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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
High
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
191.7
nTPM
HPA:
191.7
nTPM
GTEx:
113.0
nTPM
FANTOM5:
148.3
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA009078
Cholangiocytes
High
Hepatocytes
Low
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
191.7
Female, age 60
Liver sample 21 nTPM: 183.4
Male, age 54
Liver sample 23 nTPM: 117.4
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 169.2
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 239
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 224.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 187.7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 169.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 192.9
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 214.6
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 219.1
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
113.0
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 113.0
Samples: 226
Max nTPM: 194.1
Min nTPM: 51.7
Std nTPM: 27.8
Median nTPM: 109.3
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
194.1
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
191.1
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
189.3
GTEX-RU72-1426-SM-46MUF
50-59 years, female
187.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
179.3
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
174.9
GTEX-14JG1-1626-SM-664NH
40-49 years, male
171.9
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
171.7
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
167.9
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
166.8
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
164.5
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
162.1
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
161.5
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
159.2
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
157.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
156.9
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
156.4
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
156.3
GTEX-R53T-0326-SM-48FEC
50-59 years, female
155.5
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
154.9
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
153.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
152.0
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
151.5
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
150.7
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
150.6
GTEX-S33H-1626-SM-4AD68
30-39 years, male
149.8
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
148.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
147.7
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
146.9
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
146.8
GTEX-1399T-0826-SM-5IFES
60-69 years, male
146.2
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
145.2
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
143.7
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
143.4
GTEX-17HHE-0126-SM-79398
50-59 years, male
142.9
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
142.6
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
142.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
141.8
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
140.0
GTEX-14E7W-1526-SM-6871X
70-79 years, male
139.9
GTEX-S32W-1926-SM-4AD63
50-59 years, female
139.6
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
138.9
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
138.7
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
137.9
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
137.0
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
136.9
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
136.5
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
136.4
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
136.3
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
136.2
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
135.8
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
134.7
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
133.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
132.7
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
132.5
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
131.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
131.2
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
130.9
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
128.3
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
128.3
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
127.8
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
127.6
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
127.2
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
126.7
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
126.5
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
125.7
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
125.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
125.2
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
125.1
GTEX-1B932-1426-SM-793AN
40-49 years, female
125.0
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
124.9
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
124.3
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
123.6
GTEX-QESD-2026-SM-447BI
20-29 years, male
123.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
121.8
GTEX-18A7A-1526-SM-72D69
50-59 years, female
121.8
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
121.6
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
121.4
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
121.2
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
120.4
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
120.4
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
120.0
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
119.6
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
118.5
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
118.1
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
118.0
GTEX-18A66-2026-SM-7189C
60-69 years, male
115.8
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
115.7
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
115.4
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
115.4
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
115.4
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
115.3
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
115.1
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
115.0
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
114.6
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
114.4
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
114.2
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
114.2
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
113.9
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
113.6
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
113.4
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
112.9
GTEX-P78B-1326-SM-3P611
40-49 years, female
112.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
112.4
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
112.0
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
111.9
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
111.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
111.2
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
111.0
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
109.8
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
109.7
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
109.5
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
109.5
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
109.2
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
108.9
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
108.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
108.3
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
108.3
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
108.3
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
108.2
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
108.0
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
107.9
GTEX-18465-1626-SM-7LG6N
50-59 years, male
107.9
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
107.8
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
107.5
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
107.4
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
107.2
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
107.0
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
106.2
GTEX-Q734-0326-SM-48U15
40-49 years, female
106.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
105.5
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
105.5
GTEX-12696-0826-SM-5EGGE
60-69 years, male
105.1
GTEX-RN64-1826-SM-48FDV
50-59 years, male
104.9
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
104.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
104.2
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
104.0
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
104.0
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
103.9
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
103.6
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
103.1
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
103.1
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
102.2
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
101.8
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
101.3
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
101.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
100.4
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
99.9
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
99.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
99.3
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
99.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
98.5
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
98.3
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
97.8
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
97.7
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
97.6
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
97.5
GTEX-13112-1426-SM-5EGH8
50-59 years, male
97.3
GTEX-17F96-1226-SM-79OK2
70-79 years, male
96.6
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
96.6
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
95.8
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
95.5
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
94.7
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
93.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
93.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
93.1
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
93.0
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
92.9
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
92.6
GTEX-14PHX-0526-SM-664NW
50-59 years, male
92.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
92.3
GTEX-REY6-1226-SM-48FDR
60-69 years, male
92.0
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
91.3
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
91.3
GTEX-1B933-1226-SM-731DW
50-59 years, female
91.2
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
90.9
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
90.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
90.0
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
89.8
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
89.0
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
88.3
GTEX-O5YV-0726-SM-EV798
60-69 years, female
88.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
87.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
87.6
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
87.5
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
87.2
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
87.0
GTEX-13113-1326-SM-5GCOI
60-69 years, female
85.9
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
85.8
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
85.7
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
84.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
84.5
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
84.3
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
83.7
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
83.6
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
83.5
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
82.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
82.3
GTEX-X261-1726-SM-4PQYT
50-59 years, male
81.8
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
81.3
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
81.2
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
81.1
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
80.0
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
79.8
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
79.6
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
79.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
78.6
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
78.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
77.1
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
76.8
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
74.7
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
74.5
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
73.7
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
72.1
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
69.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
69.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
69.1
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
68.8
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
68.7
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
68.4
GTEX-14PJO-1726-SM-68719
60-69 years, male
67.1
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
66.3
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
63.0
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
62.6
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
58.6
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
51.7
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
