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General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene namei
Official gene symbol, which is typically a short form of the gene name, according to HGNC.
Assigned HPA protein class(es) for the encoded protein(s).
Cancer-related genes Disease related genes Human disease related genes Potential drug targets Transporters
Predicted locationi
All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.
Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.
Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).
The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Chromosome
20
Cytoband
q13.32
Chromosome location (bp)
58839718 - 58911192
Number of transcriptsi
Number of protein-coding transcripts from the gene as defined by Ensembl.
Useful information about the protein provided by UniProt.
Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) 1. Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP 2,3. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors 4. Stimulates the Ras signaling pathway via RAPGEF2 5. [P63092] Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms (By similarity). [Q5JWF2] ...show less
Molecular function (UniProt)i
Keywords assigned by UniProt to proteins due to their particular molecular function.
Transducer [P63092] Transducer [Q5JWF2]
Ligand (UniProt)i
Keywords assigned by UniProt to proteins because they bind, are associated with, or whose activity is dependent of some molecule.
This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. [provided by RefSeq, Aug 2012]...show less
PROTEIN INFORMATIONi
The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.
The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.
The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
P63092 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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Transporters Accessory Factors Involved in Transport Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Disease related genes Potential drug targets Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
A0A0A0MR13 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A8I5F5B5 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
THUMBUP predicted membrane proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Disease related genes Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
A2A2R6 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
Q5JWE9 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
P63092 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Transporters Accessory Factors Involved in Transport Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Disease related genes Potential drug targets Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
THUMBUP predicted membrane proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Disease related genes Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Q5JWD1 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
P63092 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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A0A0S2Z3H8 [Target identity:100%; Query identity:100%] GNAS complex locus isoform 1
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Transporters Accessory Factors Involved in Transport Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Disease related genes Potential drug targets Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
P63092 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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A0A0S2Z3S5 [Target identity:100%; Query identity:100%] GNAS complex locus isoform 2
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Transporters Accessory Factors Involved in Transport Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Disease related genes Potential drug targets Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
THUMBUP predicted membrane proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Disease related genes Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Disease related genes Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Disease related genes Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
H0Y7Z6 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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THUMBUP predicted membrane proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Disease related genes Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
H0Y7E8 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A2A2S1 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
THUMBUP predicted membrane proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Disease related genes Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
A0A590UK28 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
B0AZR9 [Direct mapping] GNAS complex locus, isoform CRA_b; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; cDNA, FLJ79509, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha; cDNA, FLJ79523, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UJX3 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UK28 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
B0AZR9 [Direct mapping] GNAS complex locus, isoform CRA_b; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; cDNA, FLJ79509, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha; cDNA, FLJ79523, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UJS2 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
B0AZR9 [Direct mapping] GNAS complex locus, isoform CRA_b; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; cDNA, FLJ79509, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha; cDNA, FLJ79523, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UJQ9 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
B0AZR9 [Direct mapping] GNAS complex locus, isoform CRA_b; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; cDNA, FLJ79509, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha; cDNA, FLJ79523, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UJF0 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
B0AZR9 [Direct mapping] GNAS complex locus, isoform CRA_b; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; cDNA, FLJ79509, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha; cDNA, FLJ79523, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UK28 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UJQ9 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UJF0 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UK28 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UJF0 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UJ47 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UK28 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UK28 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
B0AZR9 [Direct mapping] GNAS complex locus, isoform CRA_b; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; cDNA, FLJ79509, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha; cDNA, FLJ79523, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UJ47 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UK28 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UJX3 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
B0AZR9 [Direct mapping] GNAS complex locus, isoform CRA_b; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; cDNA, FLJ79509, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha; cDNA, FLJ79523, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
B0AZR9 [Direct mapping] GNAS complex locus, isoform CRA_b; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; cDNA, FLJ79509, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha; cDNA, FLJ79523, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UJY2 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
B0AZR9 [Direct mapping] GNAS complex locus, isoform CRA_b; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; cDNA, FLJ79509, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha; cDNA, FLJ79523, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A590UJQ9 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
B0AZR9 [Direct mapping] GNAS complex locus, isoform CRA_b; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; cDNA, FLJ79509, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha; cDNA, FLJ79523, highly similar to Guanine nucleotide-binding protein G(s)subunit alpha
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A7I2V5R6 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
A0A804HIH4 [Direct mapping] Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Missense Mutations Human disease related genes Congenital malformations Congenital malformations of the musculoskeletal system Endocrine and metabolic diseases Hypothalamus and pituitary gland diseases Parathyroid diseases Adrenal gland diseases Musculoskeletal diseases Skeletal diseases Protein evidence (Ezkurdia et al 2014)
The Human Protein Atlas project is funded
