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General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene namei
Official gene symbol, which is typically a short form of the gene name, according to HGNC.
Assigned HPA protein class(es) for the encoded protein(s).
Disease related genes Enzymes FDA approved drug targets Human disease related genes
Predicted locationi
All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.
Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.
Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).
The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Chromosome
X
Cytoband
p11.23
Chromosome location (bp)
48801377 - 48824982
Number of transcriptsi
Number of protein-coding transcripts from the gene as defined by Ensembl.
Useful information about the protein provided by UniProt.
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) 1. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events 2. Histone deacetylases act via the formation of large multiprotein complexes 3. In addition to histones, deacetylates other proteins, such as CTTN, tubulin and SQSTM1 4,5,6,7,8. Plays a central role in microtubule-dependent cell motility by mediating deacetylation of tubulin 9,10,11. Required for cilia disassembly; via deacetylation of alpha-tubulin 12,13. Promotes deacetylation of CTTN, leading to actin polymerization, promotion of autophagosome-lysosome fusion and completion of autophagy 14. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer 15. Promotes odontoblast differentiation following IPO7-mediated nuclear import and subsequent repression of RUNX2 expression (By similarity). In addition to its protein deacetylase activity, plays a key role in the degradation of misfolded proteins: when misfolded proteins are too abundant to be degraded by the chaperone refolding system and the ubiquitin-proteasome, mediates the transport of misfolded proteins to a cytoplasmic juxtanuclear structure called aggresome 16. Probably acts as an adapter that recognizes polyubiquitinated misfolded proteins and target them to the aggresome, facilitating their clearance by autophagy 17....show less
Molecular function (UniProt)i
Keywords assigned by UniProt to proteins due to their particular molecular function.
Keywords assigned by UniProt to proteins because they bind, are associated with, or whose activity is dependent of some molecule.
Metal-binding, Zinc
Gene summary (Entrez)i
Useful information about the gene from Entrez
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]...show less
PROTEIN INFORMATIONi
The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.
The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.
The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Enzymes ENZYME proteins Hydrolases THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes FDA approved drug targets Small molecule drugs Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000118[histone deacetylase complex] GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000209[protein polyubiquitination] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0001222[transcription corepressor binding] GO:0001932[regulation of protein phosphorylation] GO:0001975[response to amphetamine] GO:0003779[actin binding] GO:0004407[histone deacetylase activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005737[cytoplasm] GO:0005771[multivesicular body] GO:0005813[centrosome] GO:0005829[cytosol] GO:0005856[cytoskeleton] GO:0005874[microtubule] GO:0005875[microtubule associated complex] GO:0005901[caveola] GO:0005929[cilium] GO:0006325[chromatin organization] GO:0006476[protein deacetylation] GO:0006511[ubiquitin-dependent protein catabolic process] GO:0006515[protein quality control for misfolded or incompletely synthesized proteins] GO:0006886[intracellular protein transport] GO:0006914[autophagy] GO:0007026[negative regulation of microtubule depolymerization] GO:0008013[beta-catenin binding] GO:0008017[microtubule binding] GO:0008270[zinc ion binding] GO:0010506[regulation of autophagy] GO:0010634[positive regulation of epithelial cell migration] GO:0010727[negative regulation of hydrogen peroxide metabolic process] GO:0010821[regulation of mitochondrion organization] GO:0010977[negative regulation of neuron projection development] GO:0015630[microtubule cytoskeleton] GO:0016234[inclusion body] GO:0016235[aggresome] GO:0016241[regulation of macroautophagy] GO:0016575[histone deacetylation] GO:0016787[hydrolase activity] GO:0019213[deacetylase activity] GO:0019896[axonal transport of mitochondrion] GO:0019899[enzyme binding] GO:0030182[neuron differentiation] GO:0030424[axon] GO:0030425[dendrite] GO:0031252[cell leading edge] GO:0031333[negative regulation of protein-containing complex assembly] GO:0031593[polyubiquitin modification-dependent protein binding] GO:0031625[ubiquitin protein ligase binding] GO:0031647[regulation of protein stability] GO:0031648[protein destabilization] GO:0032418[lysosome localization] GO:0032984[protein-containing complex disassembly] GO:0032991[protein-containing complex] GO:0033138[positive regulation of peptidyl-serine phosphorylation] GO:0033558[protein lysine deacetylase activity] GO:0034599[cellular response to oxidative stress] GO:0034983[peptidyl-lysine deacetylation] GO:0035902[response to immobilization stress] GO:0035967[cellular response to topologically incorrect protein] GO:0036064[ciliary basal body] GO:0040029[epigenetic regulation of gene expression] GO:0042826[histone deacetylase binding] GO:0042903[tubulin deacetylase activity] GO:0042995[cell projection] GO:0043005[neuron projection] GO:0043014[alpha-tubulin binding] GO:0043025[neuronal cell body] GO:0043130[ubiquitin binding] GO:0043162[ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway] GO:0043204[perikaryon] GO:0043242[negative regulation of protein-containing complex disassembly] GO:0045598[regulation of fat cell differentiation] GO:0045861[negative regulation of proteolysis] GO:0045892[negative regulation of DNA-templated transcription] GO:0046872[metal ion binding] GO:0048156[tau protein binding] GO:0048471[perinuclear region of cytoplasm] GO:0048487[beta-tubulin binding] GO:0048668[collateral sprouting] GO:0048843[negative regulation of axon extension involved in axon guidance] GO:0050775[positive regulation of dendrite morphogenesis] GO:0051354[negative regulation of oxidoreductase activity] GO:0051412[response to corticosterone] GO:0051646[mitochondrion localization] GO:0051787[misfolded protein binding] GO:0051788[response to misfolded protein] GO:0051879[Hsp90 protein binding] GO:0051968[positive regulation of synaptic transmission, glutamatergic] GO:0060271[cilium assembly] GO:0060632[regulation of microtubule-based movement] GO:0060765[regulation of androgen receptor signaling pathway] GO:0060997[dendritic spine morphogenesis] GO:0061523[cilium disassembly] GO:0061734[parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization] GO:0070201[regulation of establishment of protein localization] GO:0070301[cellular response to hydrogen peroxide] GO:0070507[regulation of microtubule cytoskeleton organization] GO:0070840[dynein complex binding] GO:0070842[aggresome assembly] GO:0070845[polyubiquitinated misfolded protein transport] GO:0070846[Hsp90 deacetylation] GO:0070848[response to growth factor] GO:0071218[cellular response to misfolded protein] GO:0071374[cellular response to parathyroid hormone stimulus] GO:0071548[response to dexamethasone] GO:0090042[tubulin deacetylation] GO:0090044[positive regulation of tubulin deacetylation] GO:0098779[positive regulation of mitophagy in response to mitochondrial depolarization] GO:1901300[positive regulation of hydrogen peroxide-mediated programmed cell death] GO:1901984[negative regulation of protein acetylation] GO:1903146[regulation of autophagy of mitochondrion] GO:1903223[positive regulation of oxidative stress-induced neuron death] GO:1904056[positive regulation of cholangiocyte proliferation] GO:1904115[axon cytoplasm] GO:2000273[positive regulation of signaling receptor activity]
THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Enzymes ENZYME proteins Hydrolases THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes FDA approved drug targets Small molecule drugs Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000118[histone deacetylase complex] GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0001222[transcription corepressor binding] GO:0003779[actin binding] GO:0004407[histone deacetylase activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005737[cytoplasm] GO:0005771[multivesicular body] GO:0005829[cytosol] GO:0005856[cytoskeleton] GO:0005874[microtubule] GO:0005875[microtubule associated complex] GO:0005901[caveola] GO:0005929[cilium] GO:0006325[chromatin organization] GO:0006476[protein deacetylation] GO:0006515[protein quality control for misfolded or incompletely synthesized proteins] GO:0006886[intracellular protein transport] GO:0006914[autophagy] GO:0008013[beta-catenin binding] GO:0008017[microtubule binding] GO:0008270[zinc ion binding] GO:0010506[regulation of autophagy] GO:0010634[positive regulation of epithelial cell migration] GO:0010727[negative regulation of hydrogen peroxide metabolic process] GO:0016234[inclusion body] GO:0016235[aggresome] GO:0016241[regulation of macroautophagy] GO:0016575[histone deacetylation] GO:0016787[hydrolase activity] GO:0019896[axonal transport of mitochondrion] GO:0019899[enzyme binding] GO:0030424[axon] GO:0030425[dendrite] GO:0031252[cell leading edge] GO:0031333[negative regulation of protein-containing complex assembly] GO:0031593[polyubiquitin modification-dependent protein binding] GO:0031625[ubiquitin protein ligase binding] GO:0031647[regulation of protein stability] GO:0032418[lysosome localization] GO:0033138[positive regulation of peptidyl-serine phosphorylation] GO:0033558[protein lysine deacetylase activity] GO:0034983[peptidyl-lysine deacetylation] GO:0035967[cellular response to topologically incorrect protein] GO:0036064[ciliary basal body] GO:0040029[epigenetic regulation of gene expression] GO:0042826[histone deacetylase binding] GO:0042903[tubulin deacetylase activity] GO:0042995[cell projection] GO:0043014[alpha-tubulin binding] GO:0043204[perikaryon] GO:0043242[negative regulation of protein-containing complex disassembly] GO:0045861[negative regulation of proteolysis] GO:0045892[negative regulation of DNA-templated transcription] GO:0046872[metal ion binding] GO:0048156[tau protein binding] GO:0048471[perinuclear region of cytoplasm] GO:0051354[negative regulation of oxidoreductase activity] GO:0051787[misfolded protein binding] GO:0051788[response to misfolded protein] GO:0051879[Hsp90 protein binding] GO:0060271[cilium assembly] GO:0060632[regulation of microtubule-based movement] GO:0060765[regulation of androgen receptor signaling pathway] GO:0061523[cilium disassembly] GO:0061734[parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization] GO:0070301[cellular response to hydrogen peroxide] GO:0070840[dynein complex binding] GO:0070842[aggresome assembly] GO:0070845[polyubiquitinated misfolded protein transport] GO:0070848[response to growth factor] GO:0090042[tubulin deacetylation] GO:1901300[positive regulation of hydrogen peroxide-mediated programmed cell death] GO:1903146[regulation of autophagy of mitochondrion] GO:1904115[axon cytoplasm] GO:2000273[positive regulation of signaling receptor activity]
THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Enzymes ENZYME proteins Hydrolases THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes FDA approved drug targets Small molecule drugs Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000118[histone deacetylase complex] GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0001222[transcription corepressor binding] GO:0003779[actin binding] GO:0004407[histone deacetylase activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005737[cytoplasm] GO:0005771[multivesicular body] GO:0005829[cytosol] GO:0005856[cytoskeleton] GO:0005874[microtubule] GO:0005875[microtubule associated complex] GO:0005901[caveola] GO:0005929[cilium] GO:0006325[chromatin organization] GO:0006476[protein deacetylation] GO:0006515[protein quality control for misfolded or incompletely synthesized proteins] GO:0006886[intracellular protein transport] GO:0006914[autophagy] GO:0008013[beta-catenin binding] GO:0008017[microtubule binding] GO:0008270[zinc ion binding] GO:0010506[regulation of autophagy] GO:0010634[positive regulation of epithelial cell migration] GO:0010727[negative regulation of hydrogen peroxide metabolic process] GO:0016234[inclusion body] GO:0016235[aggresome] GO:0016241[regulation of macroautophagy] GO:0016575[histone deacetylation] GO:0016787[hydrolase activity] GO:0019896[axonal transport of mitochondrion] GO:0019899[enzyme binding] GO:0030424[axon] GO:0030425[dendrite] GO:0031252[cell leading edge] GO:0031333[negative regulation of protein-containing complex assembly] GO:0031593[polyubiquitin modification-dependent protein binding] GO:0031625[ubiquitin protein ligase binding] GO:0031647[regulation of protein stability] GO:0032418[lysosome localization] GO:0033138[positive regulation of peptidyl-serine phosphorylation] GO:0033558[protein lysine deacetylase activity] GO:0034983[peptidyl-lysine deacetylation] GO:0035967[cellular response to topologically incorrect protein] GO:0036064[ciliary basal body] GO:0040029[epigenetic regulation of gene expression] GO:0042826[histone deacetylase binding] GO:0042903[tubulin deacetylase activity] GO:0042995[cell projection] GO:0043014[alpha-tubulin binding] GO:0043204[perikaryon] GO:0043242[negative regulation of protein-containing complex disassembly] GO:0045861[negative regulation of proteolysis] GO:0045892[negative regulation of DNA-templated transcription] GO:0046872[metal ion binding] GO:0048156[tau protein binding] GO:0048471[perinuclear region of cytoplasm] GO:0051354[negative regulation of oxidoreductase activity] GO:0051787[misfolded protein binding] GO:0051788[response to misfolded protein] GO:0051879[Hsp90 protein binding] GO:0060271[cilium assembly] GO:0060632[regulation of microtubule-based movement] GO:0060765[regulation of androgen receptor signaling pathway] GO:0061523[cilium disassembly] GO:0061734[parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization] GO:0070301[cellular response to hydrogen peroxide] GO:0070840[dynein complex binding] GO:0070842[aggresome assembly] GO:0070845[polyubiquitinated misfolded protein transport] GO:0070848[response to growth factor] GO:0090042[tubulin deacetylation] GO:1901300[positive regulation of hydrogen peroxide-mediated programmed cell death] GO:1903146[regulation of autophagy of mitochondrion] GO:1904115[axon cytoplasm] GO:2000273[positive regulation of signaling receptor activity]
SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Enzymes ENZYME proteins Hydrolases THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes FDA approved drug targets Small molecule drugs Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000118[histone deacetylase complex] GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0001222[transcription corepressor binding] GO:0003779[actin binding] GO:0004407[histone deacetylase activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005737[cytoplasm] GO:0005771[multivesicular body] GO:0005829[cytosol] GO:0005856[cytoskeleton] GO:0005874[microtubule] GO:0005875[microtubule associated complex] GO:0005901[caveola] GO:0005929[cilium] GO:0006325[chromatin organization] GO:0006476[protein deacetylation] GO:0006515[protein quality control for misfolded or incompletely synthesized proteins] GO:0006886[intracellular protein transport] GO:0006914[autophagy] GO:0008013[beta-catenin binding] GO:0008017[microtubule binding] GO:0008270[zinc ion binding] GO:0010506[regulation of autophagy] GO:0010634[positive regulation of epithelial cell migration] GO:0010727[negative regulation of hydrogen peroxide metabolic process] GO:0016234[inclusion body] GO:0016235[aggresome] GO:0016241[regulation of macroautophagy] GO:0016575[histone deacetylation] GO:0016787[hydrolase activity] GO:0019896[axonal transport of mitochondrion] GO:0019899[enzyme binding] GO:0030424[axon] GO:0030425[dendrite] GO:0031252[cell leading edge] GO:0031333[negative regulation of protein-containing complex assembly] GO:0031593[polyubiquitin modification-dependent protein binding] GO:0031625[ubiquitin protein ligase binding] GO:0031647[regulation of protein stability] GO:0032418[lysosome localization] GO:0033138[positive regulation of peptidyl-serine phosphorylation] GO:0033558[protein lysine deacetylase activity] GO:0034983[peptidyl-lysine deacetylation] GO:0035967[cellular response to topologically incorrect protein] GO:0036064[ciliary basal body] GO:0040029[epigenetic regulation of gene expression] GO:0042826[histone deacetylase binding] GO:0042903[tubulin deacetylase activity] GO:0042995[cell projection] GO:0043014[alpha-tubulin binding] GO:0043204[perikaryon] GO:0043242[negative regulation of protein-containing complex disassembly] GO:0045861[negative regulation of proteolysis] GO:0045892[negative regulation of DNA-templated transcription] GO:0046872[metal ion binding] GO:0048156[tau protein binding] GO:0048471[perinuclear region of cytoplasm] GO:0051354[negative regulation of oxidoreductase activity] GO:0051787[misfolded protein binding] GO:0051788[response to misfolded protein] GO:0051879[Hsp90 protein binding] GO:0060271[cilium assembly] GO:0060632[regulation of microtubule-based movement] GO:0060765[regulation of androgen receptor signaling pathway] GO:0061523[cilium disassembly] GO:0061734[parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization] GO:0070301[cellular response to hydrogen peroxide] GO:0070840[dynein complex binding] GO:0070842[aggresome assembly] GO:0070845[polyubiquitinated misfolded protein transport] GO:0070848[response to growth factor] GO:0090042[tubulin deacetylation] GO:1901300[positive regulation of hydrogen peroxide-mediated programmed cell death] GO:1903146[regulation of autophagy of mitochondrion] GO:1904115[axon cytoplasm] GO:2000273[positive regulation of signaling receptor activity]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
THUMBUP predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
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