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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:48.2 nTPM
HPA Brain:351.7 nTPM
GTEx:48.2 nTPM
FANTOM5:203.0 Scaled Tags Per Million
Pig:60.7 nTPM
Mouse:66.1 nTPM
Allen mouse:1.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

351.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 178.9
2828 Female, age 72, unknown 265.6
2586 Male, age 75, left hemisphere 246.3
2666 Male, age 74, left hemisphere 206.3
1827 Male, age 72, unknown 191.7
1870 Female, age 42, unknown 173.8
1833 Male, age 53, unknown 155.2
1830 Male, age 51, unknown 153.1
2219 Male, age 76, both hemispheres 145.2
2019 Male, age 18, unknown 134.7
2411 Female, age 72, unknown 117.3
Dorsal raphe nucleus
nTPM: 228.5
2016 Female, age 72, unknown 342.7
1828 Male, age 53, unknown 245.8
2047 Male, age 72, unknown 225.0
2298 Female, age 72, unknown 194.4
2750 Male, age 76, both hemispheres 134.5
Inferior colliculus
nTPM: 184.0
2849 Male, age 72, unknown 207.6
1890 Male, age 53, unknown 197.7
1848 Female, age 42, unknown 193.4
2097 Female, age 72, unknown 137.1
Median raphe nucleus
nTPM: 166.9
2220 Male, age 76, midline 166.9
Periaquaductal grey, anterior
nTPM: 226.1
1795 Male, age 51, unknown 293.7
1947 Male, age 18, unknown 201.0
2502 Female, age 75, unknown 183.5
Periaquaductal grey, dorsal
nTPM: 280.4
2850 Male, age 76, both hemispheres 356.3
1831 Male, age 72, unknown 332.3
1840 Male, age 53, unknown 249.5
2464 Female, age 72, unknown 183.5
Periaquaductal grey, lateral
nTPM: 351.7
2053 Male, age 18, unknown 356.4
2140 Male, age 76, both hemispheres 356.3
2272 Male, age 74, both hemispheres 342.4
Pretectal area
nTPM: 240.9
2273 Male, age 74, both hemispheres 444.7
2407 Male, age 75, both hemispheres 337.7
2825 Male, age 18, unknown 249.7
2224 Female, age 72, unknown 242.5
2316 Male, age 76, right hemisphere 234.7
2667 Female, age 75, unknown 227.5
1944 Female, age 72, unknown 213.8
1815 Male, age 53, unknown 204.3
1816 Male, age 51, unknown 202.2
1817 Female, age 42, unknown 168.1
2007 Male, age 72, unknown 124.7
Red nucleus
nTPM: 150.2
2725 Female, age 75, unknown 214.5
2823 Male, age 76, right hemisphere 173.5
1865 Male, age 51, unknown 157.0
2584 Male, age 75, left hemisphere 151.2
1954 Female, age 42, unknown 146.0
2227 Male, age 72, unknown 145.3
2503 Female, age 72, unknown 139.4
1904 Male, age 53, unknown 138.4
2769 Male, age 72, unknown 137.4
1821 Female, age 72, unknown 137.0
2588 Male, age 74, left hemisphere 131.8
2785 Male, age 18, unknown 130.9
Substantia nigra
nTPM: 198.5
2699 Male, age 18, unknown 304.0
2590 Female, age 75, unknown 227.3
2583 Male, age 75, right hemisphere 219.5
1851 Male, age 51, unknown 194.4
1941 Male, age 53, unknown 183.0
2665 Male, age 74, both hemispheres 182.1
1916 Female, age 42, unknown 181.2
2409 Female, age 72, unknown 173.0
2241 Male, age 72, unknown 165.6
1889 Female, age 72, unknown 155.4
Superior colliculus
nTPM: 243.4
1995 Male, age 72, unknown 353.3
2664 Male, age 75, both hemispheres 316.5
1913 Female, age 42, unknown 308.4
2587 Male, age 74, left hemisphere 250.4
2087 Female, age 72, unknown 236.6
1796 Male, age 53, unknown 227.7
2261 Male, age 18, unknown 219.7
1839 Male, age 51, unknown 201.1
2668 Female, age 75, unknown 170.0
1895 Male, age 76, right hemisphere 150.4
Ventral tegmental area
nTPM: 211.3
2021 Male, age 53, unknown 273.1
1915 Female, age 42, unknown 224.0
1942 Male, age 51, unknown 223.2
2223 Female, age 72, unknown 208.8
2218 Male, age 76, both hemispheres 192.9
2410 Female, age 72, unknown 145.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

48.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 48.2
Samples: 139

Max nTPM: 103.1
Min nTPM: 12.4
Std nTPM: 21.5
Median nTPM: 46.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 103.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 100.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 100.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 98.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 97.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 95.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 90.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 88.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 87.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 87.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 85.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 81.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 79.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 79.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 78.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 77.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 77.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 77.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 72.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 71.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 70.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 70.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 69.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 69.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 69.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 69.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 68.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 68.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 67.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 67.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 66.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 66.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 65.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 64.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 63.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 63.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 60.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 60.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 59.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 59.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 58.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 57.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 56.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 54.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 54.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 54.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 53.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 52.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 52.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 52.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 52.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 52.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 52.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 51.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 50.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 50.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 50.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 49.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 49.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 49.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 49.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 49.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 48.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 48.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 48.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 47.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 46.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 46.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 46.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 46.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 46.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 46.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 45.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 45.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 43.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 43.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 42.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 41.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 40.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 40.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 39.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 39.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 39.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 38.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 38.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 38.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 37.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 37.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 36.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 36.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 35.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 35.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 34.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 34.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 34.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 34.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 32.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 32.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 32.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 32.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 32.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 31.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 31.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 30.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 30.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 30.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 29.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 29.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 29.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 28.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 28.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 27.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 27.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 27.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 27.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 26.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 26.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 26.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 24.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 24.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 24.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 23.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 23.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 23.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 23.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 23.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 22.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 21.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 21.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 21.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 19.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 19.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 18.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 18.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 18.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 16.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 16.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 16.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 12.4
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

203.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 203.0
FF:10158-103A5 76 years, female 203.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

60.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 55.0
Samples: 4

Max nTPM: 71.6
Min nTPM: 46.4
Sample A Female 46.4
Sample B Female 71.6
Sample C Male 48.8
Sample D Male 53.3
Midbrain
nTPM: 60.7
Samples: 4

Max nTPM: 116.7
Min nTPM: 28.8
Sample A Female 116.7
Sample B Female 28.8
Sample C Male 62.0
Sample D Male 35.1
Periaqueductal gray
nTPM: 50.6
Samples: 3

Max nTPM: 58.0
Min nTPM: 41.0
Sample B Female 41.0
Sample C Male 58.0
Sample D Male 52.7
Superior colliculi
nTPM: 57.2
Samples: 4

Max nTPM: 81.2
Min nTPM: 45.0
Sample A Female 45.0
Sample B Female 81.2
Sample C Male 51.7
Sample D Male 50.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

66.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 66.1
Samples: 4

Max nTPM: 77.2
Min nTPM: 57.1
Sample A Male 57.1
Sample B Male 60.6
Sample C Female 77.2
Sample D Female 69.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.1
69169391 Antisense, RP_050321_03_E01, Mouse strain C57BL/6J (56 days, male) 2.6
74425572 Antisense, RP_051214_02_H12, Mouse strain C57BL/6J (56 days, male) 0.4
71213156 Antisense, RP_050816_03_H12, Mouse strain C57BL/6J (56 days, male) 0.3

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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