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TPSD1
HPA
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  • TPSD1
CELL LINE
ADRENOCORTICAL CANCER BILE DUCT CANCER BLADDER CANCER BONE CANCER BRAIN CANCER BREAST CANCER CERVICAL CANCER COLORECTAL CANCER ESOPHAGEAL CANCER GALLBLADDER CANCER
GASTRIC CANCER HEAD AND NECK CANCER KIDNEY CANCER LEUKEMIA LIVER CANCER LUNG CANCER LYMPHOMA MYELOMA NEUROBLASTOMA NON-CANCEROUS
OVARIAN CANCER PANCREATIC CANCER PROSTATE CANCER RHABDOID SARCOMA SKIN CANCER TESTIS CANCER THYROID CANCER UNCATEGORIZED UTERINE CANCER
Human cell lines
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

TPSD1
Gene descriptioni

Full gene name according to HGNC.

Tryptase delta 1
Protein classi

Assigned HPA protein class(es) for the encoded protein(s).

Enzymes
Metabolic proteins
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

2
HUMAN PROTEIN ATLAS INFORMATIONi

Summary of RNA expression based on cell line data from the DepMap portal and cell line data generated within the Human Protein Atlas project.

Cell line expression clusteri

The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity.

HMC-1 - Innate immune response (mainly)
Cell line specificityi

RNA specificity category based on RNA sequencing data from cancer cell lines in the Human Protein Atlas grouped according to type of cancer. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.

Cancer enriched (Leukemia)
Tau specificity scorei

Tau specificity score is a numerical indicator of the specificity of the gene expression across cells or tissues. The value ranges from 0 and 1, where 0 indicates identical expression across all cells/tissue types, while 1 indicates expression in a single cell/tissue type.

0.98
Cell line distributioni

RNA distribution category based on RNA sequencing data from cancer cell lines in the Human Protein Atlas grouped according to type of cancer. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.

Detected in single
Protein evidencei

Evidence score for genes based on UniProt protein existence (UniProt evidence); neXtProt protein existence (neXtProt evidence);and a Human Protein Atlas antibody- or RNA based score (HPA evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable.

Evidence at protein level
CELL LINE GROUPSi

This figure is comparatively showing RNA level (nTPM) and Protein level (nRPX) of various cell line groups of this particular gene. It is possible to reorder the Barchart by the levels of RNA expression or the cell line group names.

Cell line categories
Alphabetical
Expression
RNA specificity: Cancer enriched (Leukemia)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines.The analyzed cell lines are grouped according to cancer type. Detailed information about the groups is revealed by hovering over the corresponding bar in the chart. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cancer cell line group. The size of the circle corresponds to the median Normalized Relative Protein Expression (nRPX) for the cell lines with MS data in each group, the color represents the tissue type to which the cancer belongs with the intensity of the color reflecting the percentage of the cell lines in the group showing expression of the protein according to MS data. A white circle means that the protein was not detected by MS in corresponding cell lines, while no circle means that MS data was not available for the cell lines.

Please refer to the method of this section for more details.

COMMON CELL LINESi

Similar to the cell line group figure above, this figure is relatively comparing RNA level (nTPM) and Protein level (nRPX) of each cell line in the cell line group of this particular gene. It is possible to reorder the Barchart by the levels of RNA expression or the cell line group names.

Alphabetical
Expression
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.


EXPRESSION CLUSTERING & CORRELATIONi

The RNA data was used to cluster genes according to their expression across samples. The resulting clusters have been manually annotated to describe common features in terms of function and specificity. The annotation of the cluster is displayed together with a confidence score of the gene's assignment to the cluster. The confidence is calculated as the fraction of times the gene was assigned to this cluster in repeated calculations and is reported between 0 to 1, where 1 is the highest possible confidence. The clustering results are shown in a UMAP, where the cluster this gene was assigned to is highlighted as a colored area in which most of the cluster genes reside. A table shows the 15 most similar genes in terms of expression profile.

TPSD1 is part of cluster 49 HMC-1 - Innate immune response with confidencei

Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore reflects how strongly associated it is to the cluster. A confidence of 1 indicates that the gene was assigned to this cluster in all repeated clusterings.

1
136 genes in cluster
Go to interactive expression cluster page
15 nearest neighbours based on cell line RNA expression
Neighbouri

Gene name according to HGNC.

Descriptioni

Gene description according to HGNC.

Correlationi

Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.

Clusteri

ID of the expression cluster of the neighboring gene.

TPSB2 Tryptase beta 2 0.9763 49
GP1BB Glycoprotein Ib platelet subunit beta 0.6224 49
GFI1B Growth factor independent 1B transcriptional repressor 0.6205 47
ITGA2B Integrin subunit alpha 2b 0.5817 47
SIGLEC12 Sialic acid binding Ig like lectin 12 0.5761 49
C3orf80 Chromosome 3 open reading frame 80 0.5149 49
TYROBP Transmembrane immune signaling adaptor TYROBP 0.5128 49
CSF2RB Colony stimulating factor 2 receptor subunit beta 0.4870 49
LYL1 LYL1 basic helix-loop-helix family member 0.4770 14
ENSG00000254979 Novel protein 0.4766 49
MS4A2 Membrane spanning 4-domains A2 0.4671 47
GPR141 G protein-coupled receptor 141 0.4671 49
LTC4S Leukotriene C4 synthase 0.4579 49
PSTPIP2 Proline-serine-threonine phosphatase interacting protein 2 0.4444 51
TPSAB1 Tryptase alpha/beta 1 0.4390 49

CELL LINE DATA
Alphabetical
Expression
Adrenocortical cancer (n=1)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Bile duct cancer (n=7)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Bladder cancer (n=26)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Bone cancer (n=21)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Brain cancer (n=80)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Breast cancer (n=62)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Cervical cancer (n=8)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Colorectal cancer (n=63)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Esophageal cancer (n=27)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Gallbladder cancer (n=1)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Gastric cancer (n=42)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Head and Neck cancer (n=38)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Kidney cancer (n=35)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Leukemia (n=93)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Liver cancer (n=24)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Lung cancer (n=232)


RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Lymphoma (n=76)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Myeloma (n=34)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Neuroblastoma (n=17)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Non-cancerous (n=63)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Ovarian cancer (n=59)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Pancreatic cancer (n=46)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Prostate cancer (n=8)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Rhabdoid (n=14)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Sarcoma (n=15)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Skin cancer (n=62)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Testis cancer (n=1)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Thyroid cancer (n=11)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Uncategorized (n=11)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Uterine cancer (n=29)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

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