72, unknown 36.3
2725 Female, age 75, unknown 31.0
1865 Male, age 51, unknown 29.3
1904 Male, age 53, unknown 29.0
1954 Female, age 42, unknown 27.5
2823 Male, age 76, right hemisphere 27.3
2785 Male, age 18, unknown 26.3
2503 Female, age 72, unknown 25.5
2227 Male, age 72, unknown 25.2
2769 Male, age 72, unknown 24.6
2588 Male, age 74, left hemisphere 21.6
2584 Male, age 75, left hemisphere 20.8
Substantia nigra
nTPM: 29.1
2409 Female, age 72, unknown 41.3
1916 Female, age 42, unknown 34.9
2241 Male, age 72, unknown 32.8
1851 Male, age 51, unknown 31.1
1889 Female, age 72, unknown 29.5
1941 Male, age 53, unknown 29.0
2699 Male, age 18, unknown 27.4
2665 Male, age 74, both hemispheres 24.7
2590 Female, age 75, unknown 21.1
2583 Male, age 75, right hemisphere 18.8
Superior colliculus
nTPM: 25.5
2587 Male, age 74, left hemisphere 31.9
1895 Male, age 76, right hemisphere 29.3
2087 Female, age 72, unknown 27.1
2261 Male, age 18, unknown 27.1
1913 Female, age 42, unknown 26.7
2668 Female, age 75, unknown 26.1
1995 Male, age 72, unknown 23.3
1839 Male, age 51, unknown 22.6
1796 Male, age 53, unknown 22.5
2664 Male, age 75, both hemispheres 18.0
Ventral tegmental area
nTPM: 27.0
2410 Female, age 72, unknown 31.1
2223 Female, age 72, unknown 28.8
1915 Female, age 42, unknown 27.9
2218 Male, age 76, both hemispheres 26.2
1942 Male, age 51, unknown 25.0
2021 Male, age 53, unknown 23.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

61.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 61.3
Samples: 139

Max nTPM: 99.9
Min nTPM: 36.7
Std nTPM: 11.1
Median nTPM: 59.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 99.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 98.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 88.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 87.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 87.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 85.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 81.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 80.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 80.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 79.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 79.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 79.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 78.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 73.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 73.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 73.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 73.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 72.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 72.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 72.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 72.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 72.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 72.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 71.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 70.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 70.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 69.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 69.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 69.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 69.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 68.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 67.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 67.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 66.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 66.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 66.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 66.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 66.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 66.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 65.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 65.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 65.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 65.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 65.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 65.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 65.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 64.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 64.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 64.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 64.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 64.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 64.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 64.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 63.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 63.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 63.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 63.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 62.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 62.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 62.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 62.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 62.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 60.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 60.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 60.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 60.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 59.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 59.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 59.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 59.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 59.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 59.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 59.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 59.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 59.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 58.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 58.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 58.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 58.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 58.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 58.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 58.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 58.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 58.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 58.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 57.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 57.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 57.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 56.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 56.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 56.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 55.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 55.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 55.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 55.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 55.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 55.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 55.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 55.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 54.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 54.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 54.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 54.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 54.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 54.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 54.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 53.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 53.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 53.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 53.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 52.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 52.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 51.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 51.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 51.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 51.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 51.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 50.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 50.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 50.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 49.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 48.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 48.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 48.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 48.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 48.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 48.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 48.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 47.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 46.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 46.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 44.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 43.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 43.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 42.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 41.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 41.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 40.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 36.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

154.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 154.2
FF:10158-103A5 76 years, female 154.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

87.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 80.7
Samples: 4

Max nTPM: 106.5
Min nTPM: 59.8
Sample A Female 106.5
Sample B Female 85.8
Sample C Male 70.8
Sample D Male 59.8
Midbrain
nTPM: 86.4
Samples: 4

Max nTPM: 106.1
Min nTPM: 66.8
Sample A Female 106.1
Sample B Female 89.7
Sample C Male 83.0
Sample D Male 66.8
Periaqueductal gray
nTPM: 65.9
Samples: 3

Max nTPM: 72.3
Min nTPM: 58.8
Sample B Female 72.3
Sample C Male 66.5
Sample D Male 58.8
Superior colliculi
nTPM: 87.7
Samples: 4

Max nTPM: 93.7
Min nTPM: 75.4
Sample A Female 93.7
Sample B Female 93.1
Sample C Male 88.7
Sample D Male 75.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

85.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 85.0
Samples: 4

Max nTPM: 88.6
Min nTPM: 81.0
Sample A Male 87.4
Sample B Male 88.6
Sample C Female 81.0
Sample D Female 83.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.2
70527975 Antisense, RP_050623_01_E09, Mouse strain C57BL/6J (56 days, male) 4.2

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