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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:54.6 nTPM
HPA Brain:91.3 nTPM
GTEx:54.6 nTPM
FANTOM5:132.9 Scaled Tags Per Million
Pig:96.7 nTPM
Mouse:74.8 nTPM
Allen mouse:6.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

91.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 86.2
2586 Male, age 75, left hemisphere 95.2
2219 Male, age 76, both hemispheres 88.9
2828 Female, age 72, unknown 86.8
1833 Male, age 53, unknown 86.2
2666 Male, age 74, left hemisphere 85.5
2019 Male, age 18, unknown 85.4
1830 Male, age 51, unknown 84.1
1827 Male, age 72, unknown 83.7
2411 Female, age 72, unknown 83.1
1870 Female, age 42, unknown 82.7
Dorsal raphe nucleus
nTPM: 80.2
2750 Male, age 76, both hemispheres 87.6
1828 Male, age 53, unknown 82.5
2047 Male, age 72, unknown 77.7
2298 Female, age 72, unknown 77.5
2016 Female, age 72, unknown 75.9
Inferior colliculus
nTPM: 81.4
2849 Male, age 72, unknown 84.0
1890 Male, age 53, unknown 82.6
1848 Female, age 42, unknown 80.9
2097 Female, age 72, unknown 78.2
Median raphe nucleus
nTPM: 89.7
2220 Male, age 76, midline 89.7
Periaquaductal grey, anterior
nTPM: 88.4
2502 Female, age 75, unknown 93.6
1947 Male, age 18, unknown 90.2
1795 Male, age 51, unknown 81.5
Periaquaductal grey, dorsal
nTPM: 80.1
2850 Male, age 76, both hemispheres 83.1
1840 Male, age 53, unknown 81.5
1831 Male, age 72, unknown 79.1
2464 Female, age 72, unknown 76.5
Periaquaductal grey, lateral
nTPM: 78.0
2140 Male, age 76, both hemispheres 82.2
2272 Male, age 74, both hemispheres 77.3
2053 Male, age 18, unknown 74.5
Pretectal area
nTPM: 86.0
2007 Male, age 72, unknown 98.6
1815 Male, age 53, unknown 96.7
1817 Female, age 42, unknown 96.3
1816 Male, age 51, unknown 95.8
1944 Female, age 72, unknown 91.6
2407 Male, age 75, both hemispheres 84.5
2224 Female, age 72, unknown 78.1
2825 Male, age 18, unknown 78.1
2667 Female, age 75, unknown 77.0
2273 Male, age 74, both hemispheres 75.8
2316 Male, age 76, right hemisphere 73.1
Red nucleus
nTPM: 91.3
2503 Female, age 72, unknown 105.0
2588 Male, age 74, left hemisphere 96.2
2584 Male, age 75, left hemisphere 95.8
1821 Female, age 72, unknown 95.5
2725 Female, age 75, unknown 93.2
2785 Male, age 18, unknown 92.9
2769 Male, age 72, unknown 92.0
1865 Male, age 51, unknown 88.7
2227 Male, age 72, unknown 88.0
1904 Male, age 53, unknown 87.4
1954 Female, age 42, unknown 80.8
2823 Male, age 76, right hemisphere 80.2
Substantia nigra
nTPM: 86.3
1916 Female, age 42, unknown 92.7
2665 Male, age 74, both hemispheres 89.6
1889 Female, age 72, unknown 89.5
1851 Male, age 51, unknown 89.0
2409 Female, age 72, unknown 87.5
2699 Male, age 18, unknown 87.5
2241 Male, age 72, unknown 87.2
1941 Male, age 53, unknown 81.7
2590 Female, age 75, unknown 79.7
2583 Male, age 75, right hemisphere 79.1
Superior colliculus
nTPM: 84.8
2668 Female, age 75, unknown 93.7
2261 Male, age 18, unknown 92.3
1913 Female, age 42, unknown 87.8
1839 Male, age 51, unknown 85.7
2587 Male, age 74, left hemisphere 85.5
2664 Male, age 75, both hemispheres 84.2
1796 Male, age 53, unknown 83.7
2087 Female, age 72, unknown 81.3
1995 Male, age 72, unknown 77.2
1895 Male, age 76, right hemisphere 76.5
Ventral tegmental area
nTPM: 85.2
2410 Female, age 72, unknown 92.5
2218 Male, age 76, both hemispheres 89.1
2223 Female, age 72, unknown 87.1
1942 Male, age 51, unknown 82.7
1915 Female, age 42, unknown 81.2
2021 Male, age 53, unknown 78.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

54.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 54.6
Samples: 139

Max nTPM: 92.3
Min nTPM: 35.2
Std nTPM: 10.4
Median nTPM: 54.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 92.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 84.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 82.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 82.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 75.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 74.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 74.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 73.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 72.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 72.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 71.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 71.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 70.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 67.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 67.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 67.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 66.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 65.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 65.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 64.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 64.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 64.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 63.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 63.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 63.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 63.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 62.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 61.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 61.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 61.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 61.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 61.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 61.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 60.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 60.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 60.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 59.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 58.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 58.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 58.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 58.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 57.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 57.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 57.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 57.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 57.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 57.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 57.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 56.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 56.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 56.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 56.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 56.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 56.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 56.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 56.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 55.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 55.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 55.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 55.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 55.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 55.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 54.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 54.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 54.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 54.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 54.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 54.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 54.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 54.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 54.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 54.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 54.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 53.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 53.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 53.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 52.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 52.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 52.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 51.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 51.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 51.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 51.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 51.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 50.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 50.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 50.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 50.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 50.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 49.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 49.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 49.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 49.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 49.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 49.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 49.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 49.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 49.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 48.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 48.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 48.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 47.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 47.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 47.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 47.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 46.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 46.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 46.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 46.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 46.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 45.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 45.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 45.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 45.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 45.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 44.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 44.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 44.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 43.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 43.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 43.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 43.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 42.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 42.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 42.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 41.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 41.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 41.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 40.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 40.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 40.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 39.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 39.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 39.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 38.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 37.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 36.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 36.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 35.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

132.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 132.9
FF:10158-103A5 76 years, female 132.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

96.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 84.4
Samples: 4

Max nTPM: 92.1
Min nTPM: 77.0
Sample A Female 88.9
Sample B Female 77.0
Sample C Male 92.1
Sample D Male 79.4
Midbrain
nTPM: 96.7
Samples: 4

Max nTPM: 109.2
Min nTPM: 87.9
Sample A Female 96.7
Sample B Female 87.9
Sample C Male 109.2
Sample D Male 93.0
Periaqueductal gray
nTPM: 82.0
Samples: 3

Max nTPM: 86.1
Min nTPM: 79.3
Sample B Female 80.6
Sample C Male 86.1
Sample D Male 79.3
Superior colliculi
nTPM: 93.2
Samples: 4

Max nTPM: 100.2
Min nTPM: 74.9
Sample A Female 97.4
Sample B Female 74.9
Sample C Male 100.2
Sample D Male 100.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

74.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 74.8
Samples: 4

Max nTPM: 77.4
Min nTPM: 70.9
Sample A Male 70.9
Sample B Male 76.5
Sample C Female 77.4
Sample D Female 74.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.4
71281111 Antisense, RP_050818_02_B04, Mouse strain C57BL/6J (56 days, male) 6.4

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