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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:10.8 nTPM
HPA Brain:38.8 nTPM
GTEx:10.8 nTPM
FANTOM5:36.1 Scaled Tags Per Million
Pig:40.7 nTPM
Mouse:26.9 nTPM
Allen mouse:4.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

38.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 34.5
1827 Male, age 72, unknown 38.6
1870 Female, age 42, unknown 36.6
2219 Male, age 76, both hemispheres 36.6
1833 Male, age 53, unknown 36.5
2411 Female, age 72, unknown 35.3
1830 Male, age 51, unknown 33.4
2586 Male, age 75, left hemisphere 33.2
2666 Male, age 74, left hemisphere 32.7
2019 Male, age 18, unknown 31.3
2828 Female, age 72, unknown 30.9
Dorsal raphe nucleus
nTPM: 34.3
2047 Male, age 72, unknown 36.1
2298 Female, age 72, unknown 34.7
2750 Male, age 76, both hemispheres 34.1
2016 Female, age 72, unknown 33.7
1828 Male, age 53, unknown 33.1
Inferior colliculus
nTPM: 38.8
2849 Male, age 72, unknown 42.7
1848 Female, age 42, unknown 38.9
2097 Female, age 72, unknown 38.3
1890 Male, age 53, unknown 35.3
Median raphe nucleus
nTPM: 37.6
2220 Male, age 76, midline 37.6
Periaquaductal grey, anterior
nTPM: 34.8
1947 Male, age 18, unknown 38.9
2502 Female, age 75, unknown 33.3
1795 Male, age 51, unknown 32.1
Periaquaductal grey, dorsal
nTPM: 35.6
1840 Male, age 53, unknown 41.3
2850 Male, age 76, both hemispheres 34.2
2464 Female, age 72, unknown 33.7
1831 Male, age 72, unknown 33.3
Periaquaductal grey, lateral
nTPM: 32.4
2053 Male, age 18, unknown 33.8
2272 Male, age 74, both hemispheres 32.1
2140 Male, age 76, both hemispheres 31.2
Pretectal area
nTPM: 34.5
1816 Male, age 51, unknown 38.0
1944 Female, age 72, unknown 36.4
2224 Female, age 72, unknown 36.4
1817 Female, age 42, unknown 35.9
2825 Male, age 18, unknown 35.2
2407 Male, age 75, both hemispheres 34.9
1815 Male, age 53, unknown 34.1
2007 Male, age 72, unknown 34.1
2667 Female, age 75, unknown 33.8
2273 Male, age 74, both hemispheres 31.7
2316 Male, age 76, right hemisphere 29.5
Red nucleus
nTPM: 33.5
1821 Female, age 72, unknown 38.0
2725 Female, age 75, unknown 37.4
2588 Male, age 74, left hemisphere 36.7
2503 Female, age 72, unknown 36.2
2584 Male, age 75, left hemisphere 34.3
1954 Female, age 42, unknown 33.3
1865 Male, age 51, unknown 31.6
2769 Male, age 72, unknown 31.1
2227 Male, age 72, unknown 31.0
1904 Male, age 53, unknown 30.8
2785 Male, age 18, unknown 30.8
2823 Male, age 76, right hemisphere 30.2
Substantia nigra
nTPM: 35.9
1916 Female, age 42, unknown 40.9
2241 Male, age 72, unknown 40.4
1941 Male, age 53, unknown 36.3
2665 Male, age 74, both hemispheres 35.8
1851 Male, age 51, unknown 35.2
1889 Female, age 72, unknown 35.2
2699 Male, age 18, unknown 35.1
2409 Female, age 72, unknown 34.5
2590 Female, age 75, unknown 33.8
2583 Male, age 75, right hemisphere 31.9
Superior colliculus
nTPM: 33.0
1839 Male, age 51, unknown 37.0
1895 Male, age 76, right hemisphere 37.0
2587 Male, age 74, left hemisphere 34.5
1796 Male, age 53, unknown 33.8
2261 Male, age 18, unknown 33.3
2087 Female, age 72, unknown 33.0
2668 Female, age 75, unknown 33.0
2664 Male, age 75, both hemispheres 30.8
1913 Female, age 42, unknown 30.2
1995 Male, age 72, unknown 27.7
Ventral tegmental area
nTPM: 34.3
1915 Female, age 42, unknown 36.0
2218 Male, age 76, both hemispheres 35.4
2410 Female, age 72, unknown 35.0
2021 Male, age 53, unknown 33.3
2223 Female, age 72, unknown 33.1
1942 Male, age 51, unknown 33.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

10.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 10.8
Samples: 139

Max nTPM: 20.8
Min nTPM: 2.8
Std nTPM: 2.8
Median nTPM: 10.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 20.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 19.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 17.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 17.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 16.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 15.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 15.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 15.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 15.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 15.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 14.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 14.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 14.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 14.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 14.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 14.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 13.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 13.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 13.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 13.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 13.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 13.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 13.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 13.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 13.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 13.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 13.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 13.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 13.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 12.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 12.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 12.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 12.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 12.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 12.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 12.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 12.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 12.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 12.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 12.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 12.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 12.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 11.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 11.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 11.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 11.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 11.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 11.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 11.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 11.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 11.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 11.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 11.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 11.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 11.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 11.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 11.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 11.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 11.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 11.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 11.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 11.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 11.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 11.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 10.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 10.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 10.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 10.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 10.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 10.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 10.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 10.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 10.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 10.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 10.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 10.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 10.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 10.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 10.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 9.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 9.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 9.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 9.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 9.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 9.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 9.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 9.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 9.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 9.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 9.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 9.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 9.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 9.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 9.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 9.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 9.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 9.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 9.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 9.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 9.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 9.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 9.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 8.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 8.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 8.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 8.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 8.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 8.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 8.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 8.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 8.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 8.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 8.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 8.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 8.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 8.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 8.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 8.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 7.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 7.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 7.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 7.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 7.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 7.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 7.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 7.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 7.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 7.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 6.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 6.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 6.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 6.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 6.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 6.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 5.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 5.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 5.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 3.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

36.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 36.1
FF:10158-103A5 76 years, female 36.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

40.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 38.1
Samples: 4

Max nTPM: 43.8
Min nTPM: 31.7
Sample A Female 43.8
Sample B Female 36.3
Sample C Male 40.4
Sample D Male 31.7
Midbrain
nTPM: 40.7
Samples: 4

Max nTPM: 44.0
Min nTPM: 37.1
Sample A Female 43.1
Sample B Female 38.7
Sample C Male 37.1
Sample D Male 44.0
Periaqueductal gray
nTPM: 38.8
Samples: 3

Max nTPM: 44.4
Min nTPM: 34.5
Sample B Female 37.5
Sample C Male 44.4
Sample D Male 34.5
Superior colliculi
nTPM: 40.0
Samples: 4

Max nTPM: 45.8
Min nTPM: 35.9
Sample A Female 45.8
Sample B Female 35.9
Sample C Male 36.6
Sample D Male 41.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

26.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 26.9
Samples: 4

Max nTPM: 28.2
Min nTPM: 25.1
Sample A Male 25.1
Sample B Male 27.6
Sample C Female 28.2
Sample D Female 26.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.5
69838741 Antisense, RP_050321_03_D10, Mouse strain C57BL/6J (56 days, male) 4.5

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