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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:61.0 nTPM
HPA Brain:64.3 nTPM
GTEx:61.0 nTPM
FANTOM5:55.3 Scaled Tags Per Million
Pig:46.6 nTPM
Mouse:37.0 nTPM
Allen mouse:0.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

64.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 57.8
2586 Male, age 75, left hemisphere 91.4
2828 Female, age 72, unknown 79.8
1833 Male, age 53, unknown 57.6
1870 Female, age 42, unknown 57.1
1830 Male, age 51, unknown 55.3
2666 Male, age 74, left hemisphere 53.4
1827 Male, age 72, unknown 51.3
2411 Female, age 72, unknown 49.3
2019 Male, age 18, unknown 46.7
2219 Male, age 76, both hemispheres 36.2
Dorsal raphe nucleus
nTPM: 60.9
2016 Female, age 72, unknown 69.8
1828 Male, age 53, unknown 66.5
2047 Male, age 72, unknown 62.9
2750 Male, age 76, both hemispheres 52.8
2298 Female, age 72, unknown 52.2
Inferior colliculus
nTPM: 56.4
1848 Female, age 42, unknown 58.4
2849 Male, age 72, unknown 58.2
1890 Male, age 53, unknown 57.0
2097 Female, age 72, unknown 52.1
Median raphe nucleus
nTPM: 37.8
2220 Male, age 76, midline 37.8
Periaquaductal grey, anterior
nTPM: 58.8
2502 Female, age 75, unknown 62.6
1947 Male, age 18, unknown 57.4
1795 Male, age 51, unknown 56.5
Periaquaductal grey, dorsal
nTPM: 59.7
2850 Male, age 76, both hemispheres 76.7
1840 Male, age 53, unknown 55.7
2464 Female, age 72, unknown 54.4
1831 Male, age 72, unknown 52.1
Periaquaductal grey, lateral
nTPM: 58.2
2140 Male, age 76, both hemispheres 79.3
2053 Male, age 18, unknown 56.4
2272 Male, age 74, both hemispheres 38.9
Pretectal area
nTPM: 53.6
2316 Male, age 76, right hemisphere 68.4
2825 Male, age 18, unknown 59.1
2667 Female, age 75, unknown 56.6
1815 Male, age 53, unknown 54.8
2407 Male, age 75, both hemispheres 54.6
1817 Female, age 42, unknown 53.9
2273 Male, age 74, both hemispheres 52.0
1944 Female, age 72, unknown 50.1
2007 Male, age 72, unknown 48.3
2224 Female, age 72, unknown 48.2
1816 Male, age 51, unknown 43.7
Red nucleus
nTPM: 64.3
2769 Male, age 72, unknown 74.4
2227 Male, age 72, unknown 72.0
1954 Female, age 42, unknown 70.5
1821 Female, age 72, unknown 69.7
2503 Female, age 72, unknown 69.2
1904 Male, age 53, unknown 67.9
1865 Male, age 51, unknown 63.9
2588 Male, age 74, left hemisphere 63.6
2725 Female, age 75, unknown 60.6
2823 Male, age 76, right hemisphere 59.3
2584 Male, age 75, left hemisphere 51.8
2785 Male, age 18, unknown 48.5
Substantia nigra
nTPM: 53.7
2699 Male, age 18, unknown 79.0
1916 Female, age 42, unknown 65.3
1851 Male, age 51, unknown 59.4
1889 Female, age 72, unknown 56.4
2583 Male, age 75, right hemisphere 54.2
2665 Male, age 74, both hemispheres 49.3
2409 Female, age 72, unknown 48.2
2590 Female, age 75, unknown 44.1
1941 Male, age 53, unknown 42.9
2241 Male, age 72, unknown 37.9
Superior colliculus
nTPM: 58.9
1995 Male, age 72, unknown 77.4
2664 Male, age 75, both hemispheres 68.6
2668 Female, age 75, unknown 64.3
1913 Female, age 42, unknown 62.5
1796 Male, age 53, unknown 59.2
1839 Male, age 51, unknown 57.9
2261 Male, age 18, unknown 55.6
2087 Female, age 72, unknown 54.6
2587 Male, age 74, left hemisphere 44.3
1895 Male, age 76, right hemisphere 44.2
Ventral tegmental area
nTPM: 53.1
1942 Male, age 51, unknown 60.1
1915 Female, age 42, unknown 55.2
2021 Male, age 53, unknown 53.7
2410 Female, age 72, unknown 53.4
2218 Male, age 76, both hemispheres 50.1
2223 Female, age 72, unknown 45.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

61.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 61.0
Samples: 139

Max nTPM: 183.1
Min nTPM: 10.5
Std nTPM: 32.2
Median nTPM: 51.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 183.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 178.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 172.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 158.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 148.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 148.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 148.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 141.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 119.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 119.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 106.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 106.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 99.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 95.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 93.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 93.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 91.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 90.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 88.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 88.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 87.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 85.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 83.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 82.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 82.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 80.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 78.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 78.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 77.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 76.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 76.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 76.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 74.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 72.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 72.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 72.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 72.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 71.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 70.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 69.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 69.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 67.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 67.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 66.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 66.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 65.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 64.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 63.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 63.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 62.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 61.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 60.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 60.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 60.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 59.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 58.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 58.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 58.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 57.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 57.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 56.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 55.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 55.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 55.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 54.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 53.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 53.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 52.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 52.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 51.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 51.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 51.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 51.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 49.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 49.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 49.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 49.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 48.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 47.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 47.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 47.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 47.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 47.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 47.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 46.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 46.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 45.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 44.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 44.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 44.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 44.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 44.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 44.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 43.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 42.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 42.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 42.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 42.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 41.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 41.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 40.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 40.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 40.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 40.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 40.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 39.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 39.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 38.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 38.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 37.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 37.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 37.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 37.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 37.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 37.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 37.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 35.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 35.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 35.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 35.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 35.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 35.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 34.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 33.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 32.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 32.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 31.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 30.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 29.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 28.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 27.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 27.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 27.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 25.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 23.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 23.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 20.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 19.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 10.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

55.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 55.3
FF:10158-103A5 76 years, female 55.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

46.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 44.3
Samples: 4

Max nTPM: 53.7
Min nTPM: 35.8
Sample A Female 44.1
Sample B Female 35.8
Sample C Male 43.4
Sample D Male 53.7
Midbrain
nTPM: 46.6
Samples: 4

Max nTPM: 89.4
Min nTPM: 28.0
Sample A Female 89.4
Sample B Female 35.4
Sample C Male 33.7
Sample D Male 28.0
Periaqueductal gray
nTPM: 36.2
Samples: 3

Max nTPM: 39.7
Min nTPM: 34.2
Sample B Female 34.7
Sample C Male 39.7
Sample D Male 34.2
Superior colliculi
nTPM: 32.1
Samples: 4

Max nTPM: 39.9
Min nTPM: 19.4
Sample A Female 34.4
Sample B Female 19.4
Sample C Male 34.8
Sample D Male 39.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

37.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 37.0
Samples: 4

Max nTPM: 40.9
Min nTPM: 32.7
Sample A Male 40.9
Sample B Male 32.7
Sample C Female 34.3
Sample D Female 40.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.3
67881784 Antisense, RP_040923_01_A02, Mouse strain C57BL/6J (56 days, male) 0.3

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