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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:42.1 nTPM
HPA Brain:50.6 nTPM
GTEx:42.1 nTPM
FANTOM5:78.5 Scaled Tags Per Million
Pig:57.5 nTPM
Mouse:107.0 nTPM
Allen mouse:8.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

50.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 42.2
2019 Male, age 18, unknown 52.1
1870 Female, age 42, unknown 45.0
2586 Male, age 75, left hemisphere 44.8
1833 Male, age 53, unknown 44.1
2411 Female, age 72, unknown 43.7
1827 Male, age 72, unknown 41.3
2219 Male, age 76, both hemispheres 39.6
1830 Male, age 51, unknown 38.9
2828 Female, age 72, unknown 37.5
2666 Male, age 74, left hemisphere 35.5
Dorsal raphe nucleus
nTPM: 50.3
2298 Female, age 72, unknown 56.8
2047 Male, age 72, unknown 53.6
2016 Female, age 72, unknown 47.7
1828 Male, age 53, unknown 46.9
2750 Male, age 76, both hemispheres 46.4
Inferior colliculus
nTPM: 44.5
1848 Female, age 42, unknown 46.6
2097 Female, age 72, unknown 46.1
1890 Male, age 53, unknown 45.8
2849 Male, age 72, unknown 39.5
Median raphe nucleus
nTPM: 50.6
2220 Male, age 76, midline 50.6
Periaquaductal grey, anterior
nTPM: 44.3
1947 Male, age 18, unknown 48.8
2502 Female, age 75, unknown 45.8
1795 Male, age 51, unknown 38.3
Periaquaductal grey, dorsal
nTPM: 39.2
2464 Female, age 72, unknown 44.4
2850 Male, age 76, both hemispheres 39.6
1840 Male, age 53, unknown 36.7
1831 Male, age 72, unknown 36.2
Periaquaductal grey, lateral
nTPM: 38.8
2272 Male, age 74, both hemispheres 46.0
2053 Male, age 18, unknown 36.3
2140 Male, age 76, both hemispheres 34.2
Pretectal area
nTPM: 45.7
1817 Female, age 42, unknown 53.7
2224 Female, age 72, unknown 51.5
2273 Male, age 74, both hemispheres 48.6
2007 Male, age 72, unknown 48.5
2407 Male, age 75, both hemispheres 47.3
1815 Male, age 53, unknown 47.1
2667 Female, age 75, unknown 46.7
1944 Female, age 72, unknown 43.7
1816 Male, age 51, unknown 40.1
2316 Male, age 76, right hemisphere 38.2
2825 Male, age 18, unknown 37.5
Red nucleus
nTPM: 44.1
1821 Female, age 72, unknown 59.7
1865 Male, age 51, unknown 54.5
1904 Male, age 53, unknown 48.5
1954 Female, age 42, unknown 46.0
2785 Male, age 18, unknown 44.7
2725 Female, age 75, unknown 43.3
2769 Male, age 72, unknown 42.8
2823 Male, age 76, right hemisphere 41.8
2227 Male, age 72, unknown 41.5
2503 Female, age 72, unknown 39.7
2584 Male, age 75, left hemisphere 36.6
2588 Male, age 74, left hemisphere 29.5
Substantia nigra
nTPM: 46.3
2241 Male, age 72, unknown 54.0
1851 Male, age 51, unknown 52.2
1916 Female, age 42, unknown 50.7
1889 Female, age 72, unknown 49.0
1941 Male, age 53, unknown 48.6
2409 Female, age 72, unknown 48.2
2699 Male, age 18, unknown 47.3
2590 Female, age 75, unknown 43.5
2583 Male, age 75, right hemisphere 36.4
2665 Male, age 74, both hemispheres 32.8
Superior colliculus
nTPM: 41.8
2587 Male, age 74, left hemisphere 49.5
1839 Male, age 51, unknown 45.7
1913 Female, age 42, unknown 45.0
1895 Male, age 76, right hemisphere 42.5
2668 Female, age 75, unknown 41.2
2664 Male, age 75, both hemispheres 40.9
1995 Male, age 72, unknown 40.5
1796 Male, age 53, unknown 39.4
2261 Male, age 18, unknown 36.5
2087 Female, age 72, unknown 36.4
Ventral tegmental area
nTPM: 47.2
2410 Female, age 72, unknown 55.7
2218 Male, age 76, both hemispheres 48.5
2223 Female, age 72, unknown 47.7
1915 Female, age 42, unknown 47.1
2021 Male, age 53, unknown 42.4
1942 Male, age 51, unknown 41.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

42.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 42.1
Samples: 139

Max nTPM: 68.4
Min nTPM: 23.7
Std nTPM: 8.3
Median nTPM: 40.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 68.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 66.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 62.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 61.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 60.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 60.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 60.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 60.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 58.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 56.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 56.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 56.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 55.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 54.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 54.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 54.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 54.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 53.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 50.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 49.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 49.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 49.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 49.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 48.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 48.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 48.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 48.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 48.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 48.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 47.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 47.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 47.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 46.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 46.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 45.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 45.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 45.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 45.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 44.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 44.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 44.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 44.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 44.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 44.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 43.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 43.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 43.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 43.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 43.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 43.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 43.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 42.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 42.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 42.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 42.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 42.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 42.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 42.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 42.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 42.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 42.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 42.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 41.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 41.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 41.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 41.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 41.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 41.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 40.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 40.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 40.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 40.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 40.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 40.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 40.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 40.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 39.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 39.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 39.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 39.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 39.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 39.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 39.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 39.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 39.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 39.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 39.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 38.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 38.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 38.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 38.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 38.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 38.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 37.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 37.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 37.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 37.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 37.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 37.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 37.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 36.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 36.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 36.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 36.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 36.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 36.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 35.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 35.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 35.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 35.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 35.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 35.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 35.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 35.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 35.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 35.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 34.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 34.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 34.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 34.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 34.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 34.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 34.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 33.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 33.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 32.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 32.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 32.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 31.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 31.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 31.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 31.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 30.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 30.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 30.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 28.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 27.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 27.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 23.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

78.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 78.5
FF:10158-103A5 76 years, female 78.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 52.6
Samples: 4

Max nTPM: 60.2
Min nTPM: 46.7
Sample A Female 60.2
Sample B Female 46.7
Sample C Male 46.7
Sample D Male 56.6
Midbrain
nTPM: 57.5
Samples: 4

Max nTPM: 81.8
Min nTPM: 43.4
Sample A Female 81.8
Sample B Female 54.3
Sample C Male 50.4
Sample D Male 43.4
Periaqueductal gray
nTPM: 43.9
Samples: 3

Max nTPM: 45.2
Min nTPM: 42.8
Sample B Female 45.2
Sample C Male 42.8
Sample D Male 43.8
Superior colliculi
nTPM: 52.7
Samples: 4

Max nTPM: 59.9
Min nTPM: 42.7
Sample A Female 55.5
Sample B Female 42.7
Sample C Male 59.9
Sample D Male 52.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

107.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 107.0
Samples: 4

Max nTPM: 112.3
Min nTPM: 104.4
Sample A Male 112.3
Sample B Male 105.5
Sample C Female 105.8
Sample D Female 104.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

8.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.7
279 Antisense, RP_Baylor_253892, Mouse strain C57BL/6J (56 days, male) 8.7
278 Antisense, RP_Baylor_253892, Mouse strain C57BL/6J (56 days, male) 4.4

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