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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
34.9
nTPM
HPA:
26.2
nTPM
GTEx:
34.9
nTPM
FANTOM5:
26.5
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA045046
Antibody HPA056027
Cholangiocytes
Not detected
Not detected
Hepatocytes
Medium
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
26.2
Female, age 60
Liver sample 21 nTPM: 3.3
Male, age 54
Liver sample 23 nTPM: 31.3
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 3.3
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 4.6
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 15.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 0.7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 96
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 2.7
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 102.1
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 2.1
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
34.9
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 34.9
Samples: 226
Max nTPM: 362.6
Min nTPM: 0.0
Std nTPM: 57.5
Median nTPM: 5.7
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
362.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
329.9
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
281.9
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
244.3
GTEX-11GSP-0626-SM-5986T
60-69 years, female
233.9
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
197.0
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
195.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
184.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
169.4
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
167.3
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
157.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
143.5
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
139.5
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
129.6
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
126.3
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
125.8
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
120.3
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
120.2
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
114.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
107.2
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
103.4
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
97.3
GTEX-RU72-1426-SM-46MUF
50-59 years, female
97.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
97.2
GTEX-RN64-1826-SM-48FDV
50-59 years, male
91.6
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
88.9
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
88.4
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
88.0
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
82.1
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
81.9
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
81.2
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
80.3
GTEX-R53T-0326-SM-48FEC
50-59 years, female
79.7
GTEX-Q734-0326-SM-48U15
40-49 years, female
78.4
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
78.1
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
76.9
GTEX-QEL4-1226-SM-447A4
50-59 years, male
76.4
GTEX-YECK-1926-SM-4W21H
60-69 years, male
75.9
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
75.9
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
74.9
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
73.8
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
73.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
71.3
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
64.2
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
63.6
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
63.2
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
62.4
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
62.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
60.2
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
60.0
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
58.7
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
58.6
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
57.6
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
57.5
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
56.0
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
54.8
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
54.4
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
53.7
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
51.7
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
50.6
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
50.3
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
50.0
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
49.1
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
48.3
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
43.8
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
43.1
GTEX-1B933-1226-SM-731DW
50-59 years, female
39.8
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
38.8
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
38.6
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
37.4
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
37.2
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
35.4
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
33.8
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
32.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
32.4
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
32.0
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
28.9
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
28.7
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
25.2
GTEX-144GL-1426-SM-79OMA
50-59 years, male
24.8
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
24.1
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
20.3
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
19.8
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
17.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
17.3
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
17.0
GTEX-13113-1326-SM-5GCOI
60-69 years, female
16.6
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
16.4
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
16.3
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
15.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
14.1
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
13.1
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
12.6
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
11.9
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
11.3
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
11.2
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
11.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
10.6
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
10.5
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
10.4
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
10.2
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
9.6
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
9.5
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
8.5
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
7.1
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
6.7
GTEX-1399T-0826-SM-5IFES
60-69 years, male
6.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
6.5
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
6.5
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
6.3
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
5.9
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
5.8
GTEX-X261-1726-SM-4PQYT
50-59 years, male
5.8
GTEX-14PHX-0526-SM-664NW
50-59 years, male
5.7
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
5.7
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
5.6
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
5.6
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
5.4
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
5.4
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
5.3
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
5.1
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
5.1
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
4.9
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
4.9
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
4.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
4.3
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
4.2
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
4.1
GTEX-14E7W-1526-SM-6871X
70-79 years, male
4.1
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
4.0
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
3.8
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
3.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
3.6
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
3.6
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
3.5
GTEX-18A66-2026-SM-7189C
60-69 years, male
3.4
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
2.9
GTEX-18465-1626-SM-7LG6N
50-59 years, male
2.8
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
2.8
GTEX-1B932-1426-SM-793AN
40-49 years, female
2.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
2.5
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
2.4
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
2.3
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
2.2
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
2.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
2.1
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
2.0
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
2.0
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
2.0
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
1.9
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
1.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
1.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
1.7
GTEX-14JG1-1626-SM-664NH
40-49 years, male
1.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
1.7
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
1.6
GTEX-17HHE-0126-SM-79398
50-59 years, male
1.5
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
1.5
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
1.5
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
1.5
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
1.4
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
1.4
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
1.4
GTEX-QESD-2026-SM-447BI
20-29 years, male
1.4
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
1.3
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
1.3
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
1.3
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
1.3
GTEX-11ZUS-2526-SM-59872
30-39 years, male
1.2
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
1.2
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
1.2
GTEX-12696-0826-SM-5EGGE
60-69 years, male
1.1
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
1.1
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
1.1
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
1.0
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
1.0
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
0.9
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
0.9
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
0.9
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
0.9
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
0.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
0.8
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
0.8
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
0.8
GTEX-REY6-1226-SM-48FDR
60-69 years, male
0.8
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
0.8
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
0.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
0.8
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
0.7
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
0.7
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
0.7
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
0.7
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
0.7
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
0.7
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
0.6
GTEX-14PJO-1726-SM-68719
60-69 years, male
0.6
GTEX-18A7A-1526-SM-72D69
50-59 years, female
0.6
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
0.6
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
0.6
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
0.6
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
0.6
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
0.5
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
0.5
GTEX-P78B-1326-SM-3P611
40-49 years, female
0.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
0.5
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
0.5
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
0.5
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
0.5
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
0.4
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
0.4
GTEX-S32W-1926-SM-4AD63
50-59 years, female
0.4
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
0.4
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
0.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
0.3
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
0.2
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
0.2
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
0.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
0.2
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
0.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
0.2
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
0.2
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
0.1
GTEX-S33H-1626-SM-4AD68
30-39 years, male
0.1
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
0.1
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
0.1
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
0.0
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
