We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene namei
Official gene symbol, which is typically a short form of the gene name, according to HGNC.
All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.
Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.
Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).
The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Chromosome
14
Cytoband
q23.1
Chromosome location (bp)
58408495 - 58427531
Number of transcriptsi
Number of protein-coding transcripts from the gene as defined by Ensembl.
Useful information about the protein provided by UniProt.
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space....show less
Molecular function (UniProt)i
Keywords assigned by UniProt to proteins due to their particular molecular function.
Chaperone
Biological process (UniProt)i
Keywords assigned by UniProt to proteins because they are involved in a particular biological process.
Protein transport, Translocation, Transport
Ligand (UniProt)i
Keywords assigned by UniProt to proteins because they bind, are associated with, or whose activity is dependent of some molecule.
Metal-binding, Zinc
Gene summary (Entrez)i
Useful information about the gene from Entrez
TIMM9 belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM, Apr 2004]...show less
PROTEIN INFORMATIONi
The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.
The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.
The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515[protein binding] GO:0005739[mitochondrion] GO:0005743[mitochondrial inner membrane] GO:0005758[mitochondrial intermembrane space] GO:0006626[protein targeting to mitochondrion] GO:0007605[sensory perception of sound] GO:0008270[zinc ion binding] GO:0015031[protein transport] GO:0016020[membrane] GO:0032977[membrane insertase activity] GO:0042719[mitochondrial intermembrane space protein transporter complex] GO:0042721[TIM22 mitochondrial import inner membrane insertion complex] GO:0042803[protein homodimerization activity] GO:0045039[protein insertion into mitochondrial inner membrane] GO:0046872[metal ion binding] GO:0051087[chaperone binding]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515[protein binding] GO:0005739[mitochondrion] GO:0005743[mitochondrial inner membrane] GO:0005758[mitochondrial intermembrane space] GO:0006626[protein targeting to mitochondrion] GO:0007605[sensory perception of sound] GO:0008270[zinc ion binding] GO:0015031[protein transport] GO:0016020[membrane] GO:0032977[membrane insertase activity] GO:0042719[mitochondrial intermembrane space protein transporter complex] GO:0042721[TIM22 mitochondrial import inner membrane insertion complex] GO:0042803[protein homodimerization activity] GO:0045039[protein insertion into mitochondrial inner membrane] GO:0046872[metal ion binding] GO:0051087[chaperone binding]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515[protein binding] GO:0005739[mitochondrion] GO:0005743[mitochondrial inner membrane] GO:0005758[mitochondrial intermembrane space] GO:0006626[protein targeting to mitochondrion] GO:0007605[sensory perception of sound] GO:0008270[zinc ion binding] GO:0015031[protein transport] GO:0016020[membrane] GO:0032977[membrane insertase activity] GO:0042719[mitochondrial intermembrane space protein transporter complex] GO:0042721[TIM22 mitochondrial import inner membrane insertion complex] GO:0042803[protein homodimerization activity] GO:0045039[protein insertion into mitochondrial inner membrane] GO:0046872[metal ion binding] GO:0051087[chaperone binding]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515[protein binding] GO:0005739[mitochondrion] GO:0005743[mitochondrial inner membrane] GO:0005758[mitochondrial intermembrane space] GO:0006626[protein targeting to mitochondrion] GO:0007605[sensory perception of sound] GO:0008270[zinc ion binding] GO:0015031[protein transport] GO:0016020[membrane] GO:0032977[membrane insertase activity] GO:0042719[mitochondrial intermembrane space protein transporter complex] GO:0042721[TIM22 mitochondrial import inner membrane insertion complex] GO:0042803[protein homodimerization activity] GO:0045039[protein insertion into mitochondrial inner membrane] GO:0046872[metal ion binding] GO:0051087[chaperone binding]
The Human Protein Atlas project is funded
